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2,4-Dimethylaniline-6-Sulfonic Acid

    • Product Name 2,4-Dimethylaniline-6-Sulfonic Acid
    • Alias 2,4-Xylidine-6-sulfonic acid
    • Einecs 250-717-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    260141

    Chemical Name 2,4-Dimethylaniline-6-Sulfonic Acid
    Molecular Formula C8H11NO3S
    Molecular Weight 201.25 g/mol
    Cas Number 88-21-1
    Appearance Light brown to gray solid
    Melting Point 210-213°C
    Solubility In Water Soluble
    Synonyms 6-Sulfo-2,4-xylidine
    Smiles CC1=CC(N)=C(C)C=C1S(=O)(=O)O
    Storage Conditions Store in a cool, dry place

    As an accredited 2,4-Dimethylaniline-6-Sulfonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 100g 2,4-Dimethylaniline-6-Sulfonic Acid is packaged in a sealed amber glass bottle with tamper-evident cap and hazard labeling.
    Shipping 2,4-Dimethylaniline-6-Sulfonic Acid should be shipped in sealed, leak-proof containers, clearly labeled according to chemical safety regulations. Ensure packaging is compatible with acids and anilines. Handle with care, avoid extreme temperatures, and comply with local and international hazardous material transport guidelines. Include relevant SDS documentation for safe and legal transit.
    Storage 2,4-Dimethylaniline-6-sulfonic acid should be stored in a tightly sealed container, away from moisture, heat, and direct sunlight. Store in a cool, dry, and well-ventilated area, isolated from incompatible substances such as strong oxidizers and bases. Clearly label the container and ensure it is kept in a designated chemical storage area, following all relevant safety guidelines.
    Application of 2,4-Dimethylaniline-6-Sulfonic Acid

    Applications of 2,4-Dimethylaniline-6-Sulfonic Acid in Industrial Manufacturing

    As a dedicated producer, we supply 2,4-Dimethylaniline-6-Sulfonic Acid for specific downstream sectors that demand high-quality intermediates and optimized process integration. This compound plays an essential role in colorants, specialty chemicals, and other functional organic synthesis, contributing directly to formulation and yield control in advanced manufacturing environments.

    1. Azo Dye Intermediates for Synthetic Fiber Coloring

    This material enters as a critical coupling component in the synthesis of azo dyes, especially for polyester, nylon, and acetate fiber coloration. Its sulfonic acid group supports water solubility and improved fixation on synthetic fiber substrates. Downstream dye manufacturing operations use controlled diazotization followed by azo coupling where the ratio affects color fastness and shade depth. Stringent wash fastness and migration resistance guide formulation adjustments for various textile applications.

    Industry compliance standards

    • Oeko-Tex Standard 100 (specific restricted substance criteria)
    • REACH Annex XVII for dye component registration
    • ZDHC MRSL compliance for effluent and residue
    • ISO 105-C06:2010 wash fastness protocols

    Typical usage ratio

    • 5–18% by weight relative to total diazo/coupling system, adjusted based on desired color strength and shade
    • Adjusted down to 2–4% for pastel or muted tone batches
    • Process audits usually optimize for substrate type and end-use conditions

    Downstream process integration

    • Inserted after primary diazotization reaction step in dye synthesis
    • Pre-neutralized and filtered for direct coupling reactions
    • Batch blending with coupling components under pH-controlled conditions
    • Purification by precipitation and drying prior to application in textile dyeing lines

    Final product types

    • Disperse dyes for polyester yarn
    • Acid dyes for polyamide substrates
    • Direct dyes for blended fabrics
    • Specialty pigments used in industrial textile printing

    2. Sulfonated Aromatic Compound Synthesis for Photosensitive Materials

    In the production of photoactive intermediates, this chemical provides both electron-donating methyl groups and functionalizable sulfonic acid for customized photoreactive moieties. Semiconductor and electronics sectors specify these derivatives for use in photosensitive coatings and lithographic resists. The process requires high-purity feedstock, and formulation strictly controls the proportion to balance optical density and residual solubility after exposure and development steps.

    Industry compliance standards

    • SEMI C93 trace metal impurity limits
    • RoHS Directive (2011/65/EU) for photochemical additives
    • IPC-4552 standards for surface insulation resistance in photosensitive coating applications
    • ISO 10677 for photochemical film and resist testing

    Typical usage ratio

    • 0.8–2.2% by weight in photoinitiator blends
    • Higher loadings (up to 4%) for anti-halation and anti-bleed layers
    • Fine-tuned according to exposure time and resolution requirements

    Downstream process integration

    • Dissolution into pre-polymer or resin base before solvent casting
    • Reactive blending during photosensitizer dispersion in liquid formulations
    • Integrated quality checks for sulfonate retention post-formulation
    • Application to film or wafer substrate via dip, spin, or spray coat process

    Final product types

    • Positive and negative photoresists for PCB and IC manufacturing
    • Photosensitive inks for LCD panels
    • Sensitized imaging layers for lithographic plate making
    • Specialty photopolymers for microfabrication

    3. Pharmaceutical Intermediate for Sulfonamide Drug Synthesis

    This specialty material integrates into multi-step syntheses of sulfonamide-based pharmaceuticals, where purity and isomeric control remain critical. Manufacturers select this compound for its specific aromatic substitution pattern, facilitating targeted functionalization in small-molecule APIs. Batch records enumerate precise input ratios to maximize reaction selectivity and downstream process yield, with all processing under validated GMP conditions.

    Industry compliance standards

    • ICH Q7 GMP Guidelines for Active Pharmaceutical Ingredients
    • USP/NF standards for sulfonamide intermediates
    • 21 CFR Part 210/211 for pharmaceutical manufacturing controls
    • European Pharmacopoeia 10.0 (Ph. Eur.) monographs

    Typical usage ratio

    • 0.5–1.2 molar equivalents in stepwise Grignard and sulfonation reactions
    • Synergistic adjustments with secondary amines to balance conversion rate
    • Process analytical technology (PAT) guides adjustment in pilot to commercial scale

    Downstream process integration

    • Direct input after preliminary aromatic nitration step
    • Purification via crystallization and controlled pH extraction
    • Chemical conversion tracking by in-process HPLC and NMR
    • Final API isolation via solvent removal and recrystallization

    Final product types

    • Sulfonamide antimicrobial APIs
    • Antidiabetic compounds using sulfonic acid intermediates
    • Veterinary medicine precursors
    • Bulk pharmaceutical intermediates for contract synthesis

    4. Intermediate in Specialty Pigment Manufacturing

    Our product serves as a functional building block for certain high-performance azo and phthalocyanine pigments, providing tailored sulfonation and electron-donating substitution for stability and color intensity. Pigment manufacturers depend on its consistent quality to achieve narrow particle distribution and dispersibility in plastics and coatings. The application involves coupling and heat treatment steps under controlled atmospheres, optimizing pigment shade and opacity.

    Industry compliance standards

    • EN 71-3 for toy and children’s product pigments
    • ASTM D476 standard classification for pigment grade
    • Food Contact Materials Regulation (EU) No 10/2011 for some packaging pigment applications
    • REACH SVHC assessment for pigment precursors

    Typical usage ratio

    • 3–10% by mass within pigment synthesis batch
    • Adjusted based on target chroma and compatibility with resin systems
    • Higher end of range for deep hues and extended weatherability

    Downstream process integration

    • Introduced after initial condensation polymerization with other aromatic diamines
    • Controlled heating cycle for pigment nucleation and particle growth
    • Mechanical stabilization and wet milling for dispersion
    • Final drying prior to masterbatch/dispersion compounding

    Final product types

    • Color masterbatches for plastic extrusion
    • Architectural and industrial coatings
    • Automotive pigments and specialty finishes
    • Printing ink concentrates
    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing 2,4-Dimethylaniline-6-Sulfonic Acid: Practical Insights from the Manufacturer

    A Reliable Workhorse in Dye and Fine Chemical Production

    Making reliable, high-purity chemicals means staying up late with the equipment and putting your focus on every batch. 2,4-Dimethylaniline-6-Sulfonic Acid, better known among chemists as a key intermediate, stands out due to its steady performance and ease of downstream reactions. Since the earliest days of our workshop, this compound filled a special niche for those working on azo dyes and specialty chemicals. Our team took the hands-on approach when designing the process: we monitor each reaction stage, control sulfonation rates, and work to avoid unwanted impurities that have frustrated so many users in this market.

    What Sets This Acid Apart

    Colleagues in the dye industry appreciate that 2,4-Dimethylaniline-6-Sulfonic Acid brings high selectivity in coupling steps, especially for vivid color development. The methyl groups on the aromatic ring steer the reactivity, letting manufacturers avoid side reactions that waste time and resources. Operators using this intermediate see fewer purification bottlenecks, particularly in applications where clarity and brightness matter.

    Compared with unsubstituted aniline sulfonic acids, adding two methyl substituents at the 2 and 4 positions gives a chemical stability that means longer shelf-life and less degradation, even when storage conditions are less than ideal. Our technicians stress-test each batch against heat swing and air exposure, and report lower discoloration and off-odors compared to single-position analogs.

    Typical Specifications Our Team Deliver

    Production at scale poses a challenge, but our plants keep tight controls on content and purity. Most batches meet a content target exceeding 98% by weight, with trace-level control of inorganic salts. Moisture gets handled in the drying step, using carefully calibrated vacuum ovens. After observing customer frustration with poorly handled crystallization, we invested in centrifugal separation and multi-stage filtration, driving down insolubles content.

    Every drum of product comes off the line with particle sizing that supports straightforward solution preparation. Chemists working on large-batch dye syntheses tell us they spend less time dissolving our product in alkaline phase, and wastes clogging their lines drop off. Less time reclaiming equipment equals more uptime—feedback we value from repeat customers.

    Bridging Laboratory Reliability and Industrial Scale-Up

    Scale-up never goes exactly like it looks in the catalogs. Researchers sourcing high-purity intermediates hit a wall as soon as they step up from grams to kilos. Our facility faces the same problems—hot spots in reactors, exotherms pushing unwanted reactions, and batch-to-batch drift if you ignore the details. We grew the process with a focus on consistency, running small pre-production lots and scaling only after each critical control point passed our internal benchmarks.

    We listen to our partners in dyes and pigments who complain about trace metals and by-products in sulfonic acids from less careful producers. Their feedback shaped our washing and purification strategies, so the final product serves color makers requiring low background noise. If your application hinges on headline color strength in finished goods, you’ll notice less batchwise tuning when using our 2,4-Dimethylaniline-6-Sulfonic Acid.

    Key Uses and Value in Applied Sectors

    Talking directly with application chemists taught us where our material solves headaches. The most common end use stays in the azo dye segment, particularly those formulas needing crisp, long-lasting shades for textiles. Textile processors’ feedback led us to improve the rinsability and minimize inorganic carryover, which can lead to spots and uneven dyeing. In paper colorants, formulators seek the right balance between brightness and bleed resistance; they’ve reported fewer unresolved color specks with our trusted process route.

    Manufacturers in the pharmaceuticals sector have tested the compound’s performance as a synthetic intermediate. In routes based on aromatic substitution, the methyl groups block undesired positions, giving higher yield of target molecules. The high purity grade supports demanding applications, so you’re not building time-consuming clean-up steps into your workflow.

    Occasionally, agricultural researchers approach us with novel uses in crop-protection intermediates. While less common than in dyes, their projects demand consistent sulfonic position and minimal color drift. Clean starting points matter for downstream catalyst and process control, areas where we often work directly with process developers to ensure batch repeatability.

    What We’ve Learned About Handling and Compatibility

    Over many years, we tracked field problems that reached back to early production design. Mis-handling during storage can compromise some aromatic sulfonic acids, especially under humid conditions. So, we pay extra attention to drying and packaging—double-bagged, moisture-proof liners have saved many a batch from caking or clumping during shipping across humid regions.

    The chemical boasts good solubility in basic aqueous phases, which most color makers exploit. Users working at plant scale say they save on mixing time and get less undissolved residue in process tanks. With proper pH management, they see high reproducibility and solid yields in coupling or diazotization stages.

    We’ve collaborated with users integrating the compound into polymer matrices for specialty plastics and functional materials. Their main concern was thermal stability—and once again, the methyl groups seem to help. Our tests, backed up with collaborating labs, show enhanced color fastness after compounding, and less degradation after exposure to heat and light.

    Comparing With Other Related Aromatic Sulfonic Acids

    Labs with broad portfolios often ask about difference between our 2,4-dimethyl derivative and simpler aniline sulfonic acids or mono-methyl variants. The dually substituted product shows more controlled reactivity in azo coupling; it fends off polymer formation or tarry by-products that create waste and slow cleaning. In blends, dyes based on 2,4-Dimethylaniline-6-Sulfonic Acid display less shift during storage, with colorfastness holding up longer on finished fabric or paper.

    Our technical staff ran head-to-head pilot tests using both mono- and di-methyl isomers. The di-methyl version gives a narrower melting range and more granular control over color hues, letting dye-makers match shades from batch to batch. Frustrated buyers often start with the cheaper mono-methyl derivative, only to circle back after struggling with inconsistent hues and clogging at the filtration stage.

    Quality Control: Real-World Feedback Shapes Our Approach

    Stories from factory lines often shape the tweaks we introduce for better results. In the early years, some of our output showed variable crystal habit, and end-users flagged poor color dispersibility. In response, we upgraded both our filtration and recrystallization steps, achieving sharper melting points and a cleaner, uniform product. Return customers in the finishing departments tell us they no longer see batch-specific issues, highlighting the value of tight process management.

    We encourage field engineers and color chemists to share problem samples with us, so we can pinpoint root causes. Feedback from a major dye house led to a review of sulfonate salt levels—a few bad shipments downstream clued us in that the high salt built up during final washing was causing out-of-spec dye lots. We added conductivity checks and reengineered the wash sequence, cutting salt carryover and helping our customers avoid costly rejects.

    Supply Chain, Bulk Delivery, and the Human Element

    Supplying a chemical that hits the spec sheet means nothing without sure logistics. Production batches run year-round, but real world demand comes in cycles, driven by scripts outside our control—textile peaks, regulatory changes, supply chain hiccups. Keeping a robust stockpile of raw materials and product-in-process gives us breathing room, and we've built relationships with logistics teams to ensure safe, timely delivery.

    Bulk shipments move in lined drums, but we also support special orders based on custom packaging needs. During the initial pandemic supply crunch, resourcefulness paid off—we organized in-house filling and cross-trained the crew so we kept up with surges in demand. Clients who struggled with previous suppliers reached out, and our flexible packaging lines helped them avoid stopping their own lines.

    From each truckload or container, we pull random samples, run control tests anew, and hold back material if it even hints at deviation. This strict approach prevents downstream surprises. All products ship with real batch data, not generic reports, empowering receiving labs to confirm specs before use.

    Environmental Considerations and Responsible Production

    Manufacturing aromatic sulfonic acids creates some tricky waste streams—acidic effluents, off-gases, and residual organic content. Running a responsible operation means handling all streams without cutting corners. We invested in on-site treatment units, including acid neutralizers and activated carbon beds, after earlier years trying to outsource incomplete waste handling. This keeps regulators and neighbors satisfied, but more importantly, it gives our team confidence that every operation meets our standards.

    We track each step’s input and output, minimizing raw material wastage through close monitoring and automated dosing. Recent process tweaks let us cut the sulfonation excess, recapture valuable materials, and reduce energy draw at each purification stage. Employees regularly suggest improvements to boost efficiency—these little changes add up over thousands of kilograms produced every month. Our team members take pride in making a product that doesn’t leave a mess behind for someone else to clean up.

    Research Partnerships and Continuous Improvement

    The best ideas often come from those who use the product daily. Researchers approach us looking for higher-purity custom grades, new isomer ratios, or alternative solvent compatibility. We operate a dedicated applications lab where our chemists mimic real-world use—dissolving, blending, testing output in end-product scenarios. Insights from these collaborations filter back into mainline production, leading to tighter specs, improved shelf-life, and smarter packaging.

    We also run regular benchmarking against global standards, working to beat not just minimum legal requirements, but the best practices accepted in advanced regions. Our in-house analytics lab runs HPLC and titration on every lot, and we compare results to application benchmarks from partners. These efforts ensure downstream users gain not only regulatory compliance but also hands-on predictability.

    Building Trust with End-Users

    In more than a decade of producing 2,4-Dimethylaniline-6-Sulfonic Acid, trust with users stands as the real measure of success. Buyers—from small batch custom dye shops to large integrated factories—return because they know what comes off our lines matches their real-world process needs, batch after batch. Building on honest conversations, not just price lists, gives us the foundation to solve unexpected problems together.

    We keep communication lines open, and our technical experts spend time with users walking through process challenges. Regular knowledge sharing means we spot trends before they become issues. If a customer uncovers a new application or runs into scale-up hurdles, our lab stands ready to study, adapt, and deliver on practical solutions.

    Making chemicals for daily industrial use rarely grabs headlines, but reliability under pressure brings real-world impact. Each lesson learned—whether it’s a tweak in the crystallization step, a new insight from a dye house partner, or a field report on color performance—feeds back into our collective knowledge. This hands-on spirit keeps both our products and our reputation strong with customers worldwide.