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2,4-Dichlorobenzyl Alcohol

    • Product Name 2,4-Dichlorobenzyl Alcohol
    • Alias DCBA
    • Einecs 202-307-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    810855

    Chemicalname 2,4-Dichlorobenzyl Alcohol
    Casnumber 1777-82-8
    Molecularformula C7H6Cl2O
    Molecularweight 177.03 g/mol
    Appearance White crystalline solid
    Meltingpoint 51-53 °C
    Boilingpoint 265 °C
    Solubilitywater Slightly soluble
    Odor Faint aromatic odor
    Density 1.39 g/cm³
    Flashpoint 124 °C
    Refractiveindex 1.595
    Storagetemperature Room temperature
    Purity Typically ≥98%
    Synonyms 2,4-DCBA

    As an accredited 2,4-Dichlorobenzyl Alcohol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2,4-Dichlorobenzyl Alcohol is supplied in a sealed amber glass bottle with a screw cap and safety label.
    Shipping 2,4-Dichlorobenzyl Alcohol is shipped in tightly sealed containers, protected from moisture and incompatible substances. It should be stored in a cool, dry, well-ventilated area. Transportation complies with chemical safety regulations, with labeling indicating its identity and hazards. Handle with care to avoid spills or exposure during transit.
    Storage 2,4-Dichlorobenzyl Alcohol should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Keep the storage area clearly labeled and protected from moisture. Avoid direct sunlight and excessive heat. Use secondary containment to prevent leaks or spills and restrict access to authorized personnel only.
    Application of 2,4-Dichlorobenzyl Alcohol

    Applications of 2,4-Dichlorobenzyl Alcohol in Industrial Manufacturing

    2,4-Dichlorobenzyl Alcohol plays a critical role in downstream specialty chemical sectors. As the original manufacturer, we specialize in supply tailored to the exact requirements of drug synthesis, personal care intermediates, agrochemical formulation, and polymer manufacturing. Below are detailed industrial application scenarios including relevant standards, formulation guidance, and processing integration.

    1. Active Pharmaceutical Ingredient (API) Synthesis for Throat Lozenges and Antiseptics

    Pharmaceutical manufacturers employ 2,4-Dichlorobenzyl Alcohol as a functional intermediate in the formulation of antimicrobial agents for throat lozenges and oral antiseptics. Production processes strictly monitor residual solvent levels and impurity profiles to ensure compliance with pharmacopoeial standards. In API synthesis, control of reaction parameters such as pH, temperature, and mixing rates directly affects yield and final product purity. The alcohol is introduced during amidation or esterification phases, offering broad-spectrum antimicrobial qualities designed for safe oral use. Final dosage forms are prepared after granulation and compression under validated cleanroom environments, requiring rigorous documentation of critical material attributes from source batch upward.

    Industry compliance standards

    • European Pharmacopoeia (Ph. Eur.) monograph for pharmaceutical antimicrobials
    • United States Pharmacopeia (USP) <797> sterile pharmaceutical preparation standards
    • Good Manufacturing Practice (GMP) compliance: EU GMP Part I and ICH Q7
    • REACH registration for pharmaceutical excipients

    Typical usage ratio

    • 0.15%–0.2% w/w in finished throat lozenge formulations (adjusted per regional allowable maximums)
    • Synthesis intermediates: 0.3–0.6 molar equivalents relative to acylating agent during batch synthesis

    Downstream process integration

    • Charged during API intermediate condensation and coupling reaction stages
    • Monitored for presence in in-process QC and validated via HPLC in release testing
    • Granulation step for lozenge manufacturing involves direct wet mixing with excipients
    • Final product packed in blister units under controlled humidity

    Final product types

    • Sugar-free throat lozenges (antibacterial tablets)
    • Oral spray antiseptics
    • Gargle solutions
    • Pharmaceutical toothpaste for clinical oral care

    2. Intermediate for Personal Care Preservative Production

    Manufacturers in the personal care sector utilize 2,4-Dichlorobenzyl Alcohol as a halogenated aromatic intermediate. It enables targeted synthesis of microbicide and preservative components for skin creams, hand sanitizers, and rinse-off products. Material incorporation relies on precise batch addition, under inert atmosphere, preventing oxidative degradation. Downstream blending processes maintain material traceability through validated batch records. Formulators comply with stringent cosmetic safety directives and maintain high-purity standards to minimize allergenicity and other risks in finished consumer goods.

    Industry compliance standards

    • Cosmetics Regulation (EC) No 1223/2009 (EU) — Annex V preservative guidance
    • Personal Care Products Council (PCPC) ingredient safety review
    • ISO 22716:2007 (Cosmetics — Good Manufacturing Practices)
    • IFRA (International Fragrance Association) ingredient purity assessment

    Typical usage ratio

    • 0.1%–0.3% w/w in finished preservative blends
    • Intermediate synthesis: 0.50–0.85 molar equivalents in reaction to produce microbicidal esters

    Downstream process integration

    • Added during aromatic ring derivatization and esterification step
    • Batch blending under nitrogen to reduce contamination risk
    • Quality testing by GC–MS for trace impurities prior to compounding with carrier agents
    • Direct incorporation in emulsion bases during pre-mix preparation

    Final product types

    • Facial cleansing lotions
    • Hand sanitizing gels
    • Preservative systems for paraben-free creams
    • Dermatological emollient formulas

    3. Synthetic Building Block in Agrochemical Formulations

    Agrochemical formulators use 2,4-Dichlorobenzyl Alcohol as a key building block for the synthesis of herbicidal and fungicidal active ingredients. The compound acts as an anchor structure for halogenated benzyl derivatives, allowing downstream functionalization via etherification, esterification, or alkylation. Stringent process controls prevent by-product formation, and traceability from raw material to finished agrochemicals is maintained in alignment with global registration dossiers. Formulation plants conduct multi-stage blending and microencapsulation processes that fixate the active molecule on carrier substrates, optimizing application in both foliar and seed treatment products.

    Industry compliance standards

    • FAO/WHO Specifications for Agricultural Pesticides
    • US EPA Pesticide Registration requirements (FIFRA)
    • ISO 9001:2015 Quality Management Systems for agrochemical manufacturing
    • Sustainable Agriculture Code for safe use and environmental impact minimization

    Typical usage ratio

    • 0.2%–1.5% w/w as intermediate in active ingredient synthesis
    • Active load tailored from 1–10% in microencapsulated seed coatings, adjusted by crop type and field dosage

    Downstream process integration

    • Charged during initial condensation step for halogenated benzyl derivative synthesis
    • Isolated after purification by distillation or recrystallization
    • Blended into concentrated agrochemical emulsions or suspension concentrates
    • Applied in final microencapsulation step for coated fertilizers and seeds

    Final product types

    • Systemic fungicide actives
    • Selective herbicidal granules
    • Seed treatment coatings
    • Pesticide active ingredient precursors

    4. Intermediate for Specialty Polymer and Resin Synthesis

    In the specialty polymer sector, production plants use 2,4-Dichlorobenzyl Alcohol as a functional intermediate for aromatic polyesters, acid-resistant resins, and modified polyurethanes. The compound introduces controlled halogenation that enhances chemical durability and mechanical properties of finished polymers. Manufacturers incorporate the material during polycondensation or curing steps, supervising addition rates and reaction temperature to control chain termination and branching. Product traceability requires batch-level certificate of analysis and compliance with industrial safety protocols for polymer additives.

    Industry compliance standards

    • ISO 9001:2015 for polymer additives and intermediate manufacturing
    • Regulation (EC) No 1907/2006 (REACH) for chemical safety in polymers
    • UL 94 Flammability testing for polymer products
    • Technical Data Sheet (TDS) conformity for application in industrial grade resins

    Typical usage ratio

    • 0.5%–2.0% w/w as monomer or chain-terminating agent in condensation polymerizations
    • Addition levels adjusted based on required halogen content in target polymer matrix

    Downstream process integration

    • Fed during continuous or batch polycondensation to initiate chain-end functionalization
    • Added during resin modification to impart flame retardancy
    • Quality control by GPC and FTIR to verify incorporation
    • Post-polymerization blending into performance resin composites

    Final product types

    • Halogenated polyester resins
    • Acid-resistant tank liners
    • Industrial casting materials
    • Polyurethane foam intermediates with flame-retardant properties
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    Certification & Compliance
    More Introduction

    2,4-Dichlorobenzyl Alcohol: Experience from the Production Line

    2,4-Dichlorobenzyl Alcohol stands out as a familiar compound in our manufacturing halls. Ask anyone who works with it daily, and they’ll tell you it brings a certain steadiness and versatility few other materials match. With a chemical backbone built for reliability, 2,4-Dichlorobenzyl Alcohol earns its reputation through years of handling, processing, and direct feedback from end applications. We offer it as a white crystalline solid, typically at purity levels above 99%, something that truly counts when formulations rely on predictable chemistry.

    In our factory, raw chlorobenzyl inputs undergo careful reactions under tightly controlled temperatures, always in closed systems to keep quality in check. Years refining our process mean our batches offer consistent physical quality—particle size, melting point, odor profile, and residue on ignition—because small variations can ripple out and disrupt a customer’s whole downstream operation. If you line up samples from various grades, you’ll spot these differences, not just in lab results but in how the alcohol disperses or integrates during mixing, dissolving, or tableting.

    Model and Specifications from Everyday Use

    Day to day, our core product centers around 2,4-Dichlorobenzyl Alcohol with a molecular weight of 191.04 g/mol and a melting range close to 70°C. For some users, that melting point matters as much as declared purity—it influences everything from solubility in common solvents, like ethanol and water, to the ease of preparation when it’s incorporated in oral antiseptics, lozenges, or topical disinfectants. For engineers in charge of scaling up batches, these details aren’t trivia; they are what distinguish a smooth process from one snarled by clumping, incomplete reactions, or separation issues.

    Our quality assurance teams pull samples from every production run. They test for residual solvents, monitor for the presence of related chlorinated benzyl compounds, and confirm the identity with both chromatographic and spectrophotometric methods. Long before a drum or bag leaves us, technicians verify that heavy metal residues fall well below recommended thresholds. Electrochemical and wet chemistry checks reveal subtle differences in the crystalline lattice, which makes a real difference in how a batch blends or dissolves. Our history with this compound gives us a collection of minor process tweaks—pressure calibrations, agitation speeds, catalyst adjustments—that have taught us what it actually takes to guarantee quality.

    Applications We’ve Supported

    Large portions of our 2,4-Dichlorobenzyl Alcohol move to customers focused on pharmaceutical and personal care products. Decades working alongside oral care manufacturers has familiarized us with their detailed technical requirements. They rely on the compound’s broad-spectrum antimicrobial properties. It disrupts microbial membranes, serving as an active ingredient in throat lozenges, mouthwashes, and sprays. Our clients need assurance that each batch carries no unexpected byproducts or contaminants, because their products must pass regulatory checks before hitting the shelves.

    Beyond just pharmaceuticals, personal care formulators use our 2,4-Dichlorobenzyl Alcohol as a preservative and antiseptic agent. In this role, clarity during dissolution and absence of suspended matter matter just as much as certified microbial activity. We’ve seen that even a tiny trace of residual solvent can become an odor complaint, especially in strongly flavored or scented finished products. Our own adjustments in final rinsing and drying have targeted these practical concerns—from our end, that means higher energy costs sometimes, but it’s evident in feedback from clients who mention odor-neutral, pure material that passes their in-house taste panels.

    Industrial settings round out the picture. Over the years, specialty solution providers have taken to our product for use in technical-grade cleaning formulas, paints, and coatings that target mold or bacteria on difficult surfaces. Each application carries its own quirks: For solvent-based cleaners, solubility and stability over a wide range of pH levels dictate the success of a batch. For antimicrobial paints, particle uniformity avoids uneven coverage, which can lead to premature failure in the field. We’ve partnered closely with these accounts, revising our filtration and micronization steps, so when the time comes to scale up from lab to production, hidden trouble in raw material quality won’t sabotage progress.

    Comparisons with Other Benzyl Derivatives

    Having made benzyl alcohols in several versions over the years, we see the real-world differences up close, especially between 2,4-Dichlorobenzyl Alcohol and more common benzyl alcohol or its mono-chlorinated relatives. Each compound offers a particular mix of antimicrobial power, solubility, odor, and chemical stability. Straight benzyl alcohol delivers low odor but often falls short on broad-spectrum antimicrobial performance. Add a chlorine or two, and the picture changes.

    Among dichlorobenzyl alcohol isomers, the 2,4-variant holds special appeal for pharma and oral care because it threads the needle between spectrum and safety. Its higher efficacy against throat pathogens and fungi—compared to the 3,5-variant or even mono-chlorinated products—explains its dominance in cough drop and sore throat products seen on store shelves. From our plant’s perspective, the route to 2,4-DCBA involves tighter reaction controls and more aggressive purification, which increases complexity and cost but results in a better final ingredient.

    We optimize for purity and consistent melting points. Less consistent producers often contribute to batch-to-batch variation that troubles end users. In our experience, medical-grade and food-grade customers are highly sensitive to changes in solubility or melting point, even as industrial buyers tolerate a wider range. Any off-odors or yellowish tint in crystalline batches usually trace back to insufficient finishing or unreacted raw material. We use our own findings to remind customers of the value in selecting suppliers who can document not just headline purity but actual handling characteristics.

    Regulatory and Safety Lessons from the Floor

    Regulatory compliance goes far beyond ticking boxes. As manufacturers, we have a front-row seat to the strictness of inspections and the weight of documentation. Regular audits of our 2,4-Dichlorobenzyl Alcohol process involve both internal quality teams and third party inspectors looking for chemical contaminants, process hazards, or incomplete tracking of batches. Over the years, we’ve had to adjust everything from on-site waste capture systems to micro-analytics that ensure no cross-contamination with other chlorinated compounds.

    End users—especially those mixing our material into food, medicinal or consumer products—count on certified cleanroom processes, DEHP-free packaging, and verified non-GMO status. It’s common to field technical audits where buyers want to see not just current SOPs but historical batch records and transport logs. We maintain this documentation not just to satisfy buyers, but because past incidents in the industry—recalled batches, contamination scares, overseas transport issues—prove the risk of skipping small process details.

    For downstream handlers, we reinforce messages about protective handling, ventilation, and the importance of avoiding repeated skin exposure, especially at the powder stage. Some customers have asked for deeper analyses on powder dusting or the impact of trace solvent residues. We’ve responded by working with material science partners to improve both the container venting and the final powder granule size. This tightens the spread of dust during handling, cuts down on workplace irritant complaints, and supports safer factory environments.

    Responding to Real-World Challenges

    Over the years, fluctuations in global supply chains, energy pricing, and environmental standards have all shaped how we make and ship 2,4-Dichlorobenzyl Alcohol. We’ve weathered raw material shortages, labor constraints, and mounting scrutiny over chemical discharges. Keeping up has demanded investments in waste water scrubbing, closed loop solvent recovery, and even on-site generation of some starting chlorobenzenes.

    We often discuss with peer manufacturers emerging challenges like microcontaminants or residual solvent limits, which change as regulatory agencies adjust their recommendations. Staying ahead of these pivots means constant review of cleaning cycles, reaction yields, and lab analysis procedures. Internal data has sometimes forced us to upgrade instrumentation or re-train staff. We trust the numbers that come from our own QC labs because they reflect what shipments actually contain, not just what should be there in theory.

    Some buyers push for “green” alternatives or bio-based derivatives. Over the last decade, we’ve seen countless proposals for more sustainable synthesis routes, but these often trade off either yield, safety, or purity. We collaborate with researchers to pilot alternatives—exploring reusable catalysts, greener solvent systems, or “waste to value” upgrades for secondary outputs. While none has matched our existing process for high-volume applications, the incremental knowledge gained supports continuous improvement in efficiency and safety.

    Supply Chain and Logistics from the Source

    Moving bulk crystals or powders with minimal degradation depends on custom packaging and careful logistics planning. In practice, humidity, temperature shocks, and static charge build-up during shipping pose real risks to product quality, not just theoretical concerns. Some years ago, after a batch to a tropical market arrived with slight clumping, we reworked our moisture barrier systems and now engineer each container—lining drums, using tamper-evident seals, and tracking temperature along export routes.

    Customers with strict shelf life requirements—especially those making lozenges or sterile oral solutions—usually need shipments in nitrogen-flushed or double-sealed bags, packed under low-light conditions. Feedback from their own stability studies has prompted us to make seemingly small tweaks in packaging film gauge, inner bag closure, and final vacuum checks. An occasional drum rejected due to exterior denting or liner puncture translates into real business loss, so we spend time with downstream staff reviewing handling methods and risk points. This investment in post-production care sets apart our deliveries, bringing both peace of mind for buyers and fewer claims from transit flaws.

    Our View on Quality: Learning from Setbacks and Successes

    Quality doesn’t just show up in a COA or certificate; it reveals itself throughout the customer’s manufacturing and testing processes. Some time ago, one of our long-established pharma clients experienced unplanned downtime when an impurity led to false positive results in their finished tablets. Our recall of that situation drove painful but necessary process reviews—adding a step for targeted impurity removal, new retention samples, and quick-response technical support. That transparency not only fixed the immediate issue but renewed trust in our whole program.

    Relentless focus on traceability and root-cause analysis underpins everything we do. We work with supply chain teams to align shipment dates, raw material lot selection, and even forecast weather-related logistic delays. It’s not paperwork for its own sake: even a minor lag in customs or a container with improper documentation can sideline a whole production schedule. These lessons have built our resilience as a manufacturer, making us flexible to customer-specific delivery and documentation requests.

    The Competitive Edge of Purpose-Built Manufacturing

    We compete with traders and resellers on a daily basis, facing buyers who sometimes see raw chemical supply as interchangeable. But our experience as an actual producer—every step from chlorination to final crystallization—lets us tune for specific needs, solve rare technical issues, and commit to ongoing process improvement. When regulatory standards shift or field complaints appear, direct manufacturing control gives us the power to investigate, adapt, and deliver new solutions.

    Some of our partners are surprised at how much technical feedback we welcome. Product managers, line supervisors, even field service workers find us eager for news about how batches performed, what dissolved or blended better, or where a storage issue led to caking or discoloration. Internal records from a decade of these comments have driven both minor and major upgrades—from adding a supplemental wash to overhauling our crystallizer design for better product uniformity. Each complaint or suggestion finds its way into process optimization programs, supplier meetings, and operator training.

    A few competitors rely on imported or toll-produced stock, but working as genuine manufacturers means we take control of safety, environmental footprint, and supply certainty. Some years, raw material volatility widens the price gap on imports, but our vertical integration cushions us against not just market swings but also regulatory surprises abroad. That steadiness, built on production experience rather than superficial cost-cutting, underlies the loyalty we see from repeat customers.

    Future Commitments to Improvement

    Looking forward, we focus our R&D and capital planning on both safety and efficiency. Each process simplification, solvent swap, or waste reduction measure undergoes in-house trials. Plant engineering teams collaborate with outside labs and process engineers; whether the target is smaller all-in-one reactors, better monitoring of minor impurities, or smarter control of thermal gradients, we build these advances into future production runs. Our drive is not just to meet the latest regulatory checklists but to anticipate changes and continue raising quality benchmarks.

    We see 2,4-Dichlorobenzyl Alcohol as more than a commodity. Its role within each customer’s pipeline matters—for the efficacy of the product, the safety of workers and end users, and the success of those businesses that depend on fail-safe chemical supply. We stand ready to adjust production to new grades, batch sizes, or regulatory requests as industries evolve. Over decades of learning, we’ve built—and continue to refine—a true partnership approach to manufacturing. That foundation means our product stands up, batch after batch, to both laboratory scrutiny and frontline use.