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2,4-Dichlorobenzotrifluoride

    • Product Name 2,4-Dichlorobenzotrifluoride
    • Alias DCBTF
    • Einecs 216-993-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    824739

    Cas Number 367-21-5
    Molecular Formula C7H3Cl2F3
    Molecular Weight 215.00 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 140-142°C
    Melting Point -23°C
    Density 1.42 g/cm3 (at 20°C)
    Solubility In Water Insoluble
    Flash Point 50°C (closed cup)
    Refractive Index 1.513 (at 20°C)
    Vapor Pressure 2.1 mmHg (at 25°C)
    Odor Aromatic
    Synonyms 2,4-DCBTF, 1,3-Dichloro-2-(trifluoromethyl)benzene
    Ec Number 206-687-9

    As an accredited 2,4-Dichlorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle, tightly sealed, with hazard labels and chemical information for 2,4-Dichlorobenzotrifluoride printed on it.
    Shipping 2,4-Dichlorobenzotrifluoride is typically shipped as a liquid in sealed, labeled containers, complying with hazardous materials regulations. It must be kept away from heat, sparks, and incompatible substances. Proper protective packaging, labeling with UN number 2233, and documentation are essential to ensure safe transport according to international and local guidelines.
    Storage 2,4-Dichlorobenzotrifluoride should be stored in a cool, dry, and well-ventilated area, away from heat sources, direct sunlight, and incompatible materials such as strong oxidizers. Keep the container tightly closed and clearly labeled. Use corrosion-resistant storage containers and avoid any conditions that could create static discharge or sparks. Store in compliance with local environmental and safety regulations.
    Application of 2,4-Dichlorobenzotrifluoride

    Applications of 2,4-Dichlorobenzotrifluoride in Industrial Manufacturing

    2,4-Dichlorobenzotrifluoride serves as a key intermediate in several industrial sectors, supporting the mass synthesis of performance chemicals through consistent supply and controlled purity. With applications rooted in specialty agrochemicals, advanced coatings, pharmaceutical intermediates, fluorinated polymers, and high-stability dyes, it supports precise formulation requirements through traceability and documented compliance, streamlining downstream processing and contributing to reliable end-product characteristics.

    1. Agrochemical Active Ingredient Synthesis

    Downstream agrochemical manufacturers utilize 2,4-Dichlorobenzotrifluoride as a primary halogenated aromatic core for synthesizing herbicide and fungicide actives. Integration into the nitration or amination stages enables the selective introduction of functional groups needed for modern crop protection agents. By sourcing stable grade material, producers reduce side-reaction contamination and lower purification demand, aligning output with registration tolerances for impurity profiles demanded by regulatory bodies.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • REACH (EC 1907/2006) Registration in the EU
    • US EPA Pesticide Registration Standards (40 CFR part 158)
    • China GB 2763 Maximum Residue Limits for Pesticides

    Typical usage ratio

    • Batch dosages range from 15% to 40% by molecular feed ratio, adjusted per desired active ingredient and process yield. Lower percentages are set when handling high-molecular-weight synthesis targets with minor substitution steps.

    Downstream process integration

    • Enters as the aromatic starter in catalytic chlorination, nitration, and amination reaction stages
    • Supports subsequent purification via crystallization or liquid extraction
    • Precursor handling requires thermally monitored charging and in-process HPLC monitoring for residual starting material

    Final product types

    • Phenoxy acid herbicides (such as dicamba and related analogues)
    • Fluorinated sulfonylurea fungicides
    • Pre-emergent weed control actives for crop protection formulations

    2. Fluorinated Polymer Monomer Production

    Producers of specialty fluorinated polymers deploy 2,4-Dichlorobenzotrifluoride as a reactive intermediate in the preparation of monomers with superior hydrophobicity and chemical resistance. Its introduction at the halogen-exchange stage defines the backbone fluorination, facilitating the polymerization routes used in advanced engineering plastics and membrane materials. Process consistency and documentation of halide content ensure uniform reactivity throughout scale-up.

    Industry compliance standards

    • ISO 9001 Quality Management System
    • UL Yellow Card for Polymeric Materials
    • ASTM D3307 Specification for PTFE Resin Materials
    • RoHS Directive (EU 2011/65/EU) for restricted substances

    Typical usage ratio

    • Introduced at 10–25% monomer feed, calibrated in relation to co-monomer ratios and required fluorination degree. Ratio adjustment based on end-use viscosity and barrier property targets.

    Downstream process integration

    • Feeds into halogen-exchange or Friedel-Crafts alkylation reactors for monomer formation
    • Monomers then undergo free-radical or condensation-type polymerizations
    • In-line FTIR monitoring establishes endpoint of halogen substitution

    Final product types

    • High-performance fluorinated polymers (such as PCTFE, PVDF derivatives)
    • Gas separation and fuel-cell membrane films
    • Corrosion-resistant industrial sealants and liners

    3. Pharmaceutical Intermediate Transformation

    API manufacturers rely on 2,4-Dichlorobenzotrifluoride for synthesis of fluorinated heterocycles and aryl cores present in targeted pharmaceutical intermediates. The controlled introduction into selective coupling reactions confers metabolic stability and desired pharmacokinetics to final APIs. All material batches require documentation of heavy metal and halide impurities, supporting GMP validation and traceability for regulatory submission.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF Monograph (as applicable per intermediate specification)
    • EDQM CEP for APIs (if required in Europe)
    • 21 CFR Part 211 (US FDA cGMP regulations)

    Typical usage ratio

    • Inserted at 5–22% of batch molar feed, based on reaction sequence. Higher input applied where aromatic substitution is the lead step in multi-step synthesis.

    Downstream process integration

    • Charged as the substrate in Suzuki or Buchwald–Hartwig coupling reactions
    • Sequentially processed through protection/deprotection regimes and oxidations
    • In-process controls monitor for residual starting material and byproduct halides

    Final product types

    • Pyridine-based pharmaceutical intermediates
    • Fluorinated benzene derivatives in anti-infective APIs
    • Specialty building blocks for cardiovascular drug synthesis

    4. Advanced Dye and Pigment Manufacturing

    Producers in the specialty dye and pigment sector incorporate 2,4-Dichlorobenzotrifluoride to introduce unique electron-withdrawing features during the synthesis of high-stability colorants. The trifluoromethyl group enhances solvent resistance and thermal durability, supporting stable shade retention in demanding textile and industrial coatings. Close control of batch color index and halide residue supports downstream application in regulated environments.

    Industry compliance standards

    • OEKO-TEX Standard 100 for textile processing
    • EN 71-3 Safety of Toys: Migration of Certain Elements
    • ISO 105-B02 Colour Fastness to Light
    • REACH Annex XVII Restriction thresholds for aromatic amines

    Typical usage ratio

    • Utilized at 8–18% of total dye formulation input, specific content varied by target chromophore class and light fastness requirement.

    Downstream process integration

    • Employed in the synthesis of azo or anthraquinone precursors via aromatic coupling and halogen exchange
    • Subject to in-process UV-Vis analysis to monitor the absorption maxima
    • Purification via column chromatography or reprecipitation ensures removal of unreacted halogenated feedstock

    Final product types

    • High-purity textile dyes for polyester blends
    • Weather-resistant pigments for industrial powder coatings
    • Light-stable inkjet and printer inks
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    Certification & Compliance
    More Introduction

    Introducing 2,4-Dichlorobenzotrifluoride: Practical Application and Real-World Performance

    A Direct Perspective from Our Manufacturing Team

    Every batch of 2,4-Dichlorobenzotrifluoride that leaves our production line reflects years of hands-on experience, careful refinement, and direct attention to the changing requirements of modern industry. This compound, often recognized as 2,4-DCBTF or 2,4-DCBTF, occupies a unique niche within the palette of halogenated aromatics. With the molecular formula C7H3Cl2F3, it stands apart for its combination of chemical stability and reactivity, balanced to support downstream synthesis for both high-value intermediates and specialty applications.

    Model and Specifications—More Than Numbers

    Our experience in scaling 2,4-DCBTF production taught us that small inconsistencies in purity or impurity profiles can throw off entire processes. For that reason, our team maintains a purity standard above 99%, tracked through GC analysis and cross-verified in-house. Moisture control is critical—water content is measured down to 0.05%—since excess water can disrupt nucleophilic substitution or metal-catalyzed steps downstream. Specific gravity usually lands in the 1.5 to 1.55 range at 25°C. Boiling point sits reliably between 182 and 184°C, giving a predictable window for distillation-based processes. Appearance matters, too; we'd rather stop a batch than let a tinted or contaminated product leave the plant. The transparency and colorless nature of the liquid isn’t just about looks—it’s the most immediate sign that a run has gone right, barring any unusual thermal decomposition or equipment leaks.

    Years of repeated syntheses revealed the most critical contaminants: ortho-isomers, unreacted monochloro precursors, acid residues, and heavy metals, especially iron and copper. These often slip through substandard processes and short-change actual users downstream. Our team keeps quantified records of these impurities per lot, not just for paperwork but to track subtle process drifts early. Titration and elemental analysis run as standard steps, alongside gas chromatography and spectroscopic checks, because spot checks alone cannot catch the small issues seen in large volume manufacturing.

    What Sets 2,4-Dichlorobenzotrifluoride Apart?

    We have produced a long list of aromatic trifluoromethyl compounds. 2,4-DCBTF brings a set of tangible differences, especially compared to 2,6-DCBTF or 3,4-DCBTF. Functional group position is not just a line-drawing difference; in practice, it changes chemical pathway selection, reaction rates, and, in some cases, byproduct formation. For example, the 2,4-dichloro arrangement creates a distinct electron distribution around the aromatic ring, which ends up making this compound more reactive toward nucleophilic aromatic substitution, particularly at the fourth position. When downstream users in agrochemicals and pharmaceuticals push for higher substitution selectivity, this is the isomer they rely on.

    Other manufacturers often tout broad buckets of “chlorobenzotrifluorides,” but smaller technical differences can make or break pilot plant performance. We’ve learned, often at our own expense, that process design relying on a generic isomer mix leads to unexpected byproducts—especially when strong nucleophiles or oxidizers are present. We focus on tight isomer control. We separate and test each fraction thoroughly. This commitment traces back to our earliest complaint calls, where a single isomer count out of specification derailed an entire lot of downstream production.

    The Practical Value of 2,4-DCBTF in Industry

    Manufacturing teams like ours think about chemical products in terms of what they deliver in the next step of the process. For 2,4-DCBTF, real impact shows up in its role as an intermediate for herbicide and insecticide production. Its molecular structure gives it the right sort of reactivity to support the Michael addition or create specialized benzotrifluoride derivatives—integral in crop protection systems across large-scale agricultural operations. This is not just theoretical. Our customers’ plants—spanning from Southeast Asia to North America—have shared feedback connecting our product’s purity profile with reduced off-gassing during late-stage chlorination, lower equipment fouling, and a measurable drop in energy use for downstream separation.

    In pharmaceutical synthesis, 2,4-DCBTF often appears in the complex stepwise creation of active ingredients or as a building block for tailored ligands in metal-mediated couplings. Its metabolic stability, driven by both the dichloro groups and the electron-withdrawing trifluoromethyl group, ensures it stays intact long enough to reach its point of conversion without decomposition. These features mark the difference between a lab-scale proof of concept and actual commercial lot synthesis, where small heat or contamination events snowball into real economic loss.

    Paint and coating manufacturers found another use for this compound as a specialty solvent and intermediate. 2,4-DCBTF dissolves a wide range of resins but resists degradation in harsh curing conditions. In one manufacturing project, a large-volume resin user switched to our consistent 2,4-DCBTF over cheaper substitutes, primarily because our product cut their lot failure rate by more than 10% and extended shelf life of their base materials during humid summer runs. This sort of practical feedback loop—where a single chemical switch tangibly improves line performance—drives our team’s commitment to reproducibility.

    End-User Success and Lessons From the Field

    Feedback from industry partners has shaped our priorities since we first scaled our reactors. Our technical support cases range from questions about scale-up conditions to requests for impurity profiles with parts-per-million detail. We do not treat these inquiries as paperwork; each is an insight into practical pain points. One resins manufacturer discovered, after months using imported 2,4-DCBTF with ambiguous origin, that their mid-batch polymerization would halt unexpectedly. Detailed analysis pointed to residual acid content and inconsistent isomer ratios as the culprit—flaws absent in our tighter batches. Sharing our step-by-step impurity tracking resolved both the customer’s immediate issue and reinforced the importance of visible, auditable product histories.

    Agrochemical companies deal in far larger scale than laboratory synthesis. A ten-ton deviation in a single raw material batch translates into weeks of downstream headaches, from plant upsets to environmental compliance headaches. Our direct customers, facing regulatory scrutiny and tight delivery timelines, pushed us to provide not just “on-spec” material but long-term supply stability. In response, we implemented real-time process analytics and historical trend tracking. These are not empty gestures; when a run veered unexpectedly due to a feed line issue, our sensors flagged a drift in byproduct ion content, allowing us to pull the batch before it reached packaging. No truck rolls out with unexplained analytics red flags. Our operational integrity depends on this level of vigilance.

    From Production Floor to Packaging: What Reliable Supply Looks Like

    Raw material sourcing plays a critical role in 2,4-DCBTF manufacturing. We source our feedstocks only from partners with proven records on aromatic substitution quality, and we routinely reject lots that show batch-to-batch drift in chlorination levels. Many believe that post-reaction purification can “fix” input variability. Experience proves otherwise. Downstream crystallization recovery, solvent washes, and vacuum distillation only mask deeper issues. Inconsistencies turn up in GC fingerprinting, showing up as subtle tails or ghost peaks. Any sign of these in our sample runs triggers a root cause analysis before further scaling.

    Packaging might seem mundane compared to large-scale chemistry, but its influence extends far beyond appearance or transport. Trace contaminants easily leach from substandard packaging materials, especially in warehouse conditions prone to heat cycling or high humidity. We made hard choices about moving away from recycled drums for 2,4-DCBTF, taking on higher upfront packaging costs. The dividend has shown up in fewer customer complaints about color shift or precipitate in stored product. These are lessons from direct customer experience, not guesses made in an air-conditioned office.

    Navigating Handling and Safety From the Factory Downstream

    Every chemical comes with safety risks. Our view of responsible manufacturing rests on sharing concrete, real-world knowledge about handling hazards and mitigation steps. Vapor exposure can irritate airways or eyes; we install regular air monitoring and personal protection for our operators. In the event of accidental spillage, we reference not only GHS standards but also our own after-action learnings. Our safety team organizes periodic drills simulating leaks and containment. Best learning never comes from paperwork alone but from seeing how product behaves in real spills.

    Shipping regulations evolve frequently. As regulations target aromatic fluorinated chemicals, we have taken steps to ensure all labeling and documentation reflect both international shipment standards and the evolving preferences of regional authorities. Consistent attention to regulatory detail shields our downstream partners from customs delays or re-export headaches—a lesson we learned the hard way through delayed shipments and border holdups years ago.

    Environmental Concerns and Our Response

    Production and downstream use of 2,4-DCBTF draw attention from environmental regulators. The reality is clear: improper disposal or accidental release can introduce halogenated byproducts into water sources or soil. Our process engineers implemented closed-loop recovery on volatile emissions and set up on-site scrubbing systems for vent gases, minimizing direct loss during production. Liquid effluent undergoes double neutralization and filtration before it ever reaches municipal treatment. Our record of regulatory inspections shows the difference: measured discharge levels consistently track below permitted thresholds.

    On the user end, we work with our clients to share best practices for storage, spill response, and eventual waste treatment. Several of our partners have adopted solvent recycling programs, re-distilling and reclaiming spent 2,4-DCBTF for reuse in closed system processes. These approaches not only reduce environmental risk but also drive down costs over the long term. Environmental performance ties directly to operational longevity—a connection every experienced manufacturer understands.

    Supporting Process Innovation in Collaboration With Our Customers

    Markets evolve, demanding improvements in synthetic routes and new applications. Over the years, we have partnered with research teams to test updated catalytic systems using 2,4-DCBTF as substrate. Close analysis of reaction yields and side-product formation has led to modified protocols that reduce hazardous waste and shrink overall energy use. One project with a fine chemicals manufacturer switched over to continuous stirred-tank reactors from older batch processing. Direct consultation on flow rates and heating cycles, tied to the specific thermal and solubility parameters of our material, resulted in efficiency gains that cut plant cycle times by almost a quarter.

    These collaborations hinge on more than transactional supply relationships. Real innovation emerges from open dialog: actual plant data, on-site troubleshooting, and willingness to adjust product runs based on pilot feedback. Our technical service team, many of whom come from the production line, bring a practical perspective to these discussions. Rather than relying solely on literature values or vendor specifications, we build our participation around actual run data.

    Distinguishing Quality: Our Real-World Benchmark

    Many chemical buyers have grown accustomed to bland promises about “reliability” and “quality assurance.” For us, the truth lies in the details—sample retentions, historical lot performance, and feedback loops with our users. We believe that real experience, not generic sales language, sets supply apart. Each ton of 2,4-DCBTF that reaches our customers carries the fingerprints of the team that produced it, the systems that purified it, and the vigilance that tracked its journey from raw material to delivered product.

    We see every customer’s unique end-use as an extension of our own work. Improvement is ongoing. We tally our share of field failures alongside our successes—treating each as data to refine the next batch. Product stability, impurity traceability, safety stewardship, and process consult all factor into what sets our material apart. As new uses for 2,4-DCBTF emerge in pharmaceuticals, electronics, and advanced coatings, we stay close to the technical trends and the changing needs behind them.

    Looking Forward: Sustained Investment in Consistency

    Long-term users know that 2,4-DCBTF, despite being a specialty intermediate, asks for more than just off-the-shelf production. Each expansion, each regulatory change, each new downstream process brings different priorities. Our approach relies on keeping both our equipment and our technical know-how up to date. We reinvest in process control, analytical instrumentation, and hands-on staff training, because even small improvements upstream prevent far larger disruptions downstream for our partners.

    Consistent supply does not come from luck. For us, it grows through sustained attention to detail and a willingness to learn from both our setbacks and our achievements. We measure our progress by the ongoing success of our customers in their own plant lines, labs, and fields. The story of 2,4-DCBTF—from starting raw material to finished specialty application—continues to unfold. We take pride in our contribution to each step along that journey and remain committed to sharing experience-backed support at every turn.