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2,4-Dichloro-6-Nitrophenol

    • Product Name 2,4-Dichloro-6-Nitrophenol
    • Alias DINOCHLOR
    • Einecs 231-799-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    996234

    Chemicalname 2,4-Dichloro-6-Nitrophenol
    Molecularformula C6H3Cl2NO3
    Molarmass 224.00 g/mol
    Casnumber 609-89-2
    Appearance Yellow solid
    Meltingpoint 156-158 °C
    Solubilityinwater Slightly soluble
    Boilingpoint Decomposes before boiling
    Density 1.74 g/cm³
    Pubchemcid 12828
    Pka 6.9 (approximate)
    Synonyms 2,4-Dichloro-6-nitro-phenol
    Smiles C1=C(C=C(C(=C1Cl)O)Cl)[N+](=O)[O-]
    Ecnumber 210-201-9
    Hazardstatements H302 (Harmful if swallowed)

    As an accredited 2,4-Dichloro-6-Nitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Sealed amber glass bottle containing 100 grams of 2,4-Dichloro-6-Nitrophenol, labeled with chemical name, purity, and hazard symbols.
    Shipping 2,4-Dichloro-6-nitrophenol should be shipped as a hazardous chemical, securely packaged in appropriate, labeled containers. Transport must comply with local, national, and international regulations for toxic and environmentally hazardous substances. Shipping documents must clearly identify the material and safety data sheets (SDS) should accompany the shipment. Handle with care to prevent leaks or spills.
    Storage 2,4-Dichloro-6-Nitrophenol should be stored in a tightly closed container, away from direct sunlight, heat, and incompatible substances such as strong oxidizers and bases. Store in a cool, dry, well-ventilated area designated for hazardous chemicals. Ensure proper labeling and prevent moisture entry. Use secondary containment to minimize spill risk, and restrict access to authorized, trained personnel.
    Application of 2,4-Dichloro-6-Nitrophenol

    Applications of 2,4-Dichloro-6-Nitrophenol in Industrial Manufacturing

    2,4-Dichloro-6-Nitrophenol serves defined technical and regulatory functions in several advanced chemical manufacturing sectors. As the original producer, we supply this material directly to established downstream partners who integrate it for its physicochemical specificity and quality-validated performance. The following sections outline the core applications where our material is a critical input, with distinct compliance frameworks, formulation details, process roles, and finished product uses.

    1. Herbicide Intermediate Synthesis

    Major crop protection manufacturers rely on 2,4-Dichloro-6-Nitrophenol as a key intermediate for synthesizing selective phenoxy herbicides, for instance, compounds targeted at broadleaf weed control in cereal and oilseed cultivation. Its unique substitution pattern enables precise downstream halogenation or nitration steps leading to high-purity herbicidal actives, under tightly regulated process controls to meet agrochemical safety and efficacy standards.

    Industry compliance standards

    • European Regulation (EC) No 1107/2009 (Plant Protection Products)
    • US EPA Pesticide Registration requirements (40 CFR Part 152)
    • ISO 9001:2015 (Quality Management for Raw Material Supply)
    • China Ministry of Agriculture GB 2763-2021 (Maximum Residue Limits for Pesticides)

    Typical usage ratio

    • In multi-step synthesis, typically 5–15% by mass relative to final herbicidal API, adjusted based on target conversion and yield optimization during the condensation and cyclization stages.

    Downstream process integration

    • Inserted during the early-stage condensation or substitution reaction as the aromatic starting material, followed by controlled oxidation, reduction, or coupling reactions under inert atmosphere in closed reactors. Downstream purification and isolation tailored to herbicide purity specifications.

    Final product types

    • Technical grade herbicide actives (e.g., phenoxyacetic acids)
    • Emulsifiable concentrate herbicide formulations
    • Wettable granular products
    • Pre-mixed crop protection solutions

    2. Dye and Pigment Manufacturing

    Specialty dye and pigment manufacturers utilize the compound as a diazo coupling component or as a critical nitroaromatic building block in synthesizing high-performance yellow and orange dyes. Its structural properties support fastness, shade, and brightness in both organic pigment and textile dye formulations, requiring precise quality assurance to conform with textile and colorant industry legislation.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (Textile Chemicals Safety)
    • EU REACH Regulation (EC) No 1907/2006 (Chemicals Registration)
    • DIN EN 71-3 (Toy Safety for Colorants)
    • GHS-CLP (EU Classification, Labelling, and Packaging)

    Typical usage ratio

    • Used at concentrations from 3–10% of total monomer/reactant feed for dye coupling reactions, depending on the target chromophore and color intensity requirements of the final pigment dispersion.

    Downstream process integration

    • Dosed into batch reactors during the diazotization or azo coupling stages, where it reacts with amine partners in aqueous or non-aqueous solution. After reaction completion, pigment isolation and milling carried out before final quality control on tone and stability.

    Final product types

    • Disperse and reactive dyes for polyester and cotton fibers
    • Organic pigments for printing inks
    • Color masterbatches
    • Textile printing pastes

    3. Photographic Chemical Synthesis

    Producers in the imaging chemicals segment use this compound as a specialty intermediate for synthesizing color developer agents or anti-fogging additives in photographic processing solutions. Its electron-withdrawing groups enable selective reactivity essential for formulating photoactive molecules, particularly in silver-halide-based systems, with batch records meeting high-purity technical specifications.

    Industry compliance standards

    • ISO 18902:2013 (Chemical Storage for Photographic Materials)
    • RoHS 2011/65/EU (Restriction of certain Hazardous Substances)
    • ANSI/NAPM IT9.11 (Imaging Processing Chemicals Quality)
    • Japanese Industrial Standards JIS K 0102 (Testing Methods for Photographic Chemicals)

    Typical usage ratio

    • Blended at 1–4% wt/wt as a functional additive, calibrated based on the molar requirement of secondary developer synthesis or as an anti-fogging component in photographic baths.

    Downstream process integration

    • Incorporated during in-situ synthesis of final developer compounds, frequently under controlled temperature and light-exclusion conditions. Final batch processed through filtration and pH adjustment before formulation with other sensitive imaging agents.

    Final product types

    • Color photographic film developers
    • Photographic bath anti-fogging solutions
    • Stabilizing agents for film and paper processing
    • High-purity imaging chemical sets

    4. Synthesis of Pharmaceutical Intermediates (Non-API Use)

    In the regulated fine chemicals sector, select manufacturers employ this nitrophenol compound as an advanced building block for non-API pharmaceutical intermediates—particularly in processes for creating aryl ethers or halogenated phenol derivatives that serve as precursors in further GMP-regulated pharmaceutical ingredient synthesis. Processing adheres to pharmaceutical input standards, monitored closely for impurity control and traceability.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • USP <1092> (Pharmaceutical Compounding – Nonsterile Preparations)
    • European Pharmacopoeia Monograph 5.10 (Impurities: Control and Qualification)
    • ISO 15378:2017 (Primary Packaging Materials for Medicinal Products)

    Typical usage ratio

    • Utilized at 2–8% of total batch mass depending on the desired halogenated phenol output and the selectivity required in multi-step synthesis for complex intermediate structures.

    Downstream process integration

    • Added as the reaction substrate in halogenation or etherification steps under GMP-compliant procedures, often in the core synthesis stage after validation of raw material identity and pre-processing under controlled environments.

    Final product types

    • Halogenated phenolic intermediates (non-API)
    • Aryl ether intermediates for pharmaceutical routes
    • Fine chemical building blocks for subsequent active ingredient synthesis
    • Validated non-API intermediates for further GMP production
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    Certification & Compliance
    More Introduction

    2,4-Dichloro-6-Nitrophenol: A Manufacturer’s Introduction

    A Closer Look at Crafting 2,4-Dichloro-6-Nitrophenol

    Most industries rely on products they don’t always see with their own eyes. Deep in chemical production lines, every gram must rise to the challenge customers set for purity and consistency. 2,4-Dichloro-6-Nitrophenol stands as a specialty intermediate, finding its role in a range of synthesis processes because it delivers specific performance properties, especially as a nitroaromatic building block. From the start, our motivation has always come from real-world demands—delivering 2,4-Dichloro-6-Nitrophenol in a way that meets the needs of downstream chemists who care about reliability batch after batch.

    Alone in a controlled reactor, we focus on target reactions that avoid contamination at every stage. Strict handling and continuous monitoring keep everything in line—never cutting steps, not just to satisfy regulatory checks, but because every shortcut taken today turns into quality issues tomorrow. Our technical team’s background in classic electrophilic aromatic substitution supports every kilogram we turn out. Real skills, practiced over years, matter more than textbook theory, so we draw from hands-on training and knowledge shared across generations of chemists and production workers in our plant.

    Model and Specifications in Practice

    We synthesize 2,4-Dichloro-6-Nitrophenol as a pale yellow solid, which reflects a purity level exceeding 98 percent by HPLC. Our focus isn't just about hitting numbers—it’s about making sure that appearance, melting point, and performance indicators all line up, because that is what customers check. Careless manufacturing leads to problems in downstream syntheses; so any off-odor, odd color, or inconsistent melting point instantly raises flags internally. Chlorine content, nitro group orientation, and low residue on ignition must stand up to scrutiny.

    Whenever batches leave our plant, we pull random samples for internal and third-party analysis. Any impurity peak above trace quantities raises questions. By handling all reactions ourselves, from chlorination to nitration, and not farming stages out to tollers, we keep control over quality at every link in the process. This safeguards reproducibility, which is what matters most in real-world synthesis—anything less drives up costs due to repeated product failures.

    Why Application Context Tells the Whole Story

    End-users have taught us that nothing about this intermediate should be generic. In dye manufacture, even slight changes in the placement of chloro or nitro groups change shade and fastness properties. In agricultural product synthesis, incorrect ratios lead to massive regulatory headaches and lost batches on the farm. It’s not rare for us to get calls from formulation chemists seeking clarifications about compatibility with other aromatic blocks, and we are always ready to unpack key differences—because we’ve run those same trials ourselves in our application labs before scaling up.

    2,4-Dichloro-6-Nitrophenol’s electron-withdrawing properties from both chlorine and nitro groups set it apart. Some customers try to substitute with mono-chlorinated or di-nitro phenols for cost savings; in repeat tests, these switches never deliver equivalent reactivity for nucleophilic aromatic substitutions. Our experience shows that synthetic outcomes depend on precise electron density around the aromatic ring, and that is achieved only with the double chlorine and the specific placement of the nitro group at the 6-position. Our approach is to walk customers through these numbers, show example spectra, and break down what to expect. Education is as vital as the product itself.

    The Reality of Handling and Compliance

    Raw material procurement isn’t just about finding the lowest price. Our procurement specialists source chlorinated benzenes and nitrating agents from vetted suppliers, and document every shipment to support both customer and authority questions. Audit trails stretch back years. The team has seen regulators carry out unannounced site visits and undertake rigorous sampling practices, so we design our procedures for transparency. It’s a necessity born from experience, not just paperwork for its own sake.

    On the shop floor, environmental safety drives us more than any compliance manual ever could. Fumes and reaction byproducts require careful handling and closed systems. Continuous air monitoring, real-time spill response, and containment protocols all reflect lessons etched by old accidents or close calls in this industry. Our people wear personal monitoring devices; nothing sharpens diligence like a near-miss. Every newcomer learns from veterans how to spot risks, not just follow instructions, which shields both product and personnel.

    Differences That Matter in the Field

    All 2,4-Dichloro-6-Nitrophenol is not created equal. Variants with lower purity drop out as brown or gray solids, and performance drops sharply for pigment manufacturers and active ingredient developers. Even minor isomer contamination throws off reaction kinetics, based on data directly from our customer partners. We have worked with teams who spent weeks de-bugging synthesis routines, all because their input batches didn’t match our specification for isomer ratios. In short, chasing low-cost alternatives leads to more wasted time and money down the road.

    Customers often share tales of downstream blockages: sticky residues in reaction vessels, unwanted tars, or shift in yield curves over what seem like trifling variances. These link back to the way this intermediate is made. End-users have asked for tighter controls on melting ranges and spectral markers, which we deliver by constantly re-investing in analytical tools like GC-MS, FTIR, and high-sensitivity HPLC.

    Our own trials reinforce these points. In comparing several suppliers worldwide, we’ve seen responses from end-users—ranging from polymer chemists to organic intermediates formulators—who struggled with batch-to-batch inconsistencies leading to re-qualification needs, recalls, or outright rejection. Our technical services team regularly fields requests for additional support, because not every manufacturer in the market actually stands behind their product data.

    Hands-On Solutions for Real-World Problems

    Waste generation represents a significant concern in both our own processes and those of our clients. Over years of operation, we have designed our reactors and scrubbing systems to minimize both spent acid and chlorinated waste streams. Customers pay attention to waste load because regulatory thresholds tighten every year—and fines, even for trace emissions, damage both reputation and bottom lines. Design tweaks like baffle placement and precision temperature control cut down side-reaction products at the root.

    Every conversation with a technical buyer or process engineer quickly turns to reproducibility. The push for green chemistry drives us to look for more selective catalysts and ways to cut down on raw material excess, not just for cost, but because waste disposal eats away at the margin as much as lower conversion rates. Developing a more selective process for the aromatic substitution that leads to 2,4-Dichloro-6-Nitrophenol took years, but the reduction in byproducts and tighter melting point ranges earned trust from both new and legacy users.

    The Role of Feedback in Continuous Improvement

    We make it a habit to ask users for feedback after each shipment. Labs and plants working with our material share performance data, and we track outcomes such as reaction speed, byproduct formation, and isolated yield. After noticing a recurring theme of difficulty in subsequent coupling reactions, we tweaked our drying and packaging steps to cut residual moisture below 0.2 percent. Simple changes, rooted in direct feedback, push us to higher standards.

    Some partners share their own in-house spectra and side-by-side results. Rather than hide behind our own figures, we join their operators in the lab, walk through results, and compare notes—many times identifying factors like shelf life, container interaction, or handling procedures impacting final results. This collaboration grows mutual understanding and brings forth practical tweaks no outside consultant could propose.

    Practical advice rarely comes from lofty principle. Instead, a cycle of action and review makes us better at catching outliers before they ship. Our quality group finds its motivation in solving specific issues from the customer’s site rather than mere theoretical targets. Combining this hands-on approach with routine analytics builds the backbone of trustworthy supply.

    Safety Built Into Each Step

    Those who handle 2,4-Dichloro-6-Nitrophenol up close keep an eye on real exposure—not just paperwork levels. We have learned to design containers and liners to keep both product and workers safe from dust and accidental contact. High-visibility labeling and clear procedural handouts go a long way, but direct, on-the-line training gives workers the confidence to spot and handle any incident. By refining handling and packaging, we have reduced minor incidents and improved satisfaction on receiving docks.

    Our on-site first responders train with scenarios based on problems we've encountered, not just simulated events. Over decades, we have collected the sort of practical knowledge that comes only from hundreds of shifts, thousands of batches, and open communication with our workforce. Improvements in workflow—like double-sealed transfer ports and investment in local ventilation—grew directly from field experience rather than top-down directives.

    Supporting the Analyst’s Job

    Many end-users depend on robust analytical packages for inbound quality checks. To support transparent and rapid acceptance, we provide full spectral libraries (UV, IR, NMR) with each delivery. Over time, some customers found subtle peaks related to degradation when 2,4-Dichloro-6-Nitrophenol is stored improperly; we use these observations to update storage recommendations and align packaging with real-life warehouse conditions.

    Feedback from analysis teams helped us refine our documentation, focusing on reporting what matters on the bench. Tech sheets now list impurity profiles and matching chromatograms, not just minimum purity levels, reflecting questions and requests that field chemists raised. We keep a standing invitation: any lab can share anomalies or unexpected behavior, and our team will look into it with priority and openness.

    How Shipment and Storage Affect Performance

    A lesson we learned early: packaging matters just as much as in-plant quality. Humidity, temperature swings, and mechanical jostling during transit all impact 2,4-Dichloro-6-Nitrophenol's stability. After a few cases of caking and partial clumping seen in customer warehouses, we swapped over to heavy barrier liners and inert gas flush. Making investments in transit monitoring and reinforced drums produced immediate returns—goods arrived in condition fit for direct use.

    An overlooked challenge often lies in thermal history. Extended freight journeys exposed to heat or sunlight sometimes led to off-color or altered melting points, putting the burden back on receivers. Fixes like light-blocking outer wraps, temperature loggers, and "first-in, first-out" shelf policies stem from these lessons. Proactive checks at transfer points make a measurable difference—finding root cause before it gets to a customer’s lab. This kind of responsiveness begins in logistics planning, not at a desk.

    Connecting Directly With End Uses

    Getting input from users at each point in the chain—be they formulation, research, or production chemists—anchors each improvement. In pigments and polymers, our product supports colorfastness and stability in extreme conditions. Finer points, like residue levels and leaching resistance, came directly out of requests from material scientists pushing their own formulas to the edge of performance. We engage with them to understand what marks a deal-breaker: is it film clarity, is it hue retention, is it processing time? Our bench trials aim for more than box checking, seeking out the edge conditions real formulations face.

    Pharmaceutical R&D users bring more stringent controls. Here, trace impurities take on greater significance. In those cases, our product release specifications not only match regulatory needs but incorporate extra steps based on first-hand experience with cleaning reactions and stringent residual solvent controls. Our documentation does not just echo established standards but comes directly from what our partners expect and, sometimes, from solutions jointly developed in their labs and ours.

    Innovation and Adaptability in Sourcing

    As global chemical sourcing continues evolving, disruptions in basic raw materials—chlorobenzenes, nitric acid, process catalysts—challenge schedules and cost estimates. Our sourcing teams built relationships with verified partners and invested in buffer stock, so we could keep supply steady during hiccups; a lesson learned from previous global crises. We neither chase the cheapest option nor chase trends, but rather stick with reliability and open communication with suppliers who have proven themselves dependable.

    We meet each sourcing crisis with a thoughtful review of whether new suppliers can match our QC standards before onboarding. Raw material qualification involves running pilot-scale syntheses and repeating analytic checks—cutting corners only leads to worse long-term headaches. We keep an open mind but hold the line on critical parameters of purity and flow—shared reality over wishful thinking.

    Tuning Manufacturing to Customer Needs

    One-size-fits-all rarely hits the mark. Over time, specific sectors requested modifications—say, extra-fine particle size for pigment dispersion or higher purity for pharma applications. We collaborate on custom specs, then ramp up with small pilot runs, gathering real data before scaling. Adjustments range from minor tweaks in filtration technique to major reactor redesigns. Every customization is backed by a chain of documentation and analytical evidence.

    We noticed requests building for lower dust formulations and improved flowability, especially in automated handling systems. By working with equipment suppliers and user feedback, we invested in upstream drying and precise sieving, reducing fines below measurable limits. Such process improvements deliver value not through promises but repeatable, positive experience—users see cleaner, easier, and more reliable handling in their facilities.

    Trusted Over The Long Run

    End-users return for material they know will meet their requirements, not for the flashiest packaging or lowest introductory price. Trust is a currency built only through performance. Over years, our partners see that dedicated ownership of production, strict QC, and willingness to adapt beat any generic formula. Each improvement feeds back into the next cycle, and every batch heading for dispatch reflects the lessons of all that came before.

    Our commitment drives from an honest evaluation: what would we expect if we stood in the customer’s shoes? Not every company puts that philosophy into action; we let our reputation evolve naturally through field results, open dialogue, and accountability for each lot. Technical support doesn’t just mean sending data—it means sharing in your problems, walking through solutions together, and keeping supply flowing as reliably as day follows night.

    Summary: The Value of Manufacturer-Driven Insight

    Every experience on the production floor, every technical call from a partner, and every adjustment made for real-world issues has sharpened our understanding of 2,4-Dichloro-6-Nitrophenol. Our track record reflects a clear commitment to practical outcomes rather than empty marketing. By learning directly from users and applying this hands-on expertise, each new batch improves in line with rising expectations and evolving standards. That feedback cycle is what makes the difference between just selling a chemical versus standing alongside you as a true producer partner.