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HS Code |
114969 |
| Chemicalname | 2,4-Dichloro-3-Nitrophenol |
| Casnumber | 609-89-2 |
| Molecularformula | C6H3Cl2NO3 |
| Molecularweight | 208.00 g/mol |
| Appearance | Yellow crystalline solid |
| Meltingpoint | 144-146 °C |
| Solubilityinwater | Slightly soluble |
| Density | 1.70 g/cm3 (approximate) |
| Pka | 6.8 (phenolic proton) |
| Synonyms | 2,4-Dichloro-3-nitro-phenol |
| Smiles | C1=C(C(=C(C(=C1Cl)Cl)[N+](=O)[O-])O) |
| Inchi | InChI=1S/C6H3Cl2NO3/c7-3-1-4(8)6(10)5(2-3)9(11)12/h1-2,10H |
| Ecnumber | 210-207-8 |
As an accredited 2,4-Dichloro-3-Nitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A sturdy amber glass bottle containing 100 grams of 2,4-Dichloro-3-Nitrophenol, sealed with a screw cap and hazard labeling. |
| Shipping | 2,4-Dichloro-3-Nitrophenol should be shipped in accordance with hazardous material regulations. It must be securely packaged in airtight, chemical-resistant containers, cushioned against breakage, and labeled with appropriate hazard symbols. Transport is permitted only by authorized carriers, with documentation including safety data sheets to ensure safe and compliant handling and delivery. |
| Storage | 2,4-Dichloro-3-nitrophenol should be stored in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and properly labeled. Segregate from incompatible materials such as strong acids, bases, and oxidizing agents. Use appropriate chemical-resistant containers and ensure spill containment to prevent environmental contamination. |
Applications of 2,4-Dichloro-3-Nitrophenol in Industrial Manufacturing2,4-Dichloro-3-Nitrophenol serves as a key functional intermediate in several chemical sectors. Our factory supplies this compound globally to downstream manufacturers with strict process and quality demands. We outline major industrial applications below, each highlighting real regulatory, formulation, and manufacturing requirements. 1. Agrochemical Intermediate – Herbicide FormulationDownstream agrochemical companies use this material as a building block in synthesizing selective herbicide products. The compound functions as a crucial aryl substitute in multi-step organic syntheses, enabling efficient production of nitroaromatic-based actives widely used in post-emergence applications across cereal, rice, and maize crops. Manufacturing teams maintain strict process control over impurity profiles and chiral intermediates to meet international registration standards. Integration into the production lines usually follows the primary batch nitroation stage and precedes coupling or condensation steps. End products range from water-dispersible granules to emulsifiable concentrates, distributed for regulated agricultural use. Industry compliance standards
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2. Pharmaceutical Intermediate – API SynthesisLeading pharmaceutical manufacturers purchase this nitrophenolic compound as an advanced intermediate in active pharmaceutical ingredient (API) synthesis pipelines, particularly in development of nitroaromatic backbone APIs for antibacterial or anti-inflammatory agents. Process engineers require consistent lot purity and trace metal specification to avoid downstream product variability and failed batch releases. The compound is dosed at controlled ratios during aromatic ring activation and halogen exchange stages. Downstream, it enables scalable multistep syntheses under GMP conditions. Final APIs undergo rigorous medical and regulatory audit, forming the basis of finished drugs supplied globally. Industry compliance standards
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3. Dye and Pigment Manufacturing – Azo Dye ProductionSpecialty dyes and pigment plants apply 2,4-dichloro-3-nitrophenol as a coupling component for azo dye synthesis. This aromatic substrate reacts efficiently in diazotization and coupling stages, imparting color stability and fastness to synthetic fibers and specialized plastics. Manufacturing operations control reaction conditions, including pH and temperature, to yield high-purity pigments that meet international textile and plastics standards. Product engineers adjust input ratios depending on the brightness and UV resistance demanded by end customers in the coatings, plastics, and textile value chains. Material typically enters the process in the coupling phase, ensuring consistent chromophore generation. Industry compliance standards
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4. Fine Chemical – Photographic Chemical SynthesisProducers of fine chemical reagents integrate this compound as a precursor in synthesis of specific sensitizers and color couplers for photographic materials. Precision control over substituent position and purity is vital to achieving consistent light sensitivity and coloration properties in finished products such as film emulsions and specialty imaging plates. The raw material enters after initial halogenation and nitration phases, participating in ring-modification reactions that define the spectral response of high-grade photographic materials. Quality assurance measures at this stage determine downstream product suitability for international analogue imaging processes. Industry compliance standards
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Producing 2,4-Dichloro-3-Nitrophenol over the years has taught us the value of being hands-on with every step in a chemical’s journey. We handle this phenol derivative in-house, keeping quality at the center. Ours arrives as a yellow crystalline product. Experienced hands make sure the batch remains free of characteristic impurities, as clarity at this stage influences downstream reactions in specialty chemical synthesis.
Years of direct work with chlorinated nitrophenols have shown the subtle ways in which small changes in the synthesis process can influence purity. From raw material sourcing to recrystallization methods, our focus lands on repeatable results and chemical stability. The typical melting point reaches about 138-142°C, and our own GC and HPLC checks regularly confirm a purity above 99%. Granule size and density pass through regular inspection, so handling remains predictable from start to finish.
Colleagues in pesticide and dye intermediates research favor 2,4-Dichloro-3-Nitrophenol for making specific agrochemical molecules, particularly where precise electron densities shape the chemistry. Its double chlorine substitution adds reactivity control and boosts selectivity, which translates directly to higher process yields and cleaner downstream profiles. Our own plant experience reflects this: production lines run smoother when the intermediate’s structure matches specification batch after batch.
This chemical works as a building block for crafting more tailored phenolic derivatives and certain azo dyes. Plants working on veterinary pharmaceutical intermediates or fungicide precursors often look for the reactivity balance this molecule brings. Compared to mono-chlorinated or unsubstituted nitrophenols, we’ve seen improved ease of nitration and cleaner product separation. Our on-site data shows those working with diazo coupling reactions get sharper conversions using this specific arrangement of chlorine and nitro groups.
We code our 2,4-Dichloro-3-Nitrophenol as DCNP-243N, aligning it across synthesis lines for easy tracking. On a practical level, finished product appears as a free-flowing, fine yellow crystalline solid. Batch purity averages consistently above 99%, with no discernable dust levels from proper drying and milling methods. We supply this in moisture-proof, double-layer bags to keep it stable, and water content stays under 0.3% in our outgoing lots.
Beyond purity, experience highlights another spec often missed by distributors: color index consistency. Users have pushed for reliable color because trace byproducts often hint at deeper quality issues. Our approach keeps the yellow within a narrow range, drawing regular feedback from clients who rely on visual cues during mixing and reaction steps.
We subject each output batch to a full round of wet chemistry and instrumental checks. Our teams test solubility in organic solvents, monitor titration values, and spot-check for residual halides. It’s standard for us to share recent production data, not just “typical” values. Over time, this transparency has improved trust and outcomes on both sides of the factory gate.
Years of hands-on comparison work with 2,4-Dichlorophenol, 2,4-Dinitrophenol, and 4-Chloro-3-Nitrophenol shed light on the unique role our product fills. For clients who have tried swapping in say, monochlorinated nitrophenols, our feedback proves that the balance of reactivity and selectivity gets lost quickly. These alternates either progress too slowly in cyclization steps or throw off too many tars and polymeric byproducts in condensation reactions.
We see sharper nitro substitutions and more efficient azo couplings with 2,4-Dichloro-3-Nitrophenol. It doesn’t behave like a basic chlorinated intermediate. The ortho and para chlorines shape the electron field and allow for more controlled subsequent transformations. This has made a visible difference for customers optimizing batch yields or managing powder dusting and color drift under different mixing conditions.
Compared to dinitrophenols, our product’s solubility presents fewer challenges in post-reaction separation. Dinitro compounds tend to require rugged extraction setups, introducing cost and time drains. By supplying a mono-nitro and di-chloro, we built a solution for plants preferring streamlined, predictable processing. Several agricultural chemistry developers in our network report measurable improvements in both throughput and end-use chemical stability by moving away from single-substituent phenols.
No catalog or datasheet replaces the practical moments spent on the plant floor. Direct involvement in kilo and ton-scale runs makes it clear that moisture control during recrystallization and drying cycles holds real importance. Early batches prone to minor caking and inconsistent pourability cleared up when we overhauled our solvent choices and rotary evaporation routines.
Solvent residue also drew our attention. High boiling point residuals led to unstable storage and tough blending down the line. With rigorous solvent switching and extended vacuum drying, we now keep total residual solvents to a fraction of regulatory limits and confirm it using in-house GC screening, not just relying on external labs.
Operators reported that dusting and static could cause headaches during manual weighing. To fix this, we modified particle sizing parameters and dialed in humidity control to keep the material easy to handle. Feedback from downstream blenders and formulators pointed out that regular re-testing for drying loss supported long-term quality, so we made that a documented step in the outbound check.
Chemists beyond our company described how 2,4-Dichloro-3-Nitrophenol’s stability in basic conditions supports layered reaction sequences. Colorants and sensitizers developed from this base often display less batch-to-batch drift. Production managers in dye and pigment lines share that granule uniformity means consistent dispersion, which reduces scrap rates and improves reproducibility.
One agrochemical firm worked closely with us to troubleshoot filtration bottlenecks. We adapted our crystal washing steps and switched finishing solvents. These minor but targeted tweaks reduced their filtration times by over 40%.
Direct conversations and application visits have given us insights not available through any outside reports. Some fungicide developers in central Europe have enjoyed production cost reductions due to our product’s straightforward crystallization profile compared to imported alternatives with undesirable byproducts.
Real risk management starts long before a drum leaves the warehouse. We paid close attention to occupational guidelines and made changes to our plant layout. Process operators use closed transfer setups, which cut down airborne exposure and limit spills.
All production staff receive hands-on training sessions. Direct observation showed that simple practices, like using contained blenders and anti-static mats, reduce risk more than elaborate technical solutions. We keep full personal protective equipment on hand and maintain local exhaust ventilation right by the powder filling stations.
Our safety protocols go beyond finished goods. Raw material storage and reaction vessel cleaning both get detailed schedules. On-site incident reviews raised early awareness, leading us to code all intermediate containers and test rinse wastes for trace chlorinated organics. This helps manage downstream environmental treatment needs, making for smoother audits and a safer workplace.
Experience in this field puts daily focus on both regulatory expectations and community well-being. Long before broader moves for green chemistry became widespread, we began improving our waste neutralization routines and water management. Part of each new batch’s journey features routine effluent testing for traces of phenols and chlorinated derivatives, and we implemented permanent collection and treatment for all spent solvents rather than venting or uncontrolled discharge.
We took the step to certify our plant operations not just for ISO standards but through ongoing third-party reviews. Supporting data from our water and air discharge streams shows meaningful progress in controlling trace releases compared to early records. These in-house gains mean supply partners and local regulatory agencies receive reliable, ongoing updates on site-by-site conditions.
Final product packaging fits the needs of hazardous logistics, using double-barrier linings and tamper-evident seals. Shippers receive complete lot analysis and a paper trail on solvent residue levels, producing a clear material history and full traceability. We found this open approach cut down on delays at port checks and border transfers, getting product to customers without the headaches and silent surprises typical from less transparent sourcing.
Direct control over both raw material selection and production workflow keeps the 2,4-Dichloro-3-Nitrophenol output on spec. In cases where partners reported issues, our technical service team worked side by side on trial runs—sometimes tweaking pH, solvent use, or temperature settings to resolve bottlenecks. We offer plant visits and remote audits, drawing on our own production records to troubleshoot, not conjecture.
A benefit of our approach is keeping a practical eye on raw material sources. Instead of relying on bulk spot purchases, we foster direct links with main feedstock suppliers, running our own impurity sorption and compatibility screening. This hands-on vetting paid dividends during recent global supply chain disruptions, where we kept batch release schedules while other producers backordered or cut blends with off-spec substitutes.
Some rural chemical operators messaged us about unexpected color drifts during heat-sensitive synthesis. Our lab staff reviewed sample back-codes, re-ran crystallization, and pinpointed residual impurity loads due to high storage humidity. By shifting to nitrogen-sealed storage and quick-port bins, those customers saw their finished products return to previous levels of appearance and function.
The field experience over decades makes it obvious that robust, consistent back-support from the manufacturing site means more than just paperwork compliance. Real process value gets built one cleaned reactor, stable drum, and on-time shipment at a time. Over the years, feedback from regular customers and quality auditors alike helped shape both small daily routines and major upgrades.
Running a chemical manufacturing line places us in a living network of industry feedback and shared growth. Practical involvement in each step, from receiving raw materials to shipping finished goods, shapes both tradition and innovation. Customers, plant managers, technical directors and lab leads all influence the next iteration of the process.
A recent collaboration with a Japanese pigment manufacturer involved jointly testing new purification steps, and together, we reduced residual aromatic solvent traces to nearly undetectable levels. These advances only happen at the source, where every tweak can be measured, confirmed, and fed back to the next cycle. That’s why our whole plant culture remains open to change, as practices honed in one region can often improve outcomes across distant applications.
Serving the specialty chemicals community for over two decades comes with challenges and rewards. As technology shifts and environmental stewardship rises in importance, we see firsthand how proactive communication and process discipline keep both quality and relationships strong.
Producing 2,4-Dichloro-3-Nitrophenol on a real-world scale fosters an appreciation for the direct effect manufacturing choices have on performance, safety, and end-use promise. Our plant’s feedback-driven approach means buyers receive more than just specification sheets—they get products grounded in field-tested reliability. Industry and community benefit when supply partners use proven routines, robust communication, and a willingness to adapt.
Our daily work keeping 2,4-Dichloro-3-Nitrophenol consistent and supportive of modern application needs reflects more than tradition. The outcome is the reliable supply that helps unlock chemical progress—from the control of dye shades to the efficiency of new agrochemicals, all shaped by direct manufacturing experience. Those seeking real value find it in close-knitted expertise and a relentless pursuit of betterment, batch after batch.