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HS Code |
554083 |
| Product Name | 2,4-Dichloro-3-Fluoronitrobenzene |
| Cas Number | 1435-48-9 |
| Molecular Formula | C6H2Cl2FNO2 |
| Molecular Weight | 209.99 g/mol |
| Appearance | Yellow to light brown crystalline solid |
| Boiling Point | 274-275 °C |
| Melting Point | 48-52 °C |
| Density | 1.65 g/cm³ |
| Solubility | Slightly soluble in water |
| Purity | Typically ≥98% |
| Smiles | O=[N+](O-)C1=CC(Cl)=C(F)C(Cl)=C1 |
| Inchi | InChI=1S/C6H2Cl2FNO2/c7-3-1-4(8)6(10(12)13)2-5(3)9/h1-2H |
As an accredited 2,4-Dichloro-3-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g amber glass bottle with tight-sealing cap, labeled "2,4-Dichloro-3-Fluoronitrobenzene," hazard pictograms, and safety handling instructions. |
| Shipping | 2,4-Dichloro-3-Fluoronitrobenzene is shipped in tightly sealed containers, compliant with local and international chemical transport regulations. It should be stored in a cool, dry, well-ventilated area, away from incompatible substances. The shipping package must display appropriate hazard labels, as the substance may be harmful if inhaled, ingested, or in contact with skin. |
| Storage | 2,4-Dichloro-3-Fluoronitrobenzene should be stored in a tightly closed, clearly labeled container in a cool, dry, well-ventilated area away from incompatible substances such as bases, strong oxidizers, and reducing agents. Keep away from heat, direct sunlight, and sources of ignition. Use appropriate chemical storage cabinets and ensure that all containers are resistant to corrosion by the chemical. |
Applications of 2,4-Dichloro-3-Fluoronitrobenzene in Industrial ManufacturingOur vertically integrated production of 2,4-Dichloro-3-Fluoronitrobenzene supports specialized downstream industries requiring intermediates for advanced chemical syntheses. We supply this raw material to contract manufacturers, formulation plants, and QC-driven end-users who demand consistent purity and traceable supply for strict industrial use cases. Below, we detail primary application segments recognized for dependably using this intermediate in regulated processes, with direct reference to compliance standards, practical dosage benchmarks, process flow, and output product formats. 1. Pharmaceutical Intermediate Synthesis (Agrochemicals and Active Pharmaceutical Ingredients)Manufacturers in pharmaceutical and crop protection sectors incorporate our product as a key intermediate for selective fluorinated and chlorinated heterocycle synthesis, including for sulfonamide antibiotics and certain herbicide actives. The chemical enters multi-stage routes to produce compounds requiring precise halogenation patterns, meeting regulatory constraints for trace impurities and stability. Customers deploy this raw material where electron-withdrawing groups are fundamental in optimizing bioactivity for final APIs or technical actives. Industry compliance standards
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2. Agrochemical Synthesis for Herbicide IntermediatesSpecialty agrochemical producers rely on consistent supplies of this halogenated nitrobenzene for the controlled synthesis of pre-emergent and selective herbicide intermediate compounds. Its unique substitution profile directly supports downstream halogen exchange and nitro group reduction, both steps central to the production of proprietary active moieties. Application protocols ensure that this raw material aligns with regulations for pesticide intermediates, prioritizing batch-to-batch homogeneity and trace impurity registration. Industry compliance standards
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3. Fluorinated Aromatic Compound Production for Electronics ChemicalsProducers of fluorinated aromatic compounds for electronics integrate this fluoronitrobenzene in the manufacture of advanced, high-purity intermediates for liquid crystal and OLED materials. The material’s defined halogenation supports downstream coupling and reduction reactions needed for the development of rigid-rod structures and specialty display chemicals. Trace metal and moisture levels are controlled to meet electronic-grade standards, reflecting the critical need for defect-free raw materials in optoelectronic applications. Industry compliance standards
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4. API Intermediate Supply for Veterinary PharmaceuticalsVeterinary pharmaceutical synthesis routes incorporate this compound in the assembly of fluorinated and chlorinated aromatic intermediates, critical to developing active substances in parasiticide and antimicrobial veterinary preparations. The material’s impurity profile and documentation meet regulatory submission requirements for veterinary medicines, allowing for integration into compliant supply chains supporting global producers. Lot-specific characterization ensures conformity for registration purposes. Industry compliance standards
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5. Fine Chemical Building Block for Specialty Dyes & PigmentsManufacturers producing specialty dyes and effect pigments for plastics, coatings, and technical textiles use this chloro-fluoro-nitrobenzene as a foundational building block. The chemical’s reactivity enables controlled halogen or nitro substitutions during azo coupling and subsequent pigment stabilization steps. Adherence to colorant industry safety and registration protocols is maintained throughout supply and documentation, with QC focused on minimizing byproduct coloration and residual halides important for high-purity dye outputs. Industry compliance standards
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Producing 2,4-Dichloro-3-Fluoronitrobenzene offers a unique perspective on the intersection of chemistry knowledge, manufacturing expertise, and industrial demand. As a chemical producer, every step involves decisions shaped by years of real plant experience. Here, in our facility, creating this specialized compound requires rigorous control—not just at the reactor, but through every stage until the finished material leaves our loading bay.
This compound, commonly known by its CAS number 393-53-1, stands out for several reasons. The structure features two chlorines at positions 2 and 4, a fluorine at position 3, and a nitro group. This particular arrangement catches attention because each atom brings a distinctive trait in downstream chemistry. The electron-withdrawing nitro group, combined with halogen substitution, lays a stable foundation for further synthesis.
Chemical manufacturing comes down to purity and predictability. 2,4-Dichloro-3-Fluoronitrobenzene must meet demanding purity standards to ensure tight yields in later processes. In our plant, finished product regularly reaches a purity of at least 99%. Lesser fractions get removed by repeated distillation and recrystallization. Not all competitors manage the same yield or control over trace byproducts, but continuous improvement remains a priority here. Our years in production have taught us that purity and batch consistency matter much more than flashy product data sheets.
Visually, the compound presents as a yellow-to-pale solid with a firm crystalline nature. Handling in larger quantities benefits from stable melting properties and low volatility under standard industrial conditions. We monitor for moisture pickup and decomposition with every batch pulled off the line, especially during humid months. Our team re-invests in material handling infrastructure, adding improved hoppers and automated controls, all to unlock safer and cleaner movement of material.
Packaged for practical use, our drums and lined containers reduce risk of contamination or material loss. Employee training extends right from lab chemists to the loading dock, woven into operations since minor oversights can snowball in specialty chemistry.
Having produced this compound for close to a decade, we have watched where it goes and how it transforms. Its chief use comes as a building block in agrochemical synthesis. The placement of chlorine and fluorine atoms gives downstream chemists a platform for selective transformations. In real-world projects, this molecule lets partners construct herbicides and fungicides designed to target pests without damaging crops. Feedback from formulators frequently praises the reliability of our product, since inconsistent raw material can compromise formulation work and push back launches.
Beyond agrochemicals, pharmaceutical synthesis pulls volumes each year. Medicinal chemists value electron-deficient aromatics for creating unique coupling partners. The meta fluorine offers positional versatility, a detail that sounds small until you work day-in and day-out synthesizing difficult precursors. Reaction yields on pilot-scale samples routinely outperform those from lower-grade sources, cutting waste for partners who must stretch every kilogram.
Some customers run exploratory research with niche materials. Recently, we supported a team exploring new energy storage materials using halogenated aromatics. Our direct working relationship with end-users allows us to tweak specifications or adapt packaging to non-standard equipment. No two projects ever look quite the same, and being the producer gives us meaningful flexibility. Having the deep knowledge of process adjustments—without several layers of intermediaries—lets us help partners get what they really need instead of “off the shelf” compromises.
Many chemicals share close relatives, and 2,4-Dichloro-3-Fluoronitrobenzene has its share of cousins in the halonitrobenzene world. Comparisons get made to variants lacking a fluorine or shifting the nitro group. In routine synthesis, tiny changes in substitution often ripple downstream. For instance, switching fluorine for hydrogen at position 3 alters both reactivity and solubility. Experienced chemists spot this in reaction sequence planning: The resulting intermediates behave differently during cross-coupling or nucleophilic aromatic substitution.
The presence of chlorine at both ortho and para positions gives this compound a unique pattern of electron distribution. Fluorine, much more electronegative, adds another layer of control, which becomes important during conditions that demand selectivity in metal catalyst systems. Having worked with other isomers, we see marked differences in melting ranges, color retention in storage, and behavior in the reactor itself. Some competitors offer isomer mixes or relaxed specs, which may fit bulk intermediates, but our choice of this specific isomer stems from repeated process feedback and real-world success stories. We don’t just look at the textbook differences—each variant has lived on our plant floor, and our team has adapted to the nuances of making and moving them.
Much of the material labeled “halonitrobenzene” out there misses customer requirements for trace impurity controls. Only regular, hands-on verification with chromatography and NMR catches what fast scales and aggressive trade practices miss. Third-party traders sometimes request blended lots for price breaks, but from our side, we hold to single-isomer, high-purity standards, because downstream headaches are expensive and preventable. The cost savings from looser grades can quickly evaporate when failed syntheses and residues gum up equipment. The right compound, made the right way, brings reliability instead of risk.
Chemical companies often talk about state-of-the-art production, but those of us on the floor know the real challenges unfold in everyday running. 2,4-Dichloro-3-Fluoronitrobenzene comes with its quirks. Safety precautions rank high, given the toxicity of nitroaromatics and volatility of chlorinated compounds. Past incidents in the industry—ranging from minor leaks to more serious containment issues—have pushed all reputable manufacturers to design processes with multiple barriers and safeguards. In our case, containment structures, scrubber systems, and fail-proof transfer protocols are always the backbone of our system.
Raw material sourcing determines much of what comes next. Each reactor charge must use feedstocks with known impurity profiles and stable supply lines. Our purchasing group works closely with primary suppliers, testing lots at multiple points before green-lighting production. On the shop floor, operators use digital logging to catch deviations as early as possible, and shift supervisors walk the plant daily. These steps are far from glamorous, but they explain why some products reach consistent purity while others struggle batch-to-batch.
Cleaning between batches proves another hurdle. After years of operation, our maintenance routines marked where cross-contamination risk runs highest. Using dedicated lines or validated cleaning cycles can look expensive on paper, but pays off when incoming orders demand strict batch tracking or custom specs. Investment in specialty alloys and polymer-lined vessels gives us room to pivot between products with overlapping requirements, always minimizing downtime.
Waste management also features in ongoing improvement. Nitroaromatic waste presents challenges in terms of both local regulation and environmental responsibility. In-house treatment units neutralize and break down potential hazards, and waste audits are conducted more frequently than most mandates require. Having learned from past experience, getting every team member engaged in tracking and reporting waste metrics feels essential to long-term sustainability.
Quality assurance isn’t a theoretical promise in our operation—it’s documented with each shift change, batch record, and internal audit. Our laboratories run advanced chromatography, spectroscopy, and titration checks at three points in the production cycle. The data from these tests doesn’t just sit in a database. Each result informs maintenance intervals, equipment calibration, and ongoing process tweaks. Any time results deviate from specification, we halt and investigate rather than pushing subpar lots through the pipe.
Working directly with customers, we listen to feedback on solubility, reactivity, and reaction yield from their own plants and labs. Over time, this two-way street built mutual trust and improved our own understanding of real-world product performance. Where occasional test runs flagged minor issues, joint investigations turned up fixes that closed gaps quickly.
Labeling and traceability matter as well. We print batch codes and full analytical reports with every shipment, ensuring that downstream users can trace every container back through our records. For sudden issues or recalls, this transparency shrinks response time and prevents headaches across the supply chain. In time-sensitive production environments, quick access to records can keep a campaign on track, avoiding bottlenecks when a question arises.
Direct conversations with chemists, engineers, and purchasing teams set the tone for how, and why, we produce 2,4-Dichloro-3-Fluoronitrobenzene. Having a real production line grants flexibility and insight that cannot be reproduced with a PowerPoint or a PDF. If a customer requests solvent-specific packaging or a modified impurity cutoff, our technical group runs lab trials and adapts conditions with minimal lead time. We see ourselves as a partner, not just a supplier. Challenges surface all the time, from last-minute logistics scares to a late design change on a synthesis route. Solutions happen on the ground. Most of our senior production staff remain on call for such events, knowing that manufacturing reliability travels hand-in-hand with trust.
This collaborative method includes site visits, customer audits, and roundtable reviews with industry experts. By opening our doors, we learn what matters most downstream. In past years, these sessions have led to process tweaks, new packaging concepts, and direct investment in bulk handling infrastructure. For us, the learning process runs both ways: Customer input sharpens our approach, and reliability cements long-term relationships.
Making and moving nitro and halogenated aromatics draws intense regulatory scrutiny. From the earliest stages of process planning, our engineering and compliance teams map each procedural step to international and local guidelines. We study not only what the law demands, but what current best practice recommends—particularly in the areas of containment, emissions control, and personnel protection. We engage directly with external auditors and industry groups, benchmarking against what’s working in other plants and adapting those lessons internally.
As regulations change, compliance isn’t just a yearly box to check but a living process. Ongoing employee training, investment in environmental controls, and plant upgrades translate to safer products and workplaces. Our environmental department analyzes runoff, emissions, and residue to ensure nothing falls outside safe limits. Where possible, we seek out greener reagents, closed-loop systems, and recycling strategies without sacrificing product quality. Experience has shown that proactive engagement builds both a safer factory and a better reputation with inspectors and neighbors alike.
Volatility affects every specialty chemical, and 2,4-Dichloro-3-Fluoronitrobenzene is no exception. From shifts in raw material prices to broader global events, the margin for error runs thin. Holding fixed inventory targets and working off long-term supply contracts helps manage swings that could otherwise disrupt production. Our logistics group tracks global freight and customs bottlenecks, rerouting shipments and building in redundancy so delays don’t pass down the chain.
Innovation doesn’t just happen in R&D labs. Sometimes it means fine-tuning reaction parameters to cut cycle time or energy use. Other times, it comes from trialing new catalysts or designing unique reactors for sensitive intermediates. Experience tells us that small upgrades, repeated consistently, compound into big reliability gains. While some manufacturers press for record batch sizes with little regard for process drift, we prefer steady improvement—always measuring, validating, and recalibrating where possible.
True value in specialty chemical manufacture flows from committed expertise. Many of our plant team members have worked on the same lines for years, watching process tweaks play out and learning from every challenge. We believe strongly in mentoring the next generation of plant operators and chemists, teaching what textbooks can’t show. Knowledge stays fresh because it’s applied, tested, and questioned on the ground—not simply recited from manuals.
Our technical team runs regular knowledge-sharing sessions where both successes and near-misses are dissected without pretense. Lessons get documented, improvements tracked, and the focus remains on continual, honest assessment of both our equipment and our people. Mistakes—though rare—become training moments for everyone. This transparency helps instill real confidence in our ability to deliver, batch after batch, even against the toughest market or technical odds.
Product standards and reliability look different on a trading platform compared to a manufacturer’s floor. Traders and distributors often assemble lots from mixed sources, sometimes blending or repacking to maximize reach and margin. From our point of view, only thorough in-house control can guarantee the traceability and performance our customers demand. Routine sampling, in-process validation, and mastery over every unit operation set a strong foundation for product confidence.
Many end users discovered, usually through difficult experience, that seemingly identical chemicals sourced via intermediaries led to batch variability, off-odors, or persistent compatibility headaches downstream. The real cost of a “cheaper” drum appears only after lost production hours or the need to clean fouled reactors. By contrast, our vertical integration offers a clearer chain from raw material to delivered drum—each stage under our own documentation and supervision.
Modern chemical industries demand more accountability than ever before, not just for headline safety but for day-to-day operational efficiency. A batch of 2,4-Dichloro-3-Fluoronitrobenzene with hidden impurities may pass cursory inspection yet compromise catalyst life, introduce unplanned side-products, or create instability in stored formulations. Our commitment to purity shows through two decades’ worth of customer feedback and internal benchmarking. Every improvement we make on the floor has a ripple effect at customer sites, reducing total cost of operation.
Consistency is earned by repetition, vigilance, and an unwillingness to cut corners. Ongoing dialogue with users and close monitoring of every parameter—temperature, pressure, residence time—preserve the reputation of our product and the businesses that depend on it. We treat each batch as a reflection of our name and our process mastery, knowing that small mistakes compound over time and across applications.
Operating a chemical manufacturing facility is never static: Regulations tighten, expectations rise, and technology evolves. Looking ahead, new downstream applications for 2,4-Dichloro-3-Fluoronitrobenzene will mean sharper controls, creative engineering, and even closer links between our process team and the user labs. Requests for greener chemistry, higher purity, special impurity cutoffs, and non-traditional packaging formats keep us on our toes.
We expect to see new interest from battery and electronic material firms, given the continued search for unique halogenated aromatics in advanced materials. As the buyer base diversifies, our experience as a producer—not a middleman—positions us to adapt. The mindset of a chemical manufacturer always ties reliability to partnerships and the discipline of process improvement. For each challenge, the solution begins with a commitment to transparency, technical excellence, and genuine listening.
Based on practical, daily experience, manufacturing 2,4-Dichloro-3-Fluoronitrobenzene isn’t just an industrial routine. It is a continual exercise in expertise, attention to detail, and the will to meet real-world requirements with accountability. That approach stands behind every kilogram that leaves our floor.