Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2,4-Diaminoanisole Sulfate

    • Product Name 2,4-Diaminoanisole Sulfate
    • Alias 4-Methoxy-1,3-phenylenediamine sulfate
    • Einecs 226-682-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    501776

    Chemical Name 2,4-Diaminoanisole Sulfate
    Cas Number 39156-41-7
    Molecular Formula C7H10N2O·H2SO4
    Molecular Weight 254.26 g/mol
    Appearance Gray to beige or violet powder
    Solubility Soluble in water
    Melting Point 222-226°C (decomposes)
    Synonyms 2,4-Diamino-1-methoxybenzene sulfate
    Odor Odorless
    Pubchem Cid 10218789

    As an accredited 2,4-Diaminoanisole Sulfate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Sealed amber glass bottle containing 100 grams of 2,4-Diaminoanisole Sulfate, labeled with hazard warnings and chemical identification details.
    Shipping 2,4-Diaminoanisole Sulfate should be shipped in tightly sealed containers, protected from moisture, light, and incompatible substances. It must be labeled per hazardous materials regulations and comply with all applicable transportation guidelines. Ensure proper documentation, handle with care, and store upright during transit to prevent leakage or contamination.
    Storage Store 2,4-Diaminoanisole Sulfate in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances such as oxidizing agents and acids. Protect from light and moisture. Clearly label the storage container and keep it in a designated chemical storage facility. Follow appropriate safety protocols and regulations for handling hazardous materials.
    Application of 2,4-Diaminoanisole Sulfate

    Applications of 2,4-Diaminoanisole Sulfate in Industrial Manufacturing

    2,4-Diaminoanisole Sulfate serves as a critical intermediate in several high-value industrial production chains, supporting sectors where precise formulation, regulatory compliance, and batch-to-batch reproducibility drive procurement decisions. Below, we outline real-world downstream application scenarios, detailing industry protocols, formulation guidelines, process workflows, and associated finished goods.

    1. Oxidative Hair Dye Manufacturing

    Hair colorants that yield long-lasting shades require oxidative dye precursors with high purity and uniform reactivity in cream, gel, or liquid bases. Formulators select this compound for intense brown and black tones after rigorous evaluation of stability in the presence of hydrogen peroxide and ammonia. Factory QC labs monitor both the degree of polymerization during dye oxidation and byproduct minimization to meet leading safety and labeling standards in personal care markets.

    Industry compliance standards

    • EU Cosmetic Regulation (EC) No 1223/2009 (Annex III, entry 8)
    • U.S. FDA Color Additive Status for hair dyes (21 CFR 73.2396)
    • Japan MHLW Standards for Cosmetics Amendment
    • ISO 22716:2007 (Cosmetics—Good Manufacturing Practices)

    Typical usage ratio

    • 0.1% – 1.0% of total formulation weight; precise ratio varies per dye shade intensity and compatibility with other color precursors. Adjust higher in formulations seeking stronger cool undertones.

    Downstream process integration

    • Dispersed at the aqueous mixing stage with other dye bases; follows filtration and pH adjustment before emulsion with oils/waxes for finished hair coloring systems. Monitoring of heat and sequence ensures full dissolution and reaction uniformity.

    Final product types

    • Oxidative permanent hair dyes (cream, gel, emulsion formats)
    • At-home and salon-grade hair coloring kits
    • Professional color developer sets
    • Pre-mixed oxidative tint concentrates

    2. High-Performance Inkjet and Textile Ink Formulation

    The compound plays an essential role in synthesizing specialty pigments for digital inkjet inks and textile printing applications, where fine particle dispersion and lightfastness determine the commercial viability of ink systems. R&D teams optimize particle mill processes to achieve nanoscale pigment size, which directly influences print resolution, substrate adhesion, and penetration uniformity on a range of paper or textile bases.

    Industry compliance standards

    • ISO 2836:2004 (Graphic technology—Printability—Resistance to chemicals)
    • OEKO-TEX Standard 100 (for textiles touching skin)
    • EN 71-3:2019 (Migration of certain elements in toys, for children's textile prints)
    • REACH (EC) No 1907/2006—SVHC limits for packaging inks

    Typical usage ratio

    • 0.2% – 0.8% of ink formula solids, depending on color strength required and printhead compatibility. Adjusted downward in multi-color blends to prevent nozzle clogging in high-speed printers.

    Downstream process integration

    • Introduced at pigment synthesis or azo-coupling stage, then compounded into ink dispersions after filtration. For digital inks, occurs before surfactant and viscosity modifier addition; careful mixing preserves particle size distribution.

    Final product types

    • High-definition inkjet inks for commercial packaging and industrial labeling
    • Textile printing inks for cotton, polyester, and blends
    • Fabric marker refills
    • Specialty pigment dispersions for security printing

    3. Color Developer Synthesis in Photographic and Imaging Industries

    Photographic processing and certain imaging paper manufacturing rely on stable color developers that generate consistent tone under carefully controlled chemical conditions. The compound functions as a low-impurity aromatic amine precursor, meeting requirements for batch lot reproducibility in high-resolution film and paper developer solutions. Quality teams routinely audit supply batches for heavy metal contaminants and unreacted amine fractions as required by imaging suppliers.

    Industry compliance standards

    • ISO 18909:2006 (Photographic image stability—color images)
    • ANSI/NAPM IT9.2 (Imaging Materials—Photographic Processes)
    • RoHS 2 Directive 2011/65/EU (exclusion lists for electronic imaging devices)
    • UL 764—Chemicals for Developing Photographic Films

    Typical usage ratio

    • 0.3% – 0.7% of color developer mix by weight; level determined by color depth and fade resistance specifications in finished print or film.

    Downstream process integration

    • Charged into the reaction vessel with other developer bases at temperature-controlled, alkaline pH stages. Following completion, mixtures undergo multi-stage purification before blend with stabilizers and buffering agents for end-use developer solutions.

    Final product types

    • Photographic paper developers (RC and FB typepapers)
    • Color developing solutions for motion picture and medical X-ray films
    • Digital print lab processing chemicals
    • On-site color developer cartridges for photo printers

    4. Organic Synthesis Intermediate for API and Specialty Molecule Production

    This material provides a foundational aromatic amine structure vital for synthesizing various specialty molecules, including pharmaceutical building blocks and chemical intermediates. Contract and generic manufacturers incorporate it at the multi-step reaction phase, where its purity profile impacts downstream API regulatory filing data and plant cleaning validation. Each batch meets trace metal and solvent residue requirements documented in site-specific DMFs or technical data submissions.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • USP-NF and Ph. Eur. reference for residual solvent and impurity controls
    • 21 CFR Part 211 (FDA cGMP for finished pharmaceuticals)
    • China Drug Master File (DMF) submission protocols

    Typical usage ratio

    • Variable: input weight calculated per intended molecular conversion; generally 0.5–1.5 molar equivalents relative to target molecule in batch synthesis. Scaling adjusted during route optimization to balance cost and conversion efficiency.

    Downstream process integration

    • Added in the initial or intermediate step as an amine donor or coupling component during organic synthesis. Subsequent purification, crystallization, or isolation steps depend on the specific target compound’s properties.

    Final product types

    • Pharmaceutical and veterinary drug intermediates
    • Specialty imaging agents for clinical diagnostics
    • Performance chemical intermediates for UV absorber or antioxidant production
    • Analytical reference materials

    5. High-Purity Dye Manufacturing for Laboratory and Analytical Markets

    Specialty labs, diagnostic kit suppliers, and histology reagent manufacturers require dyes with low background interference, batch-to-batch color fidelity, and certified impurity profiles. Here, the compound acts as a controlled chromophore precursor whose performance influences both reproducibility in staining and accuracy in spectrophotometric assays. Regulatory documentation supports audit trails for traceability and method validation.

    Industry compliance standards

    • ISO 17034:2016 (Reference Material Producers—General Requirements)
    • FDA QSR 21 CFR Part 820 for medical device reagents
    • ASTM D1500 (Color of Petroleum Products by Visual Comparison)
    • CLSI GP42-A6 (Preparation and Testing of Reagent Water in Lab Use)

    Typical usage ratio

    • 0.05% – 0.2% of total formulation for most analytical dyes; minimized further to reduce interference in quantitative assays. Lot-specific optimization may be required.

    Downstream process integration

    • Dosed at chromogenic reaction stage, followed by multiple purification and filtration steps. Integrated final blending with stabilizers, buffer salts, or solvents based on client-specific end-use.

    Final product types

    • Histological and cytological staining kits
    • Colorimetric reagents for laboratory assays
    • Spectrophotometric measuring standards
    • Analytical grade dyes for reference chemistry
    Free Quote

    Competitive 2,4-Diaminoanisole Sulfate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2,4-Diaminoanisole Sulfate: Precision for Performance Dyes

    From Our Reactor to Your Application

    Every batch of 2,4-Diaminoanisole Sulfate starts with a commitment to detail during the synthesis process. Running reactors at the right pressure and keeping a keen eye on temperature holds center stage in reliability here. One stray reading and you get impurities, which nobody wants in an intermediate for colorants and speciality chemical work. After two decades putting this compound through distillation columns, filter presses, and drying ovens, we do not take shortcuts. Out in the market, “close enough” often means cutting quality. We’d rather troubleshoot an extra hour than send out anything questionable.

    Over time, we’ve taken in samples produced by other factories. Some give off strange odors. Some arrive with a dustiness that points to poor drying. Checking particle size, we sometimes see clumping or grains too fine—leading to uneven blending and unstable coloration in the end-use process. We aim for clean, off-white to pale gray crystalline powder, no harsh aromas. Every drum seals tight against moisture intrusion, reducing caking during storage.

    Model and Usual Specifications

    On the shop floor, we label our primary product line as Model 2,4DA-99. What matters most to our customers—especially those in colorants for textiles, inks, and hair dye intermediates—is purity. Regular output checks in at 99% or above HPLC, ash well below 0.1%, very low heavy metals, and strict moisture control. These checkpoints stem from direct feedback. Years ago, a customer reported color drift in oxidizing dyes. We adjusted our washing process, lowered sulfate contamination, and delivered the next lot with consistent tone. Little changes echo all the way through to the final shade.

    People sometimes call and ask about other grades. We do not push lower purities, because side products like 4-nitroanisole—common if oxygen levels during synthesis rise—bring risk to downstream reactions. For those running batch dye systems, consistency makes their recipes turn out right, batch after batch.

    Making Colorants Stable and Predictable

    Why do so many specialty dye makers and lab formulators want 2,4-Diaminoanisole Sulfate? Reliability in batch processing is the clear answer. In hair dyes, for example, developers mix it with oxidizers to create lasting colors. An inconsistency in the sulfate lots shows up as weaker or unpredictable final color intensity. Dull batches slip through now and then from less cautious plants; salon industry customers spot them immediately.

    Using stable 2,4-Diaminoanisole Sulfate helps address regulatory and consumer safety concerns too. Some countries have harsh restrictions on trace amines and metal content due to demonstrated toxicity in older dye chemical grades. Our plant works with closed systems and high-grade feedstocks, keeping contaminants from entering the supply chain. Every certificate we issue comes from tests in our on-site lab, not from assumptions or indirect calculations.

    How We Stack up Against the Market

    After working on contracts with both global conglomerates and small local producers, we know that not all chemical suppliers handle quality as tightly as we do. Some ship sulfonated amines with little control of particle size distribution. Those powders end up dusty, leading to messes in production—or granules too dense, refusing to blend. We run regular sieving analysis and sieve retention not only during the final packaging stage, but after every drying pass.

    Batch traceability traces back to actual reactor runs, not just paperwork. Faulty batches have led to some horror stories: interrupted color reactions or off-smelling powder. In our experience, those situations trace back to off-spec intermediates or sloppy washing that leaves sodium or iron behind. As a manufacturer, these are the headaches we work to eliminate, preferring to bear higher input costs if it means zero production failures for our customers.

    Now and then, customers approach us asking for “substitutes” or “lower-cost” alternatives. Some resellers offer mixtures of 2,4-diaminoanisole with cheaper by-products or even unrelated amines to drop the headline price. We do not follow this path, recognizing the reputation damage that comes from a single bad batch. Discerning end-users in the pigment, syntheses, and ink segments spot these mismatches quickly. Lost batches and wasted dyes cost far more in the long run than a tiny discount on raw materials.

    Typical Usage and Safety Considerations

    Every kilogram we sell enters a process where worker safety and environmental stewardship remain under sharp focus. 2,4-Diaminoanisole Sulfate works as a foundational intermediate for oxidative dyes, hair colorant precursors, and high-performance printing inks. The compound’s strong coupling ability makes it valuable in providing shades from deep blue-black to subtle browns, depending on the formulation route.

    In textile applications, dosing inaccuracies or uncontrolled chlorination in the previous steps can lead to unwanted by-products, which sometimes turn up as off-hues or lead to fabric damage. Our operators communicate directly with downstream users to clarify mixing protocols and recommend storage at low humidity to prevent caking and to maintain easy charging into blending reactors or mixers.

    Our experience working with regulatory agencies underlines the need for thorough documentation at every stage. Some regulations—even within single jurisdictions—shift with little notice, especially regarding amine derivatives. We maintain an open file on every batch, noting feedstock lot numbers, reaction logs, and QC checks. When auditors or customer quality assurance teams visit, they walk into a production line with clear, on-demand documentation. Our site engineers welcome these visits, ready to show exactly where each batch originated and what steps we took to guarantee purity and product safety.

    Differences From Similar Compounds

    A question we receive frequently concerns comparisons with other isomers and related intermediates, such as 4-Amino-2-methoxyaniline or unsubstituted diaminoanisoles. The distinctions matter most for chemists in the lab designing reaction pathways, but the impact shows up clearly in application. The unique combination of the methoxy group on the aniline ring and the two amine groups leads this sulfate salt to give high reactivity and a distinct shade effect, particularly in hair dyes and textile coloration. Swapping it for close relatives—such as 3,4-diaminoanisole—often introduces shift in dye tone, lowers yield in oxidative color development, or results in lower resistance to fading from UV exposure.

    Handling differences come to light, too. Other manufacturers ship simple amine hydrochlorides instead of sulfate forms. These can absorb water from the air, clump up, or even degrade faster, especially during summer humidity spikes or shipment delays. Our sulfate salt version holds up better in coastal or tropical regions, as confirmed by third-party climate tests for stability and shelf life. The sulfate’s low solubility in some solvents also helps keep it from leaching or “creeping” through seams of poorly closed bags, a problem that shows up as product loss in remote warehouses.

    In our production, tighter control over reaction timing and post-synthesis washing minimizes the formation of colored by-products, which sometimes tint batch outputs from less attentive factories. Customers notice: a cleaner powder lets them prep lighter, more predictable shades without muddiness or need for extra purification.

    Serving Changing Needs in New Markets

    Rules and habits in chemical applications never stand still. Demand for lower impurity loads and “greener” chemistry grows each year. Industrial buyers expect suppliers to move with these standards, not follow behind. We respond by investing in upgraded filtration and effluent treatment, shifting to higher-purity feedstocks, and maintaining a proactive approach in receiving industry certifications—not waiting for regulators to chase after us.

    Sometimes, being a manufacturer in this space means explaining what sets our products apart from those of a trading company. Traders may handle multiple items without being able to answer technical questions or resolve a process hiccup in a customer's facility. We keep direct lines open to plant engineers, not just for sales but for troubleshooting and ongoing improvement. A few years back, one printer ink company flagged a batch that didn’t dissolve properly under fast mixing. Working side by side with their lab, we traced the issue to an unnoticed tweak in our drying cycle, adjusted it, and solved the problem on the next run, strengthening years of partnership.

    Perspectives on Supply Chain Issues and Sustainability

    Trust grows from consistent supply and clear communication. Global shortages of fine chemical building blocks have rattled our industry in recent years. Some buyers have turned to brokers, only to discover contamination or unreliable documentation downstream. As the manufacturer, we buffer our inventory, maintain healthy relationships with upstream suppliers, and invest in backup production capacity. Spikes in demand—fires at suppliers, weather disruptions, new dye launches—do not catch us off guard. We can ship immediately from in-house warehousing or ramp up within days. Customers with strict JIT manufacturing routines appreciate predictability in both schedule and documentation.

    Sustainability has become a shared goal. Across more than twenty years of plant improvements, we've cut water and solvent use with closed-loop recovery. We treat our effluents on site, sending none of the process residues offsite without full neutralization or approved handling. Every year, our process engineers propose new tweaks to cut the energy curve further. Once, a planned batch upgrade slashed steam usage by 12%, paid for itself, and reduced the workload for our distillation crew.

    Adjusting our product specifications away from older, dirtier syntheses has not always been easy. Some legacy users requested “the old way,” but seeing less environmental impact and better worker safety wins their confidence. We learn from industry studies and associations—following risk reports and keeping open lines to global partners. We have faced audits from multinational dye companies who drilled deep into our sites to verify claims. These experiences hone our protocols and reinforce our belief that clear traceability, consistent process discipline, and honest refusal to ship anything short of specification keep our customers ahead in regulatory compliance and technical reliability.

    The Real-World Value: Answers, Support, and Experience

    At this point, our strength as a manufacturer rests on a willingness to support customers after the sale. Our technical staff field daily questions on powder flow, dye shade drift, and formulation tweaks. Sometimes, new legislation prompts customer requests for grade certifications rapidly. We deliver complete batch paperwork out of our own QC archives, not a slow search through outsourced testing labs.

    Speed counts. Trouble on a customer line often means lost batch time and overtime costs. Our plant crew once drove samples overnight across country, got confirmation back from the user's lab, and began a production run within twenty-four hours. Follow-through like this helps customers launch products faster and with fewer worries about dye performance and reactivity.

    Feedback loops run in both directions. Customers share complaints and process headaches; we note what works and what doesn’t in their setting. Sometimes, we adapt package sizes, adjust drying parameters for different climates, or revise our post-filtration checking. Our practical insight comes not just from theory, but from years of hands-on troubleshooting and listening.

    Meeting Expectations Today, Building for Tomorrow

    Newer customers entering the colorant industry care far more now about documentation and support than buyers of the past. They want photographic proof of each batch, compliance certificates, worker safety training, and trace impurity reports. As manufacturers, we saw this change coming and built our lab resources to keep up. No one has to ask twice for a full analytical dossier; every shipment comes with transparent supporting data.

    Dealing with post-pandemic supply chain complexities, we recognize that sharing technical expertise is just as important as providing the right product. Many of the requests now include guidance on mixing, warnings about regulatory changes in amine derivatives, and rapid response to out-of-spec observations. We give open access to engineering managers, chemists, and people actually familiar with the equipment—no need to wait days for a generic response from a sales desk disconnected from production reality.

    Our plant’s legacy is built on long-term customer partnerships, a direct understanding of the chemistry, and a drive for practical, sustainable manufacturing. Each sack of 2,4-Diaminoanisole Sulfate we deliver carries decades of continuous process improvement, sharp eyes on purity, and an open door for questions, troubleshooting, and building the next generation of safe, high-performing colorants and dye intermediates.