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2-(4-Chloro-2-Methylphenoxy)Propanoic Acid

    • Product Name 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid
    • Alias Mecoprop
    • Einecs 253-660-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    646476

    Iupac Name 2-(4-chloro-2-methylphenoxy)propanoic acid
    Cas Number 16484-77-8
    Molecular Formula C10H11ClO3
    Molecular Weight 214.65 g/mol
    Appearance White to off-white crystalline solid
    Melting Point 105-108°C
    Solubility In Water Slightly soluble
    Logp 2.88
    Pka 3.77
    Synonyms Mecoprop, MCPP
    Smiles CC1=C(C=CC(=C1)Cl)OC(C)C(=O)O
    Storage Temperature Room temperature

    As an accredited 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid is packaged in a sealed, amber glass bottle with a tamper-evident cap.
    Shipping 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid is shipped in tightly sealed containers to prevent moisture absorption and contamination. It should be transported in compliance with local regulations, typically as a non-hazardous material. Protect from physical damage and store in a cool, dry place away from incompatible substances. Safety documentation accompanies all shipments.
    Storage 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers. Ensure the storage area is secure and appropriately labeled. Avoid moisture and store at room temperature to maintain compound stability and prevent degradation.
    Application of 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid

    Applications of 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid in Industrial Manufacturing

    As a direct manufacturer, we supply 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid for advanced industrial applications. Our material supports key chemical synthesis, specifically within regulated, process-focused B2B segments. Below, the main application tracks are outlined, each with distinct compliance, dosage, integration, and finished goods notes.

    1. Selective Herbicide Active Ingredient for Agrochemical Formulations

    Many major agrochemical producers use this compound as an intermediate or active ingredient in the synthesis of selective systemic herbicides, including members of the aryloxyalkanoic acid family. Most process lines require high-purity material to ensure precise crop-selectivity on cereals and grass crops while maintaining regulatory approvals for environmental safety and residue tolerances. Downstream, the formulation process involves synthesis blending, neutralization, and formulation into emulsifiable concentrates or water-dispersible granules. Product quality centers on stability, solubility, and field performance in commercial agricultural applications.

    Industry compliance standards

    • FAO Specifications on Pesticide Active Ingredients
    • EU Regulation (EC) No 1107/2009 for Plant Protection Products
    • EPA 40 CFR Part 180 Tolerances
    • China’s GB/T 1600-2011 Standard for Agrochemical Actives

    Typical usage ratio

    • 20–40% by weight in technical concentrate synthesis (adjusted per crop, regulatory limits, and formulation type)

    Downstream process integration

    • Introduced post-esterification during the actives blending phase
    • Reacted with selected alkyl groups for ester herbicidal final forms
    • Mixed with surfactants and carriers in formulation tanks
    • Quality control verifies isomer and impurity profiles before packaging

    Final product types

    • Emulsifiable concentrate herbicide products (ECs)
    • Water dispersible granules (WDGs)
    • Suspension concentrate herbicides (SCs)
    • Bulk technical grade active ingredient for downstream synthesis

    2. Fine Chemical Intermediate for Pharmaceutical Synthesis

    This raw material serves as an essential building block in the synthesis of certain lipid-modifying agents, especially in the fibrate class of medications. Pharmaceutical manufacturers use it as a starting acid or acid derivative to produce intermediates under tightly regulated GMP conditions. Integration takes place within approved reaction vessels, using validated process controls for temperature and purity. The isolating and refining steps determine the impurity profile critical for API quality, with batch records maintained for traceability and pharmacopoeial compliance.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practices for Active Pharmaceutical Ingredients
    • EU GMP Directive 2003/94/EC
    • Pharmacopoeia monographs (USP, EP, ChP, as applicable to final API)
    • FDA 21 CFR Part 210/211

    Typical usage ratio

    • Stoichiometric ratios determined by target API synthesis; typically 1.0–1.5 molar equivalents per key intermediate step

    Downstream process integration

    • Charged during initial reaction as primary acid precursor in synthetic sequence
    • Refined via crystallization, filtration, and purification stages
    • Monitored for residual solvent and impurity levels before conversion to subsequent intermediates or APIs
    • Separate, closed process lines for GMP versus technical grade batches

    Final product types

    • Pharmaceutical intermediates for fibrate and related medications
    • API precursors following further synthetic modification
    • Certified reference standards for stability and impurity profiling
    • Advanced bulk intermediates shipped for final API manufacturing

    3. Resin Modifier in Polymer Additive Manufacturing

    Major polymer resin producers incorporate selected phenoxy acid derivatives, including this compound, to adjust plasticizer performance, resin flexibility, and solvent resistance in specialty polymers. The material is dosed in polymerization reactors as a functional monomer or modifier, often under inert conditions to control molecular weight and branching. Quality assurance focuses on compatibility with base resins, migration behavior, and residual monomer levels. Downstream, modified resins serve in wire coatings, specialty films, and engineered composites.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 (monomers and additives registration)
    • UL 94 Flammability Standards for Polymeric Materials
    • ISO 9001-certified resin production quality systems
    • Specific industry performance requirements for cable, packaging, or automotive resin applications

    Typical usage ratio

    • 0.5–3.0% by weight in resin batch, tailored to desired end-use flexibility and chemical resistance

    Downstream process integration

    • Dosed into polymerization vessels during main chain build-up stage
    • Reactive process requires temperature- and agitation-controlled blending
    • Post-polymerization, producers analyze additive distribution via GC or NMR
    • Final resin pellets tested for physical and mechanical enhancements

    Final product types

    • Modified wire insulation and cable sheathing resins
    • Flexible packaging films with enhanced solvent barrier
    • Specialty automotive component polymers
    • Technical-grade composite resins for electronic encapsulation

    4. Synthesis Aid in Fine Organic Chemical Production

    Producers in the fine chemicals sector use this compound as an auxiliary agent during the preparation of specialty chemical intermediates. It acts as a nucleophilic reagent or provides designer acid functionality for complex molecule construction, particularly where halogenated phenoxy structures are required. Accurate dosing and process timing are crucial, as the compound’s reactivity impacts subsequent transformations. Isolation protocols enable high yield and reproducibility, which aligns with downstream demands for specialty dye, analytical reagent, and agro-intermediate production.

    Industry compliance standards

    • ISO 9001/14001 Quality and Environmental Systems
    • Chemical Control Laws for Intermediate Chemicals (e.g., China’s General Administration of Customs and MEE)
    • Responsible Care Product Stewardship Codes
    • Batch documentation and traceability as per EU and US specialty chemical requirements

    Typical usage ratio

    • 1–10% loading by weight, depending on downstream target molecule and synthetic step complexity

    Downstream process integration

    • Fed during key nucleophilic reaction or alkylation stages
    • Monitored for product selectivity and side-product control
    • Process may incorporate phase-transfer catalysis or in situ neutralization for acid balance
    • Intermediate isolated via precipitation, solvent extraction, or chromatographic purification

    Final product types

    • Specialty dye intermediates for industrial colorants
    • Niche agrochemical intermediates for next-step synthesis
    • Custom reagents for analytical and laboratory use
    • Functionalized building blocks for high-value fine chemical portfolios
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    Certification & Compliance
    More Introduction

    2-(4-Chloro-2-Methylphenoxy)Propanoic Acid: A Manufacturer’s Perspective

    Why 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid Matters in Today’s World

    Producing 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid (often abbreviated as CMPPA or simply referred to as a core aryloxyalkanoic acid compound) carries a responsibility that stretches from our laboratories to the fields that depend on it. CMPPA gained its place as a high-value intermediate in the agrochemical sector, particularly for selective herbicides that support cereal, pasture, and industrial crop management. Each batch that leaves our facility reflects years of process optimization, quality learning, and a direct response to the nuanced needs of farming professionals. Unlike more basic phenoxyalkanoic acids, our process engineers dedicate themselves to addressing the little variables—impurity levels, particle morphology, and precise consistency—because even minor deviations make a real difference to formulators and end-users.

    Production Approach and Model: Experience, Consistency, and Scale

    Our team sees every kilogram of CMPPA as a reflection of careful chemistry and stubborn commitment to clean, reproducible output. CMPPA doesn’t exist in a vacuum. It requires selectivity at each stage, from the chlorination of toluidines through to precise etherification and carboxylation steps that define its final quality. Over the years, we’ve worked alongside formulation chemists who appreciate consistency in melting point and crystal habit. The model we produce emphasizes low residual solvents and minimal trace impurities, given their tendency to complicate downstream synthesis. Equipment calibration, process analytics, and solution pH monitoring contribute more to the end-product here than in lower-value commodity acids. Routine isn’t just about repetition; it’s a hard-learned pathway to reliability.

    Understanding Specifications from a Manufacturer’s View

    Direct feedback from agrochemical formulators teaches us to focus on real bottlenecks. Analytical purity generally sits at 98% minimum (by GC or HPLC), not as an afterthought but because even low-level off-spec content can alter crystallinity and formulation behavior. Controlling water content through vacuum drying curbs caking and clumping problems, especially during bulk handling and storage. We target insolubles and color bodies, knowing their presence leads to batch-to-batch variances in the field and complications in blending. Standard physical forms range from free-flowing powders to microcrystalline variants, according to practical mixing and suspensibility feedback. Each shipment reflects this accumulated experience, as much as laboratory specification.

    Putting CMPPA to Work: Aggressive Weeds, Tough Environments

    CMPPA’s primary routes of application lie in selective herbicide production, where end-use reliability keeps cropland productive season after season. The ‘Chloro’ and ‘Methyl’ positioning matters: these functional groups push selectivity and metabolic stability in target weed species. This is why professional growers turn to herbicide products where CMPPA forms the core. Our manufacturing method doesn’t chase trendy labels or fleeting market preferences. We’ve seen that field performance depends most on product regularity and trace impurity management. The acid’s fine balance of electron-rich and -withdrawing effects also helps research chemists target analogs and new combinations when resistance patterns shift.

    What Sets CMPPA Apart from Similar Intermediates

    Every year, raw material options and synthetic routes evolve. In practice, not every ‘comparable’ compound handles the same way in the lab or in the field. For instance, 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid achieves a unique solubility and dispersibility, making it easier to formulate in low-organic-solvent systems. We’ve run comparative pilot batches with both classic phenoxy acid herbicides and their methylated/chlorinated cousins. CMPPA outperforms more basic propanoic acids by offering a tighter melting point range, cleaner odor profiles, and less tendency toward discoloration on storage. Drawn-out supply chains struggle with inconsistent crystallinity; our manufacturing bias favors structure-control so the acid behaves predictably through spring and summer.

    Real-World Lessons from Years of Production

    There’s no shortcut in the move from R&D scale synthesis to bulk production. Over dozens of campaigns, we learned that solvent recovery and spent acid neutralization can throw subtle contradictions at even experienced teams. You get a truer understanding of process safety and emissions by spending time at the plant rather than the boardroom. Watching a batch process run under humid summer conditions tests both your vent scrubber design and your commitment to odor management. Operators and engineers who work alongside us know that hiding impurities with excessive washing leads to downtime later, not less. Factory teams expect the process to speak to them: if filtration times creep up or color shifts, something’s changed upstream, not downstream.

    On Application Versatility and Downstream Options

    Beyond the primary market in crop protection, CMPPA plays a growing part as a building block for more specialized actives in both research and industrial sectors. Organic synthesis groups value the compatibilities offered by its ether and acid functions. Lab development teams frequently experiment with side-chain modifications and esterification to access new herbicide scaffolds. That’s a trust built on consistent functional group presentation—no surprises, no unwelcome byproducts. Compared to simpler or less substituted analogues, CMPPA grants downstream chemists cleaner access to target molecules, easing both analysis and regulatory documentation.

    Managing Waste and Environmental Impact

    Twenty years in chemical manufacturing teaches restraint and mindfulness about waste. Reactive intermediates can be unforgiving. We focus on closed-loop systems to reduce mother liquor discards, lessen the load on wastewater plants, and harvest more of each key raw material. Quality doesn’t come from overreacting with highly active chlorinating agents or running massive stoichiometric excesses—solvents demand recovery, not venting. These aren’t talking points; efficiency and emissions controls run on a cycle of daily maintenance and commitment. Our operators have seen firsthand how better segregation of spent acids, improved catalyst recycling, and secondary containment protocols strengthen both product quality and long-term compliance. The product and the environment both get due attention, not just when a regulator stops by, but every day.

    Safety, Handling, and Storage in Practice

    CMPPA’s handling quirks come from its chemical structure. Sharp, mildly phenolic odor, potential for mild skin and eye irritation, and moderate dusting–we’ve tweaked plant protocols based on experience, not mere literature review. Operators wear masks and gloves, and we stress local ventilation not for citation’s sake but because everyone goes home to family at shift’s end. Closed bulk transfer lines cut down dust, especially as powder handling picks up in early spring runs. Through-it-all, we keep records—a habit enshrined because traceability interacts directly with both customer confidence and operator trust.

    Continuous Improvement from Batch Review and Customer Feedback

    No batch is perfect. Still, every outgoing drum moves with documentation—HPLC traces, moisture analyses, reactivity snapshots—because our customers’ results ride on the integrity of every shipment. Customers have taught us plenty over the years: a few parts per million of hydrolyzed byproducts make some runs foam; overly-rapid drying hardens the crystals to the point of difficult milling. We’ve made process adjustments that stay grounded in practical learning, not theoretical ideal. Review cycles usually link to feedback from the field, whether that’s a herbicide technician puzzling over flow rates or an R&D team mapping out a new formulation. That loop builds better product and, more critically, stronger people and relationships.

    What Quality Looks Like Up Close

    Quality here takes form in small details—crystals that don’t cake on storage, an acid that remains bright and colorless even after six months, a batch certificate that reads the same from start to finish. Our process analytics team runs the routine, grinding through hours of titration, spectrometry, and chromatography to catch specs that matter. There is pride and accountability in every number we sign off. Products headed abroad, especially where regulatory requirements demand added transparency, benefit from this daily grind. We speak plainly if a batch drifts outside the expected boundaries; action and trust depend on reliability, not hoping variances slip through unnoticed.

    Challenges Unique to CMPPA Compared to Similar Products

    Every chemical carries its own quirks, and CMPPA is no different. In our experience, its synthesis likes a narrow temperature window during chlorination, or the yield suffers and unwanted byproducts increase. Unlike more robust acids, slow cooling is essential—quick temperature drops spoil the crystal size, and that destroys downstream flowability. The acid’s intermediate polarity makes solvent selection for crystallization or purification tricky; the team spent several years adjusting protocols to get reproducible purity with a manageable environmental cost. These lessons matter most when demand scales and every percent of yield kicks in to protect margins and minimize waste.

    Product Differentiation: Beyond Simple Structural Claims

    Many external suppliers equate product difference with a line on a certificate. We walk a different path: every production cycle is a chance to see how fine control—on pH, on filtrate clarity, on color plate readings—delivers a consistently recognizable compound. Lab analysis catches some things, but those who have scooped handfuls of sticky batch powder or unclogged transfer chutes during humid spells know the real differences emerge on the factory floor. What we sell is not just a molecule, but a practical solution to the dozens of unpredictable events along the logistics chain. Ease of handling, stable reactivity, and controllable compliance hurdles—these mark a useful difference, not just an abstract one.

    Improving Through Investment and Training

    Progress in manufacturing runs on training and equipment investment as much as it runs on paper protocols. We allocate time each year for our operations crews to learn new hazards, troubleshoot old bottlenecks, and re-certify on critical systems—whether that’s a high-shear mixer or a nitrogen blanket system for critical stages. Investments go toward smarter tracking, more effective dust control, and better process controls. We see these costs as investments in predictability, both for us and for our customers. The payoff takes the form of fewer off-spec shipments, cleaner storage conditions, and a stronger foundation for lasting partnerships.

    Compliance and Documentation: Living Practices

    Every kilogram of CMPPA touches multiple layers of regulation, both for chemical content and transportation safety. Our compliance team stays current not out of obligation, but because a strong paper trail protects us and our partners in the long run. That means exhaustive batch records, regular sampling audits, and transparent declarations to regulators and customers alike. We translate regulatory feedback into practical action—extra rinses, adjusted handling times, or tailored labels—because the real cost of falling short runs far deeper than any fine or citation. Every piece of documentation reflects lived experience on the shop floor and the outcomes we share.

    Supply Chain Realities and What They Mean for Quality

    The chemical industry no longer works in isolation. Changes in global logistics and raw material supply shake even the best-run plants. We build flexibility into our raw materials sourcing to keep production steady, not just at peak times but across seasons when upstream issues slow the flow. Holding safety stock translates to smoother deliveries, and a better partnership with downstream formulators who can’t wait weeks for a batch correction. Our approach means talking directly with logistics, engaging with direct shipping routes where possible, and taking the hit on lead times when that’s the price for trust.

    Customer Support: From Sample Request to Full-Scale Rollout

    People working in chemical manufacturing know relationships matter as much as the molecule itself. Supply is more than selling: it’s helping formulators and researchers troubleshoot solubility shifts, validate melting points, or interpret odd results when weather and storage throw curveballs. We ship samples willingly not just for sales, but because pilot runs in a customer’s plant often reveal nuances you can’t catch in your own. Regular, straightforward dialogue with application scientists and supply-chain staff drives continuous improvement—those conversations teach us to resolve “mystery” off-notes or batch clumping before it becomes a headline issue.

    Looking Ahead: Innovation Built on Foundations

    Markets and regulations shift ever faster. Today, resistance management and formulation restrictions pressure suppliers to develop not just variants, but entirely new active scaffolds. CMPPA continues to stand out not just because of past performance, but because it still serves as a backbone for building next-generation actives. We support research partnerships with direct knowledge, offering insights into which starting materials, solvents, and process tweaks lead to the best yields and the safest, most effective compounds. Our manufacturing memory, captured in thousands of small process improvements, forms the backbone of this trust.

    Addressing the Future: Sustainability and Reliability

    The future of chemical manufacturing leans hard on cleaner practices, smarter process design, and honest self-reflection. CMPPA production won’t slip into obsolescence, because the need for efficient cropland management and reliable chemical building blocks won’t disappear overnight. Our future lies in refining what we already do well, recognizing the points of failure, and investing in both corrective technology and team skills. Every lesson from a messy filter cake or a delayed batch shipment acts as a step toward better practice.

    Summing Up: A Product Shaped by Practice, Not Just Theory

    Making 2-(4-Chloro-2-Methylphenoxy)Propanoic Acid isn’t an abstract exercise—it’s a daily routine of persistence, adaptation, and honest feedback. What arrives at the customer’s door was shaped by real people tackling real-world limitations. Every drum or bag reflects not just a target chemical structure, but a set of lived choices about sourcing, handling, storage, and support. The difference between CMPPA and similar options lies less in a few technical parameters than in the reliability of the process and the mindset of those who produce it. Those lessons may not always win awards, but they do drive progress, both for us and for every partner who stakes a harvest or a research outcome on our work.