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HS Code |
180413 |
| Chemical Name | 2-(3-Hydroxyphenyl)ethylamine |
| Molecular Formula | C8H11NO |
| Molecular Weight | 137.18 g/mol |
| Cas Number | 421-67-6 |
| Appearance | White to off-white solid |
| Melting Point | 77-80°C |
| Boiling Point | 285°C |
| Solubility | Soluble in water and polar organic solvents |
| Density | 1.145 g/cm³ |
| Pka | 9.32 |
| Smiles | CC1=CC(=CC=C1O)N |
| Inchi | InChI=1S/C8H11NO/c9-6-5-7-2-1-3-8(10)4-7/h1-4,10H,5-6,9H2 |
| Synonyms | m-Tyramine |
| Storage Conditions | Store at room temperature, protected from light and moisture |
| Hazard Statements | May cause irritation to skin, eyes, and respiratory tract |
As an accredited 2-(3-Hydroxyphenyl)Ethylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging contains 25 grams of 2-(3-Hydroxyphenyl)ethylamine in a sealed, amber glass bottle with a tamper-evident cap. |
| Shipping | 2-(3-Hydroxyphenyl)ethylamine is shipped in tightly sealed containers to prevent contamination and degradation. It should be stored and transported at controlled room temperature, away from heat, moisture, and direct sunlight. Proper labeling according to chemical safety regulations is ensured, and all handling complies with relevant hazardous material transport guidelines. |
| Storage | 2-(3-Hydroxyphenyl)ethylamine should be stored in a tightly sealed container, protected from light, moisture, and incompatible substances such as strong oxidizing agents. Store at room temperature in a cool, dry, and well-ventilated area, away from direct sunlight and ignition sources. Ensure that the storage area is clearly labeled and follow all applicable safety and regulatory guidelines for handling chemicals. |
Applications of 2-(3-Hydroxyphenyl)Ethylamine in Industrial Manufacturing2-(3-Hydroxyphenyl)Ethylamine is a specialized raw material that serves as a key intermediate in a range of high-value industrial manufacturing segments. As a direct manufacturer, we supply this material to sophisticated formulation lines where traceability, compliance, and functional consistency are strictly managed. Below, we detail real downstream application scenarios and provide specific technical data on compliance, quantitative usage, integration with existing production workflows, and final product archetypes. 1. Active Pharmaceutical Ingredient (API) Synthesis for Central Nervous System (CNS) AgentsThis compound functions as a building block for the synthesis of select CNS-active agents, particularly targeted monoamine analogs. Pharmaceutical intermediates use it at precise steps to ensure molecular integrity and compliance with regulated impurity profiles. The input batch must consistently meet stringent quality control benchmarks to ensure the final API performance in finished dosage forms. Adjustment of addition ratios depends on synthetic route yield targets and downstream purification protocols. Industry compliance standards
Typical usage ratio
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2. Dopaminergic Agent in Veterinary Feed Additives2-(3-Hydroxyphenyl)Ethylamine functions as a nutritional enhancer in specialized veterinary feed premixes designed for performance livestock. Its addition supports neurological health and feed conversion efficiency. Formulators weigh its inclusion based on requirements for metabolic stimulation and with careful control to remain inside regulated feed levels. Documentation ensures traceability for animal feed manufacturers supplying regulated export markets. Industry compliance standards
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3. Intermediate in the Synthesis of Specialty Dyes and PigmentsThis material is a cornerstone precursor in the production of certain catechol and hydroxyphenylethylamine-derived dyes prized in both textile and printing industries for their resistance properties and chromaticity. Colorant chemists select it based on compatibility with specific diazotization and coupling agents. Its metered introduction impacts both color intensity and downstream pigment processing characteristics, making raw material specification crucial for batch standardization. Industry compliance standards
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4. Fine Chemical Intermediate for Fragrance and Aroma ManufacturingIn aroma and perfumery chemical lines, our material participates as a precursor for the synthesis of tailored phenolic compounds that form the basis of unique olfactory notes. Its reliable input quality allows aroma engineers to achieve batch reproducibility, which is critical for branded fragrance formulations. Dosage tuning depends on desired fragrance intensity and the compatibility with downstream esterification or acetylation steps. Industry compliance standards
Typical usage ratio
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5. Biomedical Research Reagents for Neurochemical StudiesResearch laboratories utilize this material as a standardized neurochemical reference or as a synthetic reference for in vitro and in vivo experiments related to neurotransmitter mechanisms. Our quality control documentation supports advanced research where analyte stability and impurity profile critically impact experimental outcomes. Input amounts are carefully validated to match protocol-specific requirements and analytical calibration needs. Industry compliance standards
Typical usage ratio
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Competitive 2-(3-Hydroxyphenyl)Ethylamine prices that fit your budget—flexible terms and customized quotes for every order.
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Working in the chemical industry brings the value of precision to the forefront. 2-(3-Hydroxyphenyl)ethylamine, often called m-tyramine, isn't simply another entry on our product list. We've watched customers grow from small labs to large-scale operations with this compound at their side. Creating a product that remains consistent through every order takes more than well-maintained equipment and a clean facility—it takes a focus on every step, from raw material sourcing to the last verification before shipment.
2-(3-Hydroxyphenyl)ethylamine has the molecular formula C8H11NO and a molar mass close to 137.18 g/mol. Our standard lot features a white to pale beige crystalline powder, and we make every effort to keep the color and granule structure steady across each batch. Even a subtle change in appearance prompts internal review. Every production cycle comes with its own Certificate of Analysis, and the traceability record stays available for all shipments, which our clients in pharmaceuticals and research have come to rely on.
Our core specification for general use chemistry holds an assay above 98% by HPLC. The ash and heavy metal content stay controlled—levels sit well below established industrial risk thresholds. The water content depends on drying length, typically remaining under 0.5%. These checks ensure researchers, synthesis groups, and scaling engineers receive what we’d trust in our own pilot projects. Tighter specifications are possible too, and custom orders always bring a welcome challenge.
We work with 2-(3-Hydroxyphenyl)ethylamine more than any other substituted phenethylamine, and the reasons for its selection cut across fields. In pharmaceutical research, its backbone fits into the synthesis of adrenergic agents and dopamine analogues. Teams in neurochemistry request it for building neurotransmitter models. For fine chemical makers, it often acts as a key amine for further derivatization. Color developers and specialty dye makers lean on it for specific chromogenic effects that other phenylethylamines fall short of delivering.
Our product’s stability against air and moisture keeps issues in storage low, and we’ve seen it stand up to extended lab bench exposure. Some groups appreciate the lower melting point compared to para analogs, as it streamlines recrystallization or downstream processing, especially at modest scales. That lower melting point might look like a trivial number at first glance, but in a manufacturing setting it saves on energy and reduces process bottlenecks.
Plenty of customers start by asking “How does 2-(3-Hydroxyphenyl)ethylamine compare to its ortho and para isomers?” The answer feels clear after you’ve run both small-scale and plant-scale tests. In the meta position, the hydroxy group produces less interference during condensation and coupling reactions, so yield losses stay minimal. The para version, 2-(4-Hydroxyphenyl)ethylamine, sometimes gives higher basicity but brings bigger troubles with oxidation and byproduct color.
Our colleagues running bioassays note differences that shape their final choice. m-Tyramine runs with lower physiological activity than tyramine, so researchers aiming for selective action turn to our product as a starting point. In dye and pigment research, that same substitution pattern gives deeper shades and reliable permanence, which shifts preferences toward the meta isomer. We’ve listened to customers share surprises during chromatography—the elution patterns never perfectly match across isomers, so the purity checks for each batch must stay tailored.
Anyone evaluating a switch between 2-(3-Hydroxyphenyl)ethylamine and other phenylethylamines should know about downstream compatibility. This product’s compatibility with nucleophilic substitutions outpaces the ortho variant, and fewer side reactions have been documented during enzymatic transformation attempts. This advantage comes from the meta position’s infrequent involvement in side chain interference, and it saves both time and raw material costs for groups pushing their resources to scale.
Adapting to research trends is part of our work culture. Lately, higher-purity 2-(3-Hydroxyphenyl)ethylamine has been central to a handful of emerging research programs: neuroactive drug prototypes, fluorescent molecule development, and biochemical measurement tools. Customers trust our quality systems because we run multiple parallel assays—HPLC, GC-MS, and classical titration—all within the same quality assurance lab.
Some partners request microgram-level trace impurity screenings, as modern instrumentation now makes sub-ppm detection standard. Where ten years ago a loose margin sufficed, requests today tend toward rigorous, data-driven guarantees. Our team has responded by redesigning key reactors for improved air exclusion, and by working with suppliers who document every transport and handling checkpoint of starting phenols and ethylamines.
Opinions in the trade press sometimes linger on “premium” chemicals being just branding. Yet in practice, the stability, reliability, and transparency built into our 2-(3-Hydroxyphenyl)ethylamine distinguish it from bulk offerings. We’ve witnessed how an inconsistent product can stall multiple runs of research and waste budgets overnight. The resilience of our product has brought back clients who made brief attempts at sourcing cheaper options—real-world performance settles the matter.
We maintain our status as the genuine source because it gives customers critical benefits: price certainty, full traceability, and access to process data. While the broader market deals with countless intermediaries, we continue drawing material directly from our production reactors, handled by the same in-house crews who monitor and document every shift. Logistics staff prepare shipments right at the synthesis site, so no gaps appear in the chain of custody.
Direct production means unexpected questions about batch variation, synthetic precursors, or conversion yields get answered by hands-on technical staff, not by generic sales clerks. This proximity to manufacturing makes adjustments swift—a shift supervisor can implement equipment recalibration within hours, not days, after detecting new customer requirements. That responsiveness keeps us close to research groups trialing minor variants or scaling up promising process modifications.
Chemical producers run on trust earned over years, not big marketing spends. As 2-(3-Hydroxyphenyl)ethylamine remains in demand, our growth depends on never breaking that trust—transparency around solvent sourcing, trace metals, and final product quality keeps scrutiny satisfied from both clients and inspectors. Teams that run their own quality checks often partner with us on parallel-verification, strengthening the reliability chain.
The world no longer tolerates producers ignoring their environmental impact. For every kilo of 2-(3-Hydroxyphenyl)ethylamine dispatched from our facility, the solvent recycling records remain updated and available. We actively reduce halogenated waste, routinely exceeding the local region’s recovery targets. Switching reactor loads from classic solvent-heavy sequences to more atom-efficient approaches has trimmed both our energy bills and downstream waste handling expenses.
Clients focused on green chemistry have driven us to test biocatalytic routes and alternate phenol sources. Several pilot runs have involved plant-derived starting materials instead of the traditional fossil-based derivatives. While these methods haven’t fully replaced standard syntheses for the bulk of production, our R&D group keeps them under active evaluation, especially for custom requests or customers operating under strict environmental budgets.
We track our carbon footprint across every ton sent out, using meter-by-meter gas and electricity logging throughout each synthesis module. These measurements feed into our annual reports and inform the next round of process upgrades. Many customers in Europe and North America place sustainability criteria just behind purity and cost—so forward movement on green metrics has opened doors to new collaborations. For users exploring life cycle impact analyses, all data is shared up-front, without hedging or opacity.
As a production staff, we interact with this compound every day—so workplace safety isn’t negotiable. Our team emphasizes ventilated storage and rapid sealing of every batch, with humidity monitors in all local depots. 2-(3-Hydroxyphenyl)ethylamine doesn’t display extreme toxicity under normal handling, yet small mistakes can add up during round-the-clock plant runs. Gloves, filtration-grade masks, and splash-resistant aprons form our daily equipment, and operators complete quarterly review sessions for handling and first aid drills.
Shipping supervisors double-check fill weights and drum seals before dispatch. We store finished material in tightly closed HDPE drums or amber glass, and clients aiming for multi-year storage often consult us for stability studies. Post-delivery, our customer support team remains available for questions on safe handling, trace impurity testing, or repackaging for workflow optimization.
These are not hypothetical best practices—they come from daily production line experience. Our staff rotates through quality control labs, weighing rooms, reactor halls, and shipping bays, building familiarity with the material’s quirks. This on-the-ground knowledge shapes every decision, whether adjusting moisture control on a humid day or reviewing response procedures with a new hire.
For teams trialing new research reagents or scaling up an established product, getting quality and consistency right the first time matters more than promotional gloss. Feedback from end-users—along with data from performance tracking—feeds back to our process engineers and helps eliminate persistent issues that can, in other settings, drag on unresolved for weeks or even months. Direct reporting lines ensure plant operators and senior managers see the same customer data.
No batch leaves our hands without review. Reports from standard analytics—content, purity, micron-scale particulate presence—align with customer feedback and published literature. Variance triggers review, not rationalization. Our longstanding relationships with instrument makers keep our labs current, and we recalibrate in-house sensors as often as necessary instead of relying solely on schedule.
We support research groups aiming to push 2-(3-Hydroxyphenyl)ethylamine’s applications further. Some have published on biomarker discovery; others in new fluorescent labeling strategies. These collaborations give us an early look at shifting purity, solubility, or stability demands, and we don’t hesitate to introduce post-synthesis purification upgrades where the evidence points.
Input on missed delivery windows or supply chain hiccups gets fast response—root cause assessments, not excuses, follow. It’s not only about today’s batch, but every batch that follows for years. That reliability shapes long-term growth more deeply than flashy advertising or price-led competition.
2-(3-Hydroxyphenyl)ethylamine never stops opening new doors in synthesis and research. Our commitment means keeping one eye on technical evolution—expanded chiral resolutions, enantioselective routes, or niche applications in sensor chemistry—while delivering on today’s deadlines and budgets. We draw talent from process engineering, academic labs, and hands-on production roles to keep pace with shifting research and market needs.
As expectations move toward better sustainability, transparency, and value, only genuine manufacturers with skin in the game can keep chemical innovation moving forward. Partnerships thrive when trust meets data, process control meets flexibility, and promises meet reality. This approach is how we’ve managed to stand behind our 2-(3-Hydroxyphenyl)ethylamine for years, always ready to do better, batch after batch.