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HS Code |
959458 |
| Cas Number | 4386-55-6 |
| Molecular Formula | C9H11NO2 |
| Molecular Weight | 165.19 g/mol |
| Iupac Name | 2,3-dihydro-1,4-benzodioxin-6-ylmethanamine |
| Smiles | NCC1=CC2=C(C=C1)OCCO2 |
| Appearance | Solid |
| Melting Point | 46-50 °C |
| Purity | Typically >98% |
| Storage Temperature | 2-8°C |
| Synonyms | 6-(Aminomethyl)-2,3-dihydro-1,4-benzodioxin |
| Chemical Class | Benzodioxane derivative |
As an accredited 2,3-Dihydro-1,4-Benzodioxin-6-Ylmethylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White, opaque screw-cap bottle labeled “2,3-Dihydro-1,4-Benzodioxin-6-Ylmethylamine, 25g” with hazard symbols and lot number printed. |
| Shipping | 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine is shipped in tightly sealed, chemical-resistant containers, protected from light and moisture. It is transported according to relevant local, national, and international regulations for laboratory chemicals, with clear labeling and documentation. Standard shipping precautions for amines and aromatic compounds are observed to ensure safe delivery. |
| Storage | 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible substances such as strong oxidizing agents. Store at room temperature, protected from moisture. Handle with care, using appropriate personal protective equipment, and follow all relevant safety guidelines to prevent contamination or accidental release. |
Applications of 2,3-Dihydro-1,4-Benzodioxin-6-Ylmethylamine in Industrial ManufacturingAs a dedicated producer of 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine, we support a defined range of advanced sectors with this specialty chemical. Its application is based on strict compliance, quality standards, and close integration into downstream production workflows, leading to specific end-use products in pharmaceuticals, agrochemicals, fine chemical synthesis, and advanced polymer intermediates. 1. Pharmaceutical Intermediate for CNS Agent SynthesisOur material serves as a key intermediate in the multi-step synthesis of central nervous system (CNS) active compounds, particularly targeting substituted benzodioxin scaffolds used in antidepressant and anxiolytic drug production. Pharmaceutical companies utilize it at early and mid-stages under GMP conditions to precisely control active pharmaceutical ingredient development and yield high-purity bases for final formulation. Industry compliance standards
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2. Agrochemical Active Compound PrecursorResearchers and commercial agrochemical plants use this compound as a selective amine source to retrofit new-generation crop protection molecules, particularly in the synthesis of fungicidal and insecticidal actives based on benzodioxin-core scaffolds. Its high purity boosts predictable reactivity and downstream stability of final molecules in formulated crop protection agents. Industry compliance standards
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3. Specialty Fine Chemical Building BlockProducers of fine and performance chemicals rely on this compound for introducing benzodioxin-linked amine functionalities into photoinitiators, UV absorbers, and specialty reactive dyes. Its stable and clean reactivity lends high batch-to-batch reproducibility essential for small-volume, value-added synthesis in precision chemical lines. Industry compliance standards
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4. Advanced Polymer Modification AgentManufacturers engineer this intermediate into the main chain or as a pendant group in advanced functional polymers, such as conductive polymers for electronics or membrane materials used in separation technologies. Its amine functionality permits selective grafting and post-polymerization modification, granting tailored physical and chemical properties to the final polymer system. Industry compliance standards
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For years, the push in fine chemicals and pharmaceutical intermediates has called for deeper technical know-how and relentless quality monitoring. 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine is a prime example of how this mentality shapes real-world production. This compound stands out for both its structural reliability and its versatility. Our plant teams have worked long shifts perfecting every step from raw ingredient purification to final packaging, because we know sharp attention to detail separates dependable batches from troubled ones.
The chemical structure of 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine delivers consistent performance where precision matters. Its core, shaped by the fused benzodioxin and methylamine groups, helps chemists build more complex analogs, making it valuable during the design of targeted therapies or specialty materials. In our operations, consistency doesn’t begin at filling drums — it starts with upstream selecting of reagents and calibrating reactors. Small adjustments in temperature or solvent quality show up in lab results more than paperwork ever will.
Our customers usually walk in with targeted projects. Over the past years, most demand for this amine variant comes from pharmaceutical research divisions and material science labs. Researchers choose this molecule as a practical intermediate when building scaffolds that mimic natural products or in prototyping candidates for neurological or oncological applications. We’ve personally followed up with project teams down the chain, hearing firsthand how downstream reactions benefit from the molecule’s reactivity profile. No off-odors, fewer side impurities: the actual outcomes speak louder than specification sheets.
Every kilogram shipped carries its history. Most sites making this product worldwide stop after basic purification. Our process pushes further, monitoring for trace aldehyde and chloride impurities, and cross-checking chiral purity when required. Many clients tell us their reactions run smoother, and yields go up when switching over. They aren’t just looking for pure material by the numbers—they want predictability. Project timelines shrink as a result.
Chemically, 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine sets itself apart from similar amines with its unique fused ring. Competitors sometimes substitute basic benzylic amines, but those alternatives often produce more decomposition under standard lab stresses. In head-to-head testing, our own process chemists have seen improved catalyst compatibility with this compound compared to basic phenethylamines or simple methylamines. From synthesis of advanced building blocks to late-stage functionalization, reaction pathways tolerate harsher conditions without derailing.
We see questions come up from clients scaling up reactions for the first time. Handling bulk amine batches brings challenges—stability upon storage, reactivity to moisture, and long-term performance drift. After multiple years tracking batch outcomes, our team responds with practical guidelines for solvent choice, container material, and best handling practices. Absent these steps, competitors often report product browning or loss of activity, creating roadblocks for pilot and manufacturing scale-up.
Quality routines at the production site run more than just box-ticking. Our technicians run both routine and random sampling: every drum passes through NMR, GC-MS, water content analysis, and optical rotation checks (if used for chiral synthesis). Trace by-products, such as minor ring-opened species or unreacted amines, get flagged right away. This vigilance comes from long experience. We've had years when slight changes in reactor temperature as low as 2 degrees made the difference between a flawless batch and wasted work—a fact learned not from manuals, but from costly reruns and customer calls.
One of our earliest challenges: scaling from a 2-liter Schlenk flask to 500-liter reactors. Many production hiccups only reveal themselves at scale; heat transfer, reagent metering, and agitation become far less forgiving. In the early days, we saw critical batches risk runaway exothermic reactions, or unpredicted by-product formation from subtle contaminant residues. Now, every time we increase production volumes, troubleshooting protocols run in parallel with synthesis, not after. The hard lessons carry forward into every lot.
Safety earns its place front and center in every shift briefing. 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine, like many amines, reacts with acids, oxidizers, and must be kept dry. A cavalier approach guarantees lab incidents—so the protocols in place reflect real-life scenarios from our own plant: spills, vapor containment, and staff exposure. Routine onsite training, real mock drills, and periodic review of procedures anchor our safety record. Customers trust a material more when the supplier’s own teams are protected by that same material handling philosophy.
Regulatory and environmental standards aren’t just external targets. Every molecule leaving our gate represents a choice about solvent use, waste stream minimization, and resource conservation. Over the past five years, we overhauled our amine production to lower solvent emissions, recycle water, and reduce the weight of packaging without undermining product safety. Our aim: fewer hazardous residues, lower disposal costs for our clients, and a smaller carbon footprint per kilogram delivered.
We don’t operate in a vacuum. Customers return again and again with questions, concerns, and stories about their own downstream hiccups. These reports shape our QC routines—they don’t just fade into post-sale silence. One of the biggest shifts in our practice happened after a pharmaceutical customer pointed out marginally inconsistent melting points, leading us to revisit an overlooked filtration step. Iterative problem-solving lies at the heart of reliable fine chemical production.
Lab-to-lab variation shows up in the details: water content, trace ion presence, and color stability. Too much residual solvent, a slight tinge of yellow instead of bright white—these small factors can stop a downstream reaction in its tracks. Our plant has invested heavily in in-process controls, such as real-time spectrometric checks and automated dosing regimes, to lock down these factors before a misstep can propagate through several tons of inventory. Years of feedback honed these methods, shaving down batch failures and keeping performance at the level our clients expect.
Compliance matters in every global market, but navigating ever-changing documentation and third-party audits takes more than copying paperwork templates. We put full-time resources into maintaining up-to-date protocols, and senior staff participate in reviews of international standards. Having ready data packages and clear, verifiable traceability means our customers move through their own regulatory submissions more smoothly—and if a rarely asked question crops up, we can answer it from experience, not guesswork or deflection.
Buying 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine from a manufacturer should bring access to real technical support. Our engagement doesn’t stop at shipping; we troubleshoot with clients hands-on, dissecting failed syntheses, tweaking storage protocols, and sharing knowledge about specialized applications. Face-to-face on-site visits, video walk-throughs of lab setups, and open access to experienced production chemists form the backbone of our after-sales support. Projects progress faster when obstacles get cleared through dialogue, not canned advice.
Some suppliers tout ultra-high specifications, but we learned long ago that measured results from actual reactions matter more than paperwork promises. Our team occasionally runs competitive comparisons in model pharmaceutical reactions, publishing the findings and discussing how real-world factors like foaming, solubility, and catalyst compatibility play out. These transparency efforts let customers trust their decisions: they see actual traceability, not just claims.
Requests from partners and academic labs often set the agenda for future product refinements. Periodic investments in process chemistry allow us to develop new variants, adjust crystal morphology, or tailor particle size for special needs. This hands-on collaboration with researchers means more than just another checkbox in a product portfolio—it brings fresh challenges and fresh solutions, spurring us to innovate in sample dispatch, documentation, and batch reproducibility.
Building chemicals to spec and shipping them out doesn't capture the full picture. Direct relationships with end users—be they academic groups pushing drug discovery forward, or technical teams improving material properties—create feedback loops that elevate the standard for quality. Dry technical specs rarely flag the real stumbling blocks: our open communication culture shortens the distance between plant floor and bench scientist, making every batch better than the last.
Quality and innovation in fine chemicals stem from hard-earned experience, an unblinking focus on measurement, and a willingness to adapt. The daily grind of plant operation—analyzing samples, running pilot batches, collaborating with end users—keeps our understanding honest. We rely on facts, not jargon, and stay anchored to straightforward principles that have fueled our progress in manufacturing 2,3-Dihydro-1,4-Benzodioxin-6-ylmethylamine. As new applications emerge, our close collaboration with scientists and manufacturers worldwide keeps the improvements flowing—not through abstract pronouncements, but through the proof measured in every delivered batch.