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2,3-Diethylpyrazine

    • Product Name 2,3-Diethylpyrazine
    • Alias 2,3-Diethyl-1,4-diazine
    • Einecs 207-050-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    195634

    Name 2,3-Diethylpyrazine
    Cas Number 15707-23-0
    Molecular Formula C8H12N2
    Molecular Weight 136.19
    Appearance Colorless to pale yellow liquid
    Boiling Point 198-200 °C
    Density 0.981 g/cm3
    Refractive Index 1.502
    Flash Point 87 °C
    Smell Nutty, roasted, pyrazine-like
    Solubility Slightly soluble in water
    Pubchem Cid 22572
    Inchi InChI=1S/C8H12N2/c1-3-7-6-9-5-8(4-2)10-7/h5-6H,3-4H2,1-2H3

    As an accredited 2,3-Diethylpyrazine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100g amber glass bottle with a secure screw cap, labeled "2,3-Diethylpyrazine, ≥98%," including safety and hazard information.
    Shipping 2,3-Diethylpyrazine is typically shipped in tightly sealed chemical containers to prevent leaks and contamination. It requires cool, dry conditions, with limited exposure to light and air. Keep away from strong oxidizers. Shipping must adhere to relevant regulations and safety standards for handling organic chemicals, including proper labeling and documentation.
    Storage 2,3-Diethylpyrazine should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible substances such as strong oxidizers. Keep it away from sources of ignition, heat, and open flames. Clearly label the storage container, and follow all standard safety protocols, including proper personal protective equipment (PPE) when handling.
    Application of 2,3-Diethylpyrazine

    Applications of 2,3-Diethylpyrazine in Industrial Manufacturing

    2,3-Diethylpyrazine serves as a high-value aroma compound with specific performance in sensory-enhancement and chemical synthesis across flavor, fragrance, tobacco processing, and specialty food industries. As the direct manufacturer, we support a transparent supply chain for B2B partners requiring strict regulatory compliance and consistent formulation performance. Below, we detail authentic use scenarios, integration points, and regulatory frameworks for this ingredient.

    1. Savory Food Seasoning Production

    2,3-Diethylpyrazine delivers nutty, roasted, and meaty flavor notes prized in processed seasonings for instant noodles, snack blends, and ready-to-eat meals. Industrial culinary formulators dose it precisely in composite flavor bases after initial Maillard reaction flavor development, enhancing the product’s depth and authenticity. Its low odor threshold demands careful handling to meet both taste and legal limits for food-safe ingredients.

    Industry compliance standards

    • GB 2760-2024 (China Food Additive Standard)
    • 9 CFR Part 172.515 (FDA Flavouring Substances)
    • EU Commission Regulation (EU) No 1334/2008 on flavourings and certain food ingredients
    • JECFA: Joint FAO/WHO Expert Committee on Food Additives evaluation

    Typical usage ratio

    • 0.01–0.08 ppm in total seasoning mass, depending on intensity of base formula and flavor complexity
    • Adjustments made based on sensory panel evaluations and country-specific flavor limits

    Downstream process integration

    • Added post-Maillard reaction, dissolved in carrier solvent before final blending of seasoning powder or paste
    • Incorporated during flavor top-notes addition to avoid thermal loss
    • Direct dosing into spray-dried, freeze-dried, or liquid flavor systems

    Final product types

    • Instant noodle soup bases
    • Roasted nut seasoning blends
    • Processed meat marinades and rubs
    • Vegetarian/vegan savory bouillon cubes

    2. Tobacco and Heated Tobacco Product Manufacturing

    Manufacturers in fine-cut, reconstituted, and heated tobacco sectors leverage 2,3-Diethylpyrazine to simulate warm, roasted, and cocoa-like undertones that naturally develop in cured tobacco leaves. This compound enters formulation at trace levels as part of top flavor systems post-leaf processing, providing both aroma lift and masking of undesirable notes.

    Industry compliance standards

    • ISO 12863 (Cigarettes – Standardized analytical regime)
    • US FDA Premarket Tobacco Product Application (PMTA, ingredient disclosure)
    • EU Tobacco Product Directive 2014/40/EU (Ingredient reporting)
    • China Tobacco Monopoly Administration Additive Catalogue (食品添加剂 catalog alignment)

    Typical usage ratio

    • 0.5–5 ppm (by dry tobacco mass), adjusted per blend type and base tobacco aroma strength
    • Final dosage controlled through GC-MS trace analysis and finished product sensory validation

    Downstream process integration

    • Added to casing and flavoring baths after primary leaf processing
    • Co-blended in master top-aroma systems for reconstituted tobacco sheets
    • Injected or sprayed onto cut tobacco shreds before final drying and packing

    Final product types

    • Manufactured cigarettes
    • Heat-not-burn tobacco sticks
    • Pipe tobacco and cigar blends
    • Tobacco sheet or film products for oral use

    3. Processed Nut and Snack Flavoring

    For producers of roasted nut snacks and savory cereals, 2,3-Diethylpyrazine introduces pronounced roasted and caramelized nuances, amplifying or simulating authentic roast flavors when applied to otherwise bland base materials. It enters the spray-coating or seasoning tumbling stage for uniform application and aroma performance, with careful batch QC to maintain compliant residual levels.

    Industry compliance standards

    • 21 CFR 172.515 (FDA Flavoring Substances Permitted for Direct Addition to Food)
    • EFSA Guidance on Flavouring Evaluation
    • FSSC 22000 (Food Safety System Certification for flavor facilities)
    • GMP (Good Manufacturing Practice, flavor compounding)

    Typical usage ratio

    • 0.03–0.12 ppm in seasoning matrix, based on desired roasted profile and substrate absorption
    • Lowered in oil-roasted applications due to fat-soluble retention

    Downstream process integration

    • Blended with liquid or encapsulated flavor premix prior to application on roasted nuts or cereal pieces
    • Introduced as part of post-baking or post-roasting treatments in industrial rotary tumble drums

    Final product types

    • Roasted and flavored peanuts
    • Savory trail mix components
    • Baked protein snacks and chickpea crisps
    • Breakfast cereal with honey-roast or caramelized profiles

    4. Pet Food Palatant and Flavor Base Manufacturing

    Pet food flavor suppliers use 2,3-Diethylpyrazine to improve aroma acceptance and feeding attraction in meat-based and vegetarian formulas. The compound gets dosed into palatant premixes that undergo spray-cooling or dry blending just prior to final extrusion or coating, guaranteeing homogenous distribution and shelf-stable aroma release, with active control of carry-over and cross-contamination risks in GMP facilities.

    Industry compliance standards

    • AAFCO Official Publication (American Association of Feed Control Officials, flavor ingredient listing)
    • FDA 21 CFR 573.860 (Feed Additives and GRAS status check)
    • FAMI-QS (European Feed Additives and Premixture Quality System)
    • ISO 22000 (Food Safety Management System for feed and flavor plants)

    Typical usage ratio

    • 0.03–0.09 ppm in total palatant blend; optimized with palatability testing across species and formula
    • Tight upper thresholds set for premium and organic feed lines

    Downstream process integration

    • Introduced at wet mixing or pre-conditioning stage for palatant slurry production
    • Dry blended into thermally treated powdered flavor bases for direct spray application onto extruded kibbles

    Final product types

    • Coated kibbles for cat and dog dry food
    • Canned pet food with grilled or roasted character
    • High-protein pet treats
    • Companion animal supplements targeting palatability improvement
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    Certification & Compliance
    More Introduction

    2,3-Diethylpyrazine: An Overview from the Production Floor

    Introduction to 2,3-Diethylpyrazine

    At our plant, 2,3-Diethylpyrazine consistently draws interest from customers across flavor and fragrance manufacturing, fine chemicals, and specialized research. Every day, the complex aroma reminds us why this compound endures in demand, even as trends come and go. With a molecular formula of C8H12N2 and a distinctive nutty character, its impact reaches well beyond the laboratory.

    Understanding Our Model and Specifications

    The model we produce stands out for its purity and quality control. Each batch undergoes rigorous chromatographic analysis, achieving a purity that meets the strict benchmarks required in food-grade and pharma-adjacent applications. Typical deliveries contain less than 0.5% moisture by Karl Fischer titration and minimal side-pyrazine content. Targeted production yields a clear, pale liquid, free from particulate, designed for ease of handling in both automated and manual metering systems. Gas chromatography profiles confirm our adherence to regulatory and voluntary standards, particularly for customers in regulated markets.

    As chemical manufacturers, we structure our offerings for direct incorporation into production lines. Standard drums and high-integrity IBC totes provide secure storage and transport, while smaller laboratory quantities see vacuum-sealed containers for uncompromised stability. Our technical staff conducts validation on every production lot, referencing historic outcomes and root-cause analysis when deviations emerge. This approach minimizes surprises for end users and assures downstream blending and formulation meet expectations.

    Where 2,3-Diethylpyrazine Matters Most

    Having worked alongside formulators in the flavor industry, I have watched 2,3-Diethylpyrazine take an unshakeable place in the recreations of roasted notes and nut flavors. Its ability to evoke the warmth of roasted coffee or peanuts never feels artificial when used with restraint. In the fragrance world, it lends a recognizably toasted undertone that supports deeper, woodsy chords. As consumer preferences evolve, regulatory scrutiny on flavor additives intensifies, but the established safety profile of 2,3-Diethylpyrazine continues to support its use at controlled levels. Our decade-long presence in the supply chain means we stay updated on FSSC 22000, ISO 9001, and any evolving compliance standards.

    Beyond sensorial properties, research has pointed to functions in analytical chemistry and as intermediates for further synthesis. Many chemists have used pyrazine derivatives for their nitrogen-donating properties, and our customers in pharmaceutical R&D have explored 2,3-diethyl variants as core building blocks. In these cases, lot-to-lot consistency and access to technical documentation become as critical as the molecule itself.

    Distinctiveness Compared to Other Pyrazines

    Working directly with pyrazine derivatives since the 1990s, I have seen how subtle modifications, even a shift from di-ethyl to di-methyl substitution, create a cascade of effects in aromatic signature and volatility. 2,3-Diethylpyrazine delivers a softer, toastier note than its more austere methyl analogues. Unlike 2,6- or 2,5-variants, which often play best in background roles, the 2,3 arrangement brings a more assertive profile, giving formulators a unique lever to pull. At the bench, the boiling point and handling characteristics sometimes challenge existing protocols, but a consistent raw material addresses most concerns. Overall, it resists the harshness that sometimes accompanies alkyl-substituted pyrazines while delivering the flexibility required in modern food and fragrance creation.

    In comparison with simpler pyrazines, the di-ethyl side groups enhance hydrophobicity and slightly suppress volatility, giving longer retention in finished products. This nuance is essential in finished goods, where fleeting or overpowering effects must be avoided. The ethyl groups, carefully chosen, also reduce threshold concentrations, allowing formulators to work with lower inclusion rates and tighter cost control. From our perspective, this translates into less material waste, more efficient batch conversions, and customer loyalty reinforced on trust instead of price alone.

    Manufacturing Insights: From Raw Materials to Finished Goods

    Every batch of 2,3-Diethylpyrazine starts with meticulous raw material vetting. Over decades, we have built relationships with upstream suppliers of ethyl-substituted diamines and nitrogen sources, visiting plants and evaluating reactors firsthand. We audit for trace contaminants, tracing sources for any deviations. Our reactors, outfitted with corrosion-resistant linings, handle the sometimes caustic intermediates required for high-purity pyrazines. Technicians monitor each phase, carefully adjusting parameters to steer clear of unwanted isomer formation. Reactivity curves, refined by real world troubleshooting, steer our schedules and minimize downtime.

    Once synthesized, each lot enters a dedicated suite for purification. Fractional distillation and solvent exchange cycles remove process byproducts, followed by vacuum drying for maximum stability. Since 2,3-Diethylpyrazine readily absorbs ambient moisture, we maintain strict controls on air quality and storage temperature throughout filling operations. Samples drawn mid-run undergo full spectrum analysis, a practice we developed after early trial runs yielded surprises we would prefer not to repeat. Our warehouse and logistics staff remain in close contact with downstream partners to align shipment schedules with actual process windows, avoiding double-handling that might compromise the integrity of this sensitive product.

    Quality, Safety, and Responsibility

    Quality and safety cannot be separated from responsibility in chemical manufacturing. Long before quality systems became mandatory, we found that hands-on training, clear documentation, and open lines of communication with customers proved more valuable than any paperwork or certification alone. Recurring audits from flavor houses and pharmaceutical partners demonstrate that transparency on our production floor builds credibility in the wider market. When rare non-conformances happen, our quality team investigates rapidly, drawing on both digital process records and the tacit knowledge of line operators. We review every issue, from minor specification drifts to potential contaminant incursions, and use findings to tune our processes and prevent recurrence.

    The unique safety profile of 2,3-Diethylpyrazine means we rarely face acute health or environmental incidents, provided we respect established handling precautions. Our EHS protocols, integrating lessons from past industry events, emphasize source control to avoid unnecessary exposure. Each time we review material safety data, I check not just for compliance, but for practical application on the floor—personal protection, ventilation, and spill response training receive just as much attention as compliance documentation. We also encourage our partners, through joint site visits and shared best practices, to maintain vigilance at every stage from receipt through final product application.

    Addressing Industry Challenges: Continuity in a Changing Market

    Industry trends often disrupt established supply chains, but stability matters. The volatility in logistics, whether from geopolitics, freight cost spikes, or local regulatory changes, can threaten on-time delivery and price predictability. We counteract these shifts by maintaining buffer stocks of both 2,3-Diethylpyrazine and key raw materials. Advanced forecasting tools and real-time communications with both suppliers and customers allow us to anticipate disruptions before they impact critical orders. This approach has cushioned our partners from the effects of vessel delays, closed ports, and raw material rationing that otherwise would shut down flavor or research lines.

    Our investments in local and regional warehousing offer redundancy that global traders often overlook. Since flavor and fine chemical blenders face their own storage constraints, we coordinate just-in-time shipments and consignment arrangements that keep inventory risk and obsolescence to a minimum. These pragmatic solutions smooth over market rough patches, a lesson learned after years watching smaller competitors wash out of the business after unexpected shocks. Customers depend on certainty as much as they depend on price or technical specifications, and our ability to deliver on both fronts builds lasting partnerships.

    Supply Chain Transparency: The Manufacturer’s Perspective

    Traceability no longer carries future promise—it solves real-world challenges right now. For 2,3-Diethylpyrazine, end users request evidence of secure sourcing, ethical labor, and authentic batch traceability. We map our own supply chain, not through checkbox exercises, but through regular supplier visits, deeper audits, and full access to documentation across all levels. Every drum carries a scannable code linking to its production record, starting from raw material reception through final packaging and outbound shipment. This approach reassures food and fragrance partners facing rigorous third-party audits or increasing consumer demands for ingredient disclosure.

    We practice what regulators and NGOs require: certificates of analysis, chain-of-custody records, and sustainability declarations flow openly, not reactively. Our daily routines involve spot checks and breakdowns of supplier performance, including on-time delivery, non-conformance rates, and audit outcomes. Product recalls remain rare, but our structured protocols, developed in cooperation with downstream laboratories, enable immediate response, limiting exposure and liability on both sides of the transaction.

    Intellectual Property and Regulatory Compliance

    Competition encourages innovation, and strong intellectual property protection guarantees a return on years of technical development. Our synthesis routes for 2,3-Diethylpyrazine evolved from classic methods, now refined to maximize yield, minimize environmental footprint, and eliminate process steps subject to patent encroachment. We monitor patent landscapes, not just to stay clear of third-party protection, but to ensure we contribute original value. Our regulatory department tracks international hazard classification changes, reporting obligations, and evolving standards for flavor substances, so downstream clients can rely on up-to-date compliance information included with every shipment.

    Compliance failures carry steep penalties and take years to repair. Our approach involves direct engagement with regulatory bodies, participation in industry working groups, and targeted internal audits. We share findings from regulatory updates with our customers, helping them prepare product registrations, safety cases, or customs filings. Open communication eliminates misunderstandings and supports smooth product flows across borders, a ready advantage as cross-jurisdictional rules tighten around specialty chemicals.

    Sustainability and Process Optimization

    Legacy manufacturers have a responsibility to balance efficiency with sustainability. Over the years, we have redesigned aspects of 2,3-Diethylpyrazine production: from closed-loop solvent recovery to improved waste heat utilization, our goal is clear—reduce both carbon footprint and resource intensity. Our process engineers consult both peer-reviewed literature and on-the-ground operators to squeeze every increment of efficiency from batch scheduling and utility usage. As a result, our wastewater generation per metric ton of output tracks well below industry averages, reducing both environmental and compliance risk.

    Customers increasingly request lifecycle data and carbon accounting for their ingredients. We supply detailed environmental impact assessments, including Scope 1 and 2 emissions, allowing downstream partners to align our product with their own environmental goals. Sustainability extends beyond regulatory minimums. It means streamlining transportation routes, switching to lower-carbon packaging materials, and supporting local community initiatives that mitigate indirect effects of chemical manufacturing. These incremental changes, while never showy, endure as part of how we do business.

    End-User Feedback and Continuous Improvement

    Experience in the industry has taught that the sharpest insights often come from customers using 2,3-Diethylpyrazine in real-world applications. Technical feedback loops run deep—whether it is a flavorist seeking a subtlety in roasted nutty profiles, or a process engineer chasing a tighter specification for a pharmaceutical intermediate. These conversations identify opportunities for process refinement on our end. Small, iterative improvements, such as reduced impurity drifts or optimized packaging sizes, often stem from these partnerships.

    Customer site visits and collaborative trials allow us to gather application data beyond what laboratory trials reveal. Real-world production lines expose differences in product performance that rarely surface in controlled environments. Over time, our technical and sales teams have built enough domain knowledge to offer proactive support and troubleshooting, extending the value of our 2,3-Diethylpyrazine beyond the shipment itself. Giving end users both the product and relevant application insights enables both sides to succeed. Openness and humility guide these interactions, as each question or complaint brings new lessons to improve quality, logistics, or support services.

    Future Trends and Market Outlook

    As consumer awareness grows around ingredient authenticity, so too does demand for reliable, traceable, and compliant inputs. 2,3-Diethylpyrazine, as a tried and trusted tool in the formulation toolkit, faces challenges from new substitutes, synthetic biology, and evolving consumer expectations. Yet its enduring role, particularly in premium flavor development and advanced chemical synthesis, remains secure so long as manufacturers invest in both quality and transparency. Advances in green chemistry may soon shift particular synthesis steps away from legacy practices toward more enzyme-catalyzed or biomimetic approaches. We actively scout such opportunities while vetting new feedstocks and maintaining backward compatibility with established applications.

    The market outlook for 2,3-Diethylpyrazine, informed by direct engagement with formulators and buyers, indicates stable growth as emerging markets upgrade their food and fragrance capabilities. Tighter regulatory frameworks in developed economies add both complexity and opportunity for manufacturers who demonstrate good stewardship and compliance readiness. The intersection of supply chain innovation, end-user demand, and evolving best practices will continue to drive both risk and opportunity for those working closest to the molecule.

    Conclusion: Value Beyond the Molecule

    Through decades of hands-on manufacturing, 2,3-Diethylpyrazine has shown that its true value lies not just in its chemical structure, but in the expertise and integrity behind its production. We see every order as an extension of relationships built on trust, transparency, and continuous effort to improve. The challenges faced—whether technical, regulatory, or market based—are best met by listening to our partners and drawing upon both time-tested practices and new technologies. By respecting these principles, we aim to ensure that 2,3-Diethylpyrazine continues to deliver reliability, safety, and creative potential to every corner of the industries it serves.