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2,3-Dichlorotoluene

    • Product Name 2,3-Dichlorotoluene
    • Alias 1,3-Dichlorotoluene
    • Einecs 209-984-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    496555

    Cas Number o91-94-4
    Molecular Formula C7H6Cl2
    Molar Mass 161.03 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 208-210 °C
    Melting Point -11 °C
    Density 1.28 g/cm³ at 20 °C
    Refractive Index 1.548 at 20 °C
    Flash Point 85 °C (closed cup)
    Vapor Pressure 0.23 mmHg at 25 °C

    As an accredited 2,3-Dichlorotoluene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 500 mL of 2,3-Dichlorotoluene, with a tightly sealed cap and hazard labeling for safe handling.
    Shipping 2,3-Dichlorotoluene should be shipped in tightly sealed containers clearly labeled as hazardous. It must be handled according to local, national, and international regulations for flammable and toxic liquids. Protect from heat, sparks, and open flames. Transport with compatible materials, using appropriate safety measures and documentation to ensure safe delivery.
    Storage 2,3-Dichlorotoluene should be stored in a tightly closed container, in a cool, dry, well-ventilated area away from direct sunlight, heat, and sources of ignition. Keep away from strong oxidizing agents and incompatible chemicals. Store at room temperature and ensure proper labeling. Use secondary containment to prevent leaks or spills and install fume extraction where handled frequently.
    Application of 2,3-Dichlorotoluene

    Applications of 2,3-Dichlorotoluene in Industrial Manufacturing

    We produce 2,3-Dichlorotoluene for specialized industrial users with strict compliance, formulation, and integration needs. Below are detailed applications across key downstream sectors utilizing this raw material in high-value manufacturing chains.

    1. Agrochemical Intermediate Synthesis

    Major agrochemical companies use 2,3-Dichlorotoluene as a building block for synthesizing herbicide and fungicide actives. This material enables selective chlorination patterns essential for superior biological performance. Technicians typically employ it in multi-stage condensation or coupling reactions, followed by further halogenation or nitration. Strict plant hygiene and traceability apply at each batch, especially for products destined for regulated markets. Reliable analytical controls validate purity and byproduct levels before downstream formulation.

    Industry compliance standards

    • EU Regulation (EC) No 1107/2009
    • US EPA FIFRA Registration Process
    • China GB 2763 Maximum Residue Limits (for intermediates)
    • ISO 9001:2015 Quality Management Systems

    Typical usage ratio

    • 40–70% as core intermediate in target active synthesis pathway, varying by end molecule structure
    • Adjusted for yield optimization and impurity management in pilot plant and commercial scale

    Downstream process integration

    • Stage-one feedstock for high-pressure alkylation or chlorosulfonation units
    • Precursor in catalytic coupling with amines, phenols, or nitriles
    • Input to isolation, purification, and crystallization steps for active ingredient production

    Final product types

    • Herbicide active ingredients such as Dichlobenil derivatives
    • Fungicide actives for cereals, soy, and horticulture
    • Preparation of structural analogs for agrochemical R&D pipelines

    2. Pharmaceutical Intermediate Manufacturing

    2,3-Dichlorotoluene serves in API synthesis as a functionalized aromatic ring, allowing site-selective transformation to drug intermediates. Synthetic chemists favor its chlorine patterns for downstream functional group manipulation by metal-catalyzed amination, borylation, or Suzuki coupling. Rigorous cGMP operational controls govern all stages, including validated cleaning, documentation, and batch traceability. Analytical labs perform full residual solvent and impurity panels per ICH Q3A/B guidance prior to delivery into API lines.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA cGMP 21 CFR Parts 210 & 211
    • EU GMP Annex 8 (API intermediates)
    • USP, EP, or ChP monographs for final APIs

    Typical usage ratio

    • 25–55% as core intermediate input by molar stoichiometry, depending on downstream API synthetic route
    • Adjusted to minimize byproducts during functionalization and maintain control over isomer content

    Downstream process integration

    • Starting material for stepwise halogen-lithium exchange or Grignard reactions
    • Entry point for palladium-catalyzed cross-coupling to assemble aryl or heterocyclic drug scaffolds
    • Purification via preparative chromatography before API route continuation

    Final product types

    • Antihistamine or antipsychotic API intermediates (e.g., chlorinated benzylamines)
    • Synthetic precursors for oncology, CNS, and anti-infective agents
    • GMP-compliant final API intermediates for contract manufacturing supply chains

    3. Dye and Pigment Manufacturing

    Manufacturers in the colorant sector utilize 2,3-Dichlorotoluene as a specialty intermediate in azo dye and pigment molecule construction. Its dual chlorine atoms enable targeted electrophilic substitutions, which are critical for the synthesis of color-strong, lightfast pigments. Plants must operate in compliance with environmental emission norms owing to aryl halide handling. Integration is performed in closed-batch reactors where operators control temperature and catalyst loading for chromophore formation.

    Industry compliance standards

    • EU REACH Regulation (EC) No 1907/2006
    • US TSCA for aryl halide intermediates
    • ETAD Code of Practice for Colorant Additives
    • ISO 14001:2015 Environmental Management Systems

    Typical usage ratio

    • 30–65% in coupling reactions for azo intermediate synthesis, varies with shade intensity target
    • Proportion tailored to chromophore extension or substitution level required

    Downstream process integration

    • Charged to initial aromatic coupling step with diazonium salts or amines
    • Used in halogen substitution for tuning dye hue and resistance properties
    • Reacts in pressure reactors followed by isolation and drying into pigment granules

    Final product types

    • Solvent dyes for plastics, fibers, or coatings
    • Azo pigment intermediates for inkjet and flexographic inks
    • Lightfast pigments for automotive or industrial coating markets

    4. Specialty Polymer Modifier Production

    Leading polymer plants select 2,3-Dichlorotoluene to synthesize custom plastic additives and chain modifiers. Its chemical structure fits as a precursor for functional monomers and crosslinkers via nucleophilic substitution or partial oxidation. Strict QC labs monitor residual monomer and organochlorine profiles to align with product stewardship and polymer additive registration requirements. Integration typically occurs in controlled monomer drums or as part of the co-monomer stream.

    Industry compliance standards

    • EU Regulation (EC) No 10/2011 on Plastic Materials and Articles
    • US FDA 21 CFR 177 (indirect food additives—polymers)
    • ISO 11469 Plastics—Generic Identification and Marking
    • EN 71-3 Safety of Toys (as applicable for specialty coatings)

    Typical usage ratio

    • 5–20% of total monomer feed for functional polymer synthesis, depending on property modification goals
    • Adjusted based on targeted crosslink density and plasticizer compatibility

    Downstream process integration

    • Precursor in synthesis of aryl-functional comonomers for thermoplastics
    • Charged to reactor before polymerization initiation in bulk or solution phase
    • Intermediate in grafting or post-polymerization modification processes

    Final product types

    • Impact modifiers for engineering plastics (e.g., polystyrene blends)
    • Flame-retardant polymer additives
    • Specialty coatings and films for industrial applications
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    Certification & Compliance
    More Introduction

    2,3-Dichlorotoluene: Pure Quality, Consistent Results

    Understanding Our Approach to 2,3-Dichlorotoluene

    From the start, our work with 2,3-dichlorotoluene has centered on clear chemistry and reliable consistency. As a producer, we've built our processes to emphasize precision at every stage, from purification to packaging. Too often, supply chains introduce uncertainty. Because we manufacture at scale, we maintain direct control not just over raw inputs, but over the temperature, pressure, and mixing that define the final composition. For chemists, what goes unnoticed under ordinary lighting often emerges under scrutiny: impurities and trace differences that can affect downstream transformations. We’ve learned to focus on these subtleties.

    We offer 2,3-dichlorotoluene as a transparent, pale liquid, applicable across a spectrum from fine chemical synthesis to intermediates for active pharmaceutical ingredients. Specifying the ortho- and meta-chloro placement on the toluene ring isn’t just a naming convention—it dictates the reactivity and handling in later stages. Our model reflects long refinement in distillation. Typical lots reach assays above 99 percent by GC, a metric we test for each production run rather than sampling batches indiscriminately. Moisture and acid values stay well below thresholds needed for catalysis or chlorination reactions. Each drum, whether destined for a multinational or a local customer, comes with a profile tied back to the lot it originated from.

    Using Experience to Guide Use and Application

    End users approach us looking for predictability during substitution or coupling reactions where a single unwanted halide or impurity can change yields. We've faced these challenges ourselves when scaling up. With 2,3-dichlorotoluene, a clean baseline ensures that downstream steps—be it further halogenation for specialty dyes or nucleophilic substitution for agrochemical precursors—unfold with less troubleshooting and more productive hours in the plant. Many of our partners work under GMP-certified or closely regulated protocols, and sharing the same batches of starting material over repeated campaigns saves time spent on requalification and validation.

    During implementation, we've watched customers cut reprocessing and disposal when moving from off-spec raw material to our controlled 2,3-dichlorotoluene. Impurities like 2,6-dichlorotoluene or 3,4-dichlorotoluene sometimes hitchhike in poorly purified stocks, especially when origins are unclear. Such minute contaminants, seemingly harmless at first glance, can end up forming unwanted isomers or off-colored byproducts. Through direct feedback loops and open technical exchanges, we've worked with formulators to troubleshoot reaction sequences—an approach that rewards both sides with smoother scale-ups.

    Real-World Demands and Critical Differentiation

    Manufacturing isn’t just about hitting spectral minima or running GC curves. Our experiences in logistics, on-site handing, and even regulatory documentation have shaped 2,3-dichlorotoluene supply toward a product that is more than a line item. Waste disposal protocols and emission limits push users to look not just at price or purity, but lifecycle impact. In Europe and regions with stricter REACH oversight, we incorporate traceability by assigning unique internal tracking, which makes audit trails and compliance checks faster during site reviews. While fewer buyers in southern Asia have requested such paperwork, we’ve kept procedures identical worldwide to avoid costly corrections later.

    A customer once noted unreacted toluene in a competitor’s drum, leading to deviations in solvent balance and inconsistencies in final yield. Our response? Upgrade our stripping process, refine distillation columns, and train staff on in-process sampling—none of this came from theoretical study, but from daily issues flagged by vigilant users. Certain batches undergo extended residence time under vacuum, and if a lot veers off spec, we shut it down instead of blending or reprocessing. We have learned that trust builds over time through action, not just paperwork.

    We don’t pursue one-size-fits-all packaging, either. Some large customers use single bulk shipments requiring precision metering, while research groups order drum lots for laboratory procedures. By staying adaptable and storing product under nitrogen to prevent micro-oxidation, shelf life and stability are maintained even in humid, fluctuating environments. We keep physical samples for several years to cross-reference if breakdown or polymer formation is later reported.

    How 2,3-Dichlorotoluene Stands Apart from Other Chlorinated Toluene Isomers

    Not all dichlorotoluenes show the same behavior during synthesis or storage. The relative positions of the chloro groups on the aromatic ring influence not just the reactivity, but also the physical properties and practical uses. In our work with various clients, the ortho-meta substituted 2,3 form displays distinct solubility and selectivity compared to its 2,4- or 3,4- counterparts. For example, 2,4-dichlorotoluene’s varied electronic distribution makes it preferable in certain dye and pigment protocols, yet 2,3-dichlorotoluene’s arrangement often drives higher yields in nucleophilic aromatic substitution or cross-coupling reactions.

    Unlike suppliers juggling between isomer blends for cost savings, we separate each fraction during the primary chlorination and subsequent purification. This specificity isn’t just about meeting a specification; it allows chemists to avoid side reactions, cut purification steps, and reduce waste. Some research users report that swapping even a minor percentage of the wrong isomer shifts melting points, solubility limits, or color in finished products. Ultimately, understanding and controlling isomer distribution shapes project outcomes—a fact proven in kilo-lab and production environments alike.

    Physical properties distinguish the different dichlorotoluene isomers. Based on past analyses:

    Industry Trends and Addressing Common Concerns

    We keep close watch on trends affecting both our downstream partners and the sector at large. Recent focus on transparency and provenance has pushed many buyers to seek direct-from-manufacturer assurance, not only to weed out mislabeling but to reduce the risk of contamination from mixed-supplier blending. Reports of counterfeit material entering supply chains have only increased vigilance in purchasing and quality teams among existing clients. Our regular third-party audits and transparent labeling go a long way toward keeping scrutiny where it should be: on chemical utility, not questionable sourcing.

    We invest in both bulk and smaller capacity production lines to meet demand surges common during agricultural planning cycles or pharmaceutical innovation pushes. Short-term volatility rarely rattles our established workflows. One of our priorities remains keeping warehouses properly ventilated and monitored, particularly since dichlorotoluenes, though stable, can build to problematic levels if neglected. With rising environmental regulations, especially around halogenated organics, continuous minimization of fugitive emissions and on-site capture of any vented material is more pressing than ever. We choose closed-system tank transfers and real-time monitoring to seal off points where product or vapor might escape.

    Storage questions come up often—whether drums will hold up over humid summers or sub-zero winters. Our coated steel barrels limit both light and air ingress, which matters as small oxidation products can throw off reaction outcomes, particularly where color or electrical properties become important. A few clients in electronics applications taught us this lesson through costly failures in coating processes when using product from unlined drums. Chemical handling details like these inform not just what’s on the COA, but what actually reaches the end user’s reactor.

    Concerns around workplace safety and exposure remain ever-present. We insist on sharing all handling practices directly learned through our facilities, not just generic MSDS advice. In actual use, splash risk and skin absorption remain manageable with standard PPE, but leaks or spills—especially on porous concrete or uncoated surfaces—can require thorough remediation. We continually work with hazardous material consultants to update our protocols and offer this guidance informally to customers, rather than in legalistic footnotes.

    The Future: Supporting Innovation with Responsible Supply

    Our relationship with 2,3-dichlorotoluene is shaped by both tradition and innovation. For decades, basic chlorination chemistry knew few efficiency drivers beyond yield. Today, downstream technologies like greener coupling reagents and low-emission reactors demand more from every input. We’re not turning out vast, undifferentiated volumes but responding in real time as new reaction conditions and stricter quality needs emerge.

    Customers increasingly feed back not only on what’s in the drum but on what is not. Product stewardship has grown inseparable from manufacturing. Newer clients often ask about lifecycle assessments, and we’re preparing more granular reporting on emissions, waste, and recycling routes for every key product, including 2,3-dichlorotoluene. Our own journey toward lower carbon footprint processes runs parallel to helping chemists achieve their own sustainability goals.

    Every lot we produce reflects accumulated knowledge, both ours and our partners’. In today’s marketplace, access to pure 2,3-dichlorotoluene means more than hitting a formula. It’s about ensuring the course of a long project isn’t shaped by unseen variables in the supply chain. Through continuous technical dialogue, regular benchmarking, and an openness about what goes wrong as much as what goes right, our production aims to underpin progress up and down the value chain.

    From a day’s work at the reactor to the quarterly planning meeting, the details make the difference. We think transparent manufacturing, open communication, and shared accountability outweigh the quick savings from cutting corners or outsourcing critical steps. In delivering 2,3-dichlorotoluene, we lay down clear tracks for others to build upon—knowing the future of chemistry rests on a foundation that’s as steady as the science itself.