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2,3-Dichloropropionic Acid

    • Product Name 2,3-Dichloropropionic Acid
    • Alias Dalapon
    • Einecs 221-042-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    633685

    Cas Number 497-21-0
    Molecular Formula C3H4Cl2O2
    Molecular Weight 146.97 g/mol
    Iupac Name 2,3-dichloropropanoic acid
    Appearance White to off-white crystalline solid
    Melting Point 108-112°C
    Boiling Point 209°C
    Density 1.431 g/cm³
    Solubility In Water Moderate
    Odor Pungent
    Pka 2.03
    Flash Point 95°C
    Synonyms Dalapon; 2,3-dichloropropanoic acid
    Ec Number 207-863-3

    As an accredited 2,3-Dichloropropionic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500g amber glass bottle labeled "2,3-Dichloropropionic Acid," with safety symbols, tamper-evident seal, and secure screw cap.
    Shipping 2,3-Dichloropropionic Acid should be shipped in tightly sealed containers, clearly labeled with hazard information. Transport must comply with local, national, and international regulations for hazardous chemicals. The chemical should be kept cool, dry, and away from incompatible substances. Safety Data Sheet (SDS) and emergency contact information must accompany the shipment.
    Storage 2,3-Dichloropropionic Acid should be stored in a cool, dry, well-ventilated area away from heat, sparks, and open flames. Keep container tightly closed and protected from moisture. Store separately from incompatible materials such as strong oxidizers, bases, and reducing agents. Ensure proper labeling, and use corrosion-resistant storage containers. Avoid direct sunlight and sources of ignition to maintain chemical stability.
    Application of 2,3-Dichloropropionic Acid

    Applications of 2,3-Dichloropropionic Acid in Industrial Manufacturing

    2,3-Dichloropropionic acid serves as a specialized intermediate in several tightly regulated downstream sectors, supporting production workflows where controlled reactivity and traceable purity are essential. As a manufacturer with established certifications and audited processes, we supply this material to businesses who require full compliance documentation, consistent batch quality, and technical support for process optimization in application-critical environments.

    1. Synthesis of Selective Herbicide Active Ingredients

    In agrochemical manufacturing, 2,3-dichloropropionic acid functions as a building block for producing specific post-emergence herbicide actives targeting grass species in cereal and sugarcane crops. Formulators integrate this intermediate due to its ability to yield dichlorinated carboxylic acids with precise isomeric purity, essential for biological selectivity. The acid enters synthesis streams where tight control over residual impurities ensures product safety and regulatory acceptance for field applications.

    Industry compliance standards

    • FAO/WHO Specification for Pesticides
    • US EPA Registration Requirements (40 CFR 158)
    • European Chemicals Agency (ECHA) REACH Restrictions for plant protection product intermediates
    • China GB 20813-2006: General rules for pesticide technical material

    Typical usage ratio

    • 10–18% weight in multi-stage synthesis, with exact ratio adjusted by targeted molecule and isomer selectivity.

    Downstream process integration

    • Introduced during the acylation or chloroacetic insertion sequence prior to catalyst-driven condensation reactions; residual acid removed by aqueous extraction after main coupling step.

    Final product types

    • Diclofop-methyl and related AOPP herbicides granules, emulsifiable concentrates, and water-dispersible tablets for agriculture use.

    2. Intermediate for Pharmaceutical Carboxylic Acid Derivatives

    Pharma sector producers source our 2,3-dichloropropionic acid as a key intermediate when manufacturing dichlorinated carboxylate precursors required in synthetic routes of medicinal compounds. QC managers and process chemists rely on documented impurity profiles and on-demand supply tailored to batch synthesis, especially where halogenated side chains influence pharmacodynamic action and regulatory dossier acceptance hinges on traceability and reproducibility.

    Industry compliance standards

    • ICH Q7: GMP for Active Pharmaceutical Ingredients
    • 21 CFR Part 210/211 (US FDA cGMP Regulations)
    • EU GMP Part II: Basic Requirements for Active Substances
    • Japanese Pharmacopoeia (JP)

    Typical usage ratio

    • 0.8–6% weight within specific moiety synthesis, with on-site adjustment based on downstream yield optimization and residual halogen content requirements.

    Downstream process integration

    • Employed in initial alkylation, acylation, or halogenation stages of carboxylic acid precursor synthesis prior to esterification or amidation; carefully monitored for residual chloride elimination in purification steps.

    Final product types

    • Halogen-containing APIs, late-stage intermediates for research compounds, regulatory-submitted pharmaceutical bulk actives.

    3. Precursor in Specialty Polymer Production

    Chemical engineers in the polymer industry utilize 2,3-dichloropropionic acid for introducing functional dichloro side chains during monomer preparation, which in turn are polymerized to yield materials with controlled hydrophilic/lipophilic balance or particular structural properties. The raw material’s purity and well-defined chlorination pattern ensure consistent polymer chain formation, crucial for achieving batch-to-batch reproducibility required for regulated use in coatings and membranes.

    Industry compliance standards

    • ISO 9001 Quality Management for chemical synthesis
    • REACH registration for monomeric substances (ECHA regulations)
    • US TSCA Inventory Notification for new polymer substances
    • EU Regulation (EC) No 1907/2006 (REACH) on polymer intermediates

    Typical usage ratio

    • 2–8% by mole in co-monomer synthesis blends, variably increased according to final physical property targets (hydrophobicity, adhesiveness).

    Downstream process integration

    • Fed into esterification/polycondensation reactors after glycol or diamine initiation and prior to catalyst addition; followed by venting protocols for managing residual chlorinated species before extrusion or casting.

    Final product types

    • Functional acrylic copolymers, polyesters for technical coatings, ion exchange membranes, and specialty adhesives for industrial assembly.

    4. Building Block in Halogenated Fine Chemical Syntheses

    Fine chemical companies integrate 2,3-dichloropropionic acid into multi-step syntheses targeting halogenated small molecules, which serve as performance modifiers, complexing agents, or diagnostic reagents. The acid’s controlled reactivity profile and reagent-grade certification make it suitable for flows requiring clean conversions and facile downstream workup, especially when both supply chain traceability and repeatable outcome are vital for end-user validation.

    Industry compliance standards

    • ISO 14001 Environmental Management for specialty synthesis
    • Responsible Care Program for chemical manufacturers
    • EU CLP Regulation (EC 1272/2008) – Classification, Labelling, Packaging
    • Material traceability documentation per downstream customer requirements

    Typical usage ratio

    • 1.5–5% by overall component mass, precisely calculated based on product specification sheets and validated conversion ratios for each customer project.

    Downstream process integration

    • Charged during controlled halogenation, carboxylation, or ring closure stages in batch or semi-continuous reactors; followed by standard neutralization and phase separation procedures ensuring removal of excess dichloro-acids.

    Final product types

    • Specialty halogenated chain extenders, custom complexing ligands for analytical kits, reagents for laboratory and diagnostic chemical catalogs.
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    Certification & Compliance
    More Introduction

    Understanding 2,3-Dichloropropionic Acid: The Role, Value, and Realities from the Viewpoint of a Chemical Producer

    The Product Journey — Purpose and Purity

    Since we started producing 2,3-dichloropropionic acid, we’ve had a front-row seat for shifts in demand—from its days as a mainstay selective herbicide to its rising pull in the world of custom chemical synthesis. We have seen how the backbone of its utility comes from its dichlorinated structure and manageable carboxylic acid group. These are not abstract features; in production, that practically means better control during synthesis and less fuss around purification steps.

    Within our facilities, the purest batches reach levels above 98%. The sample we keep for reference in our lab gives off a biting, almost vinegary odor, unmistakable once you know it, and this signals consistent manufacture. Our product typically appears as colorless to barely yellowish crystals, with each lot tested to confirm minimal presence of undesirable isomers or residual parent material. By controlling each reactor charge, we keep the 2,3-regioisomer content above 99%, avoiding contamination by 1,3-dichloropropionic acid or undeclared byproducts which can throw off downstream chemistry. This matters—not just for “spec sheet” reasons, but for real-world reasons: a difference in regioisomer means a batch of herbicide or fine chemical behaves unpredictably. Few things lead to lost sleep and ruined shifts for buyers faster than batch-to-batch inconsistency.

    What Sets It Apart — Structural Function and Factory Experience

    Over the years, discussions with supply chain partners and fellow chemists have highlighted what truly sets our 2,3-dichloropropionic acid apart from related acids and dichloro compounds. In the lab, its simple three-carbon backbone with chlorine atoms at positions 2 and 3 makes it less reactive than trichloroacetic acid, but far more targeted than monochloropropionic compounds. The substitution pattern delivers a useful compromise between molecular stability and selective reactivity, which downstream manufacturers count on for making custom herbicides and specialized intermediates. We know from ongoing feedback that some companies tried alternatives like 2,2-dichloropropionic acid or 3-chloropropionic acid only to find the plant uptake profile or reaction selectivity didn’t match up. This is why so many returned to us for this specific acid despite periodic dips in demand.

    Every time we discuss production runs with R&D leads, we look at two things: purity and scale. Smaller labs settling for non-dedicated gear may wind up with trace polychlorinated impurities. Real industrial operations avoid those problems with thorough distillation, dry containment, and ongoing in-process QC. In a mid-sized reactor, our technicians catch issues early using continuous sampling and gas-phase detection. For example, we monitor for runaway exotherms during chlorination and acidification. Our analytical routines always double-check for unwanted hydrolysis or side-chain scission. Over time, we’ve applied these patterns to batches bound for both agricultural and custom-chemical partners, recognizing the timing pressures in these markets.

    Application Areas — From Herbicide to Synthesis

    Long used as a selective herbicide, 2,3-dichloropropionic acid found its mainstay early on in cropping systems that battle perennial grassy weeds. When applied to fields, its action often spares most broadleaf crops, focusing on rhizomatous invaders. The value comes from this species-specific selectivity—something most broad-leaf herbicides can’t offer. But in today’s shifting regulatory and environmental landscape, we see more of our product going to custom synthesis, especially for clients seeking dichlorinated building blocks for new chemical entities. Specialty fine chemical producers reach for this product when they need a C3 chain that delivers both chlorines in specific positions, essential for their route-design in pharmaceutical or agrochemical pipelines.

    We have firsthand experience adapting to evolving usage patterns. Let’s take a recent example from the regulatory front: Some countries started restricting broad use of older dichloro compounds. Customers then asked us to step up our support for technical-grade deliveries, with additional assurances on trace contaminants and waste-handling documentation. We responded by revamping the scrubbing section on our vent lines and expanding our on-site testing area. That adaptation means product batches not only meet traditional herbicide specs, but also R&D-grade requirements for those developing entirely new molecules.

    Production Realities — The Challenge of Consistency

    Manufacturing 2,3-dichloropropionic acid is not a simple affair. Each batch starts with precise weighing of glycerol-derived feedstock and incremental chlorination. Unlike with bulk commodity acids, controlling the exotherm during dichlorination is always a challenge. Failures in the past taught us to invest in better jacketed reactor designs. Temperature swings during exothermic parts of the run can trigger unwanted side reactions, producing trichloro or even chlorinated tar, laying waste to yield and purity alike.

    We run routine gas chromatography with mass spec confirmation on each batch not as a regulatory box-check, but from hard-learned experience. While chlorination chemistry sounds simple at first glance, minor contamination with non-target chlorinated byproducts can render a lot near-useless for critical pathways. Customers using this acid in fine-chemical synthesis or analytical standards have no tolerance for such slippage.

    Given our hands-on role, we understand where costs hide. We buy sodium dichloroacetate, glycerol backbone stocks, and chlorine gas in tankers. Storage and handling alone present some of the biggest challenges—chlorine’s toxicity means careful training and engineering controls. Recent investments in our plant’s emergency shutoff system and operator training have yielded more reliable runs and reduced waste. These practical details may sound mundane, but they drive everything from product safety to operational uptime.

    Why Not "Any" Dichloropropionic Acid?

    Clients sometimes ask, “Why pay more for your 2,3-specification?” We share stories from our own bench—where testing lower-spec commercial dichloropropionic acid led to unpredictable results in both field herbicide trials and pharmachem routes. Lower-grade material can sneak in up to 5% mixed isomers or halogenated byproducts. For industrial formulating, these contaminants can stall a batch or lead to flagged environmental issues on post-emergence crops. In high-purity synthesis, even low levels of misplacement for a chlorine atom on the backbone cause trouble: misfires in coupling reactions, varying pharmacological properties, or new environmental fates altogether.

    Through our batches made at different scales we learned: a product widely regarded as “just a herbicide intermediate” ends up serving high-stakes roles in further synthesis. To ensure every consignment delivers, our process chains trace each raw source to finished, packed acid via real-time digital lot tracking. Recalls, rare as they are, become surgical and precise. Our customers expect transparency and proven traceability—not to tick a “good company” box, but because a fouled batch can mean a loss in the hundreds of thousands and months lost in regulatory filings.

    Differences Beyond the Surface

    2,3-dichloropropionic acid’s distinction doesn’t end at just chemical positioning. Compared with 2,2-dichloropropionic acid or monochlorinated alternatives, its environmental breakdown follows a different route. We engage in ongoing studies, collecting real-site soil data and working alongside agronomists to assess any risk of residue carryover. In agricultural use, farmers and regulatory agencies scrutinize not only efficacy but also persistence, leachability, and animal health. This pushes us to keep impurity levels low and to provide real figures from our decomposition and dissipation studies—an approach not every supplier pursues.

    Our production lines are designed for changeover and dedicated flushes. That way, a batch for a new pharma client needing crystallographic-grade acid never risks cross-contamination from the previous run destined for an herbicide blend. By handling these transitions at scale, we keep lead times steady even through busy seasons and surge requests.

    Case Files — What’s Changing and Driving Demand

    Change drives our part of the business, and 2,3-dichloropropionic acid proves it every year. Once, all demand pointed to regional herbicide formulation. Now, as restrictions and consumer scrutiny increase, research-grade demand is on the rise. Recent shifts include new contract orders for intermediate production rather than blending. Clients now care less about bulk pricing and more about validated purity, analytical support, and clear batch histories. An order from a pharma startup is not the same as one from an agricultural cooperative.

    This shift prompted us to put more energy into method validation, especially where downstream clients use our material as an anchor in custom syntheses. To answer those needs, our plant now integrates frequent third-party audits. Random, unannounced tests catalog lots from final packaging back to initial raw input days or weeks prior. Any deviation triggers a root-cause investigation—no exceptions.

    Some customers need detailed impurity profiles down to sub-ppm levels, requiring stronger quality programs and better-trained lab techs. To meet demand in Europe and North America, we made a deliberate investment in compliant storage, enhanced analytical machinery, and local language technical dossiers. These clients want more than “meets specification”—they need assurance validated by data, by anecdotal plant experience, and, often, on-site factory visits.

    Supporting Facts & Industry Realities

    We have cultivated industry trust by openly sharing experiences, both positive and tough. For instance, a few years ago, a production line suffered a contaminant run due to a gasket failure undetected in maintenance rounds. Rather than dodge the incident, we issued detailed analysis to our customers, revoked the affected lots, and implemented new gasket replacement protocols. Since then, batch-to-batch impurity rates dropped below the industry’s usual 0.5% cap, routinely verified not only by our labs but also by selected customer audits.

    Few suppliers regularly update their batch-release records as clearly, but we see more value in candid relationships. We believe this helps everyone avoid sudden supply shocks. After nearly two decades in business, we know that trust and transparency matter alongside purity and price. From our seat as a producer, every innovation or process control feeds directly into what the customer receives—and in a field like specialty organics, that edge often becomes the deciding factor between a reliable supply and a risky gamble.

    Potential Challenges and How We Navigate Them

    Operating any chemical plant requires more than technical know-how; it means responsibility to community, workforce, and the environment. Production of 2,3-dichloropropionic acid carries waste management concerns, especially regarding residual chlorinated water. We took member input from regional environmental programs seriously, investing in a closed-loop water treatment system. Chlorinated waste streams pass through carbon filtration and monitored biological digestion before final discharge. Quarterly samples go out for external review—avoiding toxic release build-up and demonstrating responsible operation to regulators.

    With supply chain jitters rising worldwide, raw material fluctuations hit specialty producers hard. To buffer clients against these spikes, we work with a diversified supplier network, regularly reviewing contracts and stocks. Reliable supply hinges on anticipation—not only for our partners, but for our teams. During a recent chlorine price spike, we drew on stored feedstock and kept order fulfillment uninterrupted for several key clients. That upfront planning makes a difference when market turbulence threatens to disrupt downstream business.

    Our experience shows it pays to be nimble and to listen. Feedback loops from end users—the ones working fields or running analytical reactors—push us to adapt. If batches trend out of spec or recurring packaging issues show up, rapid internal adjustments follow. This isn’t just “customer focus”—it’s built on hundreds of calls and field visits. By shifting from standard-issue barrels to tailored packaging for one pharmaceutical buyer, we enabled safer, easier handling—cutting both loss and workplace incidents.

    Final Thoughts — Real-world Impact and the Path Ahead

    Producing 2,3-dichloropropionic acid offers a window into how specialty chemicals shape larger industrial and agricultural processes. It’s a product rooted in decades-old chemistry, yet always evolving. End-users count on us for more than a commodity. They need assurance that each lot matches what’s been promised—no excuses, no surprises. That’s a value built not only on technical know-how but on willingness to share experience, learn from feedback, adapt to regulation, and own up to mistakes. Every drum, every sample, every delivery is a statement of our commitment to getting it right—so customers can do the same further down the line.

    Looking ahead, we focus on continuous improvement—whether that means better impurity control, safer plant conditions, or more responsive support. The challenges posed by evolving regulations, changing markets, and better-informed buyers shape how we operate. They don’t lead to shortcuts or compromise; they prompt us to sharpen our processes and deepen connections with the people who rely on our work. From our perspective, that’s how every specialty chemical, especially 2,3-dichloropropionic acid, ought to be made.