Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2,3-Dichlorophenyl Isothiocyanate

    • Product Name 2,3-Dichlorophenyl Isothiocyanate
    • Alias 2,3-DCPI
    • Einecs 221-009-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    449478

    Chemical Name 2,3-Dichlorophenyl Isothiocyanate
    Cas Number 13357-24-1
    Molecular Formula C7H3Cl2NS
    Molecular Weight 204.08 g/mol
    Appearance Light yellow to brown liquid
    Boiling Point 108-110°C at 10 mmHg
    Density 1.44 g/cm3
    Purity Typically ≥97%
    Solubility Soluble in organic solvents (e.g., ethanol, acetone)
    Flash Point 125°C
    Smiles C1=CC(=C(C(=C1)Cl)Cl)N=C=S

    As an accredited 2,3-Dichlorophenyl Isothiocyanate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle labeled "2,3-Dichlorophenyl Isothiocyanate, 25g" with hazard warnings, tightly sealed, shipped in protective secondary packaging.
    Shipping 2,3-Dichlorophenyl Isothiocyanate should be shipped in tightly sealed containers, clearly labeled, and protected from moisture and direct sunlight. Handle as a hazardous chemical, in compliance with DOT/IATA regulations. Use secondary containment, appropriate hazard labels, and ensure the shipment meets all relevant safety and documentation requirements for toxic organic compounds.
    Storage Store 2,3-Dichlorophenyl Isothiocyanate in a tightly sealed container in a cool, dry, and well-ventilated area, away from direct sunlight, moisture, and incompatible substances such as strong oxidizers and acids. Avoid exposure to heat sources. Use appropriate chemical-resistant storage cabinets, and ensure proper labeling. Handle under a fume hood, and follow all applicable safety protocols and regulations.
    Application of 2,3-Dichlorophenyl Isothiocyanate

    Applications of 2,3-Dichlorophenyl Isothiocyanate in Industrial Manufacturing

    2,3-Dichlorophenyl Isothiocyanate serves as a vital building block in several high-value chemical synthesis processes. As a direct manufacturer, we supply this intermediate to industries that require stringent quality, formulation precision, and traceability from raw material intake to finished product release. Below are key downstream applications, each selected based on established industrial practices and sector-specific compliance protocols.

    1. Crop Protection Active Ingredient Synthesis

    Large-scale agrochemical producers utilize 2,3-dichlorophenyl isothiocyanate for synthesis of specific thiourea and urea-based herbicides and fungicides. This compound undergoes nucleophilic addition reactions, typically with amine co-reagents, as part of multi-step pathways to create highly targeted bioactive molecules. We maintain batch consistency to meet traceability and regulatory registration demands in regulated agro markets.

    Industry compliance standards

    • Global GAP standards for active ingredient purity
    • EU REACH registration and dossier data (EC 219-121-7)
    • US EPA pesticide registration requirements
    • China Agricultural Industry Standard (GB/T 1606-2017 for intermediates)

    Typical usage ratio

    • Ranges from 0.15–0.30 molar ratio in coupling step, adjusted by target molecule structure
    • Mol-to-mol basis with 3–5% material excess for full conversion

    Downstream process integration

    • Charges at the controlled addition phase of active ingredient core synthesis
    • Integrated under inert atmosphere in batch reactors to minimize hydrolysis risk
    • Follows by quenching, extraction, and downstream formulation into technical concentrates

    Final product types

    • Thiourea-based herbicides (e.g., specific aryl-substituted products)
    • Systemic fungicides for seed and soil treatment
    • Registered crop protection intermediates for further synthesis

    2. Pharmaceutical Intermediate for Sulfonylurea Compounds

    Producers of bulk pharmaceutical intermediates use 2,3-dichlorophenyl isothiocyanate for the synthesis of certain aryl isothiocyanate cores, further converted into sulfonylurea structures. These intermediates enter global API supply chains, especially for anti-diabetic actives and research-grade compounds. Stringent GMP traceability and impurity control ensure acceptance by regulated end users.

    Industry compliance standards

    • ICH Q7A GMP guidance for API/intermediate manufacturing
    • USP/NF and Ph. Eur. monographs for process-related impurities
    • Chinese Pharmacopoeia requirements for synthetic intermediates

    Typical usage ratio

    • 0.20–0.28 molar equivalents, adjusted for coupling efficiency and minimized by-process impurities
    • Batch adjustment required for each registered synthesis route

    Downstream process integration

    • Dosed at condensation phase with aryl amines in dry polar solvents
    • Incorporates into closed GMP cisterns, followed by stepwise chemical transformation
    • Strict in-process QC sampling at reaction completion before downstream purification

    Final product types

    • Sulfonylurea intermediates for antidiabetic pharmaceutical API synthesis
    • Research-scale reference standards
    • Advanced intermediates supplied to CDMO/CMO clients

    3. Specialty Dye Intermediate Production

    Manufacturers producing specialty dyes employ this material for producing dichloroaniline derivatives via nucleophilic reactions with amines. These intermediates contribute to multi-stage dye synthesis used in high-performance textile, inkjet, and industrial colorant formulations. Carefully controlled reaction conditions help minimize by-product formation and ensure high-purity chromophores for downstream blending.

    Industry compliance standards

    • Oeko-Tex Standard 100 for hazardous compound restrictions
    • EN 71-3 (Toy Safety, for colorant traces in children’s textiles)
    • Registration with Korean Toxic Chemicals Control Act (TCCA)

    Typical usage ratio

    • Typical 0.10–0.18 molar equivalents per target dye molecule
    • Levels adjusted to ensure full reaction and minimize extraction waste

    Downstream process integration

    • Dosed during aromatic amination steps
    • Introduced before oxidizing and final coupling stages
    • Multiple-stage purification to achieve high color fastness and low residue

    Final product types

    • Disperse dyes for polyester fabrics
    • Reactive dyes for cellulosic fibers
    • Industrial inks for specialty coatings and digital printing

    4. Polymer Crosslinking Agent Synthesis

    Chemical manufacturers employ 2,3-dichlorophenyl isothiocyanate for crafting crosslinking agents incorporated in specialty elastomer and engineering resin production. This application utilizes its thio-functional reactivity to link polymeric chains under controlled curing conditions. Strict process controls govern the introduction of the agent to achieve targeted mechanical resilience and heat resistance in final resins.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems for specialty chemical manufacture
    • RoHS Directive compliance (for electronic and automotive plastics)
    • UL 94 flammability testing for polymer additives

    Typical usage ratio

    • Usage at 0.5–2.0% by weight, dependent on molecular weight of target polymer matrix
    • Formulation teams adjust loadings for required crosslink density

    Downstream process integration

    • Blended during masterbatch compounding operations
    • Added to reaction vessels prior to heat-initiated or chemical curing
    • Integrated with functional fillers and colorants as required

    Final product types

    • Engineering resins with enhanced heat and solvent resistance
    • Elastomeric gaskets and O-rings for automotive and electronics
    • Specialty rubber compounds for cable insulation

    5. Industrial Biocide Intermediate Manufacturing

    Specialty chemical companies synthesize industrial biocides using this raw material for isothiocyanate-based derivatives that impart antimicrobial and antifungal properties. Manufacturers use it in multi-step lines for cooling tower, oilfield, and paint preservatives. Carefully controlled reaction environments and batch traceability ensure compliance with end-use microbe resistance specifications and regulatory labeling.

    Industry compliance standards

    • US EPA FIFRA for industrial biocides registration
    • EU Biocidal Products Regulation (BPR, Regulation (EU) 528/2012)
    • ISO 11930 (Preservative efficacy in industrial formulations)

    Typical usage ratio

    • Applied at 0.12–0.22 molar equivalents, depending on final biocide formulation requirements
    • Adjusted based on microbial spectrum targeted in product development

    Downstream process integration

    • Introduced during synthesis of active biocidal agents
    • Followed by neutralization and controlled crystallization or isolation
    • QC checks at intermediate isolation for microbial activity and purity

    Final product types

    • Isothiocyanate-based preservatives for polymer emulsions
    • Bactericides for industrial water treatment
    • Mildewcides for architectural coatings
    Free Quote

    Competitive 2,3-Dichlorophenyl Isothiocyanate prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2,3-Dichlorophenyl Isothiocyanate: A Key Ingredient Backed by Hands-On Manufacture

    Direct from Manufacturers, Not Middlemen

    Working in chemical manufacturing brings a unique understanding of the materials we produce. Years in the plant allow close attention to each batch, so our 2,3-Dichlorophenyl Isothiocyanate carries more than a name on a drum. Every kilo that leaves our site follows strict quality routines established through decades in this line of business. The goal has always been to provide a consistent high-purity isothiocyanate, and our production teams know that users downstream depend on every specification we guarantee. On our shop floor, we use batch synthesis and real process knowledge to keep those standards, not just checking boxes on a sheet but making sure each lot delivers what chemists expect.

    We know our customers well: research labs developing new pharmaceutical intermediates, agrochemical formulators, and specialty chemical firms with tight production schedules. Many worked with generic isothiocyanates before, sometimes burning valuable time on extra purification steps just to avoid impurities skewing sensitive reactions. They started asking for something better — 2,3-Dichlorophenyl Isothiocyanate with high lot-to-lot reliability, ready for direct application without headaches later on.

    Model, Specifications, and Experience-Guided Production

    Manufacturing this product demands practical chemistry know-how. At our plant, we synthesize 2,3-Dichlorophenyl Isothiocyanate in reactors set up for full control over reaction conditions. Monitoring temperature, pressure, and time is not just a compliance task here — it's the guarantee that the product meets consistent chemical identity with every run. We focus on purity, keeping chlorinated contaminants and byproducts low, because end users report that even small variations cause trouble down the line. Our typical product has a purity level above 98%, often measured batchwise using HPLC and NMR on-site. Moisture content gets monitored right after synthesis since exposure to ambient air can affect storage stability.

    We don't stop at published data. Operators run routine checks and supervisors encourage any team member to flag issues before packing. Years of hands-on work taught us that seemingly minor mistakes can escalate if ignored — something no data sheet ever warns about. Filling and sealing take place in a closed system under nitrogen. This keeps the product free of excess moisture and stops airborne contamination, which would otherwise affect sensitive syntheses in pharmaceuticals or agricultural chemistry.

    Standard packaging follows sizes developed together with users: amber glass bottles for small-scale lab use, secure steel drums and lined HDPE containers for industrial volumes. Each batch is traceable, down to every test and material log. Fast, accurate tracing stops problems and keeps customer lines running, especially for long-term contracts in regulated markets.

    Use in the Real World

    Chemists and process engineers reach for 2,3-Dichlorophenyl Isothiocyanate when reliability counts. Our product's main application areas include the synthesis of biologically active compounds, especially those where the 2,3-dichloro substituents promote targeted reactivity. Some pharmaceutical projects use it to introduce isothiocyanate moieties into candidate molecules. Its structure makes it valuable in the construction of complex heterocycles and sulfur-containing intermediates. In crop protection, it provides intermediate steps for new pesticide entities due to its chlorinated aromatic ring and reactive isothiocyanate group. Custom and contract manufacturers often tell us the difference: dealing directly with plant teams means they can request tailored specs or ask technical questions that generic suppliers can’t answer.

    We know isothiocyanates in general have a reputation as challenging reagents. Their reactivity, while useful, also means safe handling and predictable supply matter as much as chemical data on a website. Our experience running this product in-house lets us offer frank advice on scale-up, storage, and real-life hazards rarely covered in textbooks but well-known to plant operators who work with these chemicals every day.

    Other use cases come up in polymer development, specialty dyes, and certain flavor and fragrance syntheses — all reliant on the reliable supply of a clean, well-defined isothiocyanate group. Our chemical’s subtle differences from more common isothiocyanates mean customers must watch their process chemistry closely. We keep technical staff available to talk shop and address unique requirements, because experience taught us how fine details make a world of difference.

    How This Differs from the Usual Isothiocyanates

    Working day in and out with 2,3-Dichlorophenyl Isothiocyanate, we've learned its quirks versus more routine alternatives. A lot of labs begin with phenyl isothiocyanate or para-chlorinated variants, but too often, results aren’t as precise or reactions go slower, especially when stepwise synthesis requires selective reactivity. Our 2,3-dichloro version offers distinct electron-withdrawing effects from both ortho and meta positions, enhancing its utility in some coupling and cyclization contexts where mono-substituted or unsubstituted isothiocyanates fall short.

    Customers share how even small process changes make certain generic isothiocyanates unusable for sensitive reactions. Our material, by contrast, provides reproducible performance and robust reactivity thanks to the two chlorine substituents, which don’t show up together in many commercial alternatives. Bulk suppliers without direct manufacturing control often struggle to match our post-synthesis purification and packaging routines, leading to higher residual solvent, unexpected impurities, or erratic product behavior during storage and application.

    Some isothiocyanates boast broader market availability or cheaper prices, but production methods remain inconsistent across the industry. Since we control the full manufacturing route from raw aromatic ring selection to final container, our batches deliver much tighter purity profiles, drastically reducing troubleshooting for specialist applications. This means less rejection in QC departments, fewer failed syntheses in high-value active pharmaceutical ingredient (API) campaigns, and less risk management for buyers who bet their timelines and budgets on trustworthy input material.

    Our Commitment: Hands-on Expertise vs. Anonymous Sourcing

    Manufacturing isn’t just about drills and vessels. Each member of our team takes direct responsibility for product integrity. Family histories built around chemical craft remind us that trust comes from exacting standards, not clever marketing. Engineers run final sign-offs and warehouse teams track the last detail, from packaging lot numbers to test records. We share lessons learned — like never accepting small changes in raw material supply, tight handling of waste, or the critical role of preventive maintenance on process equipment. These facts get baked into our workflows, so the 2,3-Dichlorophenyl Isothiocyanate you receive matches the material standards we've built our business on.

    The market always pulls in new traders, re-packers, and fast-turn operators. Some buyers learn the hard way that supposed “manufacturer” listings often mask third-party repacks with questionable provenance. Having our own reactors, analytical equipment, and a close-knit staff lets us offer stable supply and responsive advice through every stage of the order cycle — from development batches to scale-up and regulatory audits. Direct-manufacture experience also helps us minimize contaminants that would easily slip through in a less-controlled setting.

    Practical Issues, Practical Solutions

    Real-world chemical production never runs in isolation. Cost pressures, logistics, environmental laws, and shifting customer needs all shape what we do on the plant floor. The 2,3-Dichlorophenyl Isothiocyanate we produce reflects bottom-line decisions, but these don’t override the basics of chemical craftsmanship. If regulations shift, or a customer’s use changes, our teams have direct experience troubleshooting new shelf life rules, revalidating product when feedstocks change, or certifying new packaging formats for hazardous materials. We built partnerships with global couriers and local freight carriers who know the ins and outs of regulated shipments — some drivers even recognize our containers at the dock.

    An example from not long ago: during a feedstock interruption, some suppliers scrambled to keep up with contract shipments by substituting intermediates without full revalidation. Our approach — halting batches temporarily, verifying new raw material lots against tight in-house standards, and running pilot tests — won back trust among API manufacturers down the line, who had felt the domino effect in their supply chains. Cutting corners isn’t worth a quick sale when it destabilizes years of work and risks customer loyalty. Direct production oversight ensured our clients didn’t see quality slip.

    Waste disposal remains another challenge. Chlorinated byproducts require careful, documented handling and legal disposal in modern facilities. We run incineration and effluent control in-house, maintaining compliance logs and welcoming unannounced environmental checks. Production management treats safety culture and regulatory traceability as daily work, not as slogans. This keeps our neighbors and regulators satisfied and gives reassurance to customers who face increasing documentation requests from their own compliance teams.

    Support, Questions, and Next Steps

    Even for experienced technical buyers, subtle differences in 2,3-Dichlorophenyl Isothiocyanate grades matter. Our plant laboratory fields requests for extra data, supply certificates, stability studies, and root-cause investigations. Sometimes customers call with questions about physical characteristics — such as color, odor, or melting point variations — or request advice on transfer and storage methods that minimize operator risk. Our in-house chemists give answers based on practical outcomes, not theoretical textbook values. Experience tells us that transparent, candid conversations help both sides avoid costly mistakes.

    Requests for unusual volumes or emergency shipping come in regularly. Decades of managing international exports taught us how different countries regulate chlorinated isothiocyanates, so we modify everything from document packs to container labels as standards shift. Issues like port compliance delays or freight embargoes never fully disappear, but our logistics teams track legal updates and work in advance to keep customers supplied, whether for small research quantities or industrial-scale contracts.

    Sometimes, clients need a custom twist on the base chemistry — tighter impurity control, lower residual solvents, or specific isomer content as process requirements become more exacting. Our production staff run development batches, document new methods, and provide samples before approval. Working inside a manufacturing plant, our teams respond in days, not months, to special project demands.

    Field-Tested Value for Industry and Research

    The best test of a high-value chemical lies in its real-world impact on user processes. Over the years, feedback from med-chem research leaders, agricultural R&D labs, and bulk process engineers guided our process improvements. Our 2,3-Dichlorophenyl Isothiocyanate now features lower trace metals and minimal unwanted aromatics, thanks to targeted tweaks in raw material supply and purification technique. Large-scale users appreciate not having to overfilter or recrystallize substancial quantities just to meet their own standards; time saved in purification translates to higher process throughput and less chemical waste.

    Unlike off-the-shelf intermediates from third-party suppliers, our product avoids supply bottlenecks and shifting specs. Research clients recount projects derailed when unstable supply forced sudden reformulations or revalidation, costing months and racking up budget overruns. Providing assurance of compound quality lets them focus on innovation instead of troubleshooting inputs. For us, building long-term relationships with repeat buyers proves more rewarding than chasing one-off sales.

    Regulated industries, especially pharma, have strict requirements on change notification. Our in-house team knows the importance of communicating every recipe or plant maintenance adjustment, offering validation packs and documentation to keep customer records up-to-date. This has kept our 2,3-Dichlorophenyl Isothiocyanate listed as an approved intermediate on many site master files without confusion during audits or re-inspection.

    Future-Ready: Keeping Pace with Evolving Standards

    Markets change and regulatory bar moves each year. To keep pace, our chemists track advances in analytical methods and test new purification tools — such as -degree NMR, mass spectrometry, and advanced chromatography — ensuring batches stay within even tighter future tolerances. Environmental reforms in disposal protocols and emissions controls push us to upgrade air scrubbing units, re-validate all waste channels, and work with environmental authorities proactively rather than retroactively. These challenges shape the way we make, test, and ship 2,3-Dichlorophenyl Isothiocyanate, so new clients can count on uninterrupted supply and on-spec chemical intermediates.

    Green chemistry trends add another layer of complexity. We examine ways to minimize solvent usage, recycle reactor wash streams, and re-use reaction byproducts as secondary inputs. These aren’t just regulatory demands — they’re practical decisions that reduce generation costs and keep us ahead in an industry under tightening global scrutiny. Collaboration with research institutes and industrial partners lets us road-test sustainable technologies before they become mainstream requirements.

    Direct Dialogue: Manufacturer to End User

    Through years of hands-on manufacturing, our team observed that open, honest exchange with buyers, engineers, and researchers generates better results than relying on layers of intermediaries. We openly discuss batch analysis, past production challenges, and the specific strengths and weaknesses 2,3-Dichlorophenyl Isothiocyanate holds for any proposed process. Our operators recall details about trends in failed syntheses and flag recurring pain points for users. This level of cooperative transparency accelerates troubleshooting and process development, helping teams hit ambitious project targets with fewer delays.

    Repeat customers know they’re not just buying a chemical — they’re getting access to expertise forged in real production environments, where one misstep can mean a ruined run or shipment delay. This partnership approach stands apart from bulk procurement through anonymous channels. Every drum shipped reflects not only the hard metrics — purity, batch traceability, and regulatory compliance — but also our plant culture of accountability and pride in quality work. For buyers frustrated with unreliable supply or inconsistent spec from third-party vendors, our direct production means a smoother workflow with fewer unpleasant surprises.

    The practical, real-world value of 2,3-Dichlorophenyl Isothiocyanate — in yield, process consistency, compliance, and technical support — flows directly from the way we manufacture, package, and ship each lot. Our confidence is built on our team’s diligence and decades of seeing what can go right, and what can go wrong, in chemical production. Purchasing from a genuine manufacturer isn’t just about source identification on a shipping manifest. It’s about building confidence that every shipment will help, not hinder, your next critical batch or discovery.