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2,3-Dichlorobutane

    • Product Name 2,3-Dichlorobutane
    • Alias 2,3-Dichlorobutan
    • Einecs 211-260-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    128339

    Iupac Name 2,3-Dichlorobutane
    Molecular Formula C4H8Cl2
    Molar Mass 127.02 g/mol
    Appearance Colorless liquid
    Boiling Point 108-109 °C
    Melting Point -54 °C
    Density 1.17 g/cm³
    Cas Number 3197-13-5
    Refractive Index 1.434
    Solubility In Water Insoluble
    Flash Point 25 °C
    Pubchem Cid 13599

    As an accredited 2,3-Dichlorobutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle labeled "2,3-Dichlorobutane," with hazard symbols, secure screw cap, and safety instructions included.
    Shipping 2,3-Dichlorobutane should be shipped in tightly sealed, clearly labeled containers, compliant with local and international regulations. Store and transport it in a cool, well-ventilated area, away from heat, sparks, and incompatible substances. Use appropriate hazard labels, and ensure handling by trained personnel with proper protective equipment. Handle as a hazardous material.
    Storage 2,3-Dichlorobutane should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat sources, ignition sources, and incompatible materials such as strong oxidizers. Keep it out of direct sunlight and separate from food and drink. Properly label the storage area and container, and ensure access is restricted to trained personnel only.
    Application of 2,3-Dichlorobutane

    Applications of 2,3-Dichlorobutane in Industrial Manufacturing

    2,3-Dichlorobutane functions as a key intermediate across several chemical manufacturing sectors due to its well-defined chlorinated structure and reliable reactivity profile. Below, we detail principal downstream applications based on actual market demand, specifying industry compliance, dosage levels, process steps, and the nature of resulting finished products.

    1. Pharmaceutical Intermediate Synthesis

    Manufacturers in the pharmaceutical sector utilize 2,3-dichlorobutane as a selective building block for synthesizing active pharmaceutical ingredients (APIs), including chlorinated alkanes, anti-infective precursors, and custom chiral intermediates. It interfaces into substitution and coupling reactions, offering reliable yields due to defined purity standards. Required documentation and quality certification align these use cases with regulated production pipelines, supporting GMP-compliant output in bulk API projects targeted at both generic and branded drug supply chains.

    Industry compliance standards

    • ICH Q7 GMP for active pharmaceutical ingredients
    • USP and Ph. Eur. monograph compliance for related substance controls
    • 21 CFR Part 210/211 (U.S. FDA current Good Manufacturing Practices)
    • EU REACH (EC 1907/2006) registration for pharmaceutical chemical substances

    Typical usage ratio

    • Applied at 0.2–2 molar equivalents depending on the halogenation or alkylation step
    • Stoichiometric quantity adjusts based on the specific API molecular complexity and yield optimization targets

    Downstream process integration

    • Intermediate introduction follows initial alkane functionalization (e.g., pre-halogenation or reduction)
    • Raw material feeds directly into nucleophilic substitution or cross-coupling reactions
    • Purity and residual solvents are assessed post-integration before downstream isolation or crystallization
    • Material removed at intermediates purification or further functionalization step

    Final product types

    • Antimicrobial and antiviral APIs
    • Chlorinated substituted API intermediates
    • Bespoke small-molecule drug candidates
    • Batch or continuous flow intermediates for pharmaceutical outsourcing and CDMO contracts

    2. Agrochemical Synthesis (Herbicides and Pesticides)

    This compound plays a role in controlled halogenation reactions for the synthesis of specific agrochemical actives. Its consistent quality and high reaction specificity underpin the manufacture of complex chlorinated herbicide and pesticide molecules, often demanded by both multinational and local formulators. Compliance with crop protection regulations necessitates rigorous process documentation from intermediate handling to final product dispatch, and dictates traceability according to local import/export standards.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems for chemical synthesis plant operations
    • FAO/WHO specifications for technical pesticide material
    • Regulation (EC) No 1107/2009 (EU plant protection product laws)
    • US EPA Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) for active ingredient registration

    Typical usage ratio

    • Ranges from 0.05–0.75 mass fraction in active ingredient synthesis protocols
    • Ratios depend on target crop spectrum and downstream co-formulant selection in the herbicide or pesticide pipeline

    Downstream process integration

    • Raw material enters post-chlorination phase, facilitating chain-elongation, alkylation, or further chlorination steps
    • Managed under closed system charging with in-line QC for impurity cutoffs (dichlorinated byproducts)
    • Intermediates formed transfer to final product finishing lines under monitored temperature and agitation control
    • Compliant storage and handling protocols maintained throughout for residue analysis

    Final product types

    • Technical active pesticide concentrates
    • Selectivity-tuned herbicide formulations
    • Bulk intermediates for custom agrochemical manufacturing
    • Emulsifiable non-systemic pesticides for regional markets

    3. Polymer and Specialty Chemical Additive Manufacturing

    In specialty polymer plants, 2,3-dichlorobutane serves as a chain-modifying agent for tailored halogenated polymer resins and as a precursor in chemically resistant plastics. It is also integrated as a controlled chain stopper or crosslinking agent in the synthesis of advanced engineering thermoplastics. Quality-certified input ensures that the final polymer matrix meets performance requirements for downstream automotive, construction, or electronics sectors.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management Standards for polymer plants
    • UL 94 (Flammability of plastic materials for parts in devices and appliances)
    • RoHS Directive (2011/65/EU) for electronic-use plastics
    • ASTM D256 and D638 for polymer mechanical properties

    Typical usage ratio

    • Implemented at 0.1–2 weight percent in halogenated polymer modifications
    • Exact level adjusted according to crosslink density and target flame retardancy or chemical resistance grade

    Downstream process integration

    • Fed into initial polymerization reactors with in-process viscosity and molecular weight controls
    • Introduced during final resin stabilization phase for tailored end-use performance
    • Incorporated before thermal extrusion, compounding, or pelletization steps
    • Regular raw material assays run prior to batch acceptance and post-run for residue checks

    Final product types

    • Halogenated polyethylene and other specialty resins
    • Flame-retardant composite materials
    • Chemically resistant sheets, rods, and films for industrial installations
    • Electronic component encapsulants and housings

    4. Fine Chemical Custom Synthesis

    Contract synthesis and fine chemical manufacturers use 2,3-dichlorobutane in multi-step organic syntheses requiring specific dichloroaliphatic intermediates. Its introduction as a controlled reactant ensures batch reproducibility, meeting strict documentation needs for custom project dossiers. Laboratories and production plants routinely validate raw material identity and purity, integrating this compound into sequence-controlled functionalization, with analytical verification at each stage.

    Industry compliance standards

    • ISO 9001:2015 for custom chemical supply
    • ISO 17025 laboratory accreditation for QC release
    • Material Safety Data Sheet (MSDS) provision per GHS and local regulatory requirements
    • Custom client and agency quality agreement standards

    Typical usage ratio

    • Applied within 0.05–1.5 molar equivalents relative to the target backbone
    • Adjustment based on project yield expectations and side product minimization strategies

    Downstream process integration

    • Compound added after in-situ base generation or Grignard reagent preparation
    • Charging performed under reduced light and oxygen for sensitive transformations
    • Post-use, product mixtures undergo chromatography or distillation for intermediate isolation
    • Residual analysis and SPC (statistical process control) maintained across campaign

    Final product types

    • Advanced dichloro-functionalized fine chemicals
    • Custom synthesis blocks for bioactive molecule construction
    • Research laboratory reference standards
    • Specialty intermediates for global contract manufacturing partners
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    Certification & Compliance
    More Introduction

    Understanding 2,3-Dichlorobutane: Reliability from Chemical Manufacturing Expertise

    Introducing 2,3-Dichlorobutane: From Production Floor to Precise Application

    Every batch of 2,3-Dichlorobutane we ship represents years of hands-on chemical synthesis and careful quality control. In our facility, our team handles the full manufacturing process, focusing on consistency in purity, controlled contaminant levels, and reliable physical properties batch after batch. Whether it’s the crystal clarity in the sample vials coming off the line or the robust, sealed drums for bulk delivery, our approach never cuts corners—because we’ve learned through direct experience that quality starts on the reactor floor, not just in a lab spec sheet.

    As genuine producers, we’ve come to know 2,3-Dichlorobutane by more than just its CAS or molecular structure. This compound stands out for its specific di-chlorination pattern, with chlorines attached at the 2 and 3 positions of the butane backbone. This structural layout gives it different reactivity patterns compared to 1,2- or 1,4-substituted isomers, and the difference emerges clearly once you apply it in real syntheses. For researchers or process chemists trying to build more complex chemicals, these natural properties either open up selective reaction pathways or help close off routes where precision matters.

    Model and Specifications that Matter in the Field

    Rather than getting bogged down in abstract purity percentages, our manufacturing team tracks every variable impacting the final product: control of starting materials, clean handling during dichlorination reactions, and real-world analytics like gas chromatography profiles. Our standard model arrives as a colorless liquid, typically shipped in steel or lined PE drums. Each lot is accompanied by COA records with consistent GC area purity above 98%. We do more than run basic tests; we aim for tight control over trace residuals and often work with clients to match special low-chloride or ultra-low halogen specs, depending on project needs.

    Having a direct relationship with our researchers and technical staff gives us a front-line view. Sometimes, a request comes in with an unusually demanding threshold for residual solvents or chlorinated byproducts. Other times, a partner needs a custom fraction cut, tuned for their process downstream. We have built out both our manufacturing plant and our analytical procedures to handle these needs efficiently. This agile process isn’t just paperwork—it’s an investment in our own in-house skills and equipment, made over years of ongoing improvement.

    Why 2,3-Dichlorobutane Shines in Synthesis and Industry

    Over the years, 2,3-Dichlorobutane has developed a quiet but crucial following in the fine chemicals and pharma-building-block world. We’ve seen it serve as an intermediate for crafting specialty alcohols, ketones, and detailed molecules that require reliable halogenation. The placement of both chloride atoms on adjacent carbons creates unique reaction handles—allowing for targeted substitution, elimination, or coupling steps that just aren’t feasible with other chlorinated butanes. Clients in polymer manufacturing, agricultural chemistry, and pharmaceutical development rely on these differences to shape the backbone of more complex compounds.

    In one project, a customer pushed our technical department to deliver 2,3-Dichlorobutane with a super-low water content profile. The end product depended on a water-sensitive reaction cascade, and even a small residual introduced downstream headaches. Our team responded by working with them side-by-side—adapting the drying steps and scaling up Karl Fischer titrations for every lot. These collaborations are where actual manufacturing experience comes into play: decisions to tweak process flows, shift drying conditions, or implement new purge gases don’t happen from an armchair—they come from direct responsibility for both process and outcome.

    Differentiating 2,3-Dichlorobutane: Beyond Standard Isomers and Grades

    The butane family has several chlorinated cousins—each with strengths and specific end-uses. We routinely field questions about the practical differences between 2,3-Dichlorobutane and its close relatives, like 1,2-Dichlorobutane or 1,4-Dichlorobutane. In our plant, separating and purifying the specific 2,3- isomer demands a reactor setup built to keep reaction pathways focused and limit side-product formation. The result? Tighter control over isomeric purity, fewer headaches for downstream processing, and a lower risk of cross-reactions in custom synthesis work.

    Clients who once used commodity-grade di- or tri-chlorobutanes often switched to targeted isomers like ours after running into issues with reactivity clashes or off-target byproduct generation. We've learned from years on the reactor line that each isomer brings its own strengths, and that even subtle shifts—like moving both chlorides off the terminal positions—bring new selectivity. Technicians in our facility tune batch times, catalyst choices, and separation parameters to favor the 2,3- isomer, giving us on-the-ground feedback about what setups actually minimize byproducts and improve ease of scale-up.

    For those unfamiliar, 1,2- and 1,4-Dichlorobutanes have long histories in industry, but carry drawbacks in some reactions—where selectivity or ease of purification matters. 2,3-Dichlorobutane’s unique structure means it reacts differently with alkali, nucleophiles, or transition metal catalysts. Each year, as analytical requests became more customized, we refined distillation and GC methods specifically to catch trace isomers or related halides, since we knew from talking to end-users that even low-level impurities sometimes spiked reaction costs or reduced yields.

    Handling, Packaging, and Product Life—As Seen by Producers

    Nothing beats seeing the packaging drums lined up ready for shipping. Every container sealing, every drum label, every lot trace—the small steps build real trust when clients use our dichlorobutane in sensitive settings. We’ve invested steadily to keep our containers free from rust, unwanted residues, and moisture pick-up, and always check for airtight closures and chemical resistance before items leave the plant. Staff monitor warehouse environmental controls year-round, since shifts in temperature and humidity impact how well the product ages and avoid any risk of drum swelling or inner liner disruption.

    These are not minor concerns. We learned the hard way early on that poorly maintained storage leads to compound degradation, especially for sensitive halogenated intermediates like 2,3-Dichlorobutane. We've since trained our logistics people on hands-on inspection—checking both interior and exterior before, during, and after the filling, so neither oxidation nor cross-contamination creeps in. Even small trace amounts of previous contents or lining plastics breaking down can show up on a detailed assay, and we've taken steps to cut these risks to nearly zero.

    Clients working on scale-up or multi-tonne syntheses appreciate transparency about every step between plant and delivery site. We open up our plant workflows, allowing audits when needed and always supplying real photographic records of filled containers, not just paperwork. It’s become clear over the years that trust is earned with trackability at every handoff—from production tank to shipping vehicle to customer door.

    From Batch Control to Application Support: Insights Only Manufacturers Possess

    Thinking about lab synthesis, research teams care about predictable properties and hassle-free scale-up. That requires more than a standard purity certificate. Our plant records, going back years, allow us to troubleshoot batch anomalies, adjust conditions based on client feedback, and supply detailed impurity breakdowns every time someone requests them. We don’t just follow the regulations; we talk directly with users conducting pilot reactions or scale-up runs, integrating their findings into our ongoing tweaks in manufacturing.

    Over time, we expanded our application support desk with real chemists—people who’ve run the reactions themselves, not just read about them. The feedback loop is fast: if a customer reports an issue with a minor impurity, our QC and technical teams pull the batch, rerun detailed analytical profiles, and work through solutions in parallel. More than once, this direct channel helped patch small gaps in our process before they could grow into real problems.

    Our experience touches the full supply chain, from raw material sourcing to ready-to-use compounds. Some competitors source off-the-shelf intermediates, blend to spec, and resell—a shortcut exposed when unusual specs or demands come up. As real manufacturers, we adjust actual reaction conditions, adapt or improve purification steps, and stand behind our quality downstream. That hands-on commitment means no batch leaves our plant without confidence from our own operators, not just a remote supplier.

    Current Trends, Market Demands, and Real-World Reliability

    Through regular industry dialogue, user group sessions, and feedback from R&D, we know the landscape around chlorinated intermediates keeps shifting. Today’s buyers run leaner research groups, batch sizes fluctuate, and legislative focus on trace impurities tightens every season. Our team feels these trends directly on the production floor, so we upgrade our emission control, push for greener synthesis, and partner with groups aiming for cleaner, safer chlorine use.

    It’s clear that the old days of “one purity fits all” don’t serve clients looking for reliable intermediates in such a fast-evolving space. Some need a variant with microchloride specs for catalyst compatibility. Others require clear documentation to satisfy environmental audits. We've learned the value in maintaining batch record depth, offering fast turnover on custom-confirmed quality, and backing up claims with real technical data, not just sales promises.

    Challenges and Solutions: Direct Answers from the Source

    Reliable dichlorobutane production throws up challenges, from supply chain swings in precursor chemicals to day-by-day tweaks in reactor conditions. We saw first-hand how disruptions in upstream chlorine supply rapidly impact final output—so we built redundancies, diversified sourcing, and committed early to keeping a real buffer inventory on-site. This logistical discipline didn’t just help our own line; it helped partners hit deadlines during volatile periods, whether for research tons or multi-tonne commercial needs.

    Achieving precise purity profiles remains a technical challenge, especially when customers call for even tighter residual or metal traces. We invest in modern chromatographic and spectroscopic instruments, and we don’t outsource these controls. In several projects, purity specs demanded cross-validation by different methods—gas chromatography plus NMR and mass spec—to hit thresholds under one part-per-thousand. Having the capability in-house, run by our staff, lets us catch problems faster and tune production without delay.

    Our staff keeps a focus on continuous improvement—not just to satisfy audits, but because our own peace of mind rides on knowing each batch stands up to scrutiny. Our operators contribute process insights, our lab staff flag emerging impurity risks, and our technical team meets regularly with customers to shape next-generation specs. Upgrades to filtration, reaction venting, and waste control are often the result of these joint efforts.

    Safety, Environmental Considerations, and Responsible Production

    Running large-scale halogenation demands an uncompromising approach to safety—personnel, facility, and downstream impact. We put a premium on detailed operator training, regular facility audits, and full containment of both reactants and finished batches. Odors or chlorinated fumes are intercepted at source, with air handling and scrubbing systems field-proven under actual plant loads. Residuals and waste streams undergo neutralization per environmental norms, long before local regulations caught up.

    The broader push within chemicals demands clear documentation, safety data support, and traceability back to batch source. Every shipment carries its true production code, linked to logging at every handling stage. This wasn’t just a compliance step—clients, especially those in pharma or food chain intermediates, require unbroken verification spanning years. As producers, this level of traceability reassures both us and our partners that accountability isn't just paperwork.

    Ongoing laboratory R&D in our group helps replace older chlorine-heavy routines with modern, more sustainable alternatives wherever practical. Steps like solvent recovery, effluent recycling, and reduced-waste synthesis have become regular talking points in both internal audits and external client updates. We bring these improvements to market as soon as they’re tested for reliability, knowing that the next generation of chemical buyers expects more environmentally-sensitive production.

    Conclusion: Putting Experience to Work for Every End User

    2,3-Dichlorobutane may look simple on a molecular diagram, but real-world manufacturing brings a world of intricacy. Every drum and every batch carries not only the result of a controlled reaction, but also the weight of years spent refining, measuring, contacting, and troubleshooting with hands-on expertise. Our team believes real trust comes from direct, transparent relationships, and we have built our business not on push sales tactics, but on clear communication and responsible action from start to finish.

    Anyone sourcing 2,3-Dichlorobutane for serious application, from specialty synthesis to large-scale formulation, needs to know the difference a real manufacturer provides. We’ve shaped our processes, equipment, documentation, and culture around one goal: reliability built on experience. By drawing on the lessons learned through years of chemical production, we stand ready to not just supply, but partner with users who demand more from their chemical building blocks.