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2,3-Dichlorobenzotrifluoride

    • Product Name 2,3-Dichlorobenzotrifluoride
    • Alias DCBTF
    • Einecs 215-606-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    617773

    Cas Number 2845-21-6
    Molecular Formula C7H3Cl2F3
    Molar Mass 215.00 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Aromatic
    Boiling Point 174-176°C
    Melting Point -14°C
    Density 1.46 g/cm³ at 20°C
    Solubility In Water Insoluble
    Flash Point 61°C (closed cup)
    Refractive Index 1.502 at 20°C
    Vapor Pressure 0.6 mmHg at 25°C

    As an accredited 2,3-Dichlorobenzotrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 2,3-Dichlorobenzotrifluoride is packaged in a 500 mL amber glass bottle, with secure cap and hazard labeling.
    Shipping **Shipping Description for 2,3-Dichlorobenzotrifluoride:** This chemical should be shipped in tightly sealed containers, away from heat and incompatible materials. It is classified as hazardous for transport, typically under UN 3082, Environmentally Hazardous Substance, Liquid, N.O.S. Appropriate labeling, documentation, and compliance with local and international regulations are required.
    Storage 2,3-Dichlorobenzotrifluoride should be stored in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers and acids. Keep containers tightly closed and properly labeled. Store away from heat sources, sparks, and open flames. Use corrosion-resistant containers and ensure secondary containment to prevent leaks or spills. Avoid direct sunlight and minimize exposure to moisture.
    Application of 2,3-Dichlorobenzotrifluoride

    Applications of 2,3-Dichlorobenzotrifluoride in Industrial Manufacturing

    As a direct manufacturer, we provide 2,3-Dichlorobenzotrifluoride for specialized industrial sectors where controlled quality, regulatory adherence, and precise formulation are essential to downstream production outcomes. Below, we outline its confirmed downstream industrial uses, with detailed scenario-specific requirements, process, and product information.

    1. Agrochemical Intermediate Synthesis

    In crop protection manufacturing, 2,3-Dichlorobenzotrifluoride serves as an essential halogenated aromatic intermediate for synthesizing select herbicides and fungicide actives—particularly where electron-withdrawing groups improve bioactivity and environmental stability. Downstream formulators depend on its reactivity in etherification or amination reactions to construct complex actives with controlled substitution patterns. Its role is non-interchangeable due to the specific aromatic configuration required in certain fluorinated phenoxy or anilide compounds. Manufacturing sites prioritize traceability and impurity profiling to satisfy agricultural chemical registration protocols.

    Industry compliance standards

    • OECD Good Laboratory Practice (GLP)
    • REACH Regulation (EC) No 1907/2006
    • FAO/WHO Guide to Specifications for Agricultural Pesticides
    • ISO 9001:2015 Quality Management for Agrochemical Manufacturing

    Typical usage ratio

    • Concentration in synthesis: 0.5–1.2 molar equivalents based on target active molecule; actual proportion depends on the desired substitution pattern and efficiency of downstream coupling.

    Downstream process integration

    • Enters as a key aromatic reactant in condensation or nucleophilic aromatic substitution steps; introduced after initial etherification/amination batch preparation but before final quench/purification.

    Final product types

    • Fluorinated phenoxy herbicides
    • Aromatic anilide fungicides
    • Intermediate stock solutions for crop protection actives

    2. Pharmaceutical Intermediate Manufacturing

    Original drug substance and active pharmaceutical ingredient (API) synthesis operations incorporate 2,3-Dichlorobenzotrifluoride as a halogenated aromatic synthon when constructing complex pharmaceutical scaffolds. Medicinal chemists use it for introducing stable trifluoromethyl motifs and dihalogen substitution into advanced intermediates, often via selective cross-coupling or Friedel–Crafts reactions. Batch QA/QC tracks residuals stringently due to strict pharmacopeia limits for halogenated process impurities.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for APIs
    • United States Pharmacopoeia (USP) General Chapter <467> Residual Solvents
    • European Pharmacopoeia (Ph. Eur.) monograph compliance
    • FDA 21 CFR Part 211

    Typical usage ratio

    • Introduced at 0.8–1.5 molar equivalents depending on the specific coupling strategy and yield optimization for each API intermediate.

    Downstream process integration

    • Dosed as the aromatic halide source during multi-step organic synthesis, especially in Grignard, Suzuki, or Buchwald–Hartwig reactions, positioned before key scaffold assembly or ring-closure operations.

    Final product types

    • Halogenated small molecule API intermediates
    • Advanced pharma research intermediates
    • Pilot-scale batches for final API synthesis validation

    3. Specialty Coating and Polymer Additive Manufacturing

    In high-performance polymer and coatings manufacture, especially for electronics and aerospace materials, 2,3-Dichlorobenzotrifluoride acts as a monomer precursor and performance additive. Its unique halogen/trifluoromethyl structure introduces hydrophobicity and chemical resistance to polyarylene ether and polyimide matrices. Resin formulators introduce the raw material at strictly controlled ratios to tune the dielectric and barrier characteristics—critical for insulating films, conformal coatings, and high-frequency PCB substrates.

    Industry compliance standards

    • UL 94 Flammability Standards
    • RoHS 2011/65/EU Directive for Electronics
    • REACH Authorisation Requirements for Monomers/Additives
    • ASTM D3159 for Polyimide Materials

    Typical usage ratio

    • Polymerization additive loading: 1–4% w/w relative to base monomer system; level varies based on final dielectric or mechanical property requirements.

    Downstream process integration

    • Introduced during prepolymer synthesis or directly into resin blending tanks; sequence depends on desired copolymer distribution and reactivity offset during initial mixing or in-situ polymerization steps.

    Final product types

    • High-durability insulating coatings
    • Electronic-grade polyimide films
    • Specialty fluorinated resins for printed circuit boards

    4. Fine Chemical and Dye Intermediate Production

    Producers of specialty dyes and fine chemical intermediates utilize 2,3-Dichlorobenzotrifluoride to introduce trifluoromethyl and halogen substituents into aromatic backbones, which enhances lightfastness and thermal stability for industrial dyes and pigments. Chemical synthesis teams add the compound at key substitution stages to reach the required shade intensity and performance characteristics, with strict control measures on impurity carryover and residual solvents for downstream colorant manufacturing.

    Industry compliance standards

    • ISO 9001:2015 for Colorant Manufacture
    • EN 71-3 Safety of Toys—Migration of Certain Elements (for dyes used in toys)
    • REACH Annex XVII for hazardous aromatic amines (dye manufacturing compliance)
    • ZDHC MRSL for restricted substances in textile applications

    Typical usage ratio

    • Applied at 0.4–1.0 mole equivalents, adjusted according to desired degree of substitution and targeted chromophore profile in final dye products.

    Downstream process integration

    • Fed into chlorination, sulfonation, or coupling stages during multi-step dye precursor synthesis, introduced after initial base formation to form color-imparting substituents.

    Final product types

    • Disperse and acid dyes for polyester and nylon
    • Trifluoromethylated chromophores for specialty pigments
    • Fine chemical intermediates for further colorant synthesis

    5. Liquid Crystal Intermediate Supply for Display Manufacturing

    In display technology manufacturing, advanced liquid crystal material producers use 2,3-Dichlorobenzotrifluoride as a source of halogenation and fluorination during the synthesis of terminal and lateral substituents for high-performance mesogens. Engineering-grade liquid crystal intermediates require precise control in purity and substitution pattern since minor contaminants can affect phase transition and electro-optic behavior. Material handlers dose the compound in custom synthesis batches dedicated to the fabrication of specific nematic or smectic liquid crystal mixtures for TFT-LCD and OLED panels.

    Industry compliance standards

    • IEC 61249-2-21 Halogen-Free Materials Standards
    • RoHS Directive for display material compliance
    • JEITA ET-7304 Standard Specification for Liquid Crystal Compounds
    • ISO 14001:2015 Environmental Management for electronics chemicals

    Typical usage ratio

    • 0.8–1.1 equivalents in fine chemical synthesis, depending on final mesogen core symmetry and target transition temperature.

    Downstream process integration

    • Supplied at the coupling or halogen-exchange phase in oligomeric and monomeric liquid crystal material synthesis, typically preceding final purification and mixture blending.

    Final product types

    • Customized nematic and smectic liquid crystal mixtures
    • Advanced organic intermediates for display panels
    • Performance enhancers for OLED and TFT-LCD devices
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    Certification & Compliance
    More Introduction

    2,3-Dichlorobenzotrifluoride: Proven Value for Modern Chemical Synthesis

    Decades of Experience with a Versatile Intermediate

    Standing in a production facility, you see how every drum of 2,3-Dichlorobenzotrifluoride, sometimes called 2,3-DCBTF or DC-23, represents more than purified liquid. For us, crafting this molecule isn’t just chemistry. It’s the result of long-term process refinement and a deep respect for what downstream chemists need. With the CAS number 811-59-8, this compound consistently performs where technical reliability and purity can’t be compromised.

    Molecular Details Make the Difference

    2,3-Dichlorobenzotrifluoride, with the formula C7H3Cl2F3, contains both dichloro and trifluoromethyl functionalities on a benzene ring. These groups are not just add-ons. After many years watching process outcomes, it’s clear their combined reactivity unlocks paths that aren’t open with the more common mono-chlorinated or non-fluorinated benzotrifluorides. What comes out of our reactors doesn’t just tick boxes for physical properties – it gives you a head start for robust, selective transformations.

    How Real-World Demand Shapes Quality

    Whether a customer works in crop protection, specialty resins, or high-performance coatings, we see how mishandled composition causes downstream headaches. On our side, it means investing in tight analytical verification before each shipment leaves the gate. Hydrogenation, halogen exchange, and nucleophilic aromatic substitution steps play out more efficiently when contaminants or variable isomer ratios do not distract your operators or researchers.

    Our technical teams have seen enough pilot runs and full-scale batches to recognize that even slight impurities bleed through synthesis chains. Consistency beats theoretical numbers. The purity customers commonly need sits above 99%, with isomeric mixtures strictly controlled. We rely on proven purification steps and constant GC analysis, not just batch documents stuffed in archives. Scale-up from pilot reactors to main line vessels does not change our standard for quality.

    What Sets 2,3-Dichlorobenzotrifluoride Apart from Similar Compounds

    It pays to compare. Some users ask about 2,6-dichloro, 3,4-dichloro, or the mono-chloro versions of benzotrifluoride. Over time, side-by-side trials and customer feedback leave no doubt: 2,3-DCBTF often shows best-in-class reactivity in coupling reactions and halogen-metal exchanges, especially when ortho and meta positions are critical. The presence of chlorine atoms in the 2 and 3 positions changes how electron density flows through the ring. It encourages selectivity in certain nucleophilic aromatic substitutions, a feature synthetic chemists appreciate in scale-up. The –CF3 group, not just another electron-withdrawing ornament, boosts chemical and thermal stability, directly impacting yields of advanced intermediates.

    Some downstream syntheses reject alternatives such as 4-chloro or 2,4-dichlorobenzotrifluoride due to differences in reaction sites and resistance to undesired side reactions. Then there’s process safety: the boiling point and vapor pressure make our 2,3-DCBTF not only easier to recover by distillation, but also safer to handle in ventilated systems than certain lower-boiling aromatics.

    Where Downstream Transformations Find Mileage

    New molecules rarely travel a straight path from theory to meaningful products. Glyphosate analogues, fluorinated agrochemical intermediates, and high-value liquid crystal materials have all called for 2,3-DCBTF at some stage. Customers building complex benzotrifluoride scaffolds see the difference in their chromatography results and isolation steps. We’ve talked to teams working on cross-coupling, Grignard extensions, and even tailored biocide precursors who return for consistent supply. Their choices help us tune purification targets even tighter with each campaign.

    Every plant manager knows cost containment doesn’t start at the last synthetic step. Downstream reaction rates, work-up simplicity, and product stream management all depend on the starting compound’s purity and predictability. When a reaction mix includes an outlier isomer or micro-level byproduct, purification costs jump and production targets slip. Experience has taught us to focus on reliable isolation right at the source, so our customers aren’t cleaning up after someone else’s shortcuts.

    Supporting Core Industries in Practice, Not Theory

    Our 2,3-dichlorobenzotrifluoride grew up in the trenches of the world’s largest chemical economies. Agriscience facilities call for hundreds of kilograms per campaign; electronics developers order drums in small lots for novel fluorinated materials, where downstream performance matters more than a spec sheet. High-quality 2,3-DCBTF enters these plants, not just as a commodity but as a key gatekeeper— everything built on top depends on this foundation.

    Our role as a producer looks outward. We see customers move rapidly from feasibility trials to multi-ton operations, then request the stability and flexibility only a direct manufacturer offers. They explain what works, what blocks progress, and what could improve. Pressure from production deadlines and regulatory shifts puts theory to the test, and only robust supply relationships align with real-world manufacturing.

    Environmental, Health, and Regulatory Duties: Embedded In Every Batch

    We produce 2,3-DCBTF inside closed systems, using all means possible to minimize fugitive emissions and worker exposure. Our R&D team constantly evaluates greener process steps and end-of-life control pathways. They do not treat this as a tick-box exercise for compliance, but address root process sources to lower the environmental load.

    As environmental limits tighten, we no longer see waste management as an afterthought. We pre-empt new regulations by building analytical and treatment redundancies into our process plant. Discharge streams pass through multi-stage neutralization and advanced carbon filtration, measured with continuous monitoring. Operators have direct hotlines to environmental managers, so even a minor out-of-range can be spotted long before regulators knock.

    Handling guidelines draw on decades of lessons—not just from our paperwork, but honest post-mortems on global incidents. We supply detailed, practical instructions passed down through our plant teams. The result: safer material for all hands, from bulk unloading to small-scale sampling in the lab.

    Collaborating with Innovators, Not Just Filling Orders

    For every kilo we ship, there’s a research group or a scale-up engineer on the other side figuring out how to build value further down the line. We get frequent requests for blends with controlled isomer ratios, specialty packaging to reduce air exposure, and custom documentation that regulatory managers can trust. Years ago, only the largest buyers pushed for these changes. Now even small-batch R&D teams apply pressure, and that’s good for everyone.

    Technical exchanges with our customers drive practical changes. They explain where competitive alternatives fail—solubility, color stability, contamination with similar isomers—then expect us, as manufacturers, to take action. Downstream failure rates drop best when raw material quality problems never make it into the process plant in the first place.

    Analysis can’t only chase after-the-fact complaints. Informed by customer feedback and independent audits, our lab routines tighten with each production run. If a problem turns up, action follows at the plant. This commitment turns “repeat order” from a buzzword to a shared target.

    Process Evolution: Responding to the Push for Sustainability

    Chemical manufacturing faces intense pressure: efficiency, safety, and sustainability. To survive and grow, we’ve upgraded plant assets, cut water usage, and scavenged heat waste at every opportunity. Our experience shows long-lasting supply partnerships beat short-term margin wins—waste not only loads landfills, but clogs reactor jackets and drains value at every turn.

    We’ve moved away from older, harsher process steps. In-process monitoring keeps formation of unwanted side-products at bay, limiting off-spec runs and reducing the need for post-processing. These changes no longer sit in the “R&D phase”—they impact production scheduling, batch consistency, and overall throughput.

    Working closely with global customers, we respond to demands for less halogenated runoff and easier waste segregation after use. Constant dialogue with formulators prompts us to create more detailed Certificates of Analysis—with tighter, relevant limits rather than useless standard templates. Downstream, this cuts back headaches for every operator who handles material we produce.

    Comparing Sourcing: The Manufacturer's Edge

    As direct producers, we control process and logistics from precursor sourcing to finished drum. Third parties offer catalog convenience, but the bumps in consistency, documentation, or delivery often trace right back to lacking transparency. Problems from cut corners rarely go away by doubling quality checks at the point of use.

    Operating reactors and distillation lines teaches you quickly: what walks out of the plant door represents your reputation. Specials, trial batches, and packaging tweaks put our promises to the test. If an innovation works, we incorporate it factory-wide. If not, it’s shelved and lessons are shared backward through operations, not buried in memos.

    Our logistics teams sync with our process crews, so customers don’t wind up explaining to their regulators that a missed delivery is “someone else’s problem.” That’s why consistency, traceability, and accountability remain non-negotiable.

    Demands from Industry: Not Just Meeting, But Anticipating

    We see daily requests from customers seeking to cut cycle time, raise conversion rates, and reduce environmental impacts. By working closely with those tackling condensation reactions on the factory floor, or cleaning reactor trains after a stubborn batch, we don’t forget practicalities that can be lost in academic literature.

    Requests for better packaging, custom batch sizes, and tailored documentation reflect genuine needs, not marketing spin. Instead of pressing the same solution on everyone, we listen, learn, and adapt production to what each industry phase requires. That’s helped us evolve our offerings for large-scale multi-ton deliveries as well as smaller, agile R&D streams in pilot plants or scale-up labs.

    For each field—crop protection, specialty fluorochemicals, advanced materials, or electronics—we’ve worked through hundreds of batch campaigns, each one teaching lessons the next customer benefits from. Those relationships, often built over years or decades, mirror the stability of the molecules we put in drums.

    Continuous Learning: Keeping Customers and Production Aligned

    We don’t rest on routine. Each campaign of 2,3-Dichlorobenzotrifluoride benefits from feedback loops—customer phone calls, process audits, and the onsite experience of our operators. Adjustments happen right in the plant, not just in response to audit checklists. If an impurity pops up in the stream, we address it at source—not with band-aid fixes, but by refining purification or raw material supply.

    Operational teams take pride in their craft. Knowing the stakes, they test, record, and review at every step. This attention to detail comes from thousands of hours on the shop floor, seeing what works and owning the results if something doesn’t. Every operator knows: what’s loaded into a drum today becomes tomorrow’s breakthrough or setback in the customer’s site.

    Conclusion: Why 2,3-DCBTF Matters, and Why Direct Production Counts

    In our experience, the role of 2,3-Dichlorobenzotrifluoride goes far beyond being a building block. The technical advantages of the 2,3-substitution pattern, the reliability of our manufacturing processes, and the feedback-driven improvements sustained by real-world users all matter. Each drum, each campaign, and each support call forms a chain that delivers more efficient, more predictable results for the chemical innovators shaping the next generation of products. For us, producing this compound remains both a craft and a shared responsibility—a role we take seriously, batch after batch.