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2,3-Dichloro-1-Propanol

    • Product Name 2,3-Dichloro-1-Propanol
    • Alias 2,3-DCP
    • Einecs 202-491-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    358305

    Chemicalname 2,3-Dichloro-1-Propanol
    Casnumber 616-23-9
    Molecularformula C3H6Cl2O
    Molarmass 129.99 g/mol
    Appearance Colorless to pale yellow liquid
    Boilingpoint 174-176°C
    Meltingpoint -34°C
    Density 1.36 g/cm³
    Solubilityinwater Miscible
    Refractiveindex 1.462
    Flashpoint 78°C

    As an accredited 2,3-Dichloro-1-Propanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 500 mL of 2,3-Dichloro-1-Propanol, sealed with a secure cap, labeled with hazard and handling instructions.
    Shipping 2,3-Dichloro-1-Propanol should be shipped in tightly sealed, chemical-resistant containers, compliant with hazardous material regulations. It must be labeled with proper hazard warnings and transported in accordance with local, national, and international guidelines. Protect from heat, direct sunlight, and incompatible substances. Ensure upright positioning and secure packaging to prevent leaks.
    Storage 2,3-Dichloro-1-propanol should be stored in a tightly closed container in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and acids. Keep away from direct sunlight and moisture. Store at room temperature and follow all relevant local, state, and federal regulations for hazardous chemicals. Use secondary containment when possible.
    Application of 2,3-Dichloro-1-Propanol

    Applications of 2,3-Dichloro-1-Propanol in Industrial Manufacturing

    2,3-Dichloro-1-propanol serves as a critical intermediate across multiple fields of chemical manufacturing. As a direct producer, we supply this key material to various industry partners relying on specialized compliance, formulation accuracy, and integrated process steps to support demanding application requirements.

    1. Pharmaceutical Intermediate Synthesis

    Pharmaceutical manufacturers employ 2,3-dichloro-1-propanol as a building block for active pharmaceutical ingredient (API) synthesis, including anti-infective and anticancer molecules. It frequently functions as a halogen-containing moiety in multi-step organic syntheses. Customers monitor incoming raw material QC tightly to control impurities at each conversion stage. Compliance with pharmacopeia monographs and strict supplier audits are standard due to direct downstream use in high-purity APIs.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • USP-NF (United States Pharmacopeia–National Formulary) for intermediates
    • EudraLex Volume 4 (EU GMP Guidelines)
    • Drug Master File (DMF) submissions—US FDA

    Typical usage ratio

    • Varies by synthesis: 0.8–1.3 molar equivalents per API batch, adjusted based on target molecule and reaction pathway

    Downstream process integration

    • Enters as a chlorinated carbon source in nucleophilic substitution or coupling reactions
    • Phase transfer catalysis or batch reactors integrate the intermediate during early to mid-stage synthesis
    • Real-time chromatography tracks conversion and byproduct removal

    Final product types

    • Cephalosporin antibiotics
    • Alkylating agents for oncology
    • Intermediates for cardiovascular and anti-inflammatory APIs

    2. Agrochemical Technical Production

    2,3-Dichloro-1-propanol acts as an intermediate in the synthesis of certain herbicide and fungicide actives. Agrochemical plants use this material to introduce chloroalkyl groups during active ingredient construction, driving selective reactivity in downstream synthesis. Regulatory compliance prioritizes traceability for all lots entering crop-protection manufacturing, with environmental and residue standards strictly monitored.

    Industry compliance standards

    • FAO/WHO Specifications for Pesticide Active Ingredients
    • ISO 9001-certified production and traceability
    • EU Regulation (EC) No 1107/2009 for plant protection products
    • REACH Registration for raw material transport and use

    Typical usage ratio

    • 0.9–1.2 molar equivalents per technical active batch, depending on target formulation complexity and crop origin requirements

    Downstream process integration

    • Introduced during early-stage alkylation, chlorination, or condensation reactions in synthesis of actives
    • Handled in closed reactor systems with in-line HPLC monitoring of conversion
    • Waste streams treated for chlorinated organic residuals per environmental permit

    Final product types

    • Chloroalkyl-substituted fungicides
    • Herbicide intermediates for cereal and rice protection
    • Selective pre-emergent compounds

    3. Epoxy Resin and Polymer Intermediate

    Specialty resin producers use 2,3-dichloro-1-propanol as a raw material for synthesis of modified epoxy resins and specialty monomers, supporting development of industrial coatings and engineered plastics. The compound provides tailored reactivity for controlling chain length and cross-link density in final polymers. Batch-to-batch consistency is critical to ensure predictable mechanical and chemical properties in resin systems.

    Industry compliance standards

    • ISO 9001-certified Quality Management Systems
    • RoHS Directive (2011/65/EU) for restricted substances
    • REACH Regulation (EC) No 1907/2006
    • UL 94 Flammability rating for electrical-grade resins

    Typical usage ratio

    • 5–15% by weight in reaction blends, ratio varies based on targeted crosslinker density and molecular weight requirements of the specific resin system

    Downstream process integration

    • Dosed during prepolymer synthesis as a reactive diluent or halogen modifier
    • Fed as an intermediate in chain extension or copolymerization process steps
    • In-process viscosity and thermal stability testing required

    Final product types

    • Modified bisphenol-A and bisphenol-F epoxy resins
    • Halogenated flame-retardant epoxy coatings
    • Electrical encapsulants and potting compounds

    4. Fine Chemicals and Halogenated Solvent Synthesis

    Producers of specialty fine chemicals utilize 2,3-dichloro-1-propanol to generate structurally unique halogenated solvents, including derivatives used in synthesis, extraction, and formulation for electronics, adhesives, and surface finishing. The intermediate feeds directly into selective halogen exchange or reductive dechlorination steps. Precisely controlled input ratios and purification protocols assure the desired purity for sensitive electronic or specialty chemical applications.

    Industry compliance standards

    • ISO 14001 Environmental Management for chemical production
    • REACH Annex XVII for controlled category substances
    • Japanese Industrial Standard (JIS K 6251) for electronic chemical purity
    • GHS chemical labeling and transport safety

    Typical usage ratio

    • Ranges from 10–30% by weight in halogen-exchange processes, proportion based on desired chlorination level and application purity grade

    Downstream process integration

    • Acts as a controlled feed in halogenation, substitution, or reduction stages
    • Utilized in batch and continuous process reactors
    • Pilot-scale purification steps remove reaction by-products and ensure electronic grade quality

    Final product types

    • Halogenated extraction solvents
    • Chemical process intermediates for adhesives
    • Precision-cleaning agents for electronic assembly

    5. Surfactant and Specialty Chemical Ingredient Manufacturing

    Industrial surfactant formulators incorporate 2,3-dichloro-1-propanol for the preparation of certain functionalized nonionic or cationic surfactant intermediates. The compound yields reactive groups essential for tailorable solubility and wetting profiles, meeting the requirements for specialty cleaning, textile, and metal processing solutions. Precise adjustment of ingredient ratios allows surfactant manufacturers to match end-user performance in regulated downstream applications.

    Industry compliance standards

    • ISO 14001 for environmental responsibility in chemical blending
    • OECD Guidelines for Testing of Chemicals (ecotoxicity evaluation)
    • REACH-compliant safety data documentation
    • Wilhelmy Plate and ASTM D1331 test procedures for surfactant characterization

    Typical usage ratio

    • 1–8% by weight in surfactant precursor synthesis, tuned based on hydrophilic-lipophilic balance target and corresponding product viscosity

    Downstream process integration

    • Added as a functionalizing agent during intermediate synthesis prior to quaternization or ethoxylation
    • Continuous or fed-batch reactor processes apply the ingredient at controlled temperature and agitation parameters
    • Surfactant activity and foaming index measured in-line

    Final product types

    • Modified nonionic surfactants for textiles and detergents
    • Cationic surfactants for metalworking fluids
    • Specialty process aids for emulsion polymerization
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    Certification & Compliance
    More Introduction

    2,3-Dichloro-1-Propanol: Trusted Performance from the Manufacturer’s Floor

    About 2,3-Dichloro-1-Propanol

    Stepping into the world of specialty chemicals, every manufacturer has a handful of building blocks that seem simple until their value becomes clear through use and consistency. 2,3-Dichloro-1-Propanol belongs squarely in that conversation. We look at C3H6Cl2O not just as a chemical formula on a bag, but as an everyday workhorse in many synthesis lines. Our customers run this product through their equipment because it shows up right every time, and that remains our priority. Delivering material with consistent purity, tailored to batch-specific results and transparent traceability underpin our operations, not only for compliance but because we’ve been on the receiving end of off-spec raw material, and nobody has patience for uncertain inputs.

    Our Model: Consistency and Transparency

    We put substantial effort into keeping every lot of 2,3-Dichloro-1-Propanol consistent in composition and performance. Each run we manufacture targets above 98% purity measured by GC, but more than hitting a number, our technicians follow protocols that evolved through repeated cycles and feedback from decades of partnership with industry leaders. Minor impurities or batch-to-batch inconsistencies have a habit of cranky side reactions and downstream inefficiencies. Anyone operating a production line—whether for pharmaceuticals, fine chemistry, or agrochemical intermediates—benefits from knowing exactly what’s made its way into their reactors. Our experience underlines the simple fact: Consistency does not happen by accident. It’s the direct result of process engineering, skilled oversight, and real-time adjustments as small as calibrating a distillation head or cleaning a condensation trap.

    Specifications That Matter in Practice

    In daily plant operations, yield and selectivity dictate a project’s success. For 2,3-Dichloro-1-Propanol, ensuring water content remains below 0.3% keeps the unwanted hydrolysis at bay. Controlled chlorine content and the absence of unsaturated byproducts remove downstream guesswork for those involved in further transformations, especially in epoxide synthesis or chlorohydrin intermediate work. Our commitment goes past the minimum specs—customers draw samples directly from drums on delivery, and those samples match the certificates. If they don’t, the lot comes straight back, no debate needed. Our history in specialty organochlorine manufacturing means repeated investment in analytical support. Modern GC, Karl Fischer titration for water content, and FTIR for functional confirmation prove their worth each month as order volumes rise or customers run new product qualifications.

    Certain batches find their way into high-purity pharmaceutical campaigns, where trace residuals like allyl chloride content drop well below 50 ppm. For customers pushing processes sensitive to off-notes or color, we provide additional documentation on absence of colored impurities and test for clarity and haze. Batches going toward industrial-scale surfactant synthesis leverage less strict requirements, yet stability in volatility and shelf-life remain vital. We ship under inert gas whenever prolonged storage is needed, minimizing any chance for hydrochloric acid formation during transit or warehousing. Shipping and storage containers comply with international transit safety protocols, but our experience shows extra preventative measures pay off, especially on long-haul journeys through high humidity environments.

    Where 2,3-Dichloro-1-Propanol Succeeds

    In our facility, we’ve seen 2,3-Dichloro-1-Propanol pull more than its weight in several critical chemistries. George, one of our process engineers, likes to say, "It’s a handshake molecule: versatile enough to play both sides." It sits at a crossroads. In one lane, the molecule steps up as a precursor for fine chemical synthesis, especially where halohydrins pave the way to epoxides like epichlorohydrin. In another, it moves into the world of active pharmaceutical ingredients or even specialty resins. Years ago, someone in a European lab tried replacing a less predictable source material with our tailored chloropropanol, and their yield climbed north of 90%. This kind of grounded, production-side benefit is not some claim—it’s a conversation we’ve had over the phone more than once.

    We hear from teams scaling sulfonation or esterification steps—two industries notorious for fussiness over trace water and organic chloride content. Our efforts in controlling those very parameters began with listening to customer trials where the smallest impurity created downstream headaches. Such stories gave us a recipe for upstream purification that actually translates to real savings and fewer headaches during scale-up.

    Usage Applications: Stories from Practice

    Chemists across fields rerun syntheses with new lots, watching for missed endpoints and processing inefficiencies. Most commonly, 2,3-Dichloro-1-Propanol finds life as a reactant in epoxide production, agrochemical intermediate manufacturing, and certain pharmaceutical building blocks. Some of the more interesting calls we've fielded have been from research departments wanting to cut steps out of their process by leveraging chlorohydrin chemistry. Our own testing mimicked these approaches; shifting from alternative dichloropropanols, the yield through our route in select epichlorohydrin syntheses improves on average by at least 4%. Scale this up to several tons of production, and it adds considerably to throughput and cost stability.

    Another sector quietly relying on this molecule is the production of specialty surfactants and wetting agents. Here, uniformity in hydroxy and chloro substituents controls downstream saponification or sulfonation reactions. In rare but growing cases, 2,3-Dichloro-1-Propanol enters the flavor and fragrance intermediates market, where users outsize expectations on purity and character. We’ve worked with chemists in this field to bias the production parameters toward colorless and odor-neutral finished product. A more recent shift to green chemistry solutions means that downstream users increasingly want traceability not only for regulatory compliance but for carbon accounting. Our lot-by-lot records now provide lifecycle information extending all the way back to raw material sourcing.

    Key Differences from Other Products

    Many chemical companies offer chloropropanols. In our manufacturing line, separation of 2,3-isomer from other dichloropropanols remains a specialized step that goes beyond basic distillation. Some facilities push out mixed dichloro isomers as a single product to cut cost, but the performance gap shows up quickly for those with tighter reaction windows. Our plant, built to handle isomeric complexity, separates those variations so our 2,3-Dichloro-1-Propanol stands alone without ambiguity. Everything we ship gets its own certificate of analysis plus a supporting data package that traces each lot from raw material through final QA sign-off.

    For buyers currently using 1,3- or 1,2-Dichloro-1-Propanol, the substitution sometimes fails due to differences in reactivity at the molecular level. For example, the 2,3-isomer introduces unique selectivity where steric hindrance or positionally controlled reactions are required. We’ve supported process engineers transitioning formulations who needed finer control or higher selectivity—these changes directly affected margins and waste profiles for their plants. Over the years, we’ve seen lab managers discover they could avoid some side-product headaches just by specifying our higher-isomer-purity grade. Rather than splitting hairs over spec sheets, we invite customers to run those pilot-scale tests for themselves, sharing data openly when requested.

    Addressing Supply Chain and Quality Challenges

    Supply chain reliability separates a dependable chemical manufacturer from the rest. Shipping delays, raw material shortages, or drifting specifications once undermined key production cycles for our customers. Lessons learned from those disruptions led us to a robust, dual-source raw material strategy and investments in on-site QC. Our plant holds raw and finished inventory reserves sufficient to buffer 60+ days’ of regular output. We buy local where feasible but diversify across global suppliers for critical precursors. Extra quality checks on incoming materials keep surprises away, supported by an in-house lab running routine and custom tests as needed.

    Quality slips shut down production lines, so we adopted redundant final-stage verification protocols. Instead of waiting for customer audits to find gaps, our QA team pre-empts most issues by stress-testing production scenarios on simulated customer setups. Past audit reports from major multinationals cite our 2,3-Dichloro-1-Propanol lot data transparency as a deciding factor in contract awards. Those reports carry real weight in our ongoing improvement cycles—what shows up in a lab notebook one quarter can directly translate to updated SOPs and finished product changes the next.

    A Responsible Footprint: Health, Safety and Environment

    Any chemical with multiple reactive sites deserves respect for worker safety and environmental protocol. Our direct handling experience shows that 2,3-Dichloro-1-Propanol poses irritancy and toxicity hazards unless fully contained and handled with appropriate PPE. Exposure controls, metered dosing setups, and modern ventilation mitigate much of the worker risk. Our team receives targeted training rooted in real case studies, not just regulatory checklists. Safe storage under nitrogen and temperature monitoring further reduce risk of unwanted degradation or build-up of pressure in storage drums.

    Waste streams, the perennial headache for any plant manager, require close attention here. Our approach captures chlorinated organics and routes them to in-house treatment facilities, neutralizing before safe discharge or high-efficiency incineration where required. We publish annual reports on solvent use ratios and recovery rates, holding ourselves accountable downstream. Environmental audits evaluate us on compliance, but our drive comes from seeing the effect of poor handling elsewhere. Even as regulations shift, we push our engineering team to raise the standard beyond statutory requirements. For every kilo delivered to a customer, we track final disposition and encourage downstream partners to follow best-practice waste minimization and recycling.

    Innovation and Collaboration in Chlorohydrin Chemistry

    As chemistries evolve, so do the demands placed on staple intermediates like 2,3-Dichloro-1-Propanol. Our R&D department keeps one hand on the pulse of new synthetic routes where this molecule might shorten reaction steps or improve atom economy. Recent collaborations with university teams led to discoveries in asymmetric syntheses, opening doorways for higher value derivatives previously out of reach. The feedback loop from our pilot plant and scale-up labs narrows the time between proof-of-concept and industrial reality. Our long-term customers benefit as we debug bottlenecks together, setting targets for even higher selectivity, alternative catalysts, or process intensification aimed squarely at productivity and downstream waste reduction. The willingness to experiment, plus open lines of communication, has allowed several pharmaceutical and agrochemical makers to pilot new processes at our site prior to pushing full production through their own chain.

    Regular workshops hosted at our site bring together our engineers and operators with customer technical leads. No one leaves without at least one experiment or side project worth deeper study, whether it’s trialing a new purification step, a shift in feedstock grade, or a method to reduce overall solvent burden. These cooperative sessions shape ongoing investment in plant upgrades, analytics, and logistics for 2,3-Dichloro-1-Propanol, reflecting collective expertise, not just an internal roadmap. The product you see listed for sale carries that legacy—a dynamic and informed effort to make every drum live up to the reputation we have fought to establish.

    Upholding E-E-A-T: Experience, Expertise, Authority, and Trust

    Trust travels via word of mouth, but in chemicals, longevity and reliability are built batch by batch. Experienced plant operators and PhD-level chemists review each order, checking not only purity and compositional profile but functional compatibility with intended processes. Our ongoing requalification with multinational procurement teams demonstrates expertise valued by industry leaders. Having walked the lines ourselves, we recognize shortcutting at the source leads to expensive headaches downstream—that’s where our authority roots itself.

    We open our doors for external audits and encourage customers to visit our operation. Full records of each lot, from incoming feedstock through dechlorination or epoxidation steps, stand available for review. Transparency anchors our approach, and our team remains reachable to troubleshoot, answer technical questions, or provide in-depth documentation as regulatory and market landscapes shift. Our customers do not settle for abstract assurances or generic guarantees—a lesson learned through decades of hands-on collaboration. Their trust in our 2,3-Dichloro-1-Propanol comes from direct, continued experience.

    Outlook and Solutions for Tomorrow’s Needs

    Industry demands for 2,3-Dichloro-1-Propanol will continue to shift. We see the push toward even cleaner, more selective variants as reactions get pressurized by tighter specs and green chemistry directives. Customers advance requests for custom grades, or packaged solutions supporting closed-loop systems. Some shift their focus toward bio-sourced feedstock, while others look for footprint reduction via on-site container recycling or byproduct recovery.

    Our manufacturing priorities reflect those needs. We have invested in new reactor technology to better scale alternative routes and reclaim byproducts. Logistics systems now provide full visibility from real-time inventory to traceable shipping. As each phase of the supply landscape evolves, our experienced team adapts by rolling out updated specs, packaging, and services. The ability to offer pilot quantities and custom syntheses gives our customers room to run pilot projects or validate new processes quickly.

    With new regulations surrounding end-use and waste, regulatory landscape keeps evolving. We stay ahead by investing in internal regulatory expertise, technical partnerships, and membership in standards-setting bodies. Our technical bulletins keep customers informed, sharing hands-on findings before compliance deadlines force rushed decisions. As our operations grow, so too does our sense of responsibility—not just to deliver product, but to enable smarter, more resilient supply networks for all who depend on these vital building blocks. That’s the perspective you will always find in our work with 2,3-Dichloro-1-Propanol.