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HS Code |
104789 |
| Chemical Name | 2-(3,4-Dimethoxyphenyl)ethanol |
| Molecular Formula | C10H14O3 |
| Cas Number | 1687-27-8 |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 159-161°C at 13 mmHg |
| Melting Point | N/A |
| Density | 1.117 g/cm3 |
| Purity | Typically ≥98% |
| Solubility | Soluble in organic solvents like ethanol and DMSO |
| Smiles | COC1=CC=C(C=C1OC)CCO |
| Inchi | InChI=1S/C10H14O3/c1-12-9-4-3-8(5-10(9)13-2)2-6-11/h3-5,11H,2,6-7H2,1-2H3 |
| Storage Temperature | 2-8°C |
As an accredited 2-(3,4-Dimethoxyphenyl)Ethanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams of 2-(3,4-Dimethoxyphenyl)ethanol, tightly sealed with a tamper-evident screw cap. |
| Shipping | **Shipping Description for 2-(3,4-Dimethoxyphenyl)ethanol:** This chemical is packaged in tightly sealed containers to prevent leaks or contamination. It is shipped at ambient temperature with appropriate labeling for identification. The product should be handled according to standard chemical safety guidelines and protected from direct sunlight or extreme conditions during transit. |
| Storage | Store 2-(3,4-Dimethoxyphenyl)ethanol in a tightly sealed container, kept in a cool, dry, and well-ventilated area away from sources of ignition, heat, and direct sunlight. Avoid exposure to moisture and incompatible substances such as strong oxidizers. Ensure proper labeling, and use chemical-resistant materials for storage. Personal protective equipment (PPE) should be used when handling the chemical to avoid contact. |
Applications of 2-(3,4-Dimethoxyphenyl)Ethanol in Industrial Manufacturing2-(3,4-Dimethoxyphenyl)Ethanol plays a specialized role as a key intermediate in several downstream industrial applications. Its chemical structure supports targeted synthesis in pharmaceutical, fragrance, dye, and specialty chemicals manufacturing. As a direct producer, we focus on real-world industrial routes driven by regulatory requirements, precise formulation, and established process compatibility to ensure quality and consistency for high-value finished goods. 1. Pharmaceutical Intermediate for Antihypertensive API SynthesisMajor API manufacturers utilize this compound during multi-step synthesis routes to produce selective antihypertensive agents. It is introduced as a core building block in the hydrogenation or acylation stages, supporting the preparation of specific phenethylamine-based drugs under stringent GMP controls. The purity and fixed substitution pattern directly influence product quality, making the choice of raw material specification critical for batch validation and regulatory approval. Industry compliance standards
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2. Fine Fragrance Compound SynthesisLeading flavor and fragrance producers use this ingredient as a precursor during the synthesis of complex aromatic bases, specifically for luxury perfume accords and high-purity fragrance oils. The methoxy groups and aromatic character provide stability against oxidation and enable efficient coupling in the formation of aldehydic and musky olfactory notes, which are highly valued in the formulation of premium scent compositions. Industry compliance standards
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3. Organic Dye Intermediate ProductionGlobal dye manufacturers incorporate this raw material as a key intermediate when producing organic chromophores used in textile printing and specialty coatings. The electron-rich aromatic unit offers high reactivity in directed nitration and azo-coupling steps, enabling the synthesis of stable, lightfast dyes required for demanding end applications. Quality traceability along with color purity is ensured through tight raw material control at this stage. Industry compliance standards
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4. Specialty Polymer Additive ManufacturingAdvanced materials producers utilize this compound as a tailored modifier in the synthesis of functional polymers, especially where improved electrical insulation or UV stability is required. Its structural features allow it to act as a co-monomer or chain terminator under specific polycondensation and radical polymerization conditions. Strict QC protocols monitor incorporation efficiency and residual monomer content for specialized end-use compliance. Industry compliance standards
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5. Active Ingredient Precursor in Botanical Extract FormulationsNutraceutical and botanical extract manufacturers select this compound as a precursor for synthesizing potent phenolic antioxidants in their R&D-driven facilities. Its chemical profile enables straightforward esterification or glycosylation, facilitating the integration of stable polyphenolic compounds that pass food-grade safety and efficacy assessments. This approach supports product claims in dietary supplement and functional beverage segments under strict compositional analysis. Industry compliance standards
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2-(3,4-Dimethoxyphenyl)ethanol has earned a reputation among specialty chemical users for its consistency and distinctive profile. We produce this compound directly in our own integrated facility, so the quality at each stage—starting from raw material handling through to final packaging—remains under our direct supervision. Our chemists have spent years refining both the reaction conditions and purification routes, which sheds light on just how much minor variations in process control can alter the purity, reactivity, and downstream performance of this molecule.
Our production runs deliver 2-(3,4-Dimethoxyphenyl)ethanol at >99% purity by HPLC, with residual solvents and impurities regularly tested out at extremely low thresholds. Molecular integrity is checked batch by batch using GC-MS and NMR, and each drum receives a lot-specific certificate you can actually trace. We don’t rely on outside brokers or generic sources, so you won’t see cross-contamination with similar substituted phenylethyl alcohols—a problem that pops up when shortcuts or toll manufacturing dilute accountability.
Years ago, raw material inconsistencies caused headaches throughout the industry. Impurities from less rigorous syntheses led to unpleasant color or odor drift, which played havoc in applications like fragrance intermediates or pharmaceutical development where downstream catalysts act up in the presence of the smallest contaminant. We responded by upgrading filtration and implementing a double-crystallization step, which cut the false rejection rate to negligible levels and helped our partners run longer campaigns without batch-to-batch surprises.
This ethanol derivative sees daily use in two fields where trace monotonicity and chemical identity matter: as a building block in active pharmaceutical ingredient (API) synthesis, and as an intermediate for advanced fine fragrances. In API work, process chemists rely on oxidation and coupling reactions rooted in predictable aldehyde and alcohol group chemistry. Any hint of positional isomer or aromatic impurity risks invalidating an entire lot, so vertical control beats out third-party trading every day. Fragrance developers, who often scale up from gram to tonnage in response to global campaigns, see value in our rigorous documentation and shipping history, because it means repeatable results for every blend.
We’ve observed that subtle solvent residues—often ignored in loosely specified grades—cause persistent reactivity shifts in sensitive condensation or reduction steps, especially for researchers pushing toward new chiral centers. This pushes us to clean up both early and late-stage streams, which ironically also supports customers in analytical testing. Whenever a client calls about a reaction stalling unexpectedly, a close scan of the batch’s impurity fingerprint solves the mystery. Unlike brokers who collect and rebottle drums with little more than a hand test, our logs straight through production give answers grounded in hands-on process work.
Though the basic molecular structure links 2-(3,4-Dimethoxyphenyl)ethanol to other substituted phenyl ethanols, there are important functional differences tied to its reliability. Many traders cannot differentiate between the (3,4-dimethoxy) pattern and closely related isomers. We see this almost routinely in spot market procurement, where blended product batches can contain contaminants that disrupt both reactivity and regulatory documentation. Our approach keeps each intermediate line clear, with unique reactors reserved for individual syntheses and cleaning protocols that remove even trace carryover.
While some suppliers rely on direct extraction or under-optimized batch processing to keep costs down, our team has found that meticulous attention to catalyst ratios, moisture, and temperature at every stage creates a crystalline product free from tinges of gray or dusty odor notes. Outcomes in hydrogenation and ether cleavage procedures depend on this: over-alkylated or under-reduced fractions force repeat purification or, worse, yield inferior downstream results that users might not notice until process scale-up reveals the underlying faults.
Our legacy clients in Japan, Europe, and North America noticed right away that other sources left fine residues and required extra steps to ‘rezero’ reactors between product runs. Since moving to our dedicated line, companies found better yields and less downtime—facts borne out by their own pilot batch reports, which showed cleaner transitions and fewer “mystery” byproducts. This is not a result of generic “industry experience,” but of ongoing investment in air handling, in-line moisture removal, and process auditing.
Process operators need reliability, not theoretical promises. Over the years, we have seen how even the smallest shifts in raw material integrity can mean lost production days, regulatory headaches, or increased analytical spend. That is why we supply full analytical runs for every batch, invite plant managers to review our process records, and maintain open lines with our customer labs. Our teams consult directly with formulation R&D teams, not just procurement desks, because actionable feedback from actual users spurs improvements—such as reducing micro-residual halogen from upstream reactants which had stymied a biocatalyst project until we identified and reengineered the supplier link.
Many manufacturers tout batch numbers and COAs as “proof” of diligence, but we back it up with true supply chain visibility. Downstream, users can retrace each lot back to its point of synthesis, not just a rebottled IBC from an anonymous warehouse. If any doubt or question arises, our technical staff provides complete synthesis documentation—starting from AMS and sodium purity records to environmental controls in the drying phase. These records have stopped more than one costly recall for our pharma and food customers.
We also support clients scaling from research quantities to full commercial runs. Raw material continuity underpins the reliability needed for registration and regulatory filings. We proactively adjust our documentation and analytical support to meet either ICH, ISO, or local pharma guidelines based on customer requirements. By never splitting or pooling batches among facilities, every drum shipped retains its original data lines and analytical heritage, supporting full process validation without the complexity that mixed or traded materials bring.
We believe that chemical manufacturing isn’t just lab work—it is constant problem-solving under real-world conditions. Temperature swings, moisture drift, and even seasonal raw material shifts introduce variations that no datasheet can capture. Our operators understand that a textbook synthetic route for 2-(3,4-Dimethoxyphenyl)ethanol rarely fits the plant floor without adaptation. They’ve replaced textbook glassware syntheses with reactor modifications, upscaled drying cycles to match humidity loads, and debugged more crystallization issues than most chemists see in their entire careers.
Through experience, we learned what separates a batch that meets “specification” from one that fits a demanding pharmaceutical or fragrance process. For example, residue-free isolation takes long hours and operational patience—not wishful timetables. Unchecked micro-contaminants can pop up two or three process steps down the line, often at the point of final QC in the user’s own plant, causing unexpectedly high batch rejection rates. By focusing on the earliest possible removal of process impurities, we support our partners’ goals of higher conversion, longer catalyst life, and easier analytical sign-off.
We do not see the production cycle as a black box—over time, deeply engaged operators catch trends and share fixes with R&D. One spring, a trace off-odor crept into the product due to a seemingly minor change in local water supply. Lab testing caught the variation, traced it to a temporary uptick in sulfate, and flagged our engineering team, which changed pretreatment filters before supply was affected. To outsiders, these changes appear invisible; to an integrated producer, every outcome links directly to a chain of specifics in process stewardship.
Beyond market positioning, environmental controls and regulatory compliance have concrete implications for plants like ours working with aromatic alcohols. Waste streams from 2-(3,4-Dimethoxyphenyl)ethanol synthesis require special handling, so we invested in in-line stripping and condensate management, cutting both odors and waste moisture that can breach even tightly regulated emission limits. Auditors from European chemical agencies and multinational clients visit often, and our open record-keeping builds trust: what leaves our stacks and drains gets tracked to the decimal.
Industry regulation has become more challenging over the years. From REACH and TSCA to local waste codes, each batch faces stringent review and—especially in pharma buildup—traceability demands. To address this, every process adaptation undergoes risk assessment, and product safety teams work alongside line operators to keep documentation both accurate and timely. Process-level adjustments help us keep ahead of changing solvent limits and impurity thresholds, not merely responding to new regs but anticipating future requirements.
Years of direct client interaction drive home how a minor slip on documentation or impurity flags can cost not just money, but market access or even cause plant shutdowns. Addressing these risks means connecting plant and lab personnel so that every link in the chain supports not only product safety but uninterrupted supply for customers who depend on our reliability. We do not separate “quality” and “production” as two silos—the teams blend to solve problems, encourage feedback, and travel together for supplier reviews that directly shape our sourcing and process targets.
With every kilogram of 2-(3,4-Dimethoxyphenyl)ethanol produced, we recognize our role extends beyond what happens within our plant gates. Our chemists field requests from teams developing new pharmaceutical scaffolds or fragrances for global launches. Instead of offering a standard catalog product and moving on, we collaborate closely with formulation and process optimization groups—sharing side-by-side test data and, when a persistent challenge arises, inviting partners to audit our lab work or run joint trials.
In several recent cases, a customer’s in-process bottleneck boiled down to an impurity profile that only showed up in advanced analytical runs. Working together, we tweaked dehydration steps and adjusted reactor pressure cycles, directly improving crystallinity and flow properties. Such direct engagement sets apart a vertically integrated manufacturer from relabelers or traders, who often lack both the analytical data and the hands-on staff to offer process-specific fixes.
Emerging applications keep us learning: as researchers test new enzyme catalysts or scale up pilot processes, they depend on reproducible raw material input and tight impurity tracking. If deviations from target molecular weight distribution or unexpected byproducts emerge, our R&D team investigates root causes by leveraging both decades of archived data and new plant analytics. This builds mutual confidence that goes beyond simple product supply, fostering innovation both in our process and our customers’ end uses.
Day in and day out, our commitment to producing 2-(3,4-Dimethoxyphenyl)ethanol takes place on the plant floor, not just at the desk. We see customer priorities as directly tied to our own—if a batch lands with an unexpected impurity or lot swap, it falls on us to address it transparently and efficiently. Long years of chemical production experience inform our response: there’s always a focus on practical troubleshooting, not merely issuing another generic report or apology.
Raw materials pass through multiple hands in most traded supply chains, masking the original production practices. By keeping every step under one roof—sourcing, synthesis, isolation, finishing, and packaging—we minimize uncertainty at every link. Production teams work right beside analytical chemists, so feedback from users loops back rapidly for immediate process tweaks. Whether it’s a minor change to a filtration protocol or a broader effort to update reactor loading cycles, we ground everything in the needs expressed by those on the receiving end.
The story of our 2-(3,4-Dimethoxyphenyl)ethanol is one of ongoing improvement, prompted by the challenges our customers face every day. We grew through constant adaptation, facing new environmental rules, buyer demands, and process headaches head-on. This is not a faceless commodity; every batch carries the attention and know-how of those who built it from scratch and care about what it enables downstream. From API synthesis to cosmetics to advanced research, the reliability and deep characterization users experience come directly from production roots, not abstract “quality management” slogans, but by engineers and chemists who know that overlooked details mean real-world trouble.
Manufacturing 2-(3,4-Dimethoxyphenyl)ethanol is not just about reaching high yield or passing a final assay. It is about keeping pace with evolving industry standards, environmental needs, and end-user breakthroughs. Our doors remain open to feedback from all sides—R&D, procurement, safety, and regulatory—and those conversations drive every improvement, every innovation on both plant and customer side.
We stand by the perspective that specialty chemicals flourish only when made with strict attention to raw material integrity, open process control, detailed tracking, and real engagement with application chemists and process engineers. As users look to advance their fields, from medicine to advanced materials, they deserve more than commodity-grade inputs. The path to reliable chemistry runs straight through transparent manufacturing, where hands-on knowledge and continual learning shape every kilo produced and delivered.