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2,2-Dimethylsuccinic Acid

    • Product Name 2,2-Dimethylsuccinic Acid
    • Alias Methylsuccinic acid
    • Einecs 213-618-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    140623

    Cas Number 4984-01-6
    Molecular Formula C6H10O4
    Molecular Weight 146.14 g/mol
    Iupac Name 2,2-dimethylbutanedioic acid
    Appearance White crystalline solid
    Melting Point 122-124 °C
    Boiling Point Decomposes before boiling
    Solubility In Water Slightly soluble
    Density 1.29 g/cm³
    Pka 3.62, 5.53
    Smiles CC(C)(C)C(C(=O)O)C(=O)O
    Pubchem Cid 72019

    As an accredited 2,2-Dimethylsuccinic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2,2-Dimethylsuccinic Acid is sealed in a white plastic bottle with a tamper-evident cap and detailed labeling.
    Shipping **2,2-Dimethylsuccinic Acid** is shipped in tightly sealed containers, protected from moisture and incompatible substances. Packaging complies with regulations for corrosive organic acids, typically in plastic or glass bottles within padded cartons. Transportation is via ground or air, with all required hazard labeling and documentation for safe, compliant delivery.
    Storage 2,2-Dimethylsuccinic acid should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of heat and moisture. It should be kept out of direct sunlight and incompatible substances, such as strong oxidizers. Properly label the storage container, and ensure that appropriate safety measures and personal protective equipment are available when handling the chemical.
    Application of 2,2-Dimethylsuccinic Acid

    Applications of 2,2-Dimethylsuccinic Acid in Industrial Manufacturing

    2,2-Dimethylsuccinic Acid serves as a specialty aliphatic dicarboxylic acid utilized in several advanced industrial segments where precise molecular architecture and controlled reactivity are essential. As the direct manufacturer, we support leading formulation developers and production teams with technical data, compliance insight, and process handling guidelines for high-value downstream transformation.

    1. Fine Chemical Synthesis Intermediate

    2,2-Dimethylsuccinic Acid operates as a selective building block in complex organic synthesis, including the preparation of custom esters, specialty anhydrides, and advanced pharmaceutical intermediates. Chemists benefit from its sterically rich backbone for developing target molecules where branching is key to downstream activity, particularly in regulated fine chemical and drug intermediate sectors.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • US FDA 21 CFR Part 210/211 (Pharmaceutical cGMP)
    • REACH (EC 1907/2006) Registration
    • ISO 9001:2015 (Quality Management Systems)

    Typical usage ratio

    • 5–20 mol% of total substrate mass, adjusted based on target molecule complexity and required yield rate

    Downstream process integration

    • Introduced in the condensation or coupling step, typically after initial precursor formation, often via controlled batch or continuous-flow reactors

    Final product types

    • Custom synthetic intermediates for pharmaceuticals
    • Branched aliphatic esters and anhydrides
    • Performance agrochemical ingredients

    2. Polymeric Additive for Copolyester Manufacturing

    In advanced polymer plants, 2,2-Dimethylsuccinic Acid functions as a diacid comonomer to tune crystallinity, reduce melting temperature, and modify mechanical properties of specialty copolyesters and aliphatic polyamides. Its use allows polymer producers to create materials with targeted flexibility, clarity, and controlled degradation profile for use in engineered plastics and fiber applications.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management Systems)
    • EN 15593:2019 (Packaging–Hygiene Requirements)
    • REACH (EC 1907/2006) compliance for monomer inclusion
    • UL 94 (Flammability of Plastic Materials) where applicable to product

    Typical usage ratio

    • 1–7 wt% of total dicarboxylic acid content in the polycondensation mixture, adjusted based on desired polymer performance

    Downstream process integration

    • Added during the esterification or polycondensation stage, prior to high-vacuum finishing; can be co-fed with other diacids or as a masterbatch

    Final product types

    • Co-polyester resin pellets for film extrusion
    • Modified polyamide fibers for technical textiles
    • Impact-resistant engineered plastic parts

    3. Specialty Plasticizer Component in Wire & Cable Compounds

    Cable compound formulators apply 2,2-Dimethylsuccinic Acid as a plasticizer precursor, using it to synthesize custom dialkyl esters that provide improved flexibility and low-temperature performance in PVC and other polar resins. The resulting formulations help meet demanding electrical insulation and mechanical stress requirements, especially in high-performance and specialty cable segments.

    Industry compliance standards

    • IEC 60811-1-1: Electrical cables—Test methods for non-metallic materials
    • RoHS Directive (2011/65/EU)
    • REACH SVHC (Substance of Very High Concern) listings compliance
    • UL 1581 (Reference Standard for Electrical Wires, Cables, and Flexible Cords)

    Typical usage ratio

    • 2–8 phr (parts per hundred resin) in cable plasticizer blends; actual dosage guided by required flexibility and dielectric strength

    Downstream process integration

    • Undergoes esterification in a dedicated reactor with target alcohol (e.g., isobutanol), yielding the diester plasticizer, which is subsequently blended into PVC compounding prior to extrusion or molding

    Final product types

    • PVC-coated electrical wire and data communication cables
    • Flexible cord insulation jackets
    • Sheathing compounds for automotive and industrial wire harnesses

    4. Chemical Building Block in Biodegradable Solvent Synthesis

    Producers of next-generation green solvents utilize 2,2-Dimethylsuccinic Acid as a reactive precursor for environmentally conscious formulations. Through esterification or amidation, it yields structures that provide controlled volatility, low toxicity and enhanced biodegradability, supporting compliance with international directives on sustainable chemicals for coatings, inks, and cleaning applications.

    Industry compliance standards

    • OECD 301B (Ready Biodegradability Test)
    • US EPA Safer Choice Program enrollment
    • EU Ecolabel Regulation (EC) No 66/2010
    • REACH Annex XVII (restrictions on chemicals in consumer products)

    Typical usage ratio

    • 10–30 mol% of total acid or solvent base feedstock, modulated per targeted evaporation profile and solvency power

    Downstream process integration

    • Incorporated at the solvent precursor synthesis stage, using direct esterification, transamidation, or transesterification processes, typically in jacketed glass or stainless reactors under vacuum

    Final product types

    • Low-VOC solvents for water-based paint and printing ink applications
    • Biodegradable degreasing fluids for electronic assembly and maintenance
    • Green cleaning agents and specialty formulation bases
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    Certification & Compliance
    More Introduction

    Introducing 2,2-Dimethylsuccinic Acid: A Chemist’s Perspective on Quality and Utility

    What Sets 2,2-Dimethylsuccinic Acid Apart in Our Product Line

    Our team has been working with dicarboxylic acids for decades. Through years of refining production methods and keeping a close eye on feedback from industrial partners, we’ve found 2,2-Dimethylsuccinic Acid to occupy a valuable niche thanks to its unique structure and pure, controlled synthesis. Chemical structure isn’t just a matter for the lab bench. Subtle changes in branching, sterics, and molecular symmetry influence performance, safety, and outcomes in every downstream application. The two methyl groups at the 2 position in 2,2-Dimethylsuccinic Acid make a tangible difference—impacting solubility, reactivity, and thermal profile compared to less substituted analogues such as succinic and methylsuccinic acids.

    Our production focuses exclusively on the solid form of 2,2-Dimethylsuccinic Acid. We reach purity levels upwards of 99.0% by using carefully selected raw materials and modern purification steps. This degree of purity doesn’t simply look good on specs sheets; it translates to cleaner reactions, fewer byproducts, and a smoother path for our clients who value precision and repeatability in their downstream syntheses. Anyone who’s faced an inconsistent batch on an industrial scale knows how important it is to have reliable, batch-tested material. This is especially true for those working in fine chemical synthesis, polymer intermediates, or pharmaceutical research.

    Model, Grades, and Packaging: Practical Answers from Daily Experience

    We manufacture 2,2-Dimethylsuccinic Acid under a single model tailored to high-purity requirements. Each batch undergoes multi-stage purification to remove trace organics, moisture, and potential catalysts—a process developed through years of troubleshooting when previous syntheses led to undesired outcomes in customers’ production lines. Our standard material reaches a melting range in line with the literature, maintaining physical consistency that brings peace of mind to R&D labs and pilot plants. Typical shipment sizes start from sealed 1 kg foil pouches for laboratory use and scale up to 25 kg fiber drums for bulk consumption. Every shipment moves with moisture-proof lining, since dicarboxylic acids can pick up ambient moisture during shipping, which can upset stoichiometry and reaction controls for sensitive downstream steps.

    We do not segment this product into multiple technical grades, as our experience suggests that variations among lower-purity grades introduce more complications than cost savings can justify. By focusing on a single, high-performance grade, we can guarantee the absence of problematic residuals and impurities. In applications where trace contaminants can poison catalysts or disrupt analysis, this makes a measurable difference. Real-world users—especially those scaling up to process development—have confirmed that a predictable supply is often more valuable than a marginal price cut from a technical grade. Newcomers to this fine chemical learn this lesson quickly after running into reproducibility roadblocks from less rigorous suppliers.

    Applications: A Practitioner’s View of Utility, Not Just Possibility

    Our 2,2-Dimethylsuccinic Acid serves as a backbone in organic synthesis. Its unique substitution pattern means reactivity is modulated: the two methyl groups introduce steric bulk, reduce the rate of some addition reactions, and prevent undesired side reactions that can occur with other succinic derivatives. This allows chemists to use it in settings where control and selectivity matter as much as conversion yield. In esterification schemes, for instance, the steric hindrance can help limit over-reactions or polymerization, making purification easier for certain resins and specialty polymers. Our customers in agricultural and fine chemical research highlight its reliability in coupling and condensation reactions, as well as in the design of functionalized materials such as crosslinking agents and novel monomers.

    Formulation scientists and synthetic chemists often ask us how 2,2-Dimethylsuccinic Acid stacks up against glutaric, succinic, or methylsuccinic acids. Our firsthand production and customer application data show that the extra methyl branches are more than a structural quirk. They cause a real shift in solubility both in water and common organics, which eases isolation or manipulation at certain stages of multi-step procedures. In polyester and polyamide synthesis, for example, its performance differs from unbranched dicarboxylic acids by creating polymers with altered flexibility, glass transition temperatures, and resistance to hydrolysis. This sort of structure-property relationship is vital for R&D teams, who report that access to consistent, branched building blocks opens new space for functional materials development. We see similar impacts in pharmaceutical research, where the compound’s controlled hydrolysis behavior can broaden its application as a linker or protecting group precursor.

    In electrochemical and specialty battery research, our observations show that dicarboxylic acids with branched structures sometimes help stabilize electrode materials or fine-tune ionic transport pathways. These sectors remain in flux, with many scientists exploring the unique performance edge that comes from using molecularly precise intermediates.

    Key Differences: Insights Gained from Production and End-Use Feedback

    Every batch of 2,2-Dimethylsuccinic Acid embodies choices made at the reactor, the filtration column, and the warehouse. Through conversations with customers and our own tests, it’s clear that not all dicarboxylic acids behave equally. Compared with succinic acid, our product resists rapid dehydration and decarboxylation. This lengthens its usable temperature window, especially valuable during large-scale esterifications where temperature spikes can occur. It’s also more robust toward oxidative degradation, so product shelf life holds up well—lessening worry over degradation between delivery and lab work.

    Rarely do substitutes match this performance without trade-offs. Adipic and glutaric acids, though popular, lack the steric shielding of the two methyls at the 2 position. This subtle molecular difference influences not only reactivity but safety: 2,2-Dimethylsuccinic Acid produces fewer volatile byproducts under thermal or acidic stress, helping with air quality in the workplace and improving yield consistency in closed system reactors. Over the years, manufacturing partners have reported fewer filter blockages and less polymer fouling with our product, which translates to smoother downstream operations.

    Some buyers look for alternatives believing succinic acid’s lower price may suffice. In pilot plant trials and feedback from regular users, we’ve seen that process scientists often return to 2,2-Dimethylsuccinic Acid after struggling with inconsistent product quality, unexpected side reactions, or poor reproducibility with plain succinic acid. That peace of mind is hard to price. For projects depending on robust, clean-running chemistry, 2,2-Dimethylsuccinic Acid isn’t just a ‘substitute’—it’s a purpose-built tool.

    Manufacturing Process: Knowledge Earned in the Reactor

    Our team oversees each stage of synthesis from select raw materials to isolation. Organic chemists know dicarboxylic acids are not forgiving: trace transition metals or incomplete neutralization can haunt a product, showing up later in test results or downstream reactivity. Through years of process iterations, we’ve switched from old batch-wise approaches to more controlled, continuous-flow systems, which help nail down tight specifications and improve solvent recovery.

    Each batch undergoes sequential recrystallization and drying. Hands-on QA staff sample every lot for melting point, IR fingerprint, and residual solvents—issues we identified early on as common culprits for off-spec reactions in polymers and pharmaceutical intermediates. By building these touchpoints into daily manufacturing practice, we have reduced customer complaints and improved long-term partnerships.

    In previous decades, we fielded customer calls about color change and trace impurity buildup. We traced these problems to inconsistent oxidant quality and incomplete downstream rinses; changes in supply chain management and on-site analytic capacity have since helped us correct this for good. These lessons, learned over hundreds of batches, are why we can commit to pure, uncontaminated 2,2-Dimethylsuccinic Acid at scale today.

    Sustainability and Safety: Practical Responsibility, Not Just Rhetoric

    Over the last decade, expectations around chemical manufacturing sustainability have grown. For us, commitments begin with waste minimization, routine audit trails, and raw material sourcing from reputable partners. Our process generates manageable byproducts, and most effluent streams are recycled or treated on-site—the direct result of close collaboration between process engineers and environmental staff. Out in the field, our clients working in formulation appreciate that our product’s naturally high purity lowers the need for extra purification steps, thereby reducing solvent usage and waste downstream.

    Safe handling comes from product stability and packaging integrity. We ship our 2,2-Dimethylsuccinic Acid in moisture-resistant containers, clearly labeled for both transportation safety and stockroom efficiency. Storage conditions—cool, dry, and sealed—keep the acid free from ambient contaminants and atmospheric water. Field reports over the past few years confirm that our product resists caking and discoloration long after delivery, provided customers maintain proper storage. This reliability protects workers, scales up well in production, and keeps usability high for months after opening.

    We keep a regular schedule of hazard assessments on our plant floor and conduct annual retraining for our logistics team. In the rare event of a spill, standard dicarboxylic acid protocols suffice. Over the years, feedback loops with our logistics partners have reduced workplace incidents and improved overall product stewardship.

    Challenges We Face and Solutions Developed from Daily Manufacturing

    No manufacturing process avoids all problems. Seasonal humidity and temperature swings challenge the consistency of non-anhydrous acids, especially for solid, crystalline materials. Our solution has relied on both well-sealed packaging and facility upgrades—storage areas include humidity controls, and QA regularly tests for moisture content each quarter. If a batch ever shows higher-than-expected water uptake, we reroute it for on-site re-processing instead of passing problems onto clients.

    Supply chain disruptions, especially around precursor chemicals, occasionally put pressure on lead times. Over several years, we have worked out alternate supply agreements and maintain safety stocks. This means we can keep buffers through turbulent seasons, so customers seldom face result delays. Our raw materials come from verified sources, and every new batch runs through incoming inspection as well as end-product analysis. Customers who rely on consistent source verification have noted fewer project delays as a direct result of these efforts.

    Analytical complexity is another issue. Characterising exact branching, purity, and trace-level impurities of a dicarboxylic acid isn’t trivial. We’ve built up in-house capabilities for high-resolution NMR, LC-MS, and gas chromatography. These investments grew out of specific customer requests to explain subtle IR peaks or uncertain melting profiles—and they now allow us to guarantee new levels of transparency for those who need to trace every contaminant in pharmaceutical or polymer-grade materials. Having this data available isn’t simply an academic concern; it builds trust with regulatory compliance teams and industrial end-users alike.

    Continuous Improvement: Trust Built Through Chemical Know-How

    Operational excellence comes from evaluating complaints, learning from process inefficiencies, and being open to direct conversations with end users. In earlier years, customers initiated requests for specialized particle sizes or re-packaging. We responded by rolling out secondary screening and additional sizing steps—now delivered as custom orders for those who require consistent flow in automated equipment. Packing partners who needed non-standard quantities now receive custom batch sizes, speeding up their own workflows and trimming waste from repeated re-packaging on their end.

    Some customers reached out seeking help differentiating our acid from competitor products. We ran side-by-side application trials with comparative blends and provided detailed reactivity profiles, especially for those integrating new acids into established synthetic routes. These joint projects not only solidified partnerships but led us to refine both our in-process control points and final analytic reporting, benefitting all customers. On several occasions, these partnerships even guided minor formula tweaks, resulting in improved shelf stability or solubility for specific client applications.

    Through routine check-ins with process engineers, R&D scientists, and supply chain managers, we gather data and stories that feed back into production. As impurities, storage changes, or new technical requirements arise, our willingness to adapt ensures the stability and long-term relationships our customers count on.

    A Closer Look at Industry Use-Cases and End-Product Success Stories

    Not all chemical intermediates get star billing, but the right choice at this stage determines success several steps downstream. In polymer design, we witnessed a customer’s breakthrough in flexible copolyesters attributed directly to the unique insertion of our 2,2-Dimethylsuccinic Acid. The resulting materials withstood harsher hydrolytic conditions and maintained elasticity where similar chains with unbranched acids failed. Across several pilot plants, those pursuing targeted modifications of polyamides and adhesives found the controlled reactivity and lower volatility of our product improved their overall process reliability, cutting cleaning downtime and facilitating higher throughput.

    Another customer in agricultural chemistry attributed enhanced product stability and shelf life to the adoption of our acid, replacing more reactive, less predictable alternatives which often resulted in regulatory headaches and product recalls. The structured, predictable chemical behavior of 2,2-Dimethylsuccinic Acid gave them a competitive advantage, reducing reformulation costs and improving time-to-market for their innovations.

    Pharmaceutical research, while often focused elsewhere, has found our dicarboxylic acid’s chemical compatibility and stability invaluable for linker chemistry, protecting group applications, and intermediate building blocks. We field regular requests for detailed impurity profiles and gladly provide the analytical data needed for regulatory files. For formulation teams, the predictable storage profile and batch consistency simplify risk assessments and streamline validation requirements.

    Custom-synthesis partners and toll manufacturers appreciate that our regular order flow and transparency make it easier to manage tight production timelines. They count on us to deliver without last-minute surprises, and we know this reliability shapes their own reputations with end clients. By focusing on consistency and openness, everyone in the chain benefits.

    Path Forward: Strengthening the Role of 2,2-Dimethylsuccinic Acid through Ongoing Collaboration

    From the viewpoint of daily manufacturing, 2,2-Dimethylsuccinic Acid stands out not simply as an alternative in the dicarboxylic acid category, but as a deliberately engineered tool that improves reliability, safety, and application range for industries that value control and precision. As demand shifts with new material science, pharmaceuticals, and specialty chemical development, we keep our doors open to feedback, special requests, and joint problem-solving.

    Our process of continuous feedback, adaptation, and transparency shapes the product as much as any batch reactor ever did. By welcoming input from chemists, engineers, and procurement teams, we can keep fine-tuning our manufacturing and shipping practices, adding real value to clients who seek a dependable source of high-purity 2,2-Dimethylsuccinic Acid. This ongoing dialogue not only helps us deliver consistent, reliable product—it helps keep our team accountable to the highest standards of safety, efficiency, and scientific integrity.

    Industry growth depends on shared expertise, reliable partnerships, and a willingness to innovate at every stage of production. We remain proud to support our partners with chemical tools like 2,2-Dimethylsuccinic Acid—analytically sound, thoroughly tested, and refined through years of daily, real-world use. Our aim is to aid those who strive for breakthrough performance and quality, knowing that small molecular differences shape large-scale outcomes across the chemical industry. Through pragmatic manufacturing and open collaboration, the impact of our work reaches well beyond our own plant floor.