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2,2-Dichloropropane

    • Product Name 2,2-Dichloropropane
    • Alias Propylene dichloride
    • Einecs 211-752-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    189986

    Cas Number 594-20-7
    Molecular Formula C3H6Cl2
    Molecular Weight 112.99 g/mol
    Appearance Colorless liquid
    Odor Ether-like odor
    Melting Point -80 °C
    Boiling Point 96-97 °C
    Density 1.171 g/cm³ at 20 °C
    Solubility In Water Insoluble
    Flash Point 17 °C (closed cup)
    Vapor Pressure 63 mmHg at 25 °C
    Refractive Index 1.437 at 20 °C

    As an accredited 2,2-Dichloropropane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle labeled "2,2-Dichloropropane," tightly sealed, with hazard symbols and chemical identification clearly displayed.
    Shipping 2,2-Dichloropropane is shipped as a hazardous chemical, typically in secure, clearly labeled containers compliant with international regulations. Transport must ensure protection from heat, ignition sources, and rough handling. Proper documentation, including Safety Data Sheets (SDS), must accompany the shipment, and only authorized carriers trained in handling hazardous materials should be used.
    Storage 2,2-Dichloropropane should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames. Keep it separate from oxidizing agents and strong bases. Avoid direct sunlight and sources of ignition. Proper labeling and secondary containment are recommended to prevent leaks or spills. Store in accordance with local regulations.
    Application of 2,2-Dichloropropane

    Applications of 2,2-Dichloropropane in Industrial Manufacturing

    As a specialized producer of 2,2-Dichloropropane, we supply this raw material to a focused range of industrial formulations and processes where its unique chemical properties directly address defined technical requirements. The following sections highlight key application scenarios where it plays an irreplaceable part in downstream manufacturing, with industry-specific compliance and process details.

    1. Intermediate in Agrochemical Synthesis

    Agrochemical and crop protection manufacturing plants utilize 2,2-Dichloropropane as a chlorinated intermediate for the synthesis of selective herbicides and soil fumigants. Reactivity and halogen placement are critical for producing downstream actives, especially in post-emergent herbicide production lines that require precise control of molecular substitution patterns. Process chemists incorporate it for halogen exchange or carbon chain extension reactions, supporting high-volume campaigns for seasonal demand windows.

    Industry compliance standards

    • ISO 9001:2015 Certified Quality Management Systems
    • REACH Regulation (EC No 1907/2006) registration for chemical intermediates
    • OECD Guidelines for the Testing of Chemicals (applicable to agrochemical actives)
    • National-level pesticide registration regulations (EPA, EU Plant Protection Products Regulation EC 1107/2009)

    Typical usage ratio

    • 5–15% (w/w) as a reactive intermediate; optimized to target reaction yield and molecular conversion efficiency

    Downstream process integration

    • Introduced at the alkylation or halogenation stage in multi-step batch or semi-continuous synthesis of herbicide actives such as chlorinated alanine derivatives

    Final product types

    • Formulated selective herbicides (emulsions, water-dispersible granules)
    • Soil fumigant concentrates

    2. Solvent and Reaction Medium in Pharmaceutical Intermediate Manufacture

    Process development groups in the pharmaceutical sector incorporate 2,2-Dichloropropane as a solvent or co-solvent in the preparation of small-molecule intermediates, specifically when alternative solvents present reactivity or extraction challenges. Its low water miscibility and stable chlorinated backbone enable efficient extraction or crystallization steps for halogenated intermediates within regulated cGMP chemical plants, particularly during scale-up and routine API intermediate production.

    Industry compliance standards

    • Good Manufacturing Practice (GMP) guidelines for active pharmaceutical ingredient (API) production – ICH Q7
    • Ph. Eur. 2.4.24 (solvent trace analysis requirements)
    • FDA 21 CFR Part 211 for finished pharmaceutical intermediates
    • Chemical safety assessed under the European Medicines Agency (EMA) guidelines

    Typical usage ratio

    • 10–30% v/v as process medium; adjusted according to substrate solubility and crystallization endpoint specificity

    Downstream process integration

    • Charged as part of the solvent system during condensation or substitution reactions, and removed during phase-separation or purification of halogenated intermediates

    Final product types

    • Halogenated pharmaceutical intermediates for cardiovascular or antimicrobial APIs
    • Fine chemicals for medicinal chemistry pipelines

    3. Chain Transfer Agent in Polymer Manufacturing

    2,2-Dichloropropane provides consistent molecular weight regulation in controlled radical polymerizations, supporting downstream plants that manufacture specialty polymers for coatings and impact-resistant plastics. Industrial chemists include it as a chain transfer agent to ensure tight polydispersity while tuning the physical properties in continuous or batch polymerization reactors—especially where softer processing windows are crucial for thermoplastic resin output.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management in polymer plants
    • REACH registered for use in polymer synthesis (monomer and CTA categories)
    • ASTM D256 (testing of plastics for impact resistance)
    • UL 94 Flammability Rating Guidance for plastics

    Typical usage ratio

    • 0.05–0.5 wt%, scaled up or down in proportion to monomer loading and desired chain length

    Downstream process integration

    • Metered directly to the polymerization reactor during the initial charging phase in emulsion or solution polymerizations

    Final product types

    • Specialty thermoplastic resins for precision-molded parts
    • Acrylic-based impact modifiers for automotive and appliance applications

    4. Extraction Solvent for Specialty Chemical Purification

    In downstream plants producing valuable halogenated fine chemicals or extracting target compounds from complex reaction mixtures, 2,2-Dichloropropane serves as a selective extraction solvent. Process engineers exploit its immiscibility profile for liquid-liquid separation, particularly when isolating chlorinated or lipophilic compounds in multi-stage purification setups designed to maximize throughput and reduce downstream impurity carryover.

    Industry compliance standards

    • ISO 9001:2015 Certified Process Control
    • Responsible Care® Security Code for site management and solvent control
    • Compliance with Globally Harmonized System (GHS) for safe handling
    • Local emissions and waste solvent disposal permits (e.g., European IPPC Directive 2010/75/EU)

    Typical usage ratio

    • Volume ratio of 0.5:1 to 1.5:1 in phase-separation steps, determined by partition coefficient and compound solubility curves

    Downstream process integration

    • Added to reaction broth or crude mixture for selective extraction; followed by phase separation, washing, and recovery under reduced pressure

    Final product types

    • Highly purified halogenated fine chemicals
    • Industrial precursors for fragrance and flavor intermediates
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    Certification & Compliance
    More Introduction

    Understanding the Value of 2,2-Dichloropropane from the Manufacturer’s Bench

    We have watched 2,2-dichloropropane evolve from a niche compound into a tool that underpins modern chemical processes. This material, known by its CAS number 594-20-7, brings utility in both specialty synthesis and industrial applications. Our facility that produces 2,2-dichloropropane works closely with end users across a spectrum of sectors—from organic synthesis and research to manufacturing. Let’s dive into the unique properties of this compound and unpack what truly sets it apart from others on the chemical market.

    Defining 2,2-Dichloropropane

    2,2-dichloropropane bears the molecular formula C3H6Cl2. At room temperature, it forms a colorless and flammable liquid with a characteristic, somewhat sweet odor. Its boiling point sits near 96°C, and it offers a density close to 1.13 g/cm³. Working with this material, we routinely focus on protecting purity through multi-stage distillation and incorporating quality controls, knowing even minor feedstock variations can change the compound’s downstream behavior. The small molecule nature and dual chlorination open pathways for a range of transformations that single-chlorinated or larger molecules can’t support.

    Role of 2,2-Dichloropropane in Industry

    We see the biggest draw of 2,2-dichloropropane among customers who operate reactors tuned for halogen exchange, alkylation, or selective dehydrohalogenation. Lab-scale chemists and scale-up engineers appreciate its directness in delivering chlorine where you want it, and nowhere else. The two chlorine atoms on the same carbon set up a springboard for nucleophilic substitutions that would stall if a different dichloroalkane showed up. In practice, this allows for functionalization steps or cleaner elimination reactions that add value to pharmaceuticals, agrochemicals, and fine chemicals.

    In our own experience, solvent use comes next in both popularity and volume. 2,2-dichloropropane dissolves a variety of organic substrates, making it a choice for extraction, reaction medium, and sometimes for cleaning. The halogen presence hardens the molecule against attack under routine conditions, extending the shelf life of finished products dissolved in it. Some customers in the electronics and specialty coatings sectors use it to manage polymer residues or stubborn oligomers. We support these activities by ensuring the material’s low water content and stability throughout the supply chain.

    Technical Specifics from Inside the Plant

    Watching each production batch flow through the columns, we make constant adjustments to secure specifications required by our customers. Chlorinated hydrocarbons of similar size—such as 1,2-dichloropropane or 1,1-dichloropropane—share some features, but these isomers diverge in how they react or hold up against bases, acids, and heat. We see that many of our buyers request assay levels of over 99% for 2,2-dichloropropane, with moisture measured down to the tens of ppm. Trace impurities like monochloropropane or trichloropropanes matter for oxidation and substitution patterns. So, we rely on a combination of gas chromatography and IR spectroscopy, tightened up by years of operator know-how, to confirm the right product leaves our warehouse doors.

    The physical profile makes storage and handling straightforward for most facility teams. It stores in standard drums or IBCs, under nitrogen blanketing for large volumes. With proper ventilation, spills evaporate quickly, but we always stress the need for personnel training in safe handling to prevent fire risk or vapor inhalation. We've worked with customers revising protocols during plant expansions and always recommend localized vapor monitors and solvent-resistant PPE wherever large-scale use occurs.

    Comparing 2,2-Dichloropropane with Related Products

    The world of chlorinated propanes covers several isomers, each showing unique quirks. 1,2-dichloropropane might get more press thanks to its role as a solvent and precursor for perchloroethylene and propylene oxide. In our manufacturing runs, we see distinct markets: 1,2-dichloropropane handles bulk commodity tasks, while 2,2-dichloropropane stays in demand for designer transformations needing sharper regioselectivity. The latter is less likely to produce unwanted rearrangements or side products due to its symmetrical chlorination.

    Working with this molecule side by side with its isomers, we notice the vivid contrasts in reactivity. 2,2-dichloropropane’s two chlorines bracket the central carbon atom—this C-2 position stands out in nucleophilic substitution. For alkylation efforts, one often observes fewer byproducts than with 1,1-dichloropropane. 1,2-dichloropropane often leads to more scrambling or elimination under hard reaction conditions. For us, the main practical difference has always been reliability in synthetic conversions, which means fewer headaches downstream and higher yields.

    Purity, Safety, and Quality: Lessons from the Manufacturer’s Floor

    Few things waste resources faster than a contaminated batch. In our experience, off-spec material leads to unintended consequences—from reaction interruptions on customer lines to occupational safety calls. Strict purity control has become one of our calling cards. Using real-time sensors and automation tools, we keep a constant grip on composition. Chlorinated hydrocarbons demand respect: lower grade batches sometimes trigger corrosion issues, by-product formation, or exposure to traces of genotoxic compounds. As the producer, we place health and safety above all, with closed transfer, vapor scrubbing, and up-to-date emergency drills as standard practice.

    Raw material quality influences every drum shipped. Where possible, we contract directly with upstream feedstock providers and invest in regular plant audits. Every operator in our facility gets training not only in the chemistry but in the regulatory requirements mapped out by local and global authorities. We view this as more than a compliance measure; it’s about protecting both our team and our customers. When a customer calls about an out-of-spec drum, we have the tools and expertise to isolate the batch, trace upstream causes, and rapidly replace the order. It’s a feedback loop that runs on reliability, not luck.

    Regulation and Environmental Considerations

    Regulators look closely at chlorinated solvents and intermediates, including 2,2-dichloropropane. We live through each updated directive firsthand, balancing operational efficiency with emissions control, safe disposal, and recycling measures. Our plant has moved towards closed-loop systems for waste minimization. Offgassing and volatilization not only mean lost product but carry risk for staff and the environment. In practice, we invest in carbon filtration and scrubbing towers, so vented air meets modern safety limits before it leaves our site.

    We have witnessed a steady uptick in requests for greener processes, both from customers and the wider supply chain. Halogenated organics attract added scrutiny in ESG audits and downstream certifications. We keep detailed logs of solvent recovery, process water management, and downstream fate of all waste streams. Several of our larger customers want certificates tracking every supply chain step; we cooperate gladly, knowing that transparency builds trust for everyone involved.

    Supply, Demand, and Market Trends

    In the early years, most orders for 2,2-dichloropropane stayed local, filling gaps in domestic chemical manufacturing. Over time, demand shifted. A growing number of customers in Asia and North America now come to us both for bulk and small-lot orders. As more fine chemical sectors tune their manufacturing lines, the need for reliable, high-purity chlorinated intermediates has only increased. Supply disruptions, whether from feedstock price swings or regulatory changes, ripple quickly through the system. We keep buffer inventories and long-term contracts to manage these shifts with minimal surprise for our customers.

    One market challenge remains unpredictability in global shipping and chemical logistics. We have seen port closures and regulatory slowdowns lengthen lead times for raw materials and finished goods alike. Our strategy keeps multiple approved routes and trusted freight partners, meaning most orders ship on schedule. We believe open client communication can smooth even the roughest supply bumps—customers see real value when they don’t get caught off-guard by sudden delays.

    R&D: Improving 2,2-Dichloropropane for Modern Applications

    Continual investment in research and development shapes how we make and deliver 2,2-dichloropropane. Over the past decade, we have refined distillation technology and product stabilization techniques. Where stabilizers were once essential to keep batches from yellowing or decomposing, improvements in process purity now let us ship cleaner, nearly additive-free product. This suits customers aiming for ultra-clean end uses, like electronics, that can’t risk impurities at the ppm level.

    Our technical staff often partners with application chemists on customer R&D teams to adapt batches for special reactions or to troubleshoot problems. In one case, a customer working on a novel heterocycle synthesis hit a snag due to trace acetal impurities—joint investigations on both sides pinpointed a minor process tweak, restoring yields and eliminating regulatory risk. These shared efforts help keep 2,2-dichloropropane a textbook example of the cross-pollination between producer and end user that drives advancement.

    Safety in Use and Handling, From Drum to Reactor

    Manufacturing and handling chlorinated solvents require more than good chemistry; they demand attention to every step in use. Our experience supplying to different sectors highlights varied risk profiles. For process-scale users, the main risks lie in static buildup during transfer or holding tanks, with vapor controls being absolutely necessary. For smaller labs, inhalation and skin contact cause the most concern—an extra layer of awareness pays off.

    We advocate for site-specific hazard assessments before a new project launches. In customer audits, we’ve seen everything from inadequate spill kits to poorly maintained ventilation—as a manufacturer, we see it as our job to flag these gaps and share best practices. It doesn’t take much for a minor oversight to snowball into a logistic or health challenge. Frequent turnover means new training material lands on desks as soon as standards change, reflecting the most current interpretation of safe handling for chlorinated hydrocarbons.

    Supporting Downstream Value Creation

    The backbone of good chemical manufacturing lies in empowering others’ innovation. 2,2-dichloropropane might not grab headlines, yet it supports the backbone of progress by enabling transformations otherwise out of reach. Customers tell us that this compound allows more precise control during alkylation or halogen-exchange reactions. We assemble every batch with this feedback in mind, understanding that repeatability and reinforcement of positive user experiences carry as much weight as any technical spec.

    The fine and specialty chemical industries never stop evolving. New routes for old products, changing regulatory landscapes, unexpected customer use cases—our plant sees it all. It’s our job to make sure the 2,2-dichloropropane we supply fits these shifting demands in real time. Through direct feedback, occasional site visits, and detailed application support, we keep our finger on the pulse, adapting to the market, not the other way around.

    Why 2,2-Dichloropropane Remains a Unique Solution

    With over a decade on our production lines, we have learned what makes 2,2-dichloropropane unique. Its reactivity profile stands apart from its isomers, delivering value through stability and selectivity. Customers return because the product does what it promises, batch after batch—with fewer issues downstream and predictable results. This reliability doesn’t happen by accident; every step, from material sourcing to post-sale support, reflects lessons picked up on the floor.

    For researchers and plant managers facing complex synthetic challenges, 2,2-dichloropropane brings more than a simple reagent. Its adoption signals a commitment to precision chemistry and trust in a supply chain that values transparency and performance. This trust is the real product we provide, alongside every drum shipped. As chlorinated intermediates remain under scrutiny for safety and sustainability, responsible manufacturing and open technical support carry the industry forward, one well-made batch at a time.