Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2,2',6,6'-Tetramethyl-4,4'-Biphenol

    • Product Name 2,2',6,6'-Tetramethyl-4,4'-Biphenol
    • Alias TMBP
    • Einecs 231-222-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    534209

    Cas Number 2437-46-1
    Molecular Formula C16H20O2
    Molecular Weight 244.33 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 219-223 °C
    Boiling Point 428.7 °C at 760 mmHg
    Solubility In Water Insoluble
    Density 1.17 g/cm3
    Purity Typically ≥98%
    Synonyms TMBP, 4,4'-Biphenol, 2,2',6,6'-tetramethyl
    Refractive Index 1.600 (estimated)
    Smiles CC1=CC(=C(C=C1O)C)C2=CC(=C(C=C2O)C)C

    As an accredited 2,2',6,6'-Tetramethyl-4,4'-Biphenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 25g amber glass bottle with a secure screw cap, labeled "2,2',6,6'-Tetramethyl-4,4'-Biphenol" and hazard information.
    Shipping 2,2',6,6'-Tetramethyl-4,4'-Biphenol is shipped in tightly sealed containers, protected from moisture and light. Packages comply with chemical safety regulations, including appropriate labeling and documentation. The product is typically transported via ground or air as a non-hazardous solid, following standard protocols for handling and storage to prevent contamination or degradation during transit.
    Storage 2,2',6,6'-Tetramethyl-4,4'-Biphenol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of moisture and incompatible substances such as strong oxidizers. Protect from light and excessive heat. Ensure proper labeling and keep away from food and drink. Follow standard laboratory chemical storage protocols for safe handling.
    Application of 2,2',6,6'-Tetramethyl-4,4'-Biphenol

    Applications of 2,2',6,6'-Tetramethyl-4,4'-Biphenol in Industrial Manufacturing

    We supply high-purity 2,2',6,6'-Tetramethyl-4,4'-Biphenol directly manufactured at scale for advanced polymer synthesis, specialty coatings, and related applications. Below, we detail core industrial scenarios where this raw material delivers decisive functional and processing benefits within regulated, high-value manufacturing environments.

    1. Polycarbonate Resin Production for Electronic Components

    Producers of high-performance polycarbonate resins select 2,2',6,6'-Tetramethyl-4,4'-Biphenol as a diol monomer for synthesis of resins with elevated thermal stability, low color generation, and enhanced resistance to hydrolysis. This specialty biphenolic structure enables process engineers to target resin properties required by precision electrical and electronic component manufacturers for demanding environments—such as LED reflectors, relay cases, microprocessor sockets, and sensor housings—while supporting efficient melt polymerization on continuous lines.

    Industry compliance standards

    • UL 94 Flammability (V-0, V-2 ratings)
    • IEC 60335 material standards for electrical applications
    • RoHS Directive 2011/65/EU requirements
    • REACH Regulation EC No. 1907/2006

    Typical usage ratio

    • Used at 20% to 40% molar inclusion as the bisphenol component. Exact ratio adjusted for molecular weight targeting and heat distortion specification of the finished resin.

    Downstream process integration

    • Charged into polycarbonate synthesis reactors during phosgenation or transesterification stages; combined with carbonate source to control backbone structure and thermal properties.

    Final product types

    • Non-brominated flame-retardant polycarbonate chips for electrical and electronic part molding
    • Optically stable LED housings
    • Relay bases and coil formers
    • Precision molded structural electronic frames

    2. Epoxy Resin System Formulation for High-Temperature Printed Circuit Boards

    PCB laminate producers and advanced composite formulators employ this biphenol in the diglycidyl ether form as a reactive modifier in epoxy systems engineered for thermal stability, low ion migration, and dimensional stability. The methyl-shielded phenolic positions reduce undesired crosslinking and discoloration, enabling consistent performance in multilayer boards required for telecommunications, industrial automation, and aerospace signal routing.

    Industry compliance standards

    • IPC-4101/126 and /129 for high-performance laminates and prepregs
    • IEC 61249 for base materials used in PCBs
    • JIS C 6481:2010 for glass-epoxy substrates
    • RoHS compliance per EN 50581

    Typical usage ratio

    • Added at 8% to 18% by weight of total resin solids; ratio refined based on Tg target and thermal cycling endurance of the end laminate.

    Downstream process integration

    • Integrated during initial blending with liquid diglycidyl ether of bisphenol A (DGEBA) matrix. Subsequent lamination and B-stage curing form stable crosslinked networks for copper cladding and etching.

    Final product types

    • High Tg FR-4 laminates for multilayer circuit boards
    • Metal core printed circuit boards (MCPCB)
    • Halogen-free low-loss electronic laminate substrates
    • Electrical insulation sheets and rigid flex assemblies

    3. Production of Polyarylate and Specialty Transparent Engineering Plastics

    Producers of polyarylate resins utilize 2,2',6,6'-Tetramethyl-4,4'-Biphenol for copolymerization with aromatic dicarboxylic acids, resulting in advanced polymers with excellent clarity, UV stability, and dimensional accuracy at elevated temperatures. Such resins support formation of lightweight, impact-resistant materials used in critical optical and mechanical parts where transparency and resistance to weathering are key selling points, including light guide panels, display enclosures, and high-durability lenses.

    Industry compliance standards

    • FDA 21 CFR 177.1595 for polyarylates in food contact articles (where applicable)
    • ISO 4892-2 for light and weathering resistance
    • EN 60068 environmental test standards
    • RoHS and REACH (lead and phthalate-free requirements for consumer goods)

    Typical usage ratio

    • Used from 25% to 50% molar in diol component feed, balanced according to the melt viscosity and required glass transition point of the finished plastic.

    Downstream process integration

    • Enters directly into the ester exchange or melt polycondensation stage with aromatic dicarboxylic acids such as terephthalic or isophthalic acid, preceding pelletization and extrusion.

    Final product types

    • Transparent optical sheets and films
    • Protective cover plates and instrument panel windows
    • High-strength lighting diffusers
    • Precision-molded optical device bodies

    4. Synthesis of Advanced Polyethersulfone (PES) Membranes for Filtration Applications

    Manufacturers of high-specification membranes apply this biphenol as a monomer for polyethersulfone synthesis, targeting membrane sheets and fiber modules with excellent oxidative stability, ion resistance, and controlled porosity for use in water treatment, pharmaceutical, and food processing. Its bulk methylation and rigid backbone enable process engineers to tune porosity and mechanical strength at the wet-phase inversion stage, allowing reproducible performance in the most demanding filtration operations.

    Industry compliance standards

    • USP Class VI and ISO 10993-1 for medical device materials (for medical and bioprocess use)
    • FDA 21 CFR 177.2440 for polysulfone resins used in food contact
    • NSF/ANSI 61 for potable water system components
    • EN 285:2015 for sterilizable devices

    Typical usage ratio

    • Incorporated at 10% to 40% molar ratio in biphenol component feeds, with adjustment according to porosity and flux specifications for hollow fiber versus flat sheet formats.

    Downstream process integration

    • Monomer incorporated during polymerization with dichlorodiphenylsulfone in polar aprotic solvents; cast into films or fiber dope solutions before solvent exchange-induced phase separation and post-treatment.

    Final product types

    • Ultrafiltration and nanofiltration membranes
    • Sterile filtration modules for bioprocessing
    • Reverse osmosis pretreatment cartridges
    • Food-grade water purification meshes and hollow fibers

    5. Specialty Coatings for High-Reliability Transparent Protective Layers

    Industrial coating formulators adopt the biphenol as a core diol in crosslinkable resin resins for scratch-resistant, UV-stable, and high-clarity protective coatings. These coatings are applied to optical lenses, display filters, and specialty glass via dip-coating, flow coating, or spin coating methods. Due to its steric hindrance, the biphenol unit suppresses unwanted coloration and enables high crosslink density for long-lived, abrasion-resistant end products.

    Industry compliance standards

    • ISO 9211 for optical coating durability
    • EN 166 for personal eye protection coatings
    • ISO 2409 for cross-cut adhesion in transparent coatings
    • RoHS and REACH for consumer product safety

    Typical usage ratio

    • Diol dosing at 10% to 35% by mass in resin prepolymer batches; ratio tuned by desired crosslink density, layer thickness, and curing rate.

    Downstream process integration

    • Incorporated in resin feed ahead of isocyanate or melamine curing agents; formulated coating applied by controlled deposition and subjected to thermal or UV curing for surface solidification and property development.

    Final product types

    • Anti-scratch coating for spectacle lenses
    • UV-resistant protective films for touch panels and instrument displays
    • Hard-coat layers for safety visor substrates
    • Clear coatings for architectural glazing
    Free Quote

    Competitive 2,2',6,6'-Tetramethyl-4,4'-Biphenol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing Our Expertise in 2,2',6,6'-Tetramethyl-4,4'-Biphenol

    Decades of Experience and Customer-Centered Development

    Working day in and day out in chemical synthesis, our team knows each compound tells a story, and 2,2',6,6'-Tetramethyl-4,4'-Biphenol — sometimes abbreviated as TMBP — stands out for good reason. With over two decades in production, we've tailored our process to meet the evolving needs of resin manufacturers, materials scientists, and specialty polymer researchers. Our plant’s familiarity with the stringent demands of end applications often shapes how we test, filter, and grade each batch.

    Chemists regularly rely on this molecule as a core building block for high-performance polymers, especially in the electronics, aerospace, and environmental segments. Our staff understands the impact that minor impurities make down the line, so our operational focus always circles back to purity and consistency. It doesn’t matter if the client’s application involves printed circuit board materials or advanced engineering films — the upstream foundation sets the tone for every step that follows.

    Core Specifications and the Spirit of Improvement

    We manufacture 2,2',6,6'-Tetramethyl-4,4'-Biphenol with attention to purity, color, and thermal stability. Over the years, customer feedback has prompted tighter color standards (APHA < 60), and HPLC verification as an anchor for purity control. Moisture content consistently stays under 0.1%, an absolute must to avoid downstream processing headaches, especially when customers use it in polycarbonate or epoxy resin synthesis.

    Particle size distribution can hold back a production run, so we pay close attention to milling and sieving. Most clients specify particle diameters between 20 and 80 mesh, and our equipment is calibrated every morning, tracked with process logs visible right on the plant floor. It’s no exaggeration to say every operator in our facility knows that a clump or contaminant can cause equipment shutdowns at a customer’s compounding plant. We’d rather invest in extra screening, than let a single batch slip.

    By adjusting reaction conditions, we’ve trimmed residual methylphenol and related byproducts into single-digit ppm ranges. Each operator here knows how long it took to optimize these steps — not only to pass standard QC, but to raise downstream yields for the formulators who trust us. Our entire production loop is aligned to guarantee the best possible reproducibility for high-value end products.

    Practical Usage in Real-World Applications

    Walk through any advanced plastics R&D lab, and you’ll see that TMBP runs as a preferred monomer for specialty polycarbonates and polyarylates. In copolymeric blends, it offers enhanced thermal resistance and hydrolytic stability. We’ve listened closely to feedback from customers in automotive headlamp housings, who pointed out that our high-purity TMBP helps prevent degradation and discoloration, especially in UV-exposed environments. Our chemists aren’t shy about reviewing the mechanics: it’s the bulky methyl groups clustered around the phenolic core that prevent unwanted oxidation or side-reactions, prolonging part lifespans.

    Formulators for LED encapsulants and display backplane substrates value its low color and clean melt rheology during high-temperature molding. Early on, we received shipment rejections from film manufacturers when tiny yellowing appeared; after hands-on trials with their engineers — and by investing in finer colorimetry and packing improvements — rejection rates dropped to nearly zero. Long hours by our QA team paid off in trust, and we remember these lessons every time we scale a new batch. Chemical building blocks like ours often vanish into resin matrices, but a consistent raw input makes all the difference on the production line.

    Epoxy resin manufacturers tell us that even subtle shifts in off-odor or trace inorganic content can throw off entire batches. That’s why our material is regularly filtered through multiple activated carbon beds, and processed with deionized water to keep ionic content low. We keep downstream processing needs in mind, whether customers are aiming for toughened laminates, electrical insulation compounds, or heat-resistant engineering adhesives. The need for predictable thermal behavior gets amplified in high-value, low-tolerance manufacturing operations, especially when device reliability is at stake.

    What Sets Our TMBP Apart from Other Phenolic Compounds

    Lots of people ask what distinguishes TMBP from the dense field of other dihydroxybenzenes. One glance at its structure shows the answer: crowding its two hydroxyls with four methyl groups, this molecule stubbornly resists oxidation and rearrangement far better than simple bisphenols like BPA or BPS. The methyl groups dampen reactivity at the ortho and para positions, boosting the ring’s thermal endurance while preventing undesirable crosslinks. Real-world example: our clients in lithographic chemical supply noticed higher yield stability running TMBP-based intermediates compared to traditional options.

    Compared to Bisphenol A, TMBP forms polyester and epoxy resins with notably higher glass transition temperatures and less embrittlement over time. Our own trials with injection-molded parts using TMBP-based polycarbonate confirmed dimensional retention over months of humidity cycling. This matters for electronics manufacturers fighting warpage and microcracking in fine-pitch circuit layouts.

    Biphenol and tetramethyl groups team up to produce not only chemical inertness, but also a viscosity profile that makes TMBP more forgiving during blending. That difference shows up in reactors: less fouling, fewer cleaning cycles, and better tool lifetime for downstream manufacturers. We’ve earned loyalty from compounders who once struggled with inconsistent melting in their extruders, and brought us problems — which we studied with materials cross-sections and real-time extrusion data.

    BPA and BPS have drawn scrutiny in recent years due to end-of-life toxicity and regulatory bans in certain consumer goods. TMBP has emerged as a valuable substitute, especially for applications stressed by heat or moisture, because of these methyl shields. The environmental persistence of TMBP traces back to our focus on removing metallic catalysts and hazardous sulfonic residues, which reduces the risk of contributing to harmful side-reactions in recycling or incineration.

    Facing Today’s Challenges and Supporting the Whole Supply Chain

    Running a chemical plant isn’t just about flowcharts and SOPs. Every production cycle faces curveballs: a heatwave causing minor moisture drift, raw material delays, or a sudden surge in demand. We balance these by keeping storage buffers and backup supplier contracts for cresols and oxidants. Our senior operators rotate weekly through QC and warehouse checks, drawing on decades of watching the small things that can blow up later. It’s tough work, but our customers count on us not just for spreadsheets but for stability and hands-on help.

    Global logistics shifts, particularly over the past four years, forced us to rethink packaging. Shipping in stainless drums and thick polybags guards the material against atmospheric moisture pick-up, which in turn protects against clumping and hydrolytic breakdown across long sea journeys. Even the smallest leak in these systems can ruin a hundred thousand dollars’ worth of product. We've added batch tracking at the pallet level, allowing real-time updates for our partners, and enabling traceability that stretches all the way back to final filtration.

    Recently, regulatory audit teams visiting our sites examined the interventions we've made at each stage: air quality monitors above reaction vessels, process cameras for real-time fault checks, and direct CO2 monitoring on scrubbers. We comply with evolving REACH and RoHS guidelines, and adjust material segregation practices routinely. These protocols aren’t just for checklists; they’re there so each customer can install our TMBP in sensitive production environments without second-guessing residue risk.

    Collaborating with End-Users for Application Development

    We encourage new project partners to reach out with challenging specs or performance requests. Some of our closest collaborations have been with clients needing modified TMBP grades, tuned for their reactors or downstream polymers. For instance, a major electronics OEM once shared recurrent gel formation in their high-speed extruders. We tested multiple anti-oxidation packages, drew on knowledge gained in pharmaceutical filtration, and developed a new pre-wash method that stabilized the resin yield. The customer’s line ran for weeks without stoppage, and a long-standing headache got scratched from their maintenance logs.

    Thermoplastic and thermoset resin producers occasionally ask us for low-sodium, low-potassium TMBP types. Our team invested in resin-lined piping and new acid-wash filter beds to shave down alkali metals. Lab analysis now routinely delivers readings below 1 ppm, meeting stricter electrical insulation criteria for Japanese and German partners. Feedback tells us that this delivers not only better insulation, but also extends molding tool lifetime — fewer issues with dielectric breakdown and surface pitting.

    We also help customers working on biodegradable or recyclable materials. Some eco-material startups asked for zero-halogen TMBP supply, so our R&D team adapted our synthesis chain, switching out quenching agents and drying media. They ran comparative LCA studies and found the environmental footprint lower — an outcome that persuaded them to scale up for mass production.

    Case studies like these show the daily give-and-take between production and application. By seeing the end-product results, our team gains insights on what tweaks in synthesis or final refining pay off in the real world. The partnership never ends with delivery; we stick with clients through scale-ups, new certifications, and after-market troubleshooting.

    Focus on Quality and Traceability

    Quality control starts before the first reactor loads. We test incoming cresol and other starting materials not just for purity, but also isotopic fingerprint and origin history. This prevents variation in large-scale campaigns, which matters for specialty grades like TMBP. Analytical chemists use GC/MS and HPLC for every batch, guaranteeing reproducibility in hydroxyl content and methyl placement. Beyond routine specs, we record and review any non-conformance event, so lessons reach the next production cycle promptly.

    Every shipment gets a full Certificate of Analysis with the actual measured results and analyst ID signatures. Customers sometimes audit our logs directly, looking at original run charts or raw instrument outputs. Newer clients often ask for retained reference samples, a practice we’ve maintained for over 15 years. If someone flags a problem downstream, our tracers find the parent batch within hours, offering support in root-cause analysis or corrective action planning.

    Aging studies on archived TMBP indicate little physical drift after 24 months at controlled room temperature. The color and purity parameters remain tight, and moisture uptake is minimal when our recommended packaging is followed. Customers with regulatory certification schedules find these data keep their audits moving smoothly, saving weeks of retesting or requalification procedures.

    Supporting Customer Safety and Regulatory Compliance

    Handling phenolic raw materials always takes caution. We engage with our partners’ EHS teams to guide storage, handling, and disposal. Each product package comes through with full hazard communication, and our staff field questions on appropriate PPE or spill containment. Over the years, we updated our safety documentation — responding to emerging guidance from regional authorities— to provide real answers rather than just legal boilerplate.

    Our plant response teams drill for quarter-turnover emergencies: spill drills, vapor containment exercises, and first-responder training. We encourage our customers to share any incidents and provide support for root-cause investigation (in one case, a warehouse mechanical failure in hot weather pushed internal drum pressure close to the limit; we provided remote monitoring guidance and dispatched spare containers for transfer). Rest assured, we share lessons learned with others, strengthening the wider ecosystem as a result.

    TMBP production produces waste that calls for responsible disposal. We continuously optimize solvent recovery and incineration, and follow up with annual third-party reviews. Tank residue and filter cake are channeled for licensed hazardous waste management, never landfilled or diluted down the drain. We maintain records that cover all these steps for as long as five years, and share summaries with major multinational partners on request.

    Pushing for Sustainability and Future Directions

    Our strategy for the next decade digs deep into sustainability and material circularity. We monitor green chemistry principles, sourcing plant-based cresols for some specialty batches, and evaluating solvent substitution trials in our pilot reactors. Each plant engineer submits two improvement proposals annually, feeding a steady trickle of process tweaks that pay off in smaller energy bills or tighter mass balances.

    TMBP’s future applications will likely include coatings for new battery types, flame retardant additives for composite panels, and tie-layer resins for flexible displays. Each of these paths brings unique challenges, from solubility in hybrid solvents to crosscompatibility with emerging biodegradable resins. Our technical liaison team works directly with clients exploring uncharted applications, offering both analytical support and practical solutions.

    We believe in the power of transparency. Decision-makers at manufacturing sites need access to hard data — and the open channel between their lab staff and our production chemists often unlocks performance leaps. If an R&D unit needs fast turnaround for a new grade or impurity profile, we retool our lines and work overtime to meet market demands.

    Our continuous process improvement culture leans into digital integration: chemical batch genealogy, warehouse robotics, and automated sample tracking. Each system aims to make our material more trustworthy and traceable, reducing risk not only for us but for every partner down the supply chain.

    Dedicated Service Built on Real Manufacturing Know-How

    At the end of the day, customers return to us not just for 2,2',6,6'-Tetramethyl-4,4'-Biphenol itself, but for the steady support that comes with long-term supply and honest troubleshooting. We don’t just ship barrels — we build relationships with plant engineers, R&D chemists, and sourcing teams who share our drive for quality and accountability. If a customer faces a process hiccup or a new integration challenge, chances are our team has seen a similar problem, and stands ready with ideas born from hard-won experience.

    Manufacturing is about more than just molecules. It’s a web of people, decisions, and shared knowledge. We’re committed to keeping the flow of genuine conversation open — whether that’s tracking your order, troubleshooting your lab run, or seeking feedback on our latest improvements. The journey of TMBP from raw material to finished product is complex, but we walk it every day, proud to apply lessons learned on the floor and in the field. That mindset continues to shape our future, batch by batch.