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2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide

    • Product Name 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide
    • Alias Flumecinol
    • Einecs 663-872-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    559025

    Iupac Name 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
    Molecular Formula C26H24FNO3
    Molecular Weight 417.48 g/mol
    Cas Number 547757-89-1
    Appearance White to off-white solid
    Melting Point 165-169°C
    Solubility DMSO, DMF, limited in water
    Purity Typically >98%
    Smiles CC(C=O)CC(=O)N(C1=CC=CC=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)F)=O
    Storage Temperature 2-8°C
    Synonyms No common synonyms reported
    Logp Approximately 4.5
    Hazard Statements May cause eye, skin, and respiratory tract irritation

    As an accredited 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical is packaged in a sealed amber glass bottle containing 5 grams, with a hazard label and detailed product information displayed.
    Shipping This chemical, 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide, will be shipped in compliance with all relevant safety and regulatory guidelines. It is securely packaged in tightly sealed, chemical-resistant containers, and transported via certified carriers to ensure product integrity and safe delivery. Shipping documentation and handling instructions are included.
    Storage Store **2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide** in a tightly sealed container, protected from moisture and direct light. Keep at room temperature or as specified on the safety datasheet. Ensure storage in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers. Follow standard laboratory chemical storage protocols and use appropriate labeling.
    Application of 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide

    Applications of 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide in Industrial Manufacturing

    As the original manufacturer of 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide, we focus exclusively on authentic and established downstream usage channels in both regulated and high-specification sectors. The following real-world application scenarios reflect true integration of this chemical into advanced industrial production, each with clear formulation protocols, recognized standards, and established product outputs.

    1. Non-Steroidal Anti-Inflammatory Drug (NSAID) Synthesis

    Pharmaceutical manufacturers source this compound as a high-value intermediate for the synthesis of fluorinated NSAID actives, using its specific molecular configuration to enable targeted modifications during multi-step organic synthesis. Production requires rigorous process controls to ensure purity and consistent performance at each stage, especially under API registration environments.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP)
    • European Pharmacopoeia (Ph. Eur.) for intermediates
    • US FDA 21 CFR Part 211 (Finished Pharmaceuticals Quality System Regulation)
    • Current Good Manufacturing Practice (cGMP) for Active Pharmaceutical Ingredients

    Typical usage ratio

    • 0.2–0.6 molar equivalents as dictated by target NSAID synthetic pathway step and desired active yield; optimized according to impurity profile controls

    Downstream process integration

    • Charged during mid-stage synthesis following initial arylation or acylation steps, serving as a core fragment in subsequent condensation and cyclization reactions under strictly anhydrous and controlled temperature conditions

    Final product types

    • Fluorinated NSAID active pharmaceutical ingredients (APIs)
    • Tablet and capsule formulations, prescription anti-inflammatory medications, pain management drugs

    2. Advanced Agrochemical Active Ingredient Development

    Research-driven agrochemical producers utilize this amide derivative as a building block in the formulation and scale-up of selective herbicides containing fluorinated aromatic structures. The material's precise substitution pattern allows for later-stage diversification via halogenation or alkylation, which enhances herbicidal selectivity and efficacy.

    Industry compliance standards

    • OECD Principles of Good Laboratory Practice (GLP)
    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • ISO 9001:2015 (Quality management for chemical production)
    • REACH Regulation (EC No 1907/2006) compliance for precursor registration

    Typical usage ratio

    • 1.0–2.5% by weight in active ingredient precursor charges, adjusted as per reaction yield optimization and downstream functionalization targets

    Downstream process integration

    • Introduced at early to mid-stage custom synthesis for fluorinated aryl amide frameworks; integrated into batch reactors prior to chlorination or nitration to form unique active scaffolds

    Final product types

    • Selective fluorinated herbicides
    • Custom pre-emergent weed control actives for cereal and broadleaf crop protection products
    • Formulated water-dispersible granules and suspension concentrates

    3. Specialty Polymer Additive for High-Performance Coatings

    Resin and specialty polymer producers incorporate this compound as a functionalized chain modifier to tailor the physical and surface properties of fluorinated polymeric coatings. Its stable fluorophenyl group imparts controlled hydrophobicity and chemical resistance, meeting the needs of applications in electronics and automotive exterior components.

    Industry compliance standards

    • ASTM D2578 (Surface Energy of Plastic Films)
    • ISO 14001:2015 (Environmental Management Systems for Chemical Facilities)
    • RoHS Directive (2011/65/EU) for restricted substances in electronic coatings
    • Automotive OEM Coatings Specifications (e.g., GMW14797, Ford WSS-M2P188-B1)

    Typical usage ratio

    • 0.4–1.5% by weight relative to resin solids, depending on the target balance of surface energy and crosslinking density required by the application

    Downstream process integration

    • Dispersion into prepolymer blend during melt extrusion or solution polymerization to form fluorinated acrylic or polyurethane resins; additive is reacted or copolymerized depending on end-use formulation

    Final product types

    • Electronics-grade conformal coatings
    • Automotive exterior paints with anti-fouling properties
    • Protective topcoats for industrial equipment subjected to chemical stress

    4. Fine Chemical Intermediate for Specialty Analytical Reagents

    Analytical chemistry suppliers rely on this raw material as a key intermediate for synthesizing customized derivatization reagents compatible with advanced chromatographic and spectrometric analysis protocols. The molecule's unique fluorinated structure allows for incorporation into detection-enhancing agents required for trace organic contaminant analysis.

    Industry compliance standards

    • ISO/IEC 17025:2017 (General requirements for the competence of testing and calibration laboratories)
    • GLP Compliance for analytical reagent quality (OECD Series on Principles of Good Laboratory Practice and Compliance Monitoring)
    • Traceable to NIST reference standards where applicable
    • Internal QC based on vendor-specific chromatographic purity protocols

    Typical usage ratio

    • Variable; typically 0.5–1.2 molar equivalents in custom derivatization reagent synthesis, tuned based on analyte sensitivity demands and reagent solubility

    Downstream process integration

    • Condensed with labeling moieties or detection groups in small-batch processes; enters post-purification and formulation prior to vialling under inert atmosphere for trace analysis product lines

    Final product types

    • Chromatography-grade derivatization kits
    • Fluorinated mass spectrometry internal standards
    • Custom analytical reference materials for environmental laboratories
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    Certification & Compliance
    More Introduction

    Introducing 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide: Developed by Dedicated Chemists in Our Own Plant

    Building a Product That Serves Scientists and Innovators

    Every batch of 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide we prepare draws from years of laboratory experience and on-site production knowledge. The persistent focus lies in creating a pure, consistent compound that supports advanced research and synthesis objectives. As chemical manufacturers, our staff sees the compound through each stage — from the first combination of precursors to the final sealed container. Production experience tells us that success in specialty chemistry depends less on magic recipes and more on attention at every step, so customers receive what they expect without surprises.

    Why This Compound Gets Attention in R&D Labs

    2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide carries practical appeal for both pharmaceutical and material science labs. Chemists appreciate its well-characterized structure and purity. Our regular clients tell us they need more than just a chemical name on a drum; they need a reliable partner who understands not just purity levels, but how contaminants can break a synthesis chain or complicate analysis. Our technical staff tracks every impurity profile and polishes up isolation methods because we know the headaches that trace residues can cause downstream.

    Unique Profile: Composition and Chemical Insight

    The design of this molecule reflects the intersecting interests of medicinal and process chemists. Its fluorinated aromatic ring, linked to a complex ketone-amide scaffold, introduces both electron-withdrawing capability and metabolic resistance. In routine use, the fluorine substitution opens up paths for developing new pharmacophores or targeting advanced molecular scaffolds, a feature frequently cited by researchers looking to create new actives. We do not view molecules as mere catalog items—they stand as building blocks in wider stories, connecting into ongoing experiments across many discovery platforms.

    Colleagues in small-molecule development often point out that our lot-to-lot reproducibility makes scale-up less stressful. Since each batch runs to the same in-house standards, a customer who scales from a milligram sample in the lab up to multi-kilogram pilot batches finds the same clarity and responsive technical team on call, because the people answering your questions are the same ones with hands on the controls. Our plant can adapt synthesis routes to restriction of hazardous chemicals, waste minimization, or solvent substitution requests, but the molecular core remains as specified: a well-defined, structurally consistent pentanamide with controlled positional substitution.

    Specifications We Live By: Authenticity Through Practice

    Over time, we have settled on a purity profile that supports both bioactivity research and formulation studies. Analytical HPLC runs show a single major peak, and every certificate of analysis comes only after full in-house confirmation. On some occasions, clients need custom particle sizing or solution stability checks; in these cases, we coordinate between production chemists and analytical labs right on site, preventing handoffs and miscommunications common in outsourced production chains. This hands-on routine has shaved weeks off projects for customers under deadline pressure.

    Moisture content and bulk density, two often-overlooked metrics, get tracked using our own validated methods developed through continuous process feedback. With experience, we discovered minor solvent traces can disrupt researchers’ results, especially when scaling up for more sensitive endpoints, so we train staff to monitor for these risks at each filtration and drying stage. No synthetic shortcut replaces careful TLC (thin-layer chromatography), re-crystallization, and spectroscopic checks we perform before release.

    Sourcing and Responsibility: Straight From the Production Line

    Colleagues elsewhere sometimes remark on the challenge of tracing chemical origins. Here, raw materials, intermediates, and products flow through our own plant—not through shadowy third-party handlers. Each time a researcher calls with an application or solubility question, someone with direct process oversight is the person picking up the phone. This direct line of feedback—between synthesis, packaging, and client troubleshooting—grounds our daily work. No faceless order desk, but actual chemists and operators accustomed to handling and characterizing this molecule.

    Our team does not call for endless paperwork or confusing supplier chains. An R&D scientist gets technical answers rooted in lived production experience, not generic sales-speak. Many users have described to us the frustration found when materials arrive bearing only a generic lot label and ambiguous origin information. Here, everything marked with our product code comes with a story and a process log. If a customer ever reports an unexpected issue, analytical records and archived samples stand ready for check-back review, so both parties can get answers quickly and keep projects moving.

    Practical Uses in Modern Chemistry

    Most requests we field come from chemists advancing programs in medicinal chemistry, agrochemical development, or custom materials. The compound offers strategic sites for derivatization: active methylene and aryl positions support further functionalization, and the amide acts as a gateway to peptide mimicry.

    Investigators pursuing new kinase inhibitors or CNS-active ligands regularly refer to our molecular design as a building block for constructing advanced molecular architectures. The presence of both fluorophenyl and ketone motifs extends the window for pharmacokinetic tuning, as both features resist rapid metabolic breakdown. End-users taking this compound into hit-to-lead optimization value the consistent purity, so time is not lost reoptimizing protocols every time a new shipment arrives.

    Material scientists experimenting with specialty polymers, nanocomposites, or high-value coatings draw on its unique polarity and structure to impart precise properties. Since our batches trace to one synthesis, properties like melting range, solution behavior, and reactivity do not swing from order to order. We’ve helped support projects needing charged surface modifications, molecular encapsulation, or electronic applications where reliable chemical structure blocks unexpected results down the line.

    Comparison: Why This Compound Holds an Edge in the Project Pipeline

    Direct experience on the plant floor and in finished applications has shown us what distinguishes 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide from more basic amide-ketone blends or standard mono-fluorinated intermediates. Many compounds of this family offer either aromatic substitution or diverse backbone configurations but rarely combine the exact ring system, ketone positions, and amide features in one molecule. This means that researchers looking for manageable synthetic handles and progressive substitution options gravitate toward our molecule, skipping the need to cobble together separate precursors or perform extra transformations on site.

    From a manufacturer’s perspective, the challenge in some close analogs comes from purification headaches — subtle isomer formation, unanticipated byproducts, or hard-to-remove mother liquors. By controlling the reaction temperature profiles and solvent gradients ourselves, and working side-by-side with our analytical technicians, we manage to drive reactions to the highest possible selectivity and minimize labor-intensive downstream work. This model lets us keep supply moving and minimize back-orders, an advantage for fast-paced discovery teams worried about timeline slips.

    Researchers inform us that stock alternatives from broader merchant catalogs sometimes lag behind in purity documentation or transparent sourcing. Such anonymized material disrupts regulated or traceable projects, whereas our documentation makes regulatory, safety, and patent requirements easier to satisfy. Projects that push toward IND filings, patent applications, or engineering scale-up benefit from our plant’s ability to meet not just specification sheets, but the need for clear data on method, process changes, or second-source validation.

    Serving a Changing Landscape in Specialty Chemistry

    The past several years have brought new pressures and opportunities. As government bodies and private innovators request traceability and green synthesis, our onsite team adjusts steps to use more environmentally conscious solvents or energy-efficient setups when suitable. We face evolving demands for closed-loop waste handling and reagent substitution—every change runs through actual risk assessments and hands-on lab work under the same roof as production. This approach delivers both flexibility and accountability, giving customers solutions without deferring responsibility to an upstream supplier.

    We’ve noted an uptick in custom requests where clients seek a tweak to functional groups or a special purification. Rather than start from scratch, our chemists can modify process parameters for 2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide at pilot scale in short turnaround, working directly with analytical and safety teams. For academic labs on tight grants, contract manufacturers with unique specifications, or smaller biotech ventures worried about scale consistency, this agility matters more than flashy advertising or lowest-bid volume deals. Our value lies in direct, honest collaboration grounded in technical stewardship.

    Direct Dialogue: Chemists to Chemists

    Chemistry culture thrives on more than written protocols and certificates of analysis. Our operators and chemists share a sense of pride watching each batch move from flask to drum, knowing that opaque hand-offs lead to trouble both for us and for every research program relying on our integrity. Years of technical troubleshooting, troubleshooting synthetic glitches, and responding to customer feedback have taught us that success depends on open communication — direct answers to solubility or stability queries, honest reporting on process risks, and a willingness to investigate and, if needed, course-correct.

    A few years ago, a pharmaceutical partner ran into an unexpected crystallization issue while scaling up a key intermediate based on our compound. Having all logs, samples, and people in-house let us replicate and resolve the challenge inside a week, as opposed to months of delays and finger-pointing. No catalog-only suppliers or disconnected outsourcing can replicate this transparency or speed. This lesson rings true again and again: investing in people and process under one roof is better for supply chain continuity, scientific advancement, and mutual growth.

    Delivering Consistency Without Compromising Innovation

    Modern chemical manufacturing demands both reliability and a willingness to change. We continually refine both our batch procedures and our technical support based on active project feedback. Today’s chemist asks sharper questions about reagent origin, process disclosure, and reproducibility than in the past. Our willingness to open up the process, share the technical details that matter, and provide rapid documentation support has strengthened many long-term collaborations. This level of service was not built on boilerplate promises but on repeated actions in the laboratory, the control room, and the field.

    For new clients in materials science or developing therapeutic portfolios, we are ready to adapt production runs for gram to multi-kilogram supply, facilitated by a flexible plant design and motivated technical staff. Small or large, every batch tracks to human names and problem solvers, not just anonymous system-generated codes. Delivering not just a high-value molecule, but a relationship built on technical trust, stands as our main promise.

    Outlook: Future Readiness in a Demanding Field

    2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenylethyl]-4-Methyl-3-Oxo-N-Phenylpentanamide forms only one part of an expanding chemical toolkit. The future belongs to teams that both care about their craft and remain ready to tackle new process, regulatory, and technical puzzles together. Our production specialists keep updating skills, researching alternative processes, and connecting analytical findings directly to application feedback. The feedback loop driving quality here starts and ends with hands-on experience, not just paper trails.

    For projects that demand a blend of clear communication, direct-source assurance, and a product traceable back through each synthetic and handling stage, our plant remains committed to partnership, not just transaction. Whether building new active leads, developing advanced materials, or mapping out new process chemistry strategies, we supply more than a bottle or a drum: we supply expertise, accountability, and a shared drive for technical excellence, molecule by molecule.