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2,2,3,3-Tetrafluoropropyl Iodide

    • Product Name 2,2,3,3-Tetrafluoropropyl Iodide
    • Alias CF3CF2CH2I
    • Einecs 206-970-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    905361

    Chemical Name 2,2,3,3-Tetrafluoropropyl Iodide
    Molecular Formula C3H3F4I
    Molar Mass 243.95 g/mol
    Cas Number 460-37-1
    Appearance Colorless liquid
    Boiling Point 80-82 °C
    Density 2.09 g/cm³
    Refractive Index 1.388
    Solubility Insoluble in water
    Purity Typically 98% or higher

    As an accredited 2,2,3,3-Tetrafluoropropyl Iodide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100g, with secure screw cap; clear hazard labeling for toxicity and volatility; tightly sealed for shipment.
    Shipping 2,2,3,3-Tetrafluoropropyl Iodide is shipped as a hazardous material in well-sealed, corrosion-resistant containers, protected from light and moisture. It should be transported under temperature-controlled conditions, clearly labeled with hazardous and chemical handling information, complying with relevant international shipping regulations, including UN identification numbers and safety requirements for organoiodide compounds.
    Storage 2,2,3,3-Tetrafluoropropyl Iodide should be stored in a tightly sealed container under an inert atmosphere, such as nitrogen or argon, to prevent moisture and air exposure. Store in a cool, dry, and well-ventilated area away from direct sunlight, heat sources, and incompatible materials like strong oxidizers or bases. Handle and store using appropriate chemical safety protocols.
    Application of 2,2,3,3-Tetrafluoropropyl Iodide

    Applications of 2,2,3,3-Tetrafluoropropyl Iodide in Industrial Manufacturing

    As a committed manufacturer, we supply 2,2,3,3-Tetrafluoropropyl Iodide to specialty fluorochemical producers engaged in targeted high-performance industries. Below we present real, established usage scenarios supported by industry standards, clear formulation roles, and integration into downstream workflows, serving advanced materials and chemical manufacturers worldwide.

    1. Fluorinated Refrigerant Intermediate Synthesis

    Producers utilize this compound as a key building block in synthesizing new-generation hydrofluoroolefin (HFO) refrigerants known for their low global warming potential. Engineered for reactivity and precise integration, this iodide enters fluorochemical synthesis routes to achieve target molecular architectures required by environmental standards for refrigeration gases.

    Industry compliance standards

    • AHRI Standard 700 (Refrigerants Purity Specifications)
    • ISO 817 (Refrigerants - Designation and Safety Classification)
    • EN 378 (Refrigerating Systems and Heat Pumps - Safety and Environment)
    • REACH Regulation (EC 1907/2006) for fluorochemical handling

    Typical usage ratio

    • 10-25 mol% as halogen exchange substrate in step-growth synthesis; precise charge determined by stoichiometry and target refrigerant molecule

    Downstream process integration

    • Batch addition during halogenation or dehydrohalogenation in closed fluorination reactors
    • Controlled feed in multi-step fluorination and subsequent purification stages

    Final product types

    • Hydrofluoroolefin refrigerants (e.g., HFO-1234yf, HFO-1234ze)
    • Blended low-GWP refrigerant mixtures

    2. Fluorinated Agrochemical Synthesis

    Active ingredient manufacturers use this compound for introducing tailored fluorinated moieties into agrochemical intermediates, improving bioactivity and environmental persistence. Upgrading molecular frameworks for regulated pesticide and herbicide actives relies on selective iodination and subsequent fluorination steps driven by this material.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 17025 (Testing and Calibration Laboratories - Chemical Analysis)
    • European Regulation (EC) No 1107/2009 for Plant Protection Products

    Typical usage ratio

    • Typically 8-18 mol% relative to core intermediate; actual proportion varies per targeted fluoroalkyl group and conversion yield

    Downstream process integration

    • Charge during halogen transfer steps under anhydrous, inert conditions as a precursor for targeted functional group introduction

    Final product types

    • Pyridine-based fluorinated herbicides
    • Haloalkyl-substituted insecticidal actives
    • Seed treatment chemicals containing fluoroalkyl groups for enhanced uptake

    3. Fluorinated Pharmaceutical Intermediate Production

    Pharmaceutical ingredient firms leverage this iodide to create specialized fluorinated scaffolds used in active pharmaceutical ingredient (API) synthesis. The product helps insert specific fluorine or iodine substituents at late-stage steps, shaping pharmacokinetic profiles in compliance with rigorous quality frameworks.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • USP and Ph. Eur. Monographs (API specifications)
    • FDA CFR Title 21 (GMP in Drug Manufacturing)

    Typical usage ratio

    • 6-14 mol% relative to precursor, adjusted based on desired fluorine incorporation and reaction selectivity

    Downstream process integration

    • Introduced during alkylation or halogen-exchange steps in multi-step API syntheses under strictly controlled conditions

    Final product types

    • Fluorinated pyrazole or pyridine pharmaceutical intermediates
    • Oncological and CNS drug precursors containing trifluoromethyl groups

    4. Specialty Fluoropolymer Precursor Manufacturing

    Manufacturers of advanced fluoropolymer resins source this compound as a chain-transfer agent or comonomer precursor during emulsion or suspension polymerization. The material's specific iodine terminus facilitates controlled molecular weight adjustment and fluoroalkyl group introduction, ultimately influencing end-use polymer properties such as chemical resistance and dielectric performance.

    Industry compliance standards

    • ISO 9001 (Quality Management Systems for Polymer Plants)
    • ISO 14001 (Environmental Management Systems for Chemical Processes)
    • REACH Regulation (EC 1907/2006) for all fluoropolymer raw materials

    Typical usage ratio

    • 0.2-2 wt% as chain-transfer agent; dosage depends on polymerization kinetics, reactor scale, and targeted end polymer specifications

    Downstream process integration

    • Dosed into monomer feed or pre-mix prior to onset of radical-initiated polymerization under inert atmosphere

    Final product types

    • Dielectric fluoropolymer films
    • Fluoroelastomer gaskets and seals
    • Battery separator membranes for lithium-ion applications

    5. Electronic-Grade Fluorochemical Precursor Utilization

    Producers of microelectronic processing agents employ this raw material as a functionalized building block to manufacture ultra-high purity etchants and plasma processing fluorocarbons. The iodide's defined structure and reactivity enable the creation of specialty gases and surface modifiers that meet stringent semiconductor fabrication purity and property requirements.

    Industry compliance standards

    • SEMI C3 (Specifications for Gases Used in Semiconductor Processing)
    • ISO 14644 (Cleanroom and Controlled Environments)
    • RoHS Directive (2011/65/EU) for electronics substances

    Typical usage ratio

    • 0.5-5 mol% in fluorination reaction mix, optimized for selectivity and impurity control in specialty fluid synthesis

    Downstream process integration

    • Meticulous addition at functionalization or fluorination stages; followed by multi-step purification prior to electronic-grade specification

    Final product types

    • Fluorinated plasma etching gases (e.g., tailored perfluorinated alkanes or alkenes)
    • Electronic-grade surface treatment agents for semiconductor wafers
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    Competitive 2,2,3,3-Tetrafluoropropyl Iodide prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    High-Purity 2,2,3,3-Tetrafluoropropyl Iodide: Expertise from a Dedicated Chemical Producer

    Introduction to Our 2,2,3,3-Tetrafluoropropyl Iodide

    Producers in fine fluorochemicals know that certain building blocks enable entire product families. 2,2,3,3-Tetrafluoropropyl Iodide offers an essential step for many specialty and intermediate applications. In our production facilities, we devote significant resources to ensuring that each batch meets stringent purity demands. Our manufacturing team tracks each phase from input substance to packaged product. Bottom lines begin with repeatable quality output, and that means controlling every detail in the process.

    Meeting Modern Application Needs

    Researchers and manufacturers often need a source for perfluorinated intermediates that deliver not just molecular accuracy, but consistent performance. Halogenated iodides are especially valuable as alkylating agents or for introducing perfluoroalkyl groups into complex frameworks. Customers use our 2,2,3,3-Tetrafluoropropyl Iodide with confidence in critical syntheses—be it for pharmaceuticals, crop protection actives, new battery chemistries, or next-generation functional materials.

    Contamination in such compounds doesn’t stay hidden—it damages yields or distorts reactions downstream. By controlling water and halide impurities and using dedicated equipment, we help mitigate side reactions and downstream removal burdens. Over years, we’ve learned where bottlenecks appear, so we refine our purification steps for every batch.

    Model and Specifications

    We manufacture 2,2,3,3-Tetrafluoropropyl Iodide under tightly monitored reaction and purification conditions. For most customers, we offer a specification of at least 98% purity by gas chromatography. Each delivery comes in amber glass drums or lined containers, safeguarding against UV or moisture ingress. Our technical team inspects every drum for seal integrity and proper labeling.

    The material’s physical profile—colorless to pale straw liquid, boiling near 92°C at atmospheric pressure—remains solidly consistent batch after batch. Careful control of reaction time, temperature, and quenching protocols has allowed us to minimize acid and fluoride residuals. We built protocols to ensure that hydrolyzable fluoride stays below detectable limits and total non-volatile matter cannot impair downstream processing.

    2,2,3,3-Tetrafluoropropyl Iodide demands attention in handling and storage. Even a few ppm of metallic contaminants can cause problematic decomposition or color changes. Our experience with bottling and long-haul logistics ensures the integrity you need from loading bay to R&D lab or production scale application.

    Our Experience in Fluoroalkyl Iodide Manufacturing

    Consistent output does not stem from luck or random trial. Synthetic organic manufacturers thrive when core steps run repeatably. Our team refined process parameters over years of manufacturing this class of fluorinated iodides. Learning to know where byproducts emerge—and how easily handling impacts final purity—takes repetition combined with keen technical awareness.

    Customers often point out the trace impurities in other sources of halogenated intermediates. Unfiltered residues or volatile halides can cause batch failures. On the line, we run regular chromatographic and NMR checks, searching for those minor byproducts. Throughout the process, our technical production workers log every change. Only these floor-level controls allow us to build long-term partnerships with users who value quality.

    The fluoroalkyl iodide’s shelf life depends on low impurity buildup and protective packaging. Under suitable conditions, our iodide remains ready for complex syntheses for months without decompressing or yellowing. This reliability is a direct result of decades of continuous plant improvement and the painstaking tweaks one only learns by producing it directly.

    Key Differentiators vs. Other Products

    Companies sometimes substitute other perfluoroalkyl iodides or bromides, either for cost reasons or due to temporary supply shifts. We have seen what these swaps can do: frequently, alternative halides demonstrate lower reactivity profiles or introduce extra purification steps after reactions. Our 2,2,3,3-tetrafluoropropyl iodide couples strong leaving group character with high molecular weight, helping syntheses to proceed with cleaner endpoint profiles.

    Compared to shorter-chain analogs, the three-carbon backbone here gives a unique blend of volatility and reactivity. Among other halides, iodine imparts greater reactivity—which matters for late-stage functionalization of complex molecules, and for creating tailored intermediates with robust yields. Our clients tell us that switching from less carefully made lots, or using materials stored in non-specialized drums, often requires expensive analytical troubleshooting.

    Industrial users point out the trouble that comes with inconsistent supply chains. Imports routed through multiple traders or poorly controlled facilities bring not just risk, but real downtime in process development cycles. As a direct producer, we build relationships both to secure raw materials and to foster a feedback loop: we learn from your process challenges, identify potential improvements, and pioneer adjustments that keep purity high and byproduct formation to a minimum.

    Sustainable Operations and Product Responsibility

    Sustainability now cuts across every specialty chemicals market. For us, handling fluorinated organics means stringent controls—right down to solvent recovery, safe air emissions management, and responsible effluent treatment. We engineered our system to recover and recycle solvents wherever possible. Our waste minimization programs audit every ton of input and output, aiming to reduce both environmental load and unnecessary cost.

    Iodinated intermediates, while valuable, demand thoughtful transport and emergency control planning. We store all iodide raw materials and final stock in specialized containment spaces, with continuous air monitoring. Training and tightly controlled handover protocols help prevent any accidental release or worker exposure. In addition, we routinely gather data to ensure our on-site controls align with both local regulations and global standards, from workplace safety to chemical stewardship.

    Fluorinated compounds must not escape containment. Our manufacturing staff reviews all lines weekly, searching for leaks or signs of vapor loss. Small daily checks—documented, not just spoken—have prevented emissions and potential clean-up events. No certificate or brochure can replace years of boots-on-floor vigilance. We welcome in-person audits and technical due diligence, reflecting our belief in continuous improvement and open communication with discerning end-users.

    Tailored Solutions and Ongoing Support

    Every synthesis challenges traditional standards. Research into new pharmaceuticals, crop protection active ingredients, or performance coatings often demands that intermediate specs shift quickly mid-project. We’ve worked with customers who encountered unplanned solubility hurdles, or who found trace acid leftover from other vendors causing unexpected side product formation. Our team provides samples for scale-up evaluation and stays on-call to interpret any obscure analytical results you encounter.

    We built an internal database for deviations, letting us track customer complaints, minor failures, or even off-color batches that did not meet strict expectations. Lessons learned here transform directly into process controls: improved distillation ratios, extended drying cycles, or modified container cleaning protocols. Where it really counts is in flexibility—if a long-term user needs a two-liter qualification sample or an adjusted impurity profile for a novel application, we invest the time rather than force them into a rigid, catalog-bound process.

    Several long-term partners credit us with reducing their analytical headaches. This feedback does not emerge by chasing cost or minimum order quantity. Rather, it stems from a factory culture that remembers production quality, not sales volume, keeps customers loyal and innovation flowing.

    Safe Handling and Logistics

    Moving fluoroalkyl iodides from our plant to your laboratory or facility presents real technical challenges. Our logistics team understands the need for rapid, uninterrupted temperature stability. Pallets are shrink-wrapped in-house to forestall accidental exposure. Containers ship with desiccant packs and temperature monitors when freight distances or customs durations might permit transit risk.

    We share technical handling guides with all our industrial users, drawn from incidents logged over years. Damaged drums in transit remain rare—for each event, we log, investigate, and refine packing practices. It’s not uncommon for new customers to underestimate the effect of ambient humidity, especially when a shipment spans weeks in variable climates, so we advocate for just-in-time ordering and buffer stock protocols.

    We regularly update our handling and hazard training, and our shipping partners complete required modules for hazardous materials management. Customers often reach out with storage questions as they scale from laboratory glassware to pilot reactors. We share best practices—not as an afterthought, but as an integrated part of technical collaboration.

    Technical Collaboration: From Lab to Plant

    Projects using 2,2,3,3-tetrafluoropropyl iodide rarely stay at bench-top scale for long. The demand for greater batch sizes brings new headaches, from heat management to impurity carryover. Our team supports scale-up efforts, joining conversations on crystallization, solvent handling, or target purity enhancements. By drawing on field experience, we aid partners looking to streamline their own routes toward next-gen molecules.

    Whether a formulation challenge arises, or a pilot run encounters solvent compatibility issues, our technical support team stays directly engaged. Open data exchange, timely samples, and precise feedback form our process for keeping every gram and liter at the required performance. We tackle each new project as an opportunity to refine product and process, building toward mutual success.

    Conclusion: Delivering Manufacturer-Level Confidence

    Working hands-on with 2,2,3,3-tetrafluoropropyl iodide over years has taught us a few core truths. Supply consistency, purity, and real production expertise matter for anyone using halogenated intermediates for advanced applications. By controlling our process from raw material to drum, making every correction logged and shared, and learning with customers as needs evolve, we offer not just a compound—but a partnership built on trust, skill, and a culture of constant improvement.

    Feedback from laboratories, R&D projects, and industrial partners guides us each production day. Direct, in-plant experience shapes every improvement we make. Those seeking 2,2,3,3-tetrafluoropropyl iodide that holds its line in advanced chemical syntheses—without costly surprises, shipment delays, or analytical headaches—find value in our approach and in the results we work to deliver, batch after batch.