Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

2-(1-Cyclohexenyl)Ethylamine

    • Product Name 2-(1-Cyclohexenyl)Ethylamine
    • Alias Chinylephrine
    • Einecs 624-42-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    226197

    Chemicalname 2-(1-Cyclohexenyl)Ethylamine
    Molecularformula C8H15N
    Molarmass 125.21 g/mol
    Casnumber 3986-55-0
    Appearance Colorless to pale yellow liquid
    Density 0.917 g/cm3
    Boilingpoint 214-216 °C
    Meltingpoint -10 °C
    Solubilityinwater Slightly soluble
    Refractiveindex 1.497
    Purity Typically ≥97%
    Synonyms 2-(1-cyclohexen-1-yl)ethan-1-amine
    Flashpoint 84 °C
    Storagetemperature Store at room temperature

    As an accredited 2-(1-Cyclohexenyl)Ethylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100 grams; screw cap with tamper-evident seal, chemical label with hazard warnings, product name, and batch number.
    Shipping 2-(1-Cyclohexenyl)ethylamine should be shipped in secure, sealed containers, protected from moisture and extreme temperatures. Ensure compatibility with packaging materials. Clearly label containers with hazard information. Transport must comply with local, national, and international regulations governing amines and chemicals. Use secondary containment and provide necessary documentation for safe and legal shipping.
    Storage Store 2-(1-Cyclohexenyl)ethylamine in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers and acids. Keep the container tightly closed and protected from direct sunlight. Use appropriate chemical-resistant containers and ensure proper labeling. Observe standard procedures for handling amines, including using gloves and eye protection to minimize exposure.
    Application of 2-(1-Cyclohexenyl)Ethylamine

    Applications of 2-(1-Cyclohexenyl)Ethylamine in Industrial Manufacturing

    As the original developer and manufacturer of 2-(1-Cyclohexenyl)Ethylamine, we support a range of industrial partners with proven supply for critical downstream sectors. Below we detail application-specific integration across select mature markets, addressing practical regulatory adherence, formulation approach, process inputs, and targeted end products.

    1. Pharmaceutical Intermediate for Antihypertensive APIs

    Leading pharmaceutical manufacturers specify this cyclohexenyl ethylamine derivative as a key intermediate in the synthesis of select antihypertensive active pharmaceutical ingredients, specifically targeting multi-step reactions involving amination protocols. Quality oversight and traceability remain paramount, with strict adherence to global standards throughout the conversion of this raw material to drug-quality intermediates and ultimately to regulated APIs commercialized under various cardiovascular therapies.

    Industry compliance standards

    • Good Manufacturing Practice (GMP) – ICH Q7
    • USP–NF (United States Pharmacopeia–National Formulary) monograph requirements for intermediates
    • European Pharmacopoeia general requirements
    • US FDA 21 CFR Part 210/211 (for process controls and traceability)

    Typical usage ratio

    • Stoichiometric levels, usually 0.9–1.1 molar equivalents relative to acyl donor or precursor, adjusted based on yield optimization and secondary impurity profile controls

    Downstream process integration

    • Feeds into reductive amination or substitution step after initial cyclohexene ring functionalization; batch-wise or continuous flow integration based on process scale

    Final product types

    • Antihypertensive bulk APIs (e.g., hydralazine analogs, cyclohexylamine derivatives)
    • Late-stage key intermediates supplied to global pharmaceutical companies
    • Finished oral solid dosage forms following downstream API processing

    2. Synthesis of Agrochemical Active Compounds

    Agricultural chemical formulators use 2-(1-Cyclohexenyl)Ethylamine as a building block for certain herbicide and fungicide actives where selective amine reactivity is required. Integration focuses on ring-amine functionality for crop protection chemistry, where adherence to agricultural safety and environmental regulations is rigorously tested, and finished actives undergo full field residue and toxicology evaluation prior to commercial sale by downstream clients.

    Industry compliance standards

    • FAO/WHO International Code of Conduct on Pesticide Management
    • OECD Environment, Health and Safety publications for chemical manufacture
    • REACH Registration (EU) and US EPA TSCA Inventory requirements
    • ISO 9001:2015 (Quality Management System for chemical synthesis control)

    Typical usage ratio

    • Employed at 3–7% by weight in precursor blend; ratio may shift based on desired selectivity and downstream purification efficiency in multi-step synthesis

    Downstream process integration

    • Added to condensation or Michael addition step in micronutrient-active manufacturing, prior to downstream chlorination, sulfonation, or alkylation

    Final product types

    • Technical grade herbicides based on cyclohexyl amine backbones
    • Fungicide actives for post-emergence crop application
    • Agrochemical intermediates for further derivatization

    3. Polyurethane Catalyst Component

    Polyurethane foam and elastomer producers utilize the reactive amine group as a catalyst or ancillary curative in specialty polymer systems requiring controlled reactivity profiles. By introducing this material at precise points in the formulation, manufacturers drive consistent polymer chain formation and improve fine cellular structure in finished foams—subject to rigorous in-process analytical and environmental controls accredited by global quality organizations.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management for chemical facilities
    • ASTM D3574 (Standard Test Methods for Flexible Cellular Materials)
    • REACH and TSCA pre-manufacture notifications for polymer additives
    • China GB/T 26701 compliance for chemical catalysts in PU production

    Typical usage ratio

    • 0.05–0.5% by weight relative to total isocyanate/polyol system, optimized for catalyst activity and downstream emissions minimization

    Downstream process integration

    • Incorporated alongside amine blend just prior to isocyanate addition in foam production, or directly mixed into prepolymer stage in elastomer lines

    Final product types

    • Flexible and rigid polyurethane foams for automotive seating and packaging
    • Molded PU elastomer parts for industrial applications
    • Custom performance foams used in specialty building materials

    4. Modifier for Industrial Rubber Compounding

    Specialty rubber and elastomer compounders integrate 2-(1-Cyclohexenyl)Ethylamine to enhance vulcanization kinetics and modify mechanical properties of high-performance rubber blends, especially in tires and industrial rollers. Downstream QC teams monitor process input, ensuring compounded batches comply with national material standards for automotive and heavy industry, including traceable documentation from raw material receipt to final curing steps.

    Industry compliance standards

    • ISO 9001/TS 16949 for automotive rubber production
    • ASTM D2000 (Standard Classification System for Rubber Products)
    • China GB/T 528–2009 for vulcanized rubbers
    • REACH SVHC declaration for process additives

    Typical usage ratio

    • Typically 0.1–1.2 phr (parts per hundred rubber), calibrated by compounding engineer based on desired crosslink density and end-use dynamic property targets

    Downstream process integration

    • Directly dispersed within rubber matrix pre-vulcanization, with compatibility checks in internal mixer before introduction to the curing press

    Final product types

    • Automotive tires for performance and industrial segments
    • Heavy-duty conveyor belts for logistics and mining
    • Resilient roller coverings for printing and industrial processing lines

    5. Fine Chemical Precursor for Fragrance Ingredients

    Fragrance and aroma producers rely on the selectivity of this amine in cyclohexyl-based skeleton construction for subsequent transformation into specialty musk and floral note ingredients. Downstream sites verify batch purity and low residual content to meet global IFRA and regional quality codes, with clear traceability from raw material sourcing through to blending and packaging for perfumery or flavor use.

    Industry compliance standards

    • IFRA (International Fragrance Association) Amendment Codes
    • ISO 9001:2015 for ingredient traceability
    • US FDA 21 CFR Part 172 (for flavor and fragrance ingredient limits)
    • EU Regulation (EC) No 1334/2008 for flavorings

    Typical usage ratio

    • 0.5–5 mol% relative to downstream aldehyde or ketone in musk precursor synthesis, modified based on olfactory intensity requirements and yield from subsequent cyclization steps

    Downstream process integration

    • Introduced into cycloalkylation or amination reaction prior to key oxidations during aroma intermediate synthesis, followed by purification and blending

    Final product types

    • Cyclohexyl-derived musks and specialty aroma ingredients
    • Fragrance oil concentrates for personal care goods
    • Flavor additives complying with food-grade standards
    Free Quote

    Competitive 2-(1-Cyclohexenyl)Ethylamine prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    2-(1-Cyclohexenyl)Ethylamine: Sourcing Innovation Straight from the Factory Floor

    Understanding 2-(1-Cyclohexenyl)Ethylamine From the Manufacturer’s Perspective

    Every day in a chemical plant brings a new perspective on specialty compounds like 2-(1-Cyclohexenyl)Ethylamine. Our team has managed every step from raw material selection to the last filtration, so we see more than just an inventory item. This chemical doesn’t come off the line by accident; it grows out of a direct process built for reliability and consistency in an industry that doesn’t forgive guesswork.

    2-(1-Cyclohexenyl)Ethylamine doesn’t just quietly fill a niche. You see its significance in the steady requests from research laboratories, pharmaceutical developers, and fine chemical synthesis companies. On the factory floor, teams run the reactor with cyclohexenyl derivatives and control amination conditions with the same hands that test purity, because any off-spec batch creates real costs—both in time and customer trust.

    Model and Specifications Rooted in Real Production

    Unlike bulk commodity chemicals, 2-(1-Cyclohexenyl)Ethylamine always starts with the question: what grade does the end-user actually need? Our standard batch, for instance, delivers a minimum purity of 98%, based on years of feedback where a margin lower triggered downstream headaches for our partners. Each run is monitored for moisture, acid value, and residual solvents because our own chemists hate reruns caused by invisible contaminants.

    Granule size and coloration can vary from one series to the next, a reminder that even small processing tweaks—say, the heat profile on a specific reactor—find their way into what the customer sees in the drum. In practice, some clients ask for tighter specification windows for applications in custom synthesis, others use standard grade in fields like intermediate production for agricultural chemicals.

    Factory Floor Insights on Uses and Applications

    Our experience producing 2-(1-Cyclohexenyl)Ethylamine traces directly into R&D pipelines for next-generation compounds. On the medical side, seasoned process engineers find that this amine’s structure makes it a solid scaffold for producing new pharmaceutical intermediates, especially those moving past the bench-scale phase. The molecule’s balance of cycloaliphatic stability and accessible amine functionality helps downstream chemists attach other key groups, whether they're building antihypertensive candidates or developing CNS-active agents.

    Across other sectors, the compound steps into fine chemical manufacturing. We get regular orders from companies making specialty coatings or flavor and fragrance intermediates. Here, they prize consistent reactivity, predictable melting point, and the absence of interfering side-products—details that get baked into process SOPs and which only show up once you’ve moved real tons, not lab-scale vials.

    Production Process: From Feedstock to Finished Drum

    Our production process centers on a tightly engineered catalytic amination. Skilled technicians charge reactors with carefully sourced 1-cyclohexene, run pressure-controlled hydrogenation, and oversee a direct alkylation with ethylamine. There’s no way to shortcut sample analysis and fraction collection. The last time anyone downsized quality checks, half a batch wound up non-compliant for pharmaceutical use. We keep processes lean but never at the expense of finished batch reliability.

    We also fine-tune drying and storage—all the way down to drum linings—because residual moisture and trace metals undercut downstream reactivity. Every step reflects the reality faced by practitioners: if the packaging lets in too much air, users get degradation; if drums pick up chloride residues, users see ghost peaks in GC. Paying attention to these factory-level details protects value for every stakeholder relying on a genuinely high-integrity input.

    Why Purity and Batch Consistency Drive Real-World Value

    Buyers shopping outside the primary manufacturing route sometimes encounter off-batch product. Maybe it’s got elevated aldehyde content, or there’s an extra isomer sneaking past QC. We’ve traced these issues back to uncontrolled sources or inadequate process adjustments after a plant shutdown. It’s easy to gloss over these failures in a specification sheet, but the pain lands with people who depend on this compound for experiments, clinical trials, or high-value synthesis.

    Our approach replaces ambiguity with process data: every outgoing lot ships with batch COAs supported by real-time process logs, not just a photo of a test result. We maintain short feedback circuits with several recurring clients—when a batch gives unexpected results, we launch full process investigations, often sharing findings with the user and folding improvements into our next run.

    Distinction from Other Amines: More Than a Line in a Catalog

    Too often, lists of amine derivatives blend together. Yet the difference between 2-(1-Cyclohexenyl)Ethylamine and basic alkylamines sits upstream of any promissory TDS. Unlike linear amines or aromatic analogues, cyclohexenyl-based structures often deliver intermediate reactivity—reducing volatility concerns, raising stability, and allowing more predictable reactivity for routes needing controlled nucleophilicity.

    Take direct comparisons with n-butylamine or benzylamine: the cyclohexenyl backbone here supports more robust reaction conditions for processes making fused rings or bridging groups. Our R&D staff often field questions on this and advise on process tweaks such as base selection or solvent adjustments to get the most from the product’s cyclic backbone.

    In contrast, basic aliphatic amines swing toward higher volatility and handling hazards. Benzyl-substituted amines can show excessive side-reactivity in multi-step synthesis. Over a decade’s output demonstrates that for high-selectivity transformations, customers regularly stick with the cyclohexenyl-ethyl format to save time on purification and hit target yields in scale-ups.

    Challenges: Scaling, Supply Chain, and Regulatory Pressures

    Any factory operation faces daily tension between meeting ever-tighter specs and managing running costs. We watch regulatory changes around solvent emissions and handling requirements much like a lab follows an HPLC baseline—small moves ripple through the supply chain. Shifts in feedstock prices or logistics can eat margins if you haven’t locked in reliable, vetted sources. Laboratories upstream sometimes try alternate routes, chasing a cheaper per-kg rate. Enthusiasm can run out quickly after a few failed scale-ups or inconsistent NMR profiles.

    The right response lives in relentless attention to process discipline. We cross-train technicians so a new hire dozens of kilometers from the main site still executes the same reaction conditions, and we invest in analytical support to confirm compliance batch by batch. Plant shutdowns and re-starts—sometimes driven by local infrastructure changes—get handled using predefined restart protocols specifically developed from prior incident analyses. The knowledge embedded in these protocols means the same vessel runs clean product whether on the first kilo or the hundredth ton.

    Customer Collaboration: Factory Experience Meets End-User Needs

    Real value in specialty chemicals arrives through open dialogue with customers. When a client hits a purity snag or sees batch-to-batch drift in their application, our process team sits down and walks through recent logs. Sometimes it’s a subtle process change, a worn reactor gasket, or even an unnoticed atmospheric shift on a humid day. By hosting customers on site, we close feedback loops that allow for adjustments not just in process but in packaging, timeline planning, and logistics support.

    We learn as much from application feedback as from textbooks or journals. The insight that some end users experience yield swings during scale-up pushed us to revisit our catalyst charging procedures and drying steps. One research customer reported new peaks in gas chromatography after switching from drums to IBC totes. Our operations team ran side-by-side storage studies and found that shipping duration influenced trace impurity levels—a factory-level realization invisible in a typical trading office.

    Supporting Responsible Manufacturing and Product Stewardship

    Responsible manufacturing runs deeper than paperwork compliance. We integrate plant-level control systems for effluent treatment because we know that properly contained byproducts keep both the neighborhood and the next batch safe. We run everyday visual inspections of tank lines and containment areas—a single lapse can trigger contamination that takes weeks to resolve and costs more than routine vigilance.

    Our staff training covers not just handling and emergency steps, but also environmental responsibility. Waste minimization in the distillation area took shape after frontline operators flagged opportunities to recover more process solvent. By acting on these suggestions, annual solvent use dropped and fewer drums needed offsite treatment. These stories don’t make headlines, but they build a reputation that outlasts any single batch.

    Why Direct Manufacturer Relationships Matter

    Clients often share frustration when they’ve gone through too many intermediaries. When the source of 2-(1-Cyclohexenyl)Ethylamine isn’t clearly defined, troubleshooting problems extends into weeks or months. Our customers get to hear from actual line engineers and see real data from the same instruments that drive our internal quality decisions.

    We keep documentation clear—down to batch-specific spectral data, water content, and impurity profiles—because the more transparent we are, the easier it is for clients to plan their own downstream processes. This kind of direct line means that if a new regulatory requirement arises or a customer needs a process tweak, nobody is left guessing whether the supplier can actually deliver.

    Continuous Improvement Driven by Operational Data

    Making specialty chemicals involves a constant cycle of monitoring, learning, and adjusting. Small process data—such as the effect of feed pump speeds on batch color, or the role of nitrogen overlays during storage—has led to changes in how we operate that directly improve product quality and reliability. Even the loading technique when charging the reactor’s amination stage plays a role in impurity formation; we keep daily logs so that repeat mistakes get caught before they escape as off-batch product.

    Customer returns on questionable lots usually come with composition printouts and application background, giving us a chance to test new process controls in real time instead of relying only on theoretical models. We approach each report as a signal for process development, not merely a corrective chore. The result has been a consistently improving product that reflects years of applied experience rather than static, templated routines.

    Competitive Outlook and Future Product Development

    The chemical landscape doesn’t stand still. New synthetic targets, emerging fields in drug discovery, and more demanding environmental guidelines all shape what the next generation of 2-(1-Cyclohexenyl)Ethylamine production will look like. Instead of resting on legacy routines, we’ve invested in R&D partnerships and continuous training for the production crew—right down to equipment upgrades and enhanced process monitoring.

    Demand for more eco-friendly processes and tighter impurity control continues to grow. We’re piloting recovery units for spent catalysts and assessing bio-based raw materials, not just for the headline benefits but to keep our business resilient against raw material supply shocks. The push toward greener chemistry also opens the door to more energy-efficient synthesis routes that could both serve the environment and reduce unit costs.

    Insights From Day-to-Day Operations: Reliability in Every Batch

    Working on the plant floor, you learn quickly that chemicals like 2-(1-Cyclohexenyl)Ethylamine reward operational discipline and punish shortcuts. Success comes from a mix of standard operating procedures, pride in craft, and respect for the compound’s quirks. We set up redundant purity monitoring and ask our quality control team to cross-check results; missing a suspicious IR band or underestimating a faint odor often foreshadows issues for the next customer.

    Sharing these operational insights with partners boosts confidence. Some clients call directly during their own troubleshooting, seeking an unvarnished opinion about the process. These conversations often extend to advice on handling, safety, and disposal—practical support that a catalog listing never provides.

    Real-World Product Quality: Details That Outlast Any Brochure

    Spin a sample vial of 2-(1-Cyclohexenyl)Ethylamine under GC, and you learn quickly that every process step leaves its signature. From unexpected over-reduction byproducts to differences in amine content traced back to ammonia quench efficiency, real quality shows up in purity data, side-product profiles, and how the material feels and smells when poured from the drum.

    Most laboratories won’t see the subtle effects of drum linings, storage temperature, or even fill times unless they’ve hit production snags. Our process engineers constantly check for early warning signals, from shifts in batch color to the strange presence of a trace oxide peak in IR. The people making the product day in and day out know that quality isn’t static—it’s the sum of hundreds of choices made well before the finished drum leaves the plant.

    Customer-Led Adaptation: Customization That Starts at the Reactor

    Some projects need more than the typical purity standard. When a client approaches us to develop a slightly different isomer ratio or purity cut, we analyze their method goals and lab feedback. Adjustments at the reactor level—such as time, temperature, catalyst dosage—become real opportunities to co-develop innovations. Client feedback prompted us to develop tighter moisture specs for a subset of pharmaceutical buyers, and in response, we redesigned our post-reaction drying and nitrogen-purged packaging system.

    Building custom approaches relies on clear communication and a willingness to experiment safely within validated limits. We work alongside research teams during method development phases so new specifications reflect not just possibility but real, plant-level practicality.

    Building the Next Generation of Manufacturer-Client Trust

    Resilient, transparent sourcing grows out of hard-won relationships. End-users gain the most when they connect with the production reality behind their chemicals. Here, 2-(1-Cyclohexenyl)Ethylamine represents not just a chemical entity, but the final shape of process improvements, quality discipline, and a culture of technical engagement. Each drum we ship ties back to real work, feedback loops from the field, and the expertise of people who know every step from reactor charge to lab report.

    By opening our process to scrutiny and inviting input across the technology spectrum, we stay aligned with our customers’ evolving needs. Over time, this approach doesn’t just make for smoother supply; it anchors a partnership that bears out in new product launches, speedier troubleshooting, and new opportunities for both sides of the business. We know that the next solution may come from a customer’s question or a frontline worker’s suggestion—and that’s how we keep pushing forward with 2-(1-Cyclohexenyl)Ethylamine and every product that follows.