|
HS Code |
608719 |
| Iupac Name | 1H-Benzoimidazol-5-amine |
| Molecular Formula | C7H7N3 |
| Molar Mass | 133.15 g/mol |
| Cas Number | 5780-65-8 |
| Appearance | Off-white powder |
| Melting Point | 250-254 °C |
| Solubility In Water | Slightly soluble |
| Boiling Point | Decomposes before boiling |
| Density | 1.35 g/cm³ (estimated) |
| Smiles | c1cc2c(cc1N)nc[nH]2 |
As an accredited 1H-Benzoimidazol-5-Ylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle, 25g, with tamper-evident cap, hazard labeling, and chemical identification details. Sealed in a protective outer carton. |
| Shipping | 1H-Benzoimidazol-5-Ylamine is shipped in tightly sealed containers, protected from moisture and direct sunlight. It is handled as a laboratory chemical, requiring labeling according to safety standards. The package is cushioned to prevent breakage, transported under standard dry, ambient conditions, and accompanied by a Safety Data Sheet (SDS) for compliance and safe handling. |
| Storage | 1H-Benzoimidazol-5-ylamine should be stored in a tightly sealed container, placed in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and acids. Keep away from moisture and sources of ignition. Store at room temperature, protected from direct sunlight. Ensure proper labeling and restrict access to trained personnel to maintain safety and chemical stability. |
Applications of 1H-Benzoimidazol-5-Ylamine in Industrial ManufacturingAs a direct manufacturer of high-purity 1H-Benzoimidazol-5-Ylamine, we supply this specialty intermediate for distinct industrial sectors that require advanced formulation precision, rigorous quality control, and regulatory adherence. Below we outline real downstream application scenarios, providing practical details from industry standards to end-use integration based on proven production practices. 1. Pharmaceutical Active Ingredient Synthesis (API Development)Pharmaceutical manufacturers use 1H-Benzoimidazol-5-Ylamine as a building block for synthesizing benzimidazole-based APIs, including antifungal, antiviral, and antitumor drugs. This intermediate enters the heterocyclic ring formation process, enabling targeted molecular modification for efficacy and patent protection. Its controlled reactivity and purity are critical for reliable downstream coupling reactions and minimizing impurity profiles in complex API synthesis pathways. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Agricultural Fungicide FormulationAgrochemical producers employ 1H-Benzoimidazol-5-Ylamine in the synthesis of systemic and contact fungicides, such as benzimidazole derivatives for crop and seed protection. The material enters the nitrosation and further coupling stages, determining the spectrum of antifungal action. Its chemical consistency supports strict residue profiles and field efficacy, responding to regional MRL requirements and crop rotation programs. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Dye and Pigment Intermediate ManufacturingProducers of specialty dyes and pigments utilize 1H-Benzoimidazol-5-Ylamine as a key intermediate for synthesizing high-performance colorants, particularly yellow, orange, and red azo dyes used in plastics, textiles, and ink applications. The amine group enables controlled diazotization and coupling reactions, ensuring fastness and purity tailored to downstream substrate compatibility and regulatory colorant traceability. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Electronic and Performance Polymer SynthesisProducers of advanced polymers for electronics and specialty films depend on 1H-Benzoimidazol-5-Ylamine to introduce benzimidazole moieties, which enhance thermal stability, flame retardancy, and dielectric properties. The material reacts during prepolymer condensation or as a chain extender, precisely controlling polymer structure and functionality in high-performance applications such as flexible printed circuits, high-frequency insulation, and specialty fiber-reinforced composites. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Corrosion Inhibitor Additive for Water Treatment ChemicalsWater treatment chemical manufacturers incorporate 1H-Benzoimidazol-5-Ylamine as an organic corrosion inhibitor precursor for closed-loop and industrial cooling water systems. Its amine structure forms protective complexes with metal surfaces via adsorption in formulated inhibitor blends, extending equipment service life while meeting environmental discharge limits. Dosage and integration depend on the chemistry of the water system and compatibility with other scale and biocide packages. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
|
Competitive 1H-Benzoimidazol-5-Ylamine prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: admin@sinochem-nanjing.com
Flexible payment, competitive price, premium service - Inquire now!
In our daily operations as a chemical manufacturer, decisions about what goes into a reaction vessel come down to much more than numbers and labels; reliability, traceability, and batch-to-batch consistency matter just as much. Among the specialty intermediates we routinely produce, 1H-Benzoimidazol-5-Ylamine holds a central position for customers in pharmaceuticals, agricultural synthesis, and advanced materials. Instead of speaking in abstracts, experience has shown the difference a dedicated manufacturer can make compared to rebranded or blended alternatives.
From the earliest trial batches to today’s scalable production, our team has handled many kilograms of this key benzimidazole derivative. Each lot brings its own challenges — humidity, raw material quality, and subtle adjustments to the process can all affect outcome. The result: we have learned to fine-tune every step, tracking the tiniest signs — color by eye, response to TLC, even the way the product handles when scooped into a flask.
We never expected the market for 1H-Benzoimidazol-5-Ylamine to grow this quickly when we first developed our in-house route. Earlier, commercial supply sources showed detours through resellers or gray-market vendors. To avoid this, our decision was to produce 1H-Benzoimidazol-5-Ylamine from scratch, using high-grade starting materials, monitored synthesis, and direct purification without shortcuts. Feedback from developers in pharmaceutical research and fine chemical synthesis provides proof of our consistent quality, whether a customer requests grams or multi-kilo lots.
We supply multiple grades — from R&D samples to higher-purity process intermediates for pilot scale production. Each batch undergoes a defined array of tests, including NMR verification, GC and HPLC purity checks, and a visual inspection for trace color differences or particulate matter. This may sound like overkill, but deviations become glaringly obvious in downstream coupling reactions — a lesson that comes only after bottles of unknown origin disrupt an entire preparation.
Some market sources disperse impure, grey-toned “benzoimidazole amines” under several synonyms. These sources may not control raw material origins or minimize exposure to air and moisture during packaging. Such uncontrolled minor variations can cause missed yields, off-flavors (noticeable in finished actives for agrochemicals), and false-positive chemical tests. Our internal controls prevent this by sealing product in inert atmospheres, maintaining batch traceability, and shipping well within shelf-life. Years of feedback from process chemists — not simply online orders — direct every change we make.
Some colleagues in research and development ask only for a nominal assay or a copy of a specification sheet. We share those, but more importantly, we guarantee full transparency on process disclosures and analytical results. Standard batches test at 98% or higher assay by HPLC, with water content below 0.5%. A major benefit: our in-house analytical lab allows for tailored runs, so requests for extra-dry (low ppm water content), UV-absorbance characteristics, or color testing can be fulfilled quickly. Individual vials and drums show specification deviations — never simply “pass/fail” marks — and batch samples are kept in long-term storage for warranty, re-tests, or regulatory questions.
Particle size and flow might sound like an afterthought for a benzimidazole derivative, but those handling larger amounts recognize where they matter most — not during bottle sampling, but at the kilo scale, where plug flow in reactors or hopper bridging can disrupt hours of work. By adjusting our crystallization and milling methods, we achieve a consistently free-flowing powder with no agglomerates; this can reduce electrostatic clumping and mechanical blockages in pilot and semi-commercial plants.
Often, project chemists approach us after failed reactions using off-patent substitutes or lower-purity imports. A common problem: unidentified byproducts that pop up in side reactions, especially during sulfonation or cross-coupling steps. Because our product comes documented with full structure confirmation, and our technical staff know exactly which minor signals to watch for in NMR or MS, users avoid these unpleasant last-minute surprises. Even minute color contaminants, too small to register on a typical certificate of analysis, are flagged and traced by our lab before a single lot leaves the facility.
As demand for benzimidazole intermediates grows in fields like pharmaceutical API synthesis and crop protection agent development, we have worked closely with end-users to support scale-up. Researchers often underestimate how a small molecule’s origin and performance in laboratory settings can diverge dramatically from what occurs in a full-scale reactor. In our experience, only certified, consistently manufactured 1H-Benzoimidazol-5-Ylamine allows developers to replicate small-batch results at production scale. The same applies for life science projects, where even tiny impurity peaks can trigger regulatory investigations or force costly re-qualification at a late development stage.
Manufacturers who partner with us often request both technical involvement and shipment flexibility. We provide both: our scale-up team is on hand for process troubleshooting, and regular feedback cycles with users inform our batch production, packaging protocols, and change notifications. Because we operate under open, E-E-A-T-driven principles, every customer gets access to real batch data, not just generic "lot conforms" one-liners. Our regular clients know they can rely on the authenticity of our documentation when submitting to international authorities or process auditors; the same batch numbers and original records track product from plant to end-user, not just through a paper trail.
During a recent audit of industry competitors, we examined several marketplace samples labeled as 1H-Benzoimidazol-5-Ylamine. Most came from external resellers, relabelers, and non-transparent suppliers. Few could provide full documentation of raw material origin, synthetic pathway, or compliance with heavy metal limits. In contrast, our manufacturing chain is fully vertical, from ordering reagents to final packaged material, with every reaction and purification step logged in digital batch records and available for review.
Some generic sources cut costs by skipping careful recrystallization or by reblending off-spec intermediates. This can lower price, but our feedback from users paints a clear picture: final products from these sources often suffer poor shelf-life, unexpected solubility issues, or unexplained performance changes. In process-intensive industries, this bargain often ends up costing more through repeated QC testing or failed downstream syntheses. Our choice to avoid compromised raw material or purification flows is based on practical experience — our own batch logs and customer returns tell the story better than any marketing slogan.
For customers involved in regulatory submissions, such as pharmaceutical companies or agrochemical formulators, product traceability and batch integrity aren’t optional. Our facility maintains full GMP-like records and trace batch samples for up to seven years, so questions about trace contaminants or unexpected peaks in finished products are answered quickly, with real samples for analysis. Direct manufacturer traceability stands out starkly in global supply chains, where even seasoned buyers have reported “mystery batches” from third-party suppliers with missing documentation.
The range of applications for 1H-Benzoimidazol-5-Ylamine is constantly evolving. In the pharmaceutical sector, researchers use it as a core intermediate for anti-infective agents and enzyme inhibitors. Crop science laboratories employ it in herbicidal and fungicidal molecule discovery. Material scientists utilize its aromatic backbone as a building block for specialty polymers and advanced colorants. Our close contact with leading R&D groups gives us a front-row seat to changing demands — tighter impurity controls, new derivative requests, and the need for more sustainable processes.
By being involved from synthesis through shipping, including technical troubleshooting and rapid batch adjustment, we enable both established manufacturers and startups to focus on innovation instead of QC firefighting. Over the past decade, as project goals in both pharma and specialty chemicals have become more ambitious, our model of manufacturer-direct communication proves key; we share real process limitations and improvement options, aiming at results, not empty marketing promises.
We offer technical support throughout the project development life-cycle: pre-purchase evaluation, joint testing in new routes, pilot-scale lot customizations on request, and after-sales trouble-shooting. This hands-on involvement isn’t for the accolades; it’s because every variation, every process change, feeds back into our own process improvement. In making adjustments to crystal form, particle distribution, or even drying protocols, we have incorporated direct feedback from users who ran into blockages, color drift in sensitive formulations, or storage issues caused by atmospheric moisture. Few distributors or resellers can match this level of technical engagement; they simply don’t have access to batch-by-batch process records or the laboratory infrastructure required to quickly run a troubleshooting analysis.
In our decades on the production floor, short cuts have never paid off. Careless process tweaks or acceptance of subpar raw material almost always return as technical headaches or warranty claims — sometimes years later. Our approach: strict adherence to reproducible synthesis protocols, direct shipment from plant, and refusal to blend off-spec material into finished lots. Because we deal directly with those who use the product day-in, day-out, any defect is immediately apparent — most often by the third or fourth analytical run.
Product purity remains central, but we realize modern users require more than just a high assay. Packaging integrity, accurate shelf-life forecasting, and robust traceability systems make practical differences in project outcomes. Simple but critical packaging measures — such as double-layered aluminum bags for low-level moisture control, or tamper-evident drums — emerged only after years of root-cause investigations into batch degradation and transport damage. Customers in humid or remote regions report that such “minor” details spared hours of troubleshooting and avoided waste disposal headaches.
Long experience tells us not to chase market fads or fake demand signals. For every genuine spike in need — such as during COVID-driven increases in active ingredient synthesis — we received a surge of requests for high-purity 1H-Benzoimidazol-5-Ylamine. We met these with expanded internal production, not by sourcing unknown-packed bags from faceless vendors. The result: zero recall events, no unexplained impurities, and uninterrupted support for urgent applications in drug intermediates and crop protection.
Stakeholders across the chemical value chain increasingly ask tough questions about process consistency, environmental impact, and downstream stability. While abstract discussions dominate conferences, practical solutions emerge on the floor of the manufacturing plant. We haven’t shied away from customer-initiated audits, process reviews, or blind-sample challenge runs. Across many years, raw data — crystalline structure, documented shelf-life under real-world shipping, and recovery from thermal cycling — has taken precedence over generic assurances.
Our operational feedback loop between end-user, technical team, and production is real, not theoretical. Batch failures or contamination events become opportunities for permanent process correction. Back in the early 2010s, our control systems flagged a recurring source of particulate contamination in dried batches; the root cause was a dust-prone valving mechanism. Design changes, regular deep-clean protocols, and container upgrades solved this for good, and we share the details of these changes openly with our professional partners. Honesty is our best tool for long-term business, as many project failures stem from untraceable sources and “black-box” blends common on open markets.
Our experience traces a straight line from fully transparent manufacturing to improved outcomes, lower rework rates, and reduced regulatory hassle for downstream users. Large multinational firms and small specialty labs alike increasingly expect detailed supply chain documentation, not just product shipped to a price point. Each drum, vial, or bag leaving our facility carries a tamper-proof batch seal, and shipment manifests include authentic, batch-specific certificates signed by in-house chemists, not faceless “compliance departments” or resellers with minimal laboratory presence.
Supply chain turbulence in recent years — especially shipping bottlenecks, raw material shortages, and shifts in global chemical logistics — have created risk of counterfeit and unreliable material. The lesson: it’s worth insisting on original manufacturer-sourced 1H-Benzoimidazol-5-Ylamine. No technical operation, whether a pilot plant, analytical lab, or regulatory submission effort, can recover the time lost to contamination events or documentation discrepancies caused by repackaged or generic material. We have stood firm against blending or outsourcing our product, choosing instead to build capacity and maintain staff training for even small or urgent batch jobs.
From conversation with our customers, we know the choice to buy from a direct manufacturer is rarely about price alone. Technical support, immediate problem-solving, and access to original analytical data win out long-term. Our track record over the last decade stands as proof: repeat orders and project renewals come from companies that value process transparency, deep technical knowledge, and quick response to specific application questions.
With rapid advances in drug design, life sciences, and specialty materials, it is easy to fall behind if a producer cuts corners, outsources key processes, or provides incomplete records. Our strategy is simple — keep the full scope of manufacturing, analytical verification, packaging, and technical service inside the organization. This gives us direct accountability for each ton, each kilogram, each batch of 1H-Benzoimidazol-5-Ylamine that leaves the site. Data integrity, technical know-how, and a feedback-driven improvement cycle aren’t just regulatory requirements; they keep chemical industries moving forward, even in turbulent times.
Many challenges remain, including adapting synthesis to improve yield, minimize waste, and address changing regulatory codes. Our ongoing work in process development, investment in cleaner, safer filtration and drying technology, and attention to minor improvements — such as packaging upgrades and even simple user instructions — push our product in the only direction that matters: forward.
Every kilogram of 1H-Benzoimidazol-5-Ylamine reflects decades of accumulated process improvements and hard-won insight. We share more than a product — we provide a partnership for progress, anchored in technical reliability and an open-window approach to every step of manufacturing and support. That is how we meet demand: not with slogans, but with the lasting value only a dedicated manufacturer can deliver.