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10-Undecyn-1-ol

    • Product Name 10-Undecyn-1-ol
    • Alias 10-Undecynol
    • Einecs 225-201-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    659737

    Cas Number 66144-49-6
    Molecular Formula C11H20O
    Molecular Weight 168.28 g/mol
    Iupac Name undec-10-yn-1-ol
    Appearance Colorless to pale yellow liquid
    Boiling Point 284-286°C (estimated)
    Density 0.87 g/cm³ (approximate)
    Melting Point -20°C (estimated)
    Solubility In Water Insoluble
    Functional Groups Alkyne, alcohol

    As an accredited 10-Undecyn-1-ol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 mL amber glass bottle with PTFE-lined cap, labeled “10-Undecyn-1-ol,” includes hazard symbols, CAS number, and handling instructions.
    Shipping 10-Undecyn-1-ol is shipped in tightly sealed containers, protected from light, moisture, and sources of ignition. It should be handled according to local and international regulations for flammable and hazardous chemicals. Proper labeling, secure packaging, and documentation ensure safe transport. Use of appropriate personal protective equipment is recommended during handling and shipping.
    Storage 10-Undecyn-1-ol should be stored in a tightly sealed container, away from direct sunlight, heat sources, and incompatible substances such as strong oxidizers. Store in a cool, dry, and well-ventilated area to prevent moisture absorption and degradation. Label the container clearly and keep it away from ignition sources, as it may be flammable. Ensure appropriate spill containment measures are in place.
    Application of 10-Undecyn-1-ol

    Applications of 10-Undecyn-1-ol in Industrial Manufacturing

    10-Undecyn-1-ol serves as a vital specialty raw material in several focused industrial segments. Its unique terminal alkyne and primary alcohol functionality support various targeted chemical transformations. We summarize key downstream manufacturing applications, with technical details relevant for process engineers, formulation chemists, and industrial buyers.

    1. Pharmaceutical Intermediates for Active Pharmaceutical Ingredients (API) Synthesis

    Our customers use 10-Undecyn-1-ol as a building block in synthesis routes for specialty pharmaceutical intermediates, particularly for APIs involving modified aliphatic chains with terminal functionality. It acts as a starting point in Sonogashira coupling, nucleophilic substitution, and selective hydrogenation steps, enabling tight control over chain extension or functional group transformations. Integration at the intermediate stage ensures that our material meets strict impurity specifications and supports batch-to-batch reproducibility in regulated environments.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • 21 CFR Part 211: US FDA cGMP for finished pharmaceuticals
    • EU EudraLex Volume 4: GMP Guidelines
    • USP-NF General Chapters for impurity profiles of raw materials

    Typical usage ratio

    • 0.9–1.2 molar equivalents in core synthetic routes, adjusted for process yield and side reaction minimization

    Downstream process integration

    • Introduced during chain-functionalization reactions or in terminal coupling after core ring construction
    • Frequently handled under inert conditions and incorporated via precision batch dosing to reactor trains

    Final product types

    • Small molecule APIs with extended aliphatic side chains
    • Intermediates for prodrugs and specialty pharmaceuticals
    • Chiral alcohol derivatives for enantioselective synthesis

    2. Cosmetic and Personal Care Active Ingredient Synthesis

    Cosmetic ingredient manufacturers source 10-Undecyn-1-ol for its use as a precursor in the synthesis of functionalized surfactants, skin-conditioning agents, and chain-extended emollients. The terminal alkyne group enables downstream functionalization and attachment of hydrophilic or hydrophobic modifiers, resulting in unique performance properties such as mildness and targeted deposition. Full traceability and compliance with cosmetic safety standards enable direct use in personal care intermediate manufacturing.

    Industry compliance standards

    • ISO 22716: Cosmetics – Good Manufacturing Practices (GMP)
    • EU Regulation (EC) No 1223/2009 on cosmetic products
    • Cosmetic Ingredient Review (CIR) safety guidelines
    • REACH Registration for ingredient traceability

    Typical usage ratio

    • 1–8% weight/weight in specialty emulsifier synthesis, subject to batch size and target HLB levels

    Downstream process integration

    • Charged at esterification or etherification unit operation for conversion to performance additives
    • Used in post-synthesis purification to ensure defined carbon chain distribution

    Final product types

    • Cosmetic surfactants for mild cleansing formulas
    • Skin-conditioning alcohol ethers
    • Emollient intermediates for creams and lotions

    3. Polyethylene Glycol (PEG) Derivative Production

    Producers of specialty PEG derivatives and nonionic surfactants incorporate 10-Undecyn-1-ol as an alcohol initiator in ethoxylation reactions. The terminal alkyne function introduces anchoring sites for further click-chemistry modifications, expanding the utility of finished PEG chains for industrial emulsification or dispersion additives. Controlled addition at the start of the polymerization allows consistent molecular weight distribution and tailored polymer end-capping.

    Industry compliance standards

    • ISO 9001 Quality Management for chemical intermediates
    • OECD Guidelines for Testing of Chemicals
    • Relevant local environmental authority discharge regulations (for reaction byproducts)
    • Food Contact notification if PEG derivatives intended for indirect food contact applications

    Typical usage ratio

    • 0.2–2.5% of total charge weight in ethoxylation reactor, customized to target PEG chain length (n=5-100)

    Downstream process integration

    • Dispensed as initiator prior to ethylene oxide feed in continuous or semi-batch reactors
    • May require vacuum drying to ensure low water content for EO safety

    Final product types

    • PEG ethers with terminal alkyne
    • Custom surfactant intermediates for paints, inks, and textile auxiliaries
    • Reactive PEG-macromers for polymer modification

    4. Agrochemical Intermediate Synthesis

    Manufacturers in the agrochemical sector leverage 10-Undecyn-1-ol for preparation of specific chain-extended intermediates used in herbicide and pesticide formulation. Its defined carbon chain and functional group placement allow precise molecular modifications through substitution, esterification, or oxidation reactions. Batch traceability, compliance with pre-registered agrochemical standards, and a validated impurity profile support finished product safety requirements.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • ISO 17025 for testing and calibration laboratories (analytical support for impurities)
    • REACH and CLP Regulation for chemical registration and hazard classification
    • Globally Harmonized System (GHS) for labeling of downstream products

    Typical usage ratio

    • 3–5% by total batch mass in intermediate production, adjusted depending on downstream coupling reaction efficiency

    Downstream process integration

    • Prescribed as substrate for chain extension during nucleophilic addition or oxidation steps in technical plant protection ingredient synthesis
    • Generally utilized in closed reactor systems with monitoring for volatile alkyne loss

    Final product types

    • Herbicide and pesticide intermediates with functionalized alkyl chains
    • Plant growth regulator precursors
    • Adjuvant raw materials for agrochemical formulations

    5. Electronic Chemicals and Functional Materials

    Manufacturers of high-value specialty materials select 10-Undecyn-1-ol to introduce chain-length-controlled alkyne alcohol moieties into the synthesis of polymerizable monomers, electronic photoresists, and functional coating precursors. The defined structure supports precision molecule design, particularly in photolithography and electronics assembly processes where end-group functionality dictates performance. Manufacturing handles this intermediate under controlled humidity to avoid side reactions in downstream high-purity applications.

    Industry compliance standards

    • SEMI C93 Semiconductor Standards for chemical purity
    • IECQ QC 080000: Hazardous Substance Process Management System
    • ISO 14001: Environmental Management for chemical processing plants
    • Customer-specific purity and trace metal specifications under NDA

    Typical usage ratio

    • 0.5–3.0% by total monomer feed weight, depending on desired polymer backbone modification or end-capping

    Downstream process integration

    • Dosed at polymerization onset in closed, atmosphere-controlled equipment
    • Subjected to in-process QC for moisture and PM trace analysis

    Final product types

    • Alkyne-functionalized acrylic monomers
    • Photoresist precursors for advanced microelectronic patterning
    • Functional coatings for semiconductor and display panel assembly
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    Certification & Compliance
    More Introduction

    Introducing 10-Undecyn-1-ol: Experience From the Manufacturer’s Bench

    After years in the lab and on the production line, I still remember the buzz in our facility when we developed a practical route for 10-Undecyn-1-ol. Bringing this specialty alkyne-alcohol to commercial scale was no small feat, but the results quickly proved the struggle worthwhile. In our sector, the difference between a good intermediate and an essential building block often comes down to molecular quirks and what they offer synthetic chemists, material scientists, and fragrance innovators. 10-Undecyn-1-ol delivers on every count, and most of that has to do with the rare pattern of functionality in its structure.

    Model and Specifications

    We produce 10-Undecyn-1-ol with careful attention to purity and reproducibility. Through direct experience managing reactors day and night, I’ve handled batches from grams to hundreds of kilos. The molecular structure, featuring both a terminal alkyne and a primary alcohol at opposite ends of an 11-carbon chain, opens doors that shorter analogues simply can’t. During synthesis, controlling contaminants—especially alkyne hydration and over-reduction byproducts—became the challenge that shaped our real-world expertise. Every batch we release holds to tight criteria for water content, residual solvents, and trace metals. Regular users notice that high-purity lots run longer in catalysts, cut down on purification headaches, and deliver better yields in downstream chemistry—a direct result of lessons learned on our line.

    Usage in the Real World

    If you spend time on pilot lines for new polymers, or if you piece together custom fragrances for fine-tuned sensorial qualities, you might recognize the value in selective reactivity. In our own R&D, 10-Undecyn-1-ol turned out to be a surprisingly versatile starting point. Its terminal alkyne plays well in click chemistry and azide-alkyne cycloaddition reactions, often outpacing similar-length alkynes lacking a free alcohol. In our own experience, the long chain formation nicely balances hydrophilic and hydrophobic worlds, allowing the alcohol head and terminal carbon–carbon triple bond to serve as handles for further derivatization.

    From the manufacturing floor, I’ve worked closely with formulators who develop novel lubricants, surfactants, and specialty polymers. Several have told me they choose 10-Undecyn-1-ol because it enables unique surface binding and cross-linking. Our technical partners in the lab have shown how small changes in the backbone—one extra carbon, swapping the triple bond position—can derail target product properties. The subtle length of the chain and spacing between the alcohol and alkyne deliver a flexibility few similar chemicals offer, especially in rigid molecular frameworks for advanced materials and coatings.

    Why Chain Length and Functionality Matter

    Having spent time running both batch and continuous processes for specialty alcohols, I’ve seen chain length make or break a project. Shorter terminal alkynols, like 6-hexyne-1-ol, often present high volatility and lower compatibility in hydrophobic environments. Longer analogs, with chains past C13 or C15, quickly become waxy or lose solubility in the media most customers target. We put 10-Undecyn-1-ol right in the sweet spot, balancing processability and functional group reactivity.

    Some synthetic chemists only realize the nuance after repeated reaction runs: the presence of the triple bond on the terminal end allows for controlled click reactions, Sonogashira couplings, and even subtle functional group interconversions that lead to heterocycles or new analogues in pharmaceutical development. The primary alcohol can anchor the molecule onto surfaces, or serve as a launching pad for additional modifications such as esterification or oxidation. Walking customers through these options in our application support work has uncovered routes to functional coatings and active pharmaceutical intermediates that would be hard to realize with more common alcohols or alkynes.

    Consistency and Scale Matter to Real Manufacturers

    Maintaining batch-to-batch consistency stands at the core of our operation. Building up from the kilo scale, we discovered that tiny shifts in catalyst quality, solvent ratios, or even order of addition result in major outcome differences. Over-production of byproducts becomes a real risk as vessels scale up, especially when catalyst life varies from lot to lot. Staff training, periodic equipment calibration, and a relentless focus on in-line analytical monitoring underlie each shipment that leaves our plant. The end result pays off for users who require the certainty that a liquid alkyne with 98% or better purity will actually deliver what the certificate says. Over years of supplying this material, we've seen that successful customers in R&D and production both depend on trust and transparent communication about process changes, impurity profiles, and real-word performance.

    Comparing with Other Products

    You notice 10-Undecyn-1-ol’s advantage most clearly when you line it up against saturated alcohols or shorter-chain alkyne derivatives. Saturated alcohols like 1-decanol, despite similar chain lengths, can’t match the alkyne’s ability for click chemistry or serve as a backbone for functional polymer labels. The absence of a triple bond makes most ordinary alcohols non-starters for linking technology. If the need calls for unique reactivity, the differences become clearer as soon as a synthesis route demands regioselectivity or orthogonal functionalization.

    Short-chain alkynols can provide selectivity in some pharma applications, but volatility, odor, and limited solubility push many users to seek out longer chains. 10-Undecyn-1-ol fills that gap for those working with specialty elastomers, high-value coatings, or surfactant-like architectures with a functional twist. In fragrance and flavor development, our technical collaborations showed us that the molecular backbone and functionalization points actually contribute a clean, linear presence in complex blends, often minimizing undesirable notes associated with shorter or branched counterparts.

    Some newer entrants to the market produce similar-length alkynols by different means. We’ve spent years tuning our synthesis—selecting each step for both efficiency and sustainability. Our direct alkyne introduction route avoids unnecessary waste and reduces reliance on precious metal catalysts. This not only delivers a lower eco footprint but has made our long-term partners more confident when regulatory review comes around.

    Applications We’ve Helped Develop

    Through collaborations, we’ve contributed to innovations beyond standard catalogs. Our molecule found its way into functional nano-coatings and high-end medical adhesives. During a project with a polymer additive start-up, they discovered that the positioning of the alkyne on the end of a long, flexible chain allowed for rapid post-polymerization crosslinking. The resulting materials demonstrated superior durability and altered surface tension, a need in the ever-growing market for smart surfaces and medical devices.

    Working with specialty fragrance manufacturers, our team supported the creation of long-lasting aroma fixatives. The balanced volatility profile of 10-Undecyn-1-ol lets it act as a carrier for delicate esters, extending shelf life without introducing fatty, off-notes commonly found with similar chain alcohols. In personal care applications, surfactants based on this compound showed enhanced wetting and lower critical micelle concentrations than traditional lauryl or cetyl alcohol-based products.

    On the pharmaceutical front, several research groups asked for help scaling up click conjugation reactions with demanding purity requirements. After months of joint troubleshooting, we tweaked our purification strategy, reducing nonvolatile residue and boosting final product yields for both process development and clinical trial materials. One interesting use occurred during the development of a photo-crosslinked hydrogel for drug delivery, where the dual-functionality allowed for precise polymer architecture and targeted functionalization.

    Technical Support That Grows With the Market

    Real-world technical support doesn’t end with a quick answer to an email. Over time, we’ve personally visited pilot plants and research labs to resolve scale-up issues. Some customers faced challenges in dissolving 10-Undecyn-1-ol into complex monomer blends, especially due to the unique surface tension and partial miscibility with traditional solvents. We worked on the floor to optimize mixing protocols, adjust heating programs, and recommend supplementary co-solvents. Saving a batch from a failed addition or incomplete conversion means understanding the practical wrinkles that crop up outside the idealized lab environment.

    Polishing quality doesn’t happen in a vacuum. We constantly monitor customer feedback as part of our operations review. If a user struggles with odor contamination or crystallization, our process engineers review the corresponding run history, refine our purification stages, and select the right storage and packaging conditions to balance both reactivity and shelf-life. With regulatory agencies turning up the heat on chemical provenance and low-residual content for advanced materials, our built-in traceability system documents every step from raw materials to shipment, reassuring both new and established partners.

    Continuous Improvement: Eco and Safety Concerns

    Chemical manufacturers have a duty to both their customers and the environment. Early on, we moved away from solvents that showed persistent safety or waste problems. During scale-up, shifting from classical Grignard or high-copper routes to greener processes both improved our yields and cut down on hazardous waste. Investing in closed-loop solvent recovery paid off in lower emissions and a safer work floor. We learned that listening to both operators and customers leads to smarter changes—not just meeting existing regulations, but anticipating where the industry must go.

    Storage and shipping also present real challenges for an alcohol with moderate volatility and specific storage requirements. Drummers and warehouse staff noted condensation and handling issues, especially under humid or rapidly changing temperatures. We redesigned our shipping containers and invested in packaging that maintains low water content and prevents oxidative degradation throughout normal shipping times. This practical focus on usability means most customers open a drum or bottle and find a clear, ready-to-use liquid—no extra drying or purification steps required, and a significantly reduced risk of lost batches from off-spec quality.

    Building Direct Relationships With End-Users

    Having worked face-to-face with the people who use our chemical in manufacturing and research, I know the value of feedback. It’s easy enough for a trader or middleman to move a drum of material from warehouse to warehouse, but real knowledge comes from handling, processing, and improving the product on-site. Customers in advanced materials, specialty coatings, and custom synthesis often require tight timelines and responsive supply. We maintain a direct technical line to project leads and procurement specialists, so needs get addressed fast, not lost in translation or bureaucracy.

    It’s not just about shipping product—it’s about keeping the lines running and projects on schedule. With global sourcing headaches growing, our domestic production lines and stable raw material contracts keep our customers insulated from the worst of price swings and shortages. We see it as a point of pride that our partners reach out to us for more than just a quote. When supply chain interruptions hit, our technical and production teams stretch to reprioritize production slots and keep research, pilot, and production lines moving.

    Real-World Innovations Rely on Solid Building Blocks

    The history of synthetic chemistry proves one thing: advances in drugs, materials, flavors, and coatings often trace back to designers who spotted the subtle value in an unusual building block. 10-Undecyn-1-ol has carved out a place on the lab benches of material scientists, pharma chemists, and product developers not by accident, but through lived experience. It opened possibilities in surface modification, click chemistry, and even responsive materials, which saturated or shorter analogues simply could not match.

    We see our role as more than just a supplier. We are collaborators, problem-solvers, and, frankly, troubleshooters. Over the years, optimization of every step—from raw material acquisition to shipping logistics—has come with its challenges and lessons. When customers run into unexpected roadblocks, we share what we’ve learned: tips for dilution, strategies for filtration, and, when necessary, suggestions for alternate derivatives. That continuous feedback loop means product quality grows over time, and that users can rely on a product whose performance evolves to meet ever-changing demands.

    What We’ve Learned and Where We’re Headed

    With every order shipped and every technical problem solved, our experience producing and supplying 10-Undecyn-1-ol deepens. The unique chemistry—terminal alkyne paired with a primary alcohol on an undecyl backbone—offers a combination of flexibility, processability, and targeted reactivity. Material scientists depend on the reactivity profile and adaptability, fragrance creators find value in its sensory profile, and coating developers tap its role in cross-linking and modification.

    As regulatory scrutiny intensifies and the market pushes for greener, safer chemicals, our investment in efficient process design, waste reduction, and direct application support becomes ever more crucial. Projects that once required months of troubleshooting now benefit from a fast, experienced response from a manufacturer who has walked the same production floors and solved the same bench-scale headaches.

    10-Undecyn-1-ol stands as a testament to what targeted molecular design, careful process control, and real-world collaboration can achieve. Our journey—from the early lab-scale reactions prone to failure, to the modern, highly controlled production processes—mirrors the progress of the industries we support. Users receive more than a chemical; they gain the collective experience and work ethic of a dedicated manufacturer committed to their success.