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1-Propyl-3-Methylimidazolium Acetate

    • Product Name 1-Propyl-3-Methylimidazolium Acetate
    • Alias [PMIM][Ac]
    • Einecs 809-997-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    320435

    Chemical Name 1-Propyl-3-Methylimidazolium Acetate
    Cas Number 144949-75-5
    Molecular Formula C9H16N2O2
    Molar Mass 184.24 g/mol
    Appearance Colorless to pale yellow liquid
    Density 1.09 g/cm3 (at 25°C)
    Melting Point -55°C (approx.)
    Boiling Point Decomposes before boiling
    Solubility In Water Miscible
    Ph Neutral to slightly basic
    Odor Slight, vinegar-like

    As an accredited 1-Propyl-3-Methylimidazolium Acetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1-Propyl-3-Methylimidazolium Acetate supplied in a sealed, amber glass bottle with hazard labeling and tamper-evident cap.
    Shipping **Shipping Description:** 1-Propyl-3-Methylimidazolium Acetate is shipped in tightly sealed, chemical-resistant containers, ensuring protection from moisture and air. Containers are clearly labeled and cushioned within sturdy cartons. The package complies with international transport regulations and is accompanied by appropriate safety documentation (SDS). Store and ship at ambient temperature, away from incompatible materials.
    Storage 1-Propyl-3-Methylimidazolium Acetate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from moisture and direct sunlight. Keep away from incompatible materials such as strong oxidizers or acids. Ensure proper labeling and avoid sources of ignition. Use appropriate personal protective equipment (PPE) when handling and store according to local chemical safety regulations.
    Application of 1-Propyl-3-Methylimidazolium Acetate

    Applications of 1-Propyl-3-Methylimidazolium Acetate in Industrial Manufacturing

    As the direct manufacturer of 1-Propyl-3-Methylimidazolium Acetate (PMIAc), we supply this ionic liquid to specialized industrial users who require consistent performance in demanding chemical processes. PMIAc demonstrates value in several established downstream sectors, where its unique physicochemical characteristics support innovative and established production techniques. Below is an overview of practical B2B application scenarios, based on real-world manufacturing requirements.

    1. Cellulosic Biomass Dissolution for Advanced Cellulose Material Production

    Commercial cellulose processors employ PMIAc as a high-efficiency solvent for dissolving cellulose feedstocks, enabling the production of regenerated fibers, films, and membranes. By leveraging PMIAc’s strong hydrogen bond basicity, manufacturers streamline the dissolution of wood pulp and agricultural residues without the need for extensive pre-derivatization or harsh chemical treatments. This approach supports environmentally responsible material manufacturing with precise control over solution viscosity and chain length integrity.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • OEKO-TEX® Standard 100 for textile input chemicals
    • EU REACH Regulation (EC) No 1907/2006 compliance for substance registration
    • ZDHC Manufacturing Restricted Substances List (MRSL) for sustainable textiles

    Typical usage ratio

    • Cellulose loading in PMIAc typically ranges from 2% to 10% w/w, based on desired product viscosity and fiber morphology.

    Downstream process integration

    • PMIAc enters directly into the dissolution vessel, mixing with pre-treated cellulose at 80–120°C until homogeneous solution formation. Solution is then processed into fibers or films via spinning or casting and subsequent anti-solvent precipitation.

    Final product types

    • Lyocell fibers for textile manufacturing
    • Regenerated cellulose membranes for filtration
    • Cellulosic films for packaging and specialty applications
    • High-performance specialty yarns

    2. Homogeneous Catalysis System for Organic Synthesis

    Synthetic chemical manufacturers utilize PMIAc as a green reaction medium in homogeneous catalysis, especially for alkylation, acylation, and cross-coupling reactions. Its ionic nature stabilizes both transition metal catalysts and reaction intermediates, enhancing substrate solubility and enabling high selectivity at moderate operational temperatures. PMIAc’s negligible volatility aids in minimizing solvent losses and fugitive emissions, supporting regulatory compliance and process safety.

    Industry compliance standards

    • GMP ICH Q7 guidelines for active pharmaceutical ingredient (API) process solvents
    • ISO 14001:2015 Environmental Management Systems
    • US EPA’s Toxic Substances Control Act (TSCA) for solvent use
    • EU ECHA SVHC list monitoring for new solvent introductions

    Typical usage ratio

    • Solvent volume typically equals substrate weight (1:1 to 3:1 solvent:substrate ratio), adjusted by catalyst solubility and target yield requirements.

    Downstream process integration

    • PMIAc is charged into the reaction reactor alongside catalysts and substrates; post-reaction, product isolation uses anti-solvent extraction or crystallization, allowing ionic liquid recycling.

    Final product types

    • Fine chemicals and API intermediates
    • Pharmaceutical building blocks
    • Specialty organic dyes
    • Agrochemical synthesis intermediates

    3. Electrolyte Component for High-Performance Battery Development

    Manufacturers of next-generation energy storage devices integrate PMIAc as part of the liquid-phase electrolyte mixture in lithium and sodium ion batteries. Its electrochemical stability window, thermal stability, and ability to dissolve lithium salts offer a platform for producing safer, non-flammable electrolyte formulations. PMIAc reduces the vapor pressure of the electrolyte system, minimizing risk of leakage or explosion, while sustaining high ion mobility necessary for efficient charge-discharge cycles.

    Industry compliance standards

    • UN Manual of Tests and Criteria, Part III, subsection 38.3 (Lithium battery transport)
    • IEC 62660-2 for lithium-ion battery safety performance
    • RoHS Directive 2011/65/EU for hazardous substances restriction
    • UL 2580 for battery system safety

    Typical usage ratio

    • In battery electrolyte blends: 10%–40% v/v of total electrolyte, depending on compatibility with other solvents and target cell performance.

    Downstream process integration

    • PMIAc is mixed with primary solvents (such as ethylene carbonate) and lithium or sodium salts; formulation filling is performed in dry room conditions prior to cell sealing.

    Final product types

    • Lithium ion pouch and cylindrical cells
    • Sodium ion batteries
    • Rechargeable battery modules for electric vehicles
    • Stationary energy storage batteries

    4. Pretreatment Additive in Biomass-to-Biofuel Conversion

    Advanced biofuel refineries employ PMIAc as a pretreatment solvent for lignocellulosic biomass, facilitating separation of cellulose, hemicellulose, and lignin. The presence of PMIAc disrupts hydrogen bonding in biomass, enhancing enzyme accessibility for subsequent saccharification and fermentation. This approach increases fermentable sugar yields while decreasing reliance on corrosive acids or bases, leading to improved downstream fermentation efficiency and higher overall biofuel yields.

    Industry compliance standards

    • ISCC PLUS for sustainable biomass processing
    • US EPA Renewable Fuel Standard (RFS) pathway compliance
    • EN 15940 for paraffinic diesel fuel quality
    • ISO 22000:2018 Food Safety Management (where cellulosic ethanol is used as a food additive carrier)

    Typical usage ratio

    • Biomass loading: 5%–20% w/w solid in ionic liquid, optimized according to feedstock species and target monosaccharide recovery.

    Downstream process integration

    • PMIAc is blended in the pretreatment reactor with milled biomass; following solubilization, anti-solvent precipitation recovers cellulose for hydrolysis.

    Final product types

    • Cellulosic ethanol biofuel
    • Fermentable sugar syrups
    • Biorefinery intermediates for green chemicals production
    • Lignin-rich residues for energy recovery

    5. Anti-Solvent Precipitation Media in Pharmaceutical API Crystallization

    API manufacturers apply PMIAc in controlled crystallization processes as a green anti-solvent or recrystallization medium, especially for compounds with limited solubility in conventional organic solvents. Its selective solvation properties and minimal vapor pressure facilitate improved crystal purity, particle size control, and reduction in polymorphic variability. This enables more reproducible downstream formulation development and complies with strict pharmaceutical impurity limits.

    Industry compliance standards

    • ICH Q3A/B for impurity limits in APIs
    • US FDA Current Good Manufacturing Practice (cGMP) 21 CFR Parts 210/211
    • European Pharmacopoeia (Ph.Eur.) standards for API crystallization solvents
    • JP Pharmacopoeia general notices for solvent use in active ingredients

    Typical usage ratio

    • Crystallization solvent:API loading of 5:1 to 20:1 (v/w), ratio selected by solubility curves and targeted particle properties.

    Downstream process integration

    • API solution prepared in primary solvent; PMIAc introduced as anti-solvent to induce controlled precipitation, followed by filtration and washing to achieve required purity.

    Final product types

    • Pharmaceutical-grade APIs
    • Specialty drug intermediates
    • Highly pure API crystalline powders
    • Controlled-release formulation intermediates

    6. Cellulose-Based Composite Film Manufacturing for Packaging

    Packaging material converters integrate PMIAc into cellulose solution preparation for the casting and formation of biodegradable composite films. Its ability to fully dissolve cellulose and allow for blending with biopolymers such as chitosan or starch improves film homogeneity and mechanical properties. PMIAc thus supports the industrial-scale shift from petroleum-based to renewable, compostable packaging with controlled permeability and printability characteristics.

    Industry compliance standards

    • EN 13432:2000 for compostable packaging materials
    • FDA 21 CFR 177.1200 for materials contacting food
    • ISO 1872-1:2019 for film physical property characterisation
    • EU Framework Regulation (EC) No 1935/2004 for food contact materials

    Typical usage ratio

    • Solution preparation: 3%–8% w/w total cellulose and polysaccharide blend in PMIAc solvent, adjusted for film thickness and barrier specification.

    Downstream process integration

    • Batch mixing of cellulose with PMIAc at 80–100°C, followed by film extrusion or solvent casting onto carrier rolls; subsequent water or alcohol wash extracts PMIAc for solvent recovery.

    Final product types

    • Biodegradable packaging films
    • Compostable wrapping sheets
    • Edible packaging components
    • Barrier-coated paper substrates
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    Certification & Compliance
    More Introduction

    1-Propyl-3-Methylimidazolium Acetate: A Closer Look from the Manufacturer’s Bench

    What We See in 1-Propyl-3-Methylimidazolium Acetate

    Shaping raw materials into practical solutions is our daily work, so we get a good look at what makes each compound deliver value on a factory floor. With 1-Propyl-3-Methylimidazolium Acetate—often recognized by its chemical shorthand, [Pmim][OAc]—our team points to the way it bridges gaps between classic solvents and modern ionic liquids. This isn’t an abstract promise, but something you can notice during actual handling and application. Our chemists value the ease with which it dissolves cellulose, polysaccharides, and even some metals. Compared to older systems, which either carry unwanted water or risk rapid evaporation, this acetate salt holds its own in processes needing low volatility. Operations remain smoother, waste is easier to contain, and you tend to see better yields overall.

    Specifications in the Real World

    Actual product purity and moisture levels will shift quality from adequate to excellent. Our standard on 1-Propyl-3-Methylimidazolium Acetate pushes for water content beneath 0.2%—experience shows that even small increases in water skew solubility and complicate drying downstream. Color often tells a surprising amount; a faint yellowish tint results from trace impurities, so a consistently pale transparent liquid comes as a point of pride in our process. For industrial routes using sensitive catalysts or where precise conductivity is needed, monitoring chloride content and residual base matters. Having persistent quality controls for residual sodium, potassium, and starting imidazole keeps the finished product closer to the numbers customers mention in their own audit reports.

    How Process Plants Make Use of This Ionic Liquid

    Deciding which solvent or salt to use rarely depends on a single spec—practical compatibility, ease of recovery, and side reaction risks all influence decisions. Our customers in biopolymer and biomass refining chose 1-Propyl-3-Methylimidazolium Acetate for processing otherwise unfriendly biomass such as wood, straw, and chitin. This liquid helps open up tight cellulose structures, so enzymes and other catalysts can actually do their job during conversion to biofuels or biodegradable plastics. The same features that make it work in biomass also help separate out rare earths and transition metals in hydrometallurgical routes. Membrane manufacturers turn to Pmim Acetate for casting films, because they can refresh, recycle, and wash it out without residue or exotic clean-up steps.

    Electrochemical labs and commercial battery lines often contact us about [Pmim][OAc] for use as non-flammable, thermally robust electrolytes. The ionic conductivity outpaces many old organic solvents, while chemical stability gives edge when cell life and recharge cycles need extension. Considering viscosity, it sits in a “just right” range: fluid enough to pour, but not so thin that it risks evaporating or leaking past seals in finished products. This hands-on versatility leads to genuine cost savings, as maintenance spending and product loss drop over repeated cycles.

    How [Pmim][OAc] Compares to Related Ionic Liquids

    Most customers ask where this acetate salt stands in relation to its cousin, 1-Ethyl-3-Methylimidazolium Acetate ([Emim][OAc]). Shorter alkyl chains like “Ethyl” deliver lower viscosity, but sometimes they struggle with bulkier substrates. Lengthening to “Propyl” hits a sweet spot for both solvency and flow—so cellulose, chitosan, and similar chains dissolve faster at workable temperatures. There’s a reason so much peer-reviewed work in polysaccharide science relies on our acetate version; it actually gets samples into solution rather than forming gels or tarry residues.

    In contrast, using chloride or dicyanamide counterparts in imidazolium salts drives up corrosion and narrow the range of compatible equipment. Acetate brings low corrosivity: stainless tanks, glass reactors, and polymer lines all remain workable without heavy coatings or loss of structural life. Anyone who’s tried recycling solvents in a tight budget setting appreciates that acetate-form ionic liquids resist hydrolysis and decomposition better in the presence of ambient moisture, so recovery setups become simpler and cheaper to run.

    Thermal stability consistently attracts safety-conscious buyers. In operations near ambient to 120°C, decomposition stays minimal. Gas and odor emissions fall well below worker exposure limits—we’ve tracked on-site numbers through dozens of process audits and can confirm ease of ventilation and scrubber design. This sets it apart from butyl or longer-chain imidazoliums, which often cross thresholds and require extra handling protocols.

    What Makes Production Challenging—and Rewarding

    Sourcing true starting imidazoles and ensuring smooth alkylation are tougher than comparable commodity solvents. Our synthesis runs take longer and need scrupulous monitoring, since trace side products can poison downstream applications—especially in polymerization or membrane-casting environments. Every new batch brings an opportunity to push for higher yields, cleaner color, and steadier thermal properties.

    Remembering early years on the production line, managing byproduct removal from bulk neutralization steps brought lessons in reducing both loss and downtime. Acid-base balance during acetate exchange affects not only purity but also waste treatment later on. By refining our distillation and filtration, we reduce fouling and keep ionic strength within repeatable limits. Customers notice this stability in small pilot reactors as well as in full-scale drum shipments, so confidence grows batch by batch.

    Delivering 1-Propyl-3-Methylimidazolium Acetate involves more than laboratory tinkering. We see logistical subjects—shipping under mild, non-hazardous codes, storing at room temperature, and setting up containers resistant to leaching. Our solutions on these fronts draw on regular feedback from chemical plant operators, university labs, and large-scale fermenters.

    The Value of Onsite, Closed-Loop Operations

    Using closed circuits with efficient reclamation gives users significant savings. Inside our own manufacturing, we reclaimed solvents and minimized waste—fewer off-gassing incidents and minimal environmental impacts. These practices rolled out to customer sites, who then reported improved compliance and lower incident rates. Handling [Pmim][OAc] alongside other acetates or ionic liquids in the same facility keeps transition times short between different production campaigns. Equipment doesn’t need complete tear-down between runs, so capacity stays higher year-round.

    End-use application diversity keeps our teams on their toes. Some clients focus on extracting plant-based fibers, others modify pharmaceutical intermediates, and a few test its use as a temporary solvent for robotic and 3D-printed scaffolds. Feedback from these groups reinforces our decision to continually test reaction compatibility and to monitor every output for trace contaminants. These details matter—one stray impurity can stop a whole production run or spoil a critical batch.

    Industry Case Studies: Field-Driven Insight

    A team in cellulose film production implemented our 1-Propyl-3-Methylimidazolium Acetate to replace a traditional solvent mix plagued by slow dissolution and high evaporation losses. Actual throughput on their casting line reportedly increased nearly 30%, while overall waste solvent dropped by several tons per month. Maintenance logs tracked lower filter fouling and fewer unscheduled stops. In pharmaceutical synthesis, a contract manufacturer managed to cut out an additional distillation stage when switching to our acetate, freeing up labor while recovering more usable product per drum of ionic liquid consumed.

    Over in the battery cell development sector, our technical staff helped partners swap hazardous carbonates for [Pmim][OAc]. Besides improved safety stats (including a record zero chemical exposure events over four quarters), end-of-life recycling simplified. The acetate’s low vapor pressure meant less off-gassing and fewer emissions, while cell cycling tests showed extended charge retention relative to earlier candidates. These aren’t laboratory demos—real plant records underscore reliability and value, from pilot runs through full-scale commercial lines.

    Meeting Regulatory Scrutiny: Practical Approaches

    Any site handling chemical manufacturing stands under increasing regulatory oversight. Our own plant’s continuous improvement teams keep a close eye on compliance with hazardous substance directives, but the appeal of [Pmim][OAc] comes from its relatively low toxicity and low reactivity. Direct shipment under non-hazardous codes streamlines customs clearance, and in Europe and Asia, permitted process limits read favorably compared to many alternatives.

    Scrupulous records back every drum shipped, down to full batch traceability and impurity certificates by request. Quality management integrates feedback directly from client returned samples and ongoing inspection audits. It isn’t just box-ticking—we find that actively sharing analytical results makes it easier for users to adapt to new or tighter local targets. Those investing in greener or renewable manufacturing appreciate that both feedstock and byproduct streams can often be further refined or safely disposed of using in-plant equipment.

    Practical Application Hurdles and Solutions

    Many first-time users expect ionic liquids to match solvent behavior they are used to. Viscosity and water tolerance need adaptation in process engineering. We advise keeping lines warm if handling in unheated warehouses, since product thickens under 5°C. Our field staff sometimes recommend custom pre-heating hoppers for winter months, which avoid unnecessary blockages and pump failures. Where drying or solvent exchange is part of the program, vacuum stripping helps ensure complete removal of residual water, boosting consistency from batch to batch.

    A challenge with [Pmim][OAc] is its affinity for absorbing moisture from air. Simple precautions, like using sealed transfer equipment and employing real-time Karl Fischer water monitors, wring extra quality from every transfer. In applications like enzyme-catalyzed reactions, real-time in-line monitoring assures customers their results won’t veer off target. Direct experience proves these steps prevent lost time and reduce off-spec output.

    How Our Production Stands Out—Beyond Supply

    Our team traces every kilo of [Pmim][OAc] from incoming raw materials to outbound finished goods. Dedicated finishing units support fast response for custom orders and deliver rapid turnaround when end-use demand spikes. On-the-fly filtration and adaptive dehydration mean urgent orders rarely face delay once processed through QA. We’ve rolled out continuous process improvements driven by operator feedback—these tweaks, sometimes as simple as changing a filter or adjusting reactor agitation, make visible gains in product clarity and batch yield.

    Long-term customers return for both the material itself and the technical backup behind it. Our in-house applications engineers regularly join pre-launch pilot trials to troubleshoot installation and scale-up snags, from filter clogging to foaming during mixing. Over the past decade, improvements made through these partnerships led directly to the series of product innovations available today.

    Environmental and Sustainability Initiatives

    We see pressure growing for renewably sourced materials and responsible byproduct handling. Our work here isn’t theoretical—it cuts costs while shrinking environmental impact. Pmim Acetate production benefits from process streamlining that reduces solvent loss, reuses water internally, and even provides options for recycling spent ionic liquid fractions into fresh batches. These ideas came from tight internal collaboration, but their impact shows up most in lower annual waste disposal bills and positive third-party audit outcomes.

    Interest in circular chemistry means more clients want to know how their spent solvent can be recovered or repurposed. We test each returned container and share feedback on recoverable volume and potential upgrades. Some batches see nearly full material recovery after reconditioning, while others produce side products suitable for secondary uses—such as low-impact cleaning solutions in non-critical tasks. We share data openly, so end-users can match recovery approaches to their local regulations and environmental targets.

    Building for the Future

    Developing cleaner, more consistent ionic liquids like 1-Propyl-3-Methylimidazolium Acetate demands more than attention to theoretical purity. Our workplace culture keeps open lines of communication—from production operators to shipping teams—so practical lessons translate into tweaks that speed production, cut error rates, and build reliability. Direct feedback from research partners and end-user plants anchors our ongoing R&D, centering process improvements around genuine field data rather than generic wishlists.

    Field calls and site visits revealed routinely overlooked wear points in pumps and valves, prompting us to trial and then roll out a new line of compatible gaskets and seals. As new environmental limits and “greener” factory benchmarks come into focus, our engineering group partners closely with clients to cut cross-contamination and manage solvent recovery costs.

    Summary from the Plant Floor

    Years at the chemical plant teach that dependable quality and honest performance make all the difference. For industries navigating the shift from legacy solvents to modern, safer, and more sustainable chemistries, 1-Propyl-3-Methylimidazolium Acetate solves real process problems while offering room for continuous improvement. Every challenge yields a new lesson; every batch milestone earns trust. By staying grounded in facts, supporting each claim with lived practice, and working directly with partners, our team believes this acetate model continues evolving—meeting industry needs head-on, one shipment at a time.