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1-Phenyl-2-Propanol

    • Product Name 1-Phenyl-2-Propanol
    • Alias α-methylbenzyl alcohol
    • Einecs 202-856-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    169629

    Cas Number 533-52-6
    Molecular Formula C9H12O
    Molecular Weight 136.19 g/mol
    Iupac Name 1-Phenylpropan-2-ol
    Appearance Colorless to pale yellow liquid
    Melting Point -30 °C
    Boiling Point 219-221 °C
    Density 1.01 g/cm³ at 20 °C
    Refractive Index 1.517-1.519
    Solubility In Water Moderately soluble
    Flash Point 92 °C
    Smiles CC(CO)C1=CC=CC=C1
    Synonyms alpha-Methylbenzyl alcohol, 2-Phenyl-1-propanol

    As an accredited 1-Phenyl-2-Propanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1-Phenyl-2-Propanol, 100g, supplied in a sealed amber glass bottle with tamper-evident cap and clear hazard labeling.
    Shipping **Shipping Description for 1-Phenyl-2-Propanol:** 1-Phenyl-2-Propanol should be shipped in tightly sealed containers, protected from light and moisture. Store and transport at room temperature in compliance with local regulations. Ensure appropriate labeling and include safety data. Handle with care to prevent leakage or contact, as the compound may cause skin and eye irritation.
    Storage 1-Phenyl-2-Propanol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers. Keep away from direct sunlight and moisture. Store at room temperature and ensure proper labeling to prevent accidental misuse or exposure. Handle with appropriate personal protective equipment (PPE).
    Application of 1-Phenyl-2-Propanol

    Applications of 1-Phenyl-2-Propanol in Industrial Manufacturing

    1-Phenyl-2-Propanol plays a distinct role in various fine chemical and high-value industrial synthesis processes. As a direct manufacturer with dedicated experience in consistent batch production, we supply this raw material to select downstream sectors where its attributes support regulatory compliance, formulation stability, and reproducible process performance. Below is a detailed overview of real-world application scenarios based on industrial practice and customer feedback.

    1. Pharmaceutical Intermediate Synthesis (e.g., for Phenylpropanolamine and Related Compounds)

    Pharmaceutical ingredient manufacturers utilize 1-Phenyl-2-Propanol as a critical building block for synthesizing key intermediates, particularly within the phenylpropanolamine and related amine synthesis routes. The material’s alcohol group and aromatic structure facilitate specific hydrogenation, oxidization, or substitution reactions, essential for multi-step API and excipient formulations, especially under GMP conditions. Its reactivity plays a decisive role in determining yields and controlling by-product formation in cGMP batch reactors.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • USP/NF and EP excipient monographs (where applicable)
    • REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals, EU)
    • 21 CFR Part 211 (US FDA)

    Typical usage ratio

    • 0.8–1.2 molar equivalents relative to target API intermediate, frequently adjusted per route efficiency and batch volume

    Downstream process integration

    • Added at the reductive amination or Grignard reaction step in multi-stage pharmaceutical ingredient syntheses

    Final product types

    • Bulk pharmaceutical intermediates (e.g., phenylpropanolamine, phenylpropanone derivatives)
    • Finished APIs for cold medication and nasal decongestants
    • Fine chemical intermediates used in further modification or coupling

    2. Fragrance and Aroma Compound Manufacturing

    Industrial perfumery and fragrance ingredient manufacturers employ 1-Phenyl-2-Propanol as a direct or modified component in the creation of floral and fresh odor notes. Its stability under reaction and blending conditions allows for controlled integration into complex aroma profiles, either via acetylation or as a primary alcohol base built into higher esters. Aroma compound lines benefit from both its characteristic scent and ability to function as a precursor for further molecular tailoring during synthesis scale-up.

    Industry compliance standards

    • IFRA (International Fragrance Association) Standards
    • EU Regulation (EC) No 1223/2009 (Cosmetic Products Regulation)
    • RIFM (Research Institute for Fragrance Materials) Quality Guidelines
    • ISO 9235:2013 (Aromatic natural raw materials)

    Typical usage ratio

    • 0.5–3.0% by weight in concentrate or compound formulations; exact percentage determined by target olfactory impact and downstream esterification yield

    Downstream process integration

    • Incorporated at the esterification or acetalization phase prior to blending with carrier solvents and fixatives; alternatively, supplied as-is for direct blending in top-note compositions

    Final product types

    • Perfume and Eau de Toilette concentrates
    • Floral and fresh-type aroma molecules
    • Scented consumer goods (air fresheners, scented candles)

    3. Flavor Ingredient Synthesis for Food Additive Producers

    Food-grade manufacturers incorporate 1-Phenyl-2-Propanol, under regulatory allowance, as an intermediate in the synthesis of flavoring substances imparting mild floral and sweet notes for the processed foods sector. Under high-purity control, this material enters select synthetic flavor lines either as a precursor or by conversion to corresponding esters used for baked goods, confectionery, and beverage enhancement. Downstream partners monitor its conversion ratio to comply with stringent food additive legislations across regions.

    Industry compliance standards

    • FCC (Food Chemicals Codex) monograph where applicable
    • 21 CFR 172.515 (US FDA: Synthetic flavoring substances and adjuvants)
    • EU Regulation (EC) No 1334/2008 (EU Flavouring Regulation)
    • ISO 22000:2018 (Food safety management systems)

    Typical usage ratio

    • 0.01–0.1% of total blend mass after conversion to authorized esters or flavor compounds; precise levels dictated by GRAS listings and regional MRLs

    Downstream process integration

    • Processed in esterification vessels for flavor ester production or blended in trace quantities during final liquid compounding

    Final product types

    • Synthetic flavor blends for bakery and candy manufacturers
    • Esters for beverage and dairy flavoring systems
    • Ready-to-use liquid or emulsion flavor additives

    4. Fine Chemical and Specialty Solvent Production

    Chemical synthesis plants utilize 1-Phenyl-2-Propanol within fine chemical production lines, particularly for specialty solvent or intermediate manufacture. The primary alcohol group and phenyl ring provide sites for targeted functionalization, including oxidation to ketones or acylation, enabling supply chains in chromatographic standards and custom synthesis for laboratory analysis reagents. Its consistent physicochemical profile assists downstream operators in maintaining analytical reproducibility and chemical specification controls.

    Industry compliance standards

    • ISO 9001:2015 (Quality management systems)
    • ISO 17034:2016 (General requirements for the competence of reference material producers)
    • Specific downstream customer analytical method protocols (GLP, ISO, ASTM)
    • REACH (chemical safety for Europe)

    Typical usage ratio

    • Varies from 2–25% depending on desired concentration for solvent blend or as limiting reagent for reference standard synthesis; regulated by application-specific purity and assay requirements

    Downstream process integration

    • Charged during batch solvent blending or added to precision-controlled reaction vessels for selective oxidation/acylation

    Final product types

    • Specialty solvents for laboratory and analytical use
    • Reference standards for chromatographic analysis
    • Fine chemical intermediates for custom synthesis labs
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    Certification & Compliance
    More Introduction

    1-Phenyl-2-Propanol: Proven Chemistry, Trusted Manufacturing

    The Role of 1-Phenyl-2-Propanol in Modern Chemical Manufacturing

    At our facility, we have learned that subtle shifts in molecular design often translate to big changes in how a chemical fits into the manufacturing puzzle. 1-Phenyl-2-propanol represents one such case: its clean, secondary alcohol structure with a phenyl group grants it a balance of reactivity and selectivity—qualities that have grown increasingly important across fragrance, pharmaceutical, and specialty intermediate production. Our experience with the compound stretches back over a decade, during which time we refined our processes with close attention to purity, consistency, and safety. As a direct manufacturer, we see every variable that feeds into the final product, from selecting high-quality benzene-derived feedstock, through batch distillation, to tailored purification protocols. These influence everything from reaction yields to downstream handling, and set industrial-grade material apart from bulk, commoditized alternatives.

    Specifications That Make a Difference

    In the market, not every sample of 1-Phenyl-2-propanol conforms to the same standard. The specific demands of aromatic compound synthesis taught us that even trace impurities affect product quality, reactivity, and long-term stability. Over hundreds of production runs, we optimized for typical purity levels of 99% or higher on a GC area percent basis, with water content routinely controlled below 0.2%. Such diligence prevents adverse reactions—especially in pharmaceutical or fragrance settings, where off-odor, color formation, or side reactions can undermine end-product value. Physical characteristics also come into play. 1-Phenyl-2-propanol flows as a colorless to pale yellow liquid at ambient temperature, exhibiting a mild, characteristic odor. Its boiling point sits above 215°C, and it maintains stability for extended periods in inert storage. We learned that moisture control, drum selection, and careful inerting can make the difference between a clean batch and a contaminated outturn. Logistics teams and tank farm operators have come to rely on batch-to-batch consistency, as even slight color changes spark investigation.

    How Our Process Shapes the Outcome

    From upstream selection to final QC, every step shapes the quality of 1-Phenyl-2-propanol. Our technical team continually logs unit conditions, monitors byproduct profiles, and optimizes reactor residence times. Over time, our plant engineers discovered that slight temperature drifts during hydrogenation introduced unwanted byproducts, so we invested in improved process control and in-line monitoring. The result: we regularly supply lots meeting stringent aromatic purity standards, which prove critical to pharmaceutical intermediates where regulatory scrutiny runs high. On the safety front, we adhere to strict closed-system handling, as 1-Phenyl-2-propanol—while not highly toxic—warrants careful management to aid safe downstream use. Every drum leaving our yard comes with a certificate of analysis that reflects our philosophy of full accountability from raw material to finished product.

    Applications We See Most Frequently

    Day-to-day, much of our output feeds into fragrance production, where 1-Phenyl-2-propanol’s clean, floral, and slightly spicy notes help round out high-end blends. Its solubility profile—mixing well with alcohols, esters, and many oils—opens room for creative perfumery and flavor work. Key customers use it as an intermediate for pharmaceuticals that require tight impurity profiles, as secondary alcohols provide the right balance for specific coupling or reduction reactions. Physical purity and sensory neutrality help avoid background flavors and odors, critical for regulatory approval and consumer acceptance. Chemical companies blending intermediates for agrochemical applications value its role in synthesis chains, leveraging its clean breakdown and manageable toxicity. Having supplied a wide range of industries, we have seen that the best results stem from a solid understanding of downstream requirements, and persistent communication between process chemist and supplier.

    What Sets 1-Phenyl-2-Propanol Apart From Related Compounds

    During long discussions at the plant, our chemists explored how 1-Phenyl-2-propanol distinguishes itself compared to primary aromatic alcohols or unsubstituted secondary alcohols. The main difference springs from the positioning of the phenyl group alongside the secondary alcohol functionality. This structure introduces a unique balance: the compound shows greater chemical stability than primary phenylalkanols while retaining enough reactivity for efficient esterification, oxidation, or reduction. In practical terms, this means better control over reaction outcomes, fewer side reactions, and a greater margin for process optimization. By contrast, phenylethanol or benzyl alcohol display higher reactivity to certain oxidants, which sometimes complicates formulation. Compared to other secondary alcohols, our product carries a distinctive aromatic profile, giving it a premium touch in fine fragrance work where both olfactory and performance criteria matter. This is why perfumers continue to request it by name, regardless of competing substitutes.

    The Importance of Product Traceability

    Markets have grown more demanding in recent years. As product safety regulations and customer expectations rise, we see traceability evolving from an afterthought to a purchase requirement. From the moment raw materials arrive at our gates, every lot passes through rigorous internal QC, with batch records that follow the material through blending, purification, packaging, and dispatch. These systems enable quick response to customer queries, as we can identify processing conditions and raw sources in seconds. For 1-Phenyl-2-propanol, this means that pharmaceutical and fragrance manufacturers gain confidence not only in consistency, but in the reliability of the supply chain. In a recent customer audit, robust tracking contributed to contract renewals and supply chain preference. Many buyers care as much about trust and compliance as they do about price or technical specification.

    Quality Risks and the Learning Curve

    Our team has witnessed quality risks that are sometimes overlooked by less-experienced operators. Small shifts in feedstock composition, or use of poorly cleaned equipment, can introduce aldehyde byproducts or traces of other aromatic impurities. We found that extended storage in suboptimal containers causes color changes or the appearance of faint sour notes, a red flag in the fragrance and flavor sectors. Low-quality material can also deliver a weaker fragrance profile or compromised chemical performance. These pitfalls have reinforced our commitment to enclosed transfers, vacuum-sealed drums, and thorough instrument calibration between runs. Even after years in production, our QC team routinely reviews outlier samples to hunt down root causes, not just treat symptoms.

    Supporting Product Development and Process Innovation

    Many customers arrive with specific project needs, from pushing yield boundaries in pharma intermediates to creating a new signature scent. As manufacturers, we maintain an open-door approach to supporting process scale-up, application testing, and exploratory trials. For example, we have supplied kilogram and multi-ton lots for plant trials, adjusting batch sizes or packaging to synchronize with customer line demands. Feedback from development chemists and scale-up engineers directly influences our own process refinement, whether that means tighter control of certain byproducts or investigating catalytic alternatives. A few years ago, a customer flagged that a competing batch exhibited higher volatility and color instability; we invited their technical team to audit our lines, an exercise that led us to introduce upgraded filtration and more frequent tank screening. This iterative approach keeps us at the forefront, delivering more than just a commodity.

    The Value of Close Supplier Collaboration

    Strong supplier partnerships make a difference on technical projects where quality and responsiveness drive the schedule. We have seen firsthand how last-minute adjustments to delivery timing, packaging, or formulation capability can prevent costly downtime or project delays. Customers benefit when both teams combine process data and operational insight to tweak formulation parameters or optimize storage and handling—from drum selection to advice on atmospheric protection. Our approach prioritizes open communication, shared documentation, and site visits when needed. Whether troubleshooting filtration methods, reviewing spec sheets, or fielding a product complaint, our team treats customer concerns as mutual challenges, not externalities. This shared philosophy helps both sides respond faster when regulatory, operational, or commercial stakes run high.

    Regulatory and Environmental Considerations

    With tightening global regulations, sourcing requirements now go far beyond technical data. Sustainability and safe handling play a larger role in purchasing decisions. In our own operations, we have invested in closed-loop waste recovery, emissions minimization, and water use reduction—steps that help us control material cost and support long-term viability. For customers driven by green chemistry mandates, we share detailed lifecycle data and assist with downstream compliance queries, including documentation for reach and other relevant chemical control regimes. Our approach to regulatory change remains practical; each adjustment is analyzed with both safety and downstream compatibility in mind. We see benefits not only in compliance but in supply chain security, as well-managed plants face fewer interruptions from unanticipated regulation.

    Challenges in Consistent Supply and What We’ve Learned

    The last several years taught us that keeping supply running smoothly involves more than optimizing one’s own processes. Raw material volatility, shipping challenges, and variable demand all require rapid, informed adaptation. As manufacturers, we monitor upstream benzene market trends, logistical bottlenecks at ports, and delivery schedules for critical reagents. In response to pandemic disruptions, we expanded local storage, lined up redundant suppliers for key inputs, and cross-trained operations staff. The result was a resilient operation that kept customers supplied even as other vendors struggled. For a specialty product like 1-Phenyl-2-propanol, this kind of planning defines who is reliable in the long run.

    Addressing Common Problems in Customer Applications

    Over years of technical support, we have encountered several recurring customer challenges: unwanted coloration, minor off-odors, drum leakage, or compatibility issues with downstream ingredients. Technical teams often pull us in for root cause evaluations. More than once, we tracked the problem to drum contamination from external sources or interaction with poorly cleaned transfer equipment. Sometimes, reactions deviated because of small but significant differences in batch moisture or trace metal content. To address these concerns, we run extensive stress testing, maintain sample retention for several years, and encourage early technical dialogue. These measures have reduced repeat issues and shortened troubleshooting cycles.

    Perspectives on Industry Trends and Evolving Demands

    Industry demand for 1-Phenyl-2-propanol evolves every year. While traditional sectors such as fragrance and flavor remain steady, we see growth from fine chemicals, advanced pharma intermediates, and specialty polymer modifiers. More complex downstream synthesis routes put new pressure on purity, stability, and regulatory compliance. Emerging customer segments pursue higher sustainability and enhanced safety records. These developments push us to rethink both process and service models: modular batch scaling, enhanced digital tracking, and rapid technical support. We recognize that staying relevant as a manufacturer requires not only better process chemistry but also increased transparency and willingness to adapt.

    Our Ongoing Commitment to Technical Leadership

    Having operated as direct manufacturers for years, our experienced technical team knows that every advancement must start with a deep understanding of both raw chemistry and customer context. We continue to invest in analytical technology and advanced process control, confident that every improvement in reproducibility, impurity tracking, and yield contributes directly to customer success. Regular benchmarking helps us maintain an edge: GC-MS libraries for impurity profiling, stereochemistry monitoring, and rapid micro-sampling shorten problem-solving cycles. Where customer processes demand documentation or specific impurity thresholds, we provide full method transparency and respond quickly to change requests. This level of technical leadership stems from years on the production floor, facing the same mix of batch complexity, tight deadlines, and strict regulatory standards that our customers encounter.

    Final Thoughts: What End-Users Can Expect

    Users of 1-Phenyl-2-propanol see the result of choices made at each step in the supply chain. As chemical manufacturers, we know quality is only as strong as the weakest link—from raw material integrity to technical support. Over time, we have built long-term relationships with both buyers and user engineers, committed to delivering more than just product: clear information, fast response, and peaceful confidence that each batch is supported by genuine experience and a relentless drive to get things right. Any manufacturer can put forth specifications, but only a dedicated team committed to improvement every day can deliver the level of reliability that technical markets demand. Our ongoing investment in process, people, and transparency provides a foundation our customers continue to trust.