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1-Octane Sulfonic Acid

    • Product Name 1-Octane Sulfonic Acid
    • Alias n-Octane-1-sulfonic acid
    • Einecs 230-975-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    365228

    Cas Number 126-68-1
    Molecular Formula C8H18O3S
    Molecular Weight 194.29 g/mol
    Appearance White to off-white solid
    Melting Point 60-64°C
    Solubility In Water Soluble
    Ph Of 1 Percent Solution 1-2
    Odor Slight characteristic odor
    Boiling Point 410°C (decomposes)
    Density 1.04 g/cm³ at 20°C

    As an accredited 1-Octane Sulfonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1-Octane Sulfonic Acid is packaged in a 100g sealed amber glass bottle, labeled with hazard information and product details for laboratory use.
    Shipping **Shipping Description for 1-Octane Sulfonic Acid:** 1-Octane Sulfonic Acid is shipped in tightly sealed containers, protected from moisture and incompatible substances. It is classified as a corrosive chemical and must be labeled accordingly. Transport follows local and international regulations, with proper documentation and hazard identification to ensure safe handling and delivery.
    Storage 1-Octane Sulfonic Acid should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from incompatible substances such as strong bases, oxidizing agents, and moisture. The storage area should be clearly labeled and protected from direct sunlight and heat sources. Always use appropriate chemical safety protocols and personal protective equipment when handling.
    Application of 1-Octane Sulfonic Acid

    Applications of 1-Octane Sulfonic Acid in Industrial Manufacturing

    1-Octane sulfonic acid plays a key role as an anionic surfactant and ion-pairing reagent across several industrial sectors. Our production expertise focuses on material solutions strictly aligned with regulatory standards and complex manufacturing processes. Below, we outline specific application scenarios with details on industry compliance, formulation, integration points, and typical end products.

    1. Pharmaceutical Ion-Pair Chromatography Reagents

    Pharmaceutical laboratories and bulk drug producers use 1-octane sulfonic acid as a critical ion-pairing reagent to improve the retention and separation of basic compounds during reversed-phase high-performance liquid chromatography (RP-HPLC). It optimizes peak sharpness and reproducibility in assay validation and impurity profiling, directly supporting API quality release and regulated batch records. This additive interacts specifically with analytes to enhance selectivity in method development for small molecule APIs, monitoring stability, and process impurities, allowing consistent compliance for regulated launches.

    Industry compliance standards

    • ICH Q2 (R2) Validation Guidelines
    • United States Pharmacopeia (USP) General Chapters <795>, <797>, <621> Chromatography
    • European Pharmacopoeia 2.2.29 (Liquid Chromatography)
    • GMP Annex 11 and OECD GLP Guidelines

    Typical usage ratio

    • 0.5–2.0 mM in aqueous HPLC mobile phase; specific ratios tailored during method optimization based on analyte pKa and ionic strength requirements.

    Downstream process integration

    • Preparation of HPLC mobile phase solutions; dissolved in purified water or buffer before admixture with acetonitrile or methanol, followed by filtration and degassing for QC and batch release analysis.

    Final product types

    • Pharmaceutical-grade APIs (e.g., cardiovascular, CNS, antineoplastic agents)
    • Validated analytical standards
    • Stability-indicating QC kits
    • Batch-process impurity profiling reports

    2. Electroplating Brightener Additive

    In the metal finishing sector, formulators incorporate 1-octane sulfonic acid as a grain-refining and brightening agent in nickel and copper electroplating baths. The sulfonic group structure enhances bath conductivity, stabilizes metal ion distribution, and reduces the formation of rough surfaces. Electroplaters leverage its performance to generate uniform, high-gloss plated coatings on electronic components and decorative metal parts, meeting advanced automotive and electronics quality criteria while minimizing rework and rejects.

    Industry compliance standards

    • ISO 4527:2014 (Electroplated coatings of nickel plus chromium)
    • RoHS Directive 2011/65/EU (restriction of hazardous substances)
    • JIS H 8610: Electroplated coatings
    • Automotive OEM plating specifications (e.g., VW TL 245)

    Typical usage ratio

    • 10–80 mg/L in aqueous electroplating baths; dosage adjusted for current density, temperature, and target coating thickness.

    Downstream process integration

    • Direct addition into the recirculating metal plating bath; monitored and replenished via inline chemical feed systems and periodic bath analysis to maintain bath performance parameters.

    Final product types

    • High-grade plated automotive fasteners
    • Consumer electronics chassis
    • Connectors for telecommunications equipment
    • Chrome-finished household appliances

    3. Ion-Pairing Agent for Peptide Purification

    Specialty peptide manufacturers employ 1-octane sulfonic acid during preparative and process-scale reversed-phase chromatography to maximize separation efficiency for complex peptide mixtures. The reagent facilitates improved interaction between hydrophobic peptide fragments and the stationary phase, enabling precise fractionation of target peptides from process-related impurities or geometric isomers, which is essential for consistent batch purity and regulatory compliance in biopharmaceuticals.

    Industry compliance standards

    • US FDA 21 CFR Part 210/211 (cGMP for finished pharmaceuticals)
    • European Pharmacopoeia 2.2.29 (Liquid Chromatography for peptides)
    • ICH Q7 GMP for APIs
    • ICH Q6B Specifications for Biotechnological Products

    Typical usage ratio

    • 1.0–5.0 mM in aqueous-organic mobile phases; concentration optimized based on peptide hydrophobicity and desired resolution for purification scale.

    Downstream process integration

    • Added to the aqueous phase during process chromatography column packing; critical during purification runs for crude peptide mixtures after synthesis and before lyophilization.

    Final product types

    • Therapeutic peptide APIs (e.g., insulin analogs, GLP-1 agonists)
    • Diagnostic peptide standards
    • Custom peptide libraries
    • Research-grade peptide pools

    4. Surfactant for Formulated Specialty Detergents

    Manufacturers of industrial cleaning agents and surface preparation solutions select 1-octane sulfonic acid for fine-tuning the wetting, emulsification, and interfacial properties of specialty detergent blends. Its molecular structure delivers targeted reduction in surface tension and enhanced penetration on metal, glass, or polymer substrates, significantly boosting cleaning efficiency for sensitive electronic, medical instrumentation, and optical lens washing operations.

    Industry compliance standards

    • REACH Regulation (EC) No. 1907/2006 substance registration
    • OECD Test Guidelines for biodegradable surfactants (301 A-F)
    • ISO 9001:2015 Quality Management for chemical manufacture
    • DIN EN 1276 (quantitative suspension test for the evaluation of bactericidal activity) in formulated detergents

    Typical usage ratio

    • 0.1–1.0% w/w in ready-to-use detergent concentrates; adjusted for soil type, rinsability, and detergent format (liquid, gel, or wipe).

    Downstream process integration

    • Blended during the aqueous phase charging sequence; mixed with nonionic or amphoteric co-surfactants under high-shear agitation, followed by QC analysis for foaming and surface activity.

    Final product types

    • Precision instrument cleaning agents
    • Medical device washer solutions
    • Optical glass and lens cleaners
    • Industrial electronic assembly cleaning fluids

    5. Additive in High-Performance Electrolytes for Electrochemical Sensors

    Producers of electrochemical sensors and biosensor cartridges integrate 1-octane sulfonic acid into electrolyte formulations to stabilize conductivity, minimize electrode polarization, and mitigate background noise during measurement of ionic analytes. This targeted use supports consistent sensor calibration, reliable data acquisition, and compliance with rigorous clinical diagnostics and environmental testing protocols.

    Industry compliance standards

    • ISO 13485:2016 (medical devices quality management)
    • USP <791> Conductivity for pharmaceutical water/electrolytes
    • EN 13612:2002 (Performance evaluation of in vitro diagnostic devices)
    • IEC 61010-2-101 Safety requirements for electrical equipment for measurement

    Typical usage ratio

    • 0.2–1.5 mM in sensor buffer or reference solutions; concentration fine-tuned to the ionic strength and operational voltage window required by the device design.

    Downstream process integration

    • Prepared as a component of the working buffer or reference electrolyte; charged into sensor wells or cartridges during automated dispensing and assembly, verified for conductivity and compatibility with electrode materials.

    Final product types

    • Blood gas sensors (e.g., pH, Na+, K+, Cl– electrodes)
    • Clinical diagnostic biosensor cartridges
    • Environmental water quality sensor probes
    • Portable electrochemical test kits
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    Competitive 1-Octane Sulfonic Acid prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 1-Octane Sulfonic Acid: A Practical Perspective from the Manufacturer

    Built Around Consistency, Reliability, and Proven Chemistry

    As a manufacturer of high-purity sulfonic acids, we have spent years refining the production of 1-Octane Sulfonic Acid to meet the expectations of our clients in real-world applications. Our approach roots itself in the lessons learned on the plant floor, in the feedback from laboratory partners, and from the evolving challenges of regulatory standards. The paths our chemicals travel—from the packed columns of our synthesis units to the controlled cleanroom bottling stations—represent a constant focus on quality and predictable results.

    1-Octane Sulfonic Acid (often identified as 1-OSA in laboratory documentation), with the molecular formula C8H18O3S, occupies a unique position in our product range. Across chromatography, specialty surfactant development, and advanced organic synthesis, it delivers the consistent ionic strength and performance required by process engineers and analysts. We know firsthand—since we control every step from raw feedstock through final packaging—what this molecule means to users whose results depend on the quality of every lot.

    Specifications That Matter Where It Counts

    To talk about 1-Octane Sulfonic Acid as a technical chemical only through numbers, purity ranges, or standard certificates misses the point. Real-world demand is not simply about a batch qualifying with a purity above 99%. It's about reproducibility between lots, it’s the lack of interfering by-products, and it’s about getting the right pH stability in application. Our product, typically provided in its sodium or free acid form, is made with experienced attention to every step that influences what actually ends up in your bottle or drum.

    Others may sell from a spreadsheet, but manufacturers deal with the laboratory shelf-life, the storage response to temperature and humidity, and the legwork it takes to avoid cross-contamination at the molecular scale. This means our 1-Octane Sulfonic Acid is protected from oxidizing agents during synthesis, dried with clean nitrogen streams, and sealed under controlled conditions to avoid absorption of atmospheric moisture. Controlling these details translates directly to longer shelf lives, reliable pH control, and no guesswork for anyone using it in high-stakes ion-pairing or surfactant-sensitive reactions.

    What Sets 1-Octane Sulfonic Acid Apart

    Within the world of sulfonic acids, subtle differences separate one product from another even though the molecules might look similar at first glance. For those mixing and matching homologues of the alkane sulfonic acid family, chain length determines much of their physical properties and the way they interact with organic or aqueous phases. 1-Octane Sulfonic Acid, thanks to its eight-carbon backbone, fits a sweet spot—not as short as hexane derivatives or as cumbersome as those stretching past ten carbons. This carbon count means the compound dissolves easily in both aqueous buffers and select organic solvents without introducing excessive lipophilicity.

    Our production runs emphasize tight control on alkane purity, which translates into chromatographic peaks free of ghosting, tailing, or background interference in HPLC ion-pairing protocols. Technicians routinely comment on the ease of phase equilibration and the lack of foaming or emulsification in their made-up solutions. This difference really matters for those working in pharmaceutical analysis, drinking water systems, and industrial surfactant formulation, where unpredictable interactions can drive costs sky-high and set back milestones.

    Application Insights from the Field

    We see most of our 1-Octane Sulfonic Acid sent to labs preparing mobile phase additives for high performance liquid chromatography (HPLC). Those needing strong, predictable retention of basic compounds in reversed-phase methods count on this reagent. Lab teams rely on it because it delivers the right hydrophobicity to interact with both analyte and stationary phase, allowing for clear separation without introducing new contaminants that disrupt calibration curves or method validation.

    In analytical development, where projects hinge on regulatory-compliant, trace-level detection, there is no room for off-spec surfactants or degraded reagents. Analysts want sharp baselines, low noise, and certainty that every repeat injection behaves the same way. Our clients often share stories of chasing erratic peaks from lesser products, only to solve the problem by switching to a batch made with the oversight of an actual manufacturing QC lab.

    Outside of chromatography, research chemists and process engineers value the controlled acidity and surfactant properties of 1-Octane Sulfonic Acid as a molecular tool for dispersing and solubilizing certain classes of molecules during synthetic scale-up. Years of feedback led us to refine our washing and drying steps to ensure minimal residual organic impurities—key factors when this compound supports reactive conditions or serves as a counterion in complex salt formation.

    Pain Points and How Manufacturing Experience Solves Them

    Unpredictable supply, inconsistent quality, and periodic appearance of unknown by-products are unfortunately all too common in the world of commodity chemicals. Traders typically lack both the oversight and technical context to explain away these issues. As a manufacturer, we see every upstream input and every process variable. If a shipment presents high chloride or trace mineral impurities, our in-process analytics catch it long before packaging. Once the equipment has run hundreds of cycles, our feedback systems have tightened process windows well beyond industry minimums—customers receive batches where differences from lot to lot fall within minimal standard deviation.

    A more subtle—and easily overlooked—issue involves packaging. Alkane sulfonates, and their acid forms, readily pick up water if left in the open or packed in subpar containers. We train our packaging crew to understand why a dented drum or misaligned seal isn’t just a cosmetic oversight, but a direct route for in-migration of atmospheric moisture or airborne particles. These points do not make it to glossy catalogs, yet they play out in the final application with measurable effects on consistency and usability.

    The Advantages of Working Directly with a Manufacturer

    Creating 1-Octane Sulfonic Acid is not a point-and-click process—it draws on decades of continuous improvement, real feedback from scientists, and an investment in both hardware and skilled operators. This means our team speaks from direct knowledge when discussing technical hurdles, regulatory documentation, or optimized delivery. Customers gain peace of mind knowing their questions meet with insight straight from those who design, build, and test the product every day.

    Manufacturers bear the challenge of full transparency—something not all market players can offer. Certificate of Analysis (CoA) data, batch history, and impurity profiles come off our own lines. If a contract demands custom concentration, unique solvents, or stability data for an unusual matrix, we can quickly retool and validate in-house. Our clients often cite this direct dialogue as the difference between wasted cycles troubleshooting and a smooth path to scale-up or final release.

    Environmental Responsibility at the Source

    For years, sustainable chemistry seemed like a nice-to-have rather than an essential requirement. Today, expectations have shifted. Manufacturers occupy a central role in ensuring not just batch purity, but responsible handling of all effluents and by-products. Our site draws on advanced condensation and neutralization units that capture and treat any vapor or liquid waste streams. The process chemists who design our pathways evaluate not just yield, but what leaves the stack and what is sent to recycling, all in the cause of reducing environmental risk and protecting team safety.

    1-Octane Sulfonic Acid presents itself as a moderate ecological risk compared to more reactive acids or multi-step halogenated by-products. Yet, attention to containment and disposal chains can avert problems before they reach regulatory reporting or community scrutiny. We implemented real-time sensors across our transfer points and storage tanks, enabling quick intervention if leaks or temperature excursions occur. These efforts stem from repeatedly seeing how minor oversights cascade into regulatory headaches and unnecessary downtime.

    Innovation Driven by User Feedback

    Over time, the uses for 1-Octane Sulfonic Acid expanded. Some years ago, its main role was within mobile phases for HPLC. Feedback from pharmaceutical labs and environmental test facilities steered us to address even trace-level impurities invisible to most chemical traders. Adding gas chromatography and ion chromatography suitability testing widened our user base. Now, food safety labs, water treatment plants, and even electronics shops use this acid for calibration, cleaning, and controlled ionic modification of their working solutions.

    As new protocols call for sharper separation or interference-free backgrounds, our research team stays in close contact with end-users. We often customize specifications—bead size, solvent fraction, color profile—based solely on what actual users face in operation, not on what looks good in a catalog. This ongoing loop between bench chemists and plant operators drives the reliable output we see in every batch shipped. Because we invest in pilot trials, technical support, and follow-through, researchers seldom find themselves unsupported when trying new methods or transitioning to industrial scale.

    Why Not All Sulfonic Acids are the Same

    Even inside the sulfonic acid family, differences in carbon chain length, molecular configuration, and purity profile matter. The eight-carbon chain in 1-Octane Sulfonic Acid grants a balance between hydrophobic and hydrophilic interaction, making it more versatile than either shorter hydrocarbons or long-chain homologues. A too-short chain disappoints in retention power, while a too-heavy backbone interacts poorly with many analytes. Field chemists regularly call out this sweet spot as a reason for choosing 1-OSA over both C6 and C10 variants—less volatility, easier handling, and plenty of method compatibility.

    Experience teaches that every laboratory or production facility is only as reliable as its inputs. We use rigorous incoming QC for the octane base, subjecting every drum and tote to detailed IR, NMR, and mass spec benchmarks. Only suitable material enters the sulfonation unit. Through routine pilot lots and scale-up validations, we fine-tune the conditions—fluorosulfonic acid ratios, contact times, distillation temperatures—ensuring the final product doesn’t bring along any ghosts from the upstream chemistry.

    Meeting the Demands of Regulation and Documentation

    Chemical manufacturers answer to a different set of requirements than distributors—regulatory files, material traceability, and full process validation. 1-Octane Sulfonic Acid shipments include full documentation not because it's expected, but because it handles recurring audits, ISO evaluations, and the increasing demand for lot-specific history. From REACH to TSCA and local equivalents, our compliance group aligns every chemical run with both product stewardship and downstream use.

    By tracking every operator, timepoint, and process condition, we offer clarity when a user questions an analytical blip or a property shift in solution. This mindset shields both users and our reputation from the risks that shadow less-proven supply chains. Batch registration with regulatory partners, third-party laboratory cross-checks, and frequent process revalidation establish both safety and performance credibility.

    Real-World User Stories and Improvements

    Our work doesn't end at the shipping dock. Several of our biggest partnerships grew out of on-site troubleshooting, resolving issues like background staining in capillary columns or unexplained baseline drift in trace water analysis. One major pharmaceutical site traced a critical calibration error to an off-brand sulfonic acid, only to resolve the problem after switching to verified lots direct from our plant. Practical experience with post-shipment support means we routinely advise on dilution protocols, container compatibility, and stability in user-specific storage conditions.

    Requests for custom packaging or altered concentrations spurred us to invest in more flexible, smaller-batch reactors and cleanroom bottling cells. In large-scale industrial surfactant blending, a consistent stream of high-quality starting material minimized the frequency and scale of end-product failures. Over time, these small and large adjustments lead to higher user satisfaction, lower troubleshooting costs, and less wasted time dealing with variable reagent quality.

    Challenges on the Horizon for 1-Octane Sulfonic Acid

    As market demand rises—particularly in Asia-Pacific and South American growth regions—pressures on feedstock reliability and pricing will only increase. Direct involvement in feedstock sourcing, backed by long-term contracts and quality analytics at the source, forms our main hedge against volatility or sudden gaps in supply. Our engineering teams keep a steady eye on energy utilization, tight yield management, and water reclamation, since costs and sustainability tie together more tightly with each passing year.

    A constant challenge remains in supporting regulatory innovation. As governments ratchet up criteria on trace impurities or sustainable process reporting, only manufacturers with in-house expertise and the ability to tweak at the process level will keep pace. Consulting closely with user groups and investing in analytical instrumentation keeps us ahead. The next wave of chromatography, water treatment chemistry, and even precision cleaning will depend on a supplier’s willingness to invest in validation and field support.

    Looking Ahead: Merging Proven Practice with Future Needs

    Our business stands at the intersection of process chemistry, customer feedback, and shifting global standards. Manufacturing 1-Octane Sulfonic Acid to this level of precision is a continual balance—achieved through a mix of plant experience, responsive support, and strict process monitoring. Partnering directly with users helps us drive innovation from real demand, not theoretical forecasts.

    As environmental, analytical, and pharmaceutical users look for ever-tighter performance, they come to trust suppliers who can deliver not just a molecule, but a complete and reliable service. Our team takes pride in knowing the chemistry, understanding the process, and stepping in with genuine expertise when the unexpected happens. That is what defines the manufacturer’s difference: a product engineered, tested, and delivered for those who rely on it every single day.