Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

1-Methylcyclopropane-1-Carboxylic Acid

    • Product Name 1-Methylcyclopropane-1-Carboxylic Acid
    • Alias 1-Methylcyclopropane-1-carboxylic acid
    • Einecs 628-199-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    920411

    Chemicalname 1-Methylcyclopropane-1-Carboxylic Acid
    Casnumber 10472-24-9
    Molecularformula C5H8O2
    Molecularweight 100.12 g/mol
    Appearance White to off-white solid
    Meltingpoint Approx. 84-86°C
    Solubilityinwater Slightly soluble
    Smiles CC1(CC1)C(=O)O
    Inchi InChI=1S/C5H8O2/c1-5(2-3-5)4(6)7/h2-3H2,1H3,(H,6,7)
    Storageconditions Store in a cool, dry, and well-ventilated place

    As an accredited 1-Methylcyclopropane-1-Carboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Supplied in a 25g amber glass bottle with screw cap, labeled with chemical name, purity, and hazard information for laboratory use.
    Shipping **Shipping Description:** 1-Methylcyclopropane-1-Carboxylic Acid is typically shipped in sealed, airtight containers to prevent contamination and moisture absorption. It should be packaged according to relevant chemical safety standards and labeled accurately. Transportation must comply with local and international regulations for laboratory chemicals, maintaining a cool, dry environment and avoiding incompatible substances.
    Storage **1-Methylcyclopropane-1-carboxylic acid** should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and bases. Protect from direct sunlight, moisture, and sources of ignition. Store at room temperature or as recommended by the manufacturer, adhering to standard laboratory chemical storage protocols.
    Application of 1-Methylcyclopropane-1-Carboxylic Acid

    Applications of 1-Methylcyclopropane-1-Carboxylic Acid in Industrial Manufacturing

    1-Methylcyclopropane-1-Carboxylic Acid (MCPA) plays an important role in multiple value chains across chemical and pharmaceutical industries. As a direct manufacturer, we support global partners in precise formulation, consistent quality, and regulatory compliance by controlling each batch from synthesis to shipment. See key downstream applications below.

    1. Synthesis of Cyclopropane-containing Pharmaceutical Intermediates

    MCPA acts as a strategic building block in the production of cyclopropane-based active pharmaceutical ingredient (API) intermediates. Process chemists implement it in Grignard and reductive amination reactions to build cyclopropyl motifs, which improve metabolic stability in new drug candidates. Our product’s defined purity supports scale-up for regulated markets, with controlled isomer ratios and tight impurity profiles for GMP synthesis.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • USP/NF for intermediates specification alignment
    • 21 CFR Part 211 – cGMP for Finished Pharmaceuticals
    • EU EudraLex Volume 4 GMP guidelines

    Typical usage ratio

    • 0.2–0.95 molar equivalent, based on final API target structure
    • Adjustable for step yield or byproduct control in multi-step synthesis

    Downstream process integration

    • Introduced during early-phase Grignard addition or cyclopropanation
    • Removed or further functionalized in subsequent hydrogenation or chiral resolution steps

    Final product types

    • Intermediates for antiviral APIs
    • Cyclopropyl-substituted CNS drug candidates
    • Proprietary oncology small molecules
    • Generic cyclopropane-based pharmaceuticals

    2. Agricultural Chemicals: Key Intermediate in Synthesis of Crop Protection Agents

    Multiple pesticide and herbicide manufacturers use MCPA-derived cyclopropane motifs to enhance agrochemical persistence and selectivity. Its three-membered ring allows for the introduction of unique molecular configurations during synthesis of phenylcyclopropyl herbicides and synthetic pyrethroids. Controlled reactivity enables scale-up without excessive side reactions.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • REACH Annex IX (EU) for agrichemical intermediates
    • ISO 9001:2015 Quality Management for agrochemical supply
    • U.S. EPA 40 CFR Part 158 – Data requirements for pesticides

    Typical usage ratio

    • 0.3–1.5 molar equivalents per batch, dependent on desired crop protection agent
    • Optimized based on selectivity of final active ingredient synthesis route

    Downstream process integration

    • Reactant in esterification or amide coupling during parent acid functionalization steps
    • Fed into early-stage batch reactors before final chlorination or sulfonation

    Final product types

    • Pyridine-containing herbicides with cyclopropyl modifications
    • Synthetic pyrethroid insecticides
    • Specialty fungicides containing cyclopropane substructures

    3. Fine Chemical Synthesis: Custom Cyclopropane Intermediates for Flavors and Fragrances

    Flavor and fragrance compound manufacturers incorporate MCPA for the unique ring strain of cyclopropanes, affecting olfactory characteristics. Key steps include direct carboxylation or esterification, leading to structurally complex cyclical molecules that form the basis of synthetic aroma chemicals. Strict byproduct monitoring ensures absence of off-flavors in downstream applications.

    Industry compliance standards

    • IFRA Code of Practice for fragrance ingredients
    • FEMA GRAS status for suitable derivatives
    • ISO 9001:2015 for fine chemical manufacturing
    • EU Regulation (EC) No 1334/2008 – flavoring substances

    Typical usage ratio

    • 0.05–0.3% by mass of starting blend, depending on required cyclopropane note
    • Adjusted per batch for target aroma profile and stability

    Downstream process integration

    • Carboxylic acid input for batch esterification under controlled temperature
    • Intermediate in Diels-Alder reactions for cyclic fragrance synthesis

    Final product types

    • Cyclopropyl-based fragrance compounds
    • Artificial fruit flavor derivatives
    • Specialty aroma enhancers for beverages or confectionery

    4. Polymer Modification and Performance Monomers

    MCPA can serve as a specialty monomer precursor for cyclopropane-functionalized polymers and copolymers, especially in advanced materials demanding high strain energy or unique solubility characteristics. Downstream R&D groups incorporate it by initiating ring-opening polymerizations, yielding polymers with improved thermal properties or enhanced resistance profiles. Purity specs and controlled moisture limit side reactions when scaling from pilot to commercial runs.

    Industry compliance standards

    • ISO 9001:2015 for downstream specialty polymer manufacturing
    • ASTM D256, D638 for mechanical testing of final plastic properties
    • RoHS 2011/65/EU for electrical insulation use
    • FDA 21 CFR 177.2600 for elastomeric materials in food contact (when applicable)

    Typical usage ratio

    • 0.5–5 mol% in copolymerization, varied to achieve desired crosslink density
    • Adjusted for targeted mechanical or dielectric property setpoints

    Downstream process integration

    • Fed to reactor at early polymerization stage as comonomer
    • Derivatized prior to ring opening, followed by co-oligomerization

    Final product types

    • Cyclopropane-modified engineering plastics
    • Crosslinked rubber sealing materials
    • Specialty high-dielectric thermosets
    • Custom copolymers for electronics encapsulation
    Free Quote

    Competitive 1-Methylcyclopropane-1-Carboxylic Acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing 1-Methylcyclopropane-1-Carboxylic Acid: Reliability from Direct Manufacturing

    Our Long-Term Expertise with 1-Methylcyclopropane-1-Carboxylic Acid

    For years now, our team has been developing and refining the production of 1-Methylcyclopropane-1-Carboxylic Acid. This experience has taught us how each lot’s purity, stability, and form can influence results throughout the chain from lab bench to plant floor. Unlike resellers who only pass along what’s already in a barrel, we control our synthesis from raw stock through to final packaging, with all the adjustments that process knowledge brings.

    We produce this compound using cyclopropanation methods that maintain batch consistency and meet the clarity researchers expect. Every technical and research team that comes to us tends to ask about reproducibility. In-house production, not simple repacking, lets us stand behind our answers and support specific customizations that match our partners’ needs.

    Physical Profile and Key Specifications

    The pure form of 1-Methylcyclopropane-1-Carboxylic Acid appears as a white to off-white solid. Our experience shows most laboratories demand at least 98% purity to avoid side reaction concerns in plant hormone research, chemical syntheses, or reference testing. Moisture content and melting point must stay inside tight limits. We never treat those as checkboxes—every specification figures into the reliability of customer results, so every batch runs through full analysis: NMR, HPLC, solid-state checks, and certified reference comparisons.

    Some end-users request higher-purity or special lots for highly sensitive work. Since we handle the whole process ourselves, we tune synthesis and purification approaches to achieve finer purity fractions or reduced solvent residues as needed.

    Role and Application Scope

    Most scientists and technical staff we work with source 1-Methylcyclopropane-1-Carboxylic Acid for use in plant physiology research, not for mass agricultural deployment. The focus often lands on pathways involving ethylene biosynthesis, since this compound acts as a precursor or inhibitor in certain systems. Our close involvement with industry and academic partners shows that careful control over contaminants is vital when mapping hormone interactions—trace impurities in the acid can send data off course.

    Beyond research, chemical synthesis groups sometimes use this product as an intermediate or starting compound. We’ve seen creative functionalization projects that benefit from the ring structure’s efficiency in downstream steps, whether scaling up for development or fine-tuning small molecule libraries for drug discovery.

    Our team gets regular questions about the practicality of using this compound versus closely related acids or cyclopropane derivatives. The ring strain and precise substitution pattern on the methylcyclopropane core give it unique reactivity, helping produce results difficult to replicate with linear or branched analogs.

    What Sets Our Product Apart from Similar Cyclopropane Carboxylic Acids

    Production expertise plays a massive role in the outcome of downstream projects. Compared with cyclopropanecarboxylic acid or methylated variants lacking the correct ring position, 1-Methylcyclopropane-1-Carboxylic Acid introduces a three-membered core that brings both higher reactivity and more pronounced effects in biological contexts. The additional methyl group alters sterics, helping model delicate molecular recognition events.

    Over time, we’ve run head-to-head analyses comparing material we produce alongside commercially available cyclopropane acids from bulk suppliers and international exporters. Market products often fall short in batch traceability and documentation, especially for academic or pharmaceutical-grade use. We document the full synthetic route and lot history because we understand the cost of uncertainty.

    Another key difference in our offering comes from post-synthesis handling. Exposure to air can degrade, and inappropriate packaging allows residual solvents or degradation products to creep in. Our in-house packing minimizes transits and exposure. Each shipment comes with chromatograms and spectra, not just a generic certificate most traders supply.

    Why Tight Quality Standards Matter in Science and Industry

    Research teams working on ethylene biosynthesis often fail to find reproducible results across suppliers. We’ve traced these troubles to poorly defined or stale product stocks. Our synthesis batch records tie each step to the resulting fingerprint, keeping cross-study comparisons meaningful. It’s not about over-promising absolute absence of contamination—real results come from controlling and acknowledging the physical and chemical realities of the process.

    Industrial customers scaling up syntheses appreciate direct access to the manufacturer. Instead of relying on what’s left in a third-party warehouse, they communicate with the chemists who actually run the process. This lets them anticipate deviations, request insight for troubleshooting, and order technical splits or test samples with clear origin.

    Our team has sat across the table from process engineers frustrated with off-spec raw materials preventing pilot runs. We provide batch-level guarantees and technical support from synthesis through to post-delivery analyses, so downtime never becomes a guessing game. Knowing your supplier understands the underlying chemistry makes a difference to plant operations, not only paperwork.

    Usage Contexts: From Bench to Pilot Plant

    Academic groups rely on 1-Methylcyclopropane-1-Carboxylic Acid to probe subtle aspects of ethylene signal transduction or fruit ripening models. The margins between effect and no effect can ride on trace-level consistency. Graduate students and postdocs tell us uniformity between orders shapes both the timeline and publication track of their work.

    In small molecule synthesis, innovation on strained ring systems sometimes calls for cyclopropane derivatives like ours. Production teams exploring unique pharmaceutical scaffolds meet practical bottlenecks sourcing stable, contaminant-free acids. We work with them to resolve supply cadence and customize specifications for the subtleties of their next patent or process milestone.

    Quality control teams in both applied biology and chemical synthesis confirm that documented batch lots and technical data shorten analysis workflows. Instead of retesting, they rely on standards that match their internal benchmarks. We often provide retained samples for third-party crosschecks and long-term studies. Open records have helped settle disputes in multi-institution collaborations, something less possible with no-nonsense traders lacking true origin control.

    Supporting Sustainable and Responsible Practice

    Proper chemical stewardship draws on material traceability, minimal environmental impact, and effective resource use. Our process integrates waste management at each step. Cyclopropanation and carboxylation routes produce unique byproducts, but years of process optimization cut solvent usage, enhance recycling, and reduce the environmental load compared with older industry models.

    By producing locally, we lower transport risks and support end-users aiming for regional supply continuity in the face of shipping delays or geopolitical uncertainty. Frequent feedback from domestic and international partners leads us to design improvement in packaging, minimize breakage, and provide proactive handling information—a necessary contrast to the anonymous approach of bulk chemical distributors.

    We see more regulatory interest every year in transparent material origins and chain-of-custody documentation. By keeping everything in-house, we stay on top of audit requirements and streamline compliance responses for our customers. Laboratories and production lines can demonstrate chain clarity in ever-stricter environments, which is growing in importance for grant funding and regulatory filings worldwide.

    Distinct Advantages Over Bulk-Source Products

    Cyclopropane-1-carboxylic acid analogs from bulk sources sometimes showcase yellowing, clumping, or erratic melting points, symptoms of aging or off-spec handling. Our approach to product handling keeps stock viable and quickly traceable to production records. Genuine transparency about how long material has sat post-synthesis improves repeat order reliability and long-term project support.

    Bulk suppliers and intermediaries focus on lowest price, losing sight of the needs that drive research and process innovation. Quality oversight slips, documentation fails to keep pace, and technical support evaporates once the sale is done. Our chemists and QC staff stand ready to answer detailed questions and troubleshoot not just “on paper” but through practical modifications, granting tangible benefit to teams working against deadline and budget.

    Academics and industry partners who switched from generic sources to direct-from-manufacturer material see improvements in synthesis yields, reproducibility of data, and clarity in reporting their research protocols. These results stem from more than purity alone—homogeneous production methods, timely shipment, and responsive support create a foundation for breakthrough results.

    Solutions to Common Procurement and Application Challenges

    A major pain point in chemical research involves orphaned or out-of-spec stocks due to delayed distribution, poorly sealed containers, or insufficient data tracing back to the source. By running direct manufacturer-to-lab supply, we offer consistent availability and reduce the risk of unexpected formulation changes or transit spoilage.

    Another recurring challenge is the ability to adapt production scale up or down without price spikes or delays. We have established flexibility within our own synthesis suites, with modular reactors and technically skilled staff, so we can scale output according to real demand. This stabilizes costs and delivery schedules, helping both large industrial projects and specialized research programs keep moving forward.

    Procurement teams demand documentation for compliance audits, sustainability evaluations, and grant-funded research. We provide detailed batch records, NMR and HPLC data, and process summaries. End recipients have the depth they need for project reporting and don’t have to chase paperwork through opaque supplier networks.

    Customer support matters when technical questions arise mid-project. Direct access to our synthetic team shortens downtime—no need to work through layers of intermediaries who lack technical understanding. We have a practice of returning phone and email queries with specificity, not generic answers, often talking directly with bench chemists or researchers when nuanced troubleshooting is needed.

    Looking Forward: Supporting Innovation With Our Chemistry

    Years of feedback from plant science groups and synthetic chemists shows that better supply means more robust science and faster innovation. Rather than targeting only the highest-volume buyers, we take requests and work with budgets across the spectrum, supporting everything from student research projects to pilot production launches. Input from our clients pushes us to modify our process for even tighter batch reproducibility, clearer documentation, and more environmentally responsible production.

    We view our partnership with end users not as abstract, short-term transactions but as an ongoing effort to empower worthwhile projects. Each new piece of feedback gives us an angle from which to fine-tune both chemistry and logistics. If a limited run detects a subtle impurity, we communicate that upward through production and document the fix, holding ourselves to the same standards our customers expect for their own data and products.

    Conclusion: Manufacturing Support Drives Scientific Success

    Working directly with scientists, process engineers, and procurement professionals shapes the way we produce and deliver 1-Methylcyclopropane-1-Carboxylic Acid. We never treat our material as just another commodity. Our approach draws from years of technical expertise and direct communication, not marketing lingo or empty claims. From synthesis through delivery, we focus on pairing exact technical requirements with accountability, product traceability, and honest customer support.

    The differences between our product and those available from generic suppliers or resellers come down to dedicated process oversight, full documentation, and a genuine responsibility to those using this compound to push new knowledge forward. Whether you need custom specifications, batch documentation, or simply want more clarity about the chemistry behind your supply, our team stands ready to help.