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HS Code |
777987 |
| Product Name | 1-Methoxycarbonylamino-7-Naphthol |
| Molecular Formula | C12H11NO4 |
| Molecular Weight | 233.22 g/mol |
| Cas Number | 13114-94-0 |
| Appearance | Off-white to light brown solid |
| Melting Point | 206-210°C |
| Solubility | Slightly soluble in water, soluble in organic solvents like ethanol and DMSO |
| Synonyms | 1-[(Methoxycarbonyl)amino]-7-hydroxynaphthalene |
| Smiles | COC(=O)Nc1cccc2cc(O)ccc12 |
| Inchi | InChI=1S/C12H11NO3/c1-16-12(15)13-11-6-5-8-3-2-4-9(14)7-10(8)11/h2-7,14H,1H3,(H,13,15) |
| Purity | Typically >98% |
| Storage | Store in a cool, dry place, protected from light |
As an accredited 1-Methoxycarbonylamino-7-Naphthol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 50g package features a sealed amber glass bottle, labeled with product name, hazard symbols, lot number, and storage instructions. |
| Shipping | 1-Methoxycarbonylamino-7-Naphthol is shipped in tightly sealed containers, protected from moisture, light, and extreme temperatures. It is labeled according to chemical safety regulations. Standard shipping involves ground or air transport with documentation outlining hazard and handling instructions. Personal protective equipment (PPE) is recommended during handling and receipt. |
| Storage | **Storage Description (60 words):** Store 1-Methoxycarbonylamino-7-Naphthol in a tightly sealed container in a cool, dry, well-ventilated area, away from direct sunlight and incompatible substances such as strong acids and oxidizers. Avoid moisture and excessive heat. Label the container clearly. Ensure appropriate personal protective equipment (PPE) is available when handling. Follow all relevant chemical safety guidelines and local regulations for storage and handling. |
Applications of 1-Methoxycarbonylamino-7-Naphthol in Industrial Manufacturing1-Methoxycarbonylamino-7-Naphthol acts as a critical intermediate in advanced chemical synthesis, especially in high-value sectors that demand precise molecular modification. As an original manufacturer, we support industrial partners in regulated sectors where reproducibility, batch traceability, and compliance documentation are essential. The following sections outline key, real-world downstream applications and technical considerations. 1. High-Performance Organic Pigments for Plastics CompoundingSpecialty pigment manufacturers employ 1-Methoxycarbonylamino-7-Naphthol as a coupling component for synthesizing naphthol-based azo pigments, such as Pigment Red 170. The compound participates directly in the azo coupling phase, where its high purity ensures consistent color tone and lightfastness. Its carbamoyl functionality aids in forming stable crystalline structures, vital for demanding thermoplastic masterbatch production. Maintaining strict input quality allows converters to meet both food-contact and automotive interior material standards. Industry compliance standards
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2. Active Pharmaceutical Ingredient (API) Intermediate SynthesisPharmaceutical process chemists utilize 1-Methoxycarbonylamino-7-Naphthol as a controlled intermediate in the pathway toward several kinase inhibitor APIs and anti-inflammatory drugs. Its specific aromatic substitution pattern allows selective functionalization, critical during regulated multi-step batch syntheses. Manufacturers perform close analytical monitoring (HPLC, MS) to ensure absence of genotoxic impurities and batch-to-batch reproducibility. Industry compliance standards
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3. Specialty Dye Synthesis for Polyester Fiber ColoringTextile dye manufacturers apply 1-Methoxycarbonylamino-7-Naphthol in the diazo coupling stage to formulate high-strength disperse dyes for polyester fiber. Its controlled reactivity delivers shade reproducibility and migration resistance required for mass dyeing in continuous operations. Our material supports high-purity input streams, which minimizes risk of off-shades and meets OEKO-TEX certification needs. Industry compliance standards
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4. Analytical Reagents for Chromatographic AssaysProducers of analytical-grade reagents incorporate 1-Methoxycarbonylamino-7-Naphthol into reagent kits for quantitative analysis of amines, phenols, and other aromatic compounds via HPLC or UV-Vis spectrophotometry. High lot consistency and documented impurity profiles support reliable calibration standards for certified reference material suppliers. Laboratories demand strict heavy metal and solvent residue controls, achieved through redundant purification protocols. Industry compliance standards
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Over the years, chemists and process engineers have faced their share of challenges handling both the specialty dye and pharmaceutical intermediate markets. From our perspective as the chemical manufacturer, delivering consistent batches of 1-Methoxycarbonylamino-7-Naphthol isn’t just about meeting numbers. It’s a story of raw material management, plant safety, and a daily attention to detail that ensures downstream users—dye formulators, pharmaceutical process chemists, or R&D teams—receive what they actually set out to use, not just what’s promised on a data sheet.
Out in the production halls, this compound—known to us as Model 1MCA-7N—originates from carefully controlled reactions. The naphthol backbone brings strong chromophore properties, supporting deep coloration and reliable performance in applications where color consistency can’t slip. That same backbone reserves value in pharmaceutical synthesis. Most buyers come to us either looking to make specialty colorants or planning to build more advanced structures starting from this unit. Our batches, characterized by a high level of purity and minimal trace contaminant profile, have made their way into both established product lines and experimental pilot projects around the world.
Chemicians know subtle molecular tweaks can push properties into entirely new territory. With 1-Methoxycarbonylamino-7-Naphthol, the positioning of the methoxycarbonylamino group at the one-position allows for superior solubility in polar organic solvents, something that people don’t always realize until they’ve struggled with tougher derivatives or related naphthol compounds lacking the same substituent orientation. Our process stabilizes this group, so the end user experiences reliable dissolution times and avoids batch-to-batch surprises—no clumping, no protracted agitation needed.
Customers working further down the synthesis line comment on how fewer byproducts show up during subsequent steps. That’s because our synthetic route aims to separate the desired product as cleanly as possible, limiting chlorinated or sulfonated impurities which can otherwise build up through the supply chain and create headaches during quality checks. We don’t just rely on automated HPLC reports—in our plant the lab and production teams cross-check every output by both instrumental and hands-on colorimetric controls. This tradition stems from years of side-by-side problem solving, seasoned with the type of skepticism only learned by seeing how small impurities can snowball into large-scale failures in downstream applications.
Beyond synthetic advantages, this compound features thermal stability that broadens its usability. Some clients working in pigment dispersion, for example, request extended heating profiles. Our product withstands moderate thermal cycling, retaining its functional group integrity, which is not always the case for structurally similar naphthol derivatives. There, melting points dip unpredictably and degradation can sneak in. It’s not just a point of pride for our lab—it’s a demand born of sorting out past supply issues for clients who can’t afford unstable intermediates.
From a plant operator’s perspective, 1-Methoxycarbonylamino-7-Naphthol strikes a balance between ease of manufacture and end-use flexibility. Throughout years spent refining the process window for scale-up, the shift from kilogram runs to tonnage orders didn’t require total overhauls—just practical tweaks and a firm grip on raw material supply chains. We source our starting materials on a fixed contract basis, insulating customers from seasonal swings and unplanned logistics headaches. If a market crunch hits, we’ve already buffered key inventories to ensure we keep commitments. Every run receives its own certified quality batch record, filed and double-checked long before anyone packs it for shipping. This kind of track-and-trace control lets technical managers from dye plants, drug makers, or academics see exactly where each drum originates, and trust that any question or problem will get a rapid and honest answer, straight from the source.
Our operators grew with the compound—from stainless reactors set up in the early two-thousands to the new containment bays following stricter safety standards. We maintain a risk management approach that weighs not just chemical hazards, but process bottlenecks, waste load, and operator comfort. Over time, feedstock purification, improved temperature controls, and in-line pH stabilization cut error rates to a minimum. Our process achieves impurity thresholds that let downstream handlers skip unnecessary washings and reconstitution steps, so productivity jumps up and waste drops off. These changes didn’t land overnight—they took rounds of trial, rejected lots, and a stubborn team that refused to accept mediocrity.
For teams handling this molecule in dyes and pigments, coloring power and consistency rank above almost anything else. Mix variability triggers costly downtime in blending, so a standardized parameter set—hue, solubility, melt point, and bulk flow—means the production line can actually run as scheduled. A few years back, a textile house asked about color fastness in one of their signature lines. We fine-tuned crystallization rates and drying protocols to cut out dust and oversized particles—no off-shade spots, no caking in their feeders. Several thousand meters of fabric later, they sent a message back: “You saved our season.” Simple feedback, but one that validated years of incremental progress.
Pharmaceutical customers land on this product route out of a search for stability and predictable reactivity. Trials on parallel intermediates often show variable yields or tough clean-up. Clean structure and a tight impurity window keep their columns unblocked, reduce stress in late-stage purification, and clear a smoother regulatory audit. If a particular route needs a shift—a solvent swap, a different base, or thermal hold—we bring that challenge back in-house for direct lab trials. Our technical support isn’t just a phone line, it’s the same team that ran the last batch, willing to try real-world adjustments based on actual order feedback, not just textbook recipes.
We’ve also learned through feedback how certain filter aids, tank materials, or drying protocols influence final product consistency. Engineers at several large clients report less downtime from filter blinding or crusted out valves after switching to our product—subtle details that only matter on a busy industrial floor. Because we use a stringent internal standard for free acid content and water balance, containers maintain pourability even after longer-term storage. Operators running multi-shift cycles appreciate the reduction in product losses and easier tank cleaning. These improvements feed back into the cycle, where our next batch is just a little better than the last.
A common question we get concerns the difference between 1-Methoxycarbonylamino-7-Naphthol and standard 7-naphthol or related dye intermediates. From our vantage, structural features drive those operational differences you see batch to batch on the plant floor. The methoxycarbonylamino side chain introduces compatibility with more aggressive process schemes—acidic or basic—without causing decomposition or color shift. In contrast, dyes and APIs made from unsubstituted naphthols or simpler aminonaphthols often run into unexpected reactivity, whether that means sidechain breakage or background discoloration.
In direct application, 1-Methoxycarbonylamino-7-Naphthol brings more robust UV stability and smoother incorporation into complex pigment structures. Color batch developers using less specialized naphthols end up wrestling with filter losses, uneven dispersion, and repeated rework. Our users see time savings from a shorter blending window and less patchwork corrective dosing. These gains show up in lower per-batch cost and more reliable technical output. Pharmaceutical users, on the other hand, reference the way this compound’s distribution of electron density facilitates downstream functionalization—meaning transformations happen cleaner and with fewer unwanted side products than with more basic naphthol scaffolds.
It would be easy to point to catalog numbers and spec sheets, but it’s hands-on technical exchanges that tell the real story. More than once, a client’s team has come with a failed synthesis—impurities, side reactions, unpredictable solubility. Our R&D bench duplicated the problem and showed how 1-Methoxycarbonylamino-7-Naphthol performed differently. Adjustments in their reactor protocol, based on our profile, led to successful upscaling. That sort of practical, plant-floor chemistry is what separates a chemical partner from a mere supplier.
As the environmental impact of chemical operations gains attention, manufacturers like us bear a growing responsibility to push for safer, less impactful processes. Our development history with 1-Methoxycarbonylamino-7-Naphthol reflects this push. Recycling of process waters, solvent recovery, and careful capture of volatile organics form the spine of our current procedure. Several process improvements—inline solvent swaps, heat exchange recovery, multi-pass crystallization—support both sustainability and batch control. Waste byproduct streams get evaluated yearly to ensure nothing falls out of standards, and we keep a direct line of communication open between the lab and local regulators.
A practical example arose last year during a review of auxiliary solvents. We phased out certain halogenated options in favor of greener alternatives, reducing both operator exposure and environmental release. Despite the higher up-front expenses, the return comes in fewer compliance hurdles and a safer plant floor. Our customers appreciated the lower trace residues—resulting compounds passed stricter clean-label specifications on their first try. We also chart the use and recycling of every drum, using digital batch records to close the loop on resource use. That’s not just a marketing point, it’s a lived reality for the teams that rely on steady, headache-free supply without hidden environmental costs.
Browsing chemical websites or speaking with trading companies, people often meet the same scripted claims. For us, years of manufacturing 1-Methoxycarbonylamino-7-Naphthol have reinforced the sense that reliability is measured in finished goods, not just slogans. We carry technical memories from every tough order: the time we solved a sticky filtration issue, handled an impurity spike before shipment, or advised a new user on optimizing their charge order for best yield.
As practitioners in this space, we meet every new batch with as much focus as the last. Technical teams visit our plant floor regularly, seeing first-hand how raw inputs become refined cargo. They watch us tweak cooling profiles, monitor drying rates, and manually inspect final crystals under real-world lighting—because true quality comes from lived expertise, not just laboratory values.
We’re proud not just to make a product that checks boxes, but one built up layer by layer through the shared knowledge of a staff dedicated to better chemistry. If project needs shift—volume bumps up, specs get tighter, or a new regulatory reality sets in—we bring data and direct experience to the conversation. No shell games, no deferred answers, just clear, evidence-based commitments grounded in years of molecular problem-solving.
Clients trust our word because they know it’s backed by technical work done right at the source. That means fewer headaches for their teams, more predictable projects, and a partnership that grows batch after batch. In a world filled with shifting claims, that’s a difference you can measure—and one we’ll continue to deliver with every drum of 1-Methoxycarbonylamino-7-Naphthol that leaves our gates.