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1-Dimethylamino-2-Methylpentan-3-One

    • Product Name 1-Dimethylamino-2-Methylpentan-3-One
    • Alias Methylone
    • Einecs 621-040-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    163830

    Iupac Name 1-(Dimethylamino)-2-methylpentan-3-one
    Molecular Formula C8H17NO
    Molecular Weight 143.23 g/mol
    Cas Number 10417-94-4
    Appearance Colorless to pale yellow liquid
    Boiling Point 188-190 °C
    Density 0.85 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 74 °C
    Melting Point -22 °C
    Refractive Index 1.423
    Purity Typically >98%
    Storage Temperature Store at 2–8 °C
    Smiles CC(C)C(=O)CCN(C)C
    Inchi InChI=1S/C8H17NO/c1-7(2)8(10)5-6-9(3)4/h7H,5-6H2,1-4H3

    As an accredited 1-Dimethylamino-2-Methylpentan-3-One factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed HDPE bottle containing 100 grams of 1-Dimethylamino-2-Methylpentan-3-One; labeled with hazard information and chemical details.
    Shipping 1-Dimethylamino-2-Methylpentan-3-One is shipped in tightly sealed, HDPE containers compliant with chemical safety regulations. It is transported as a non-hazardous industrial chemical, protected from moisture, heat, and direct sunlight. All packaging is clearly labeled with product identification and appropriate handling instructions, ensuring safe transit and regulatory compliance.
    Storage **Storage of 1-Dimethylamino-2-Methylpentan-3-One:** Store in a tightly closed, clearly labeled container in a cool, dry, well-ventilated area, away from heat, open flames, and incompatible substances such as strong oxidizers or acids. Protect from moisture and direct sunlight. Use proper chemical storage cabinets if possible. Ensure access is restricted to trained personnel and that appropriate spill containment is available nearby.
    Application of 1-Dimethylamino-2-Methylpentan-3-One

    Applications of 1-Dimethylamino-2-Methylpentan-3-One in Industrial Manufacturing

    As a direct manufacturer of 1-Dimethylamino-2-Methylpentan-3-One, we deliver this specialty intermediate to specialty chemical, pharmaceutical, and agrochemical producers worldwide. Below, we outline the major true-to-market application scenarios where this compound is incorporated, addressing industry compliance, formulation usage, integration in customer processing, and the types of finished goods produced downstream.

    1. Pharmaceutical API Intermediate Synthesis

    Leading pharmaceutical manufacturers incorporate our compound primarily as an advanced synthetic intermediate in the multi-step preparation of CNS-active small molecule drug APIs. This compound participates as a selective building block in the preparation of β-dimethylamino ketone moieties, which contribute to target activity or pharmacokinetic optimization. Users carefully control addition to comply with regulated impurity profiles and intermediate validation protocols. Batch-recorded, GMP-aligned charging procedures and reaction monitoring ensure a reproducible transformation into the desired API, supporting patent-bound synthesis routes adopted by API plants under regulatory scrutiny.

    Industry compliance standards

    • EU EMA Guideline on Specifications: Test Procedures and Acceptance Criteria for New Drug Substances and Products
    • United States Pharmacopoeia (USP) for individual API monographs
    • ICH Q7 (Good Manufacturing Practice for Active Pharmaceutical Ingredients)
    • Chinese Pharmacopoeia for approved therapeutic categories

    Typical usage ratio

    • Applied as an intermediate, batch-controlled at 0.8–1.2 equivalents relative to core starting structure in the key formation step; actual ratio decided by patented synthetic pathway and API impurity limit validation

    Downstream process integration

    • Introduced during intermediate coupling, typically after in situ activation of the primary amine or carbonyl groups, followed by work-up and purification according to validated process flow diagrams

    Final product types

    • CNS stimulant APIs
    • Nootropic drug preparations
    • Chemically modified prescription pharmaceuticals for central nervous system indications

    2. Agrochemical Active Compound Synthesis

    Agrochemical producers rely on 1-Dimethylamino-2-Methylpentan-3-One for synthesizing targeted amide herbicide actives and intermediates in pesticide R&D. The compound’s β-ketoamine functionality directly integrates into the backbone of selective herbicidal molecules. Stringent compliance with agricultural chemical safety and impurity guidelines dictates controlled addition, while pilot and large-scale syntheses require confirmatory residue analysis. These standards help support global registration of crop protection agents and reduce batch-to-batch variability in active ingredient content.

    Industry compliance standards

    • FAO/WHO Specification for Pesticide Intermediates
    • REACH (EC 1907/2006) for chemical safety registration in the EU
    • ISO 9001:2015 for quality management in crop chemical production
    • US EPA Pesticide Registration Guidelines (40 CFR Part 158)

    Typical usage ratio

    • 0.6–1.4 equivalents, precisely measured to match the target molecular transformation and impurity cutoff limits; adjustments according to LC/MS-based monitoring of conversion efficiency in crude pesticide actives

    Downstream process integration

    • Fed to the secondary amide-forming condensation stage, following activation of the acid moiety, with traceability throughout crystallization and isolation of the active technical grade compound

    Final product types

    • Amide herbicide technical concentrates
    • Selectivity-enhanced pesticide active ingredients
    • Patent-enforced herbicidal intermediates for formulation usage

    3. Specialized Fine Chemical Synthesis

    In the fine chemicals sector, customers use our compound to construct designer amine-ketone – and further, imine-derived – monomers and specialty ligands for subsequent coatings, resins, and advanced materials applications. The reactive profile enhances the versatility in subsequent cyclization or functionalization steps. Regulatory adherence is required for export to major markets, so each use formulates according to purity, residual solvent limits, and trace contaminant specifications dictated by downstream advanced material standards.

    Industry compliance standards

    • ISO 9001:2015 for fine chemical manufacturing process control
    • OECD Test Guidelines (for environmental and chemical safety evaluation)
    • REACH substance registration and notification
    • Product-specific material grade requirements (e.g., electronic-grade or monomer-grade certification)

    Typical usage ratio

    • 1.0–1.5 equivalents relative to the key ring-closing or condensation substrate; ratio set to balance conversion yield, side-product minimization, and desired end-use monomer type

    Downstream process integration

    • Input at the amine-ketone condensation step, followed by downstream derivatization, polymerization, or coordination complex synthesis, based on end user’s custom specification

    Final product types

    • High-purity functional monomers
    • Advanced polymer building blocks
    • Custom ligands for metal chelation in specialty coatings and catalysts

    4. Pharmaceutical Impurity Reference Standards Manufacturing

    Producers of analytical and reference standards integrate our material for the synthesis, isolation, and certification of structurally related drug impurities or degradation products. Used at explicitly calculated, trace-level scales, it supports both regulatory submissions and in-house QC system development for pharmaceutical finished goods. Strict traceability, lot-specific documentation, and adherence to reference compound characterization protocols steer this application in response to global GMP and pharmacopoeia guidance.

    Industry compliance standards

    • USP Reference Standard production requirements
    • ICH Q3A/B (Impurities in New Drug Substances/Products)
    • ISO/IEC 17025 Laboratory Accreditation for reference material characterization
    • GMP Annex 11 for qualification of analytical reference material

    Typical usage ratio

    • Usually applied at 0.9–1.1 equivalents per target trace impurity synthesis batch, calculated based on the desired reference compound quantity and customer-provided structure validation method

    Downstream process integration

    • Direct input into targeted impurity synthesis, followed by preparative isolation, analytical characterization (NMR, MS), and batch certification per customer RM specification

    Final product types

    • Isolated impurity reference standards for regulatory filing
    • Pharmaceutical secondary standards for internal QC calibration
    • Pharmacopoeia-compliant stability study standards

    5. Research Reagent and Analytical Building Block Supply

    Academic and industrial R&D laboratories utilize our high-purity grade for exploring the synthesis of analogues, labeling studies, and targeted chemical library construction. Batch supply is supported by detailed analytical documentation, and shipments conform to institutional safety and chemical inventory controls. Procurement teams specify the necessary grade to match the requirements of advanced synthetic route development or assay validation work.

    Industry compliance standards

    • GLP (Good Laboratory Practice) as per OECD and FDA guidance for chemical supply to contract research organizations
    • Institutional chemical safety codes for laboratory reagents
    • GHS labeling and transport under UN Model Regulations
    • Product-specific MSDS and certificate of analysis aligned with university or institute protocol

    Typical usage ratio

    • Flexible; generally 0.5–2.0 equivalence depending on target molecule requirements, with user adjustment based on experimental synthetic design or structure–activity exploration protocols

    Downstream process integration

    • Supplemented at custom-defined steps in novel synthetic workflows, often as a precursor for analog generation, directed functionalization, or mechanism-of-action probe development

    Final product types

    • Custom research chemicals
    • Labeled intermediate compounds for SAR studies
    • Analytical probes and chemical biology toolkits
    Free Quote

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    Certification & Compliance
    More Introduction

    1-Dimethylamino-2-Methylpentan-3-One—Precision in Every Molecule

    Genuine Manufacturer’s Perspective on Quality, Consistency, and Application

    Our production lines run early each morning with clear intentions: deliver chemistry that speaks through precision, reliability, and transparent process. In this spirit, 1-Dimethylamino-2-Methylpentan-3-One stands out among our portfolio. Our expertise stretches back over decades of refining amines and ketones. Every batch tells a story about the way we select feedstocks, monitor reaction profiles, and scrutinize the outgoing quality metrics.

    1-Dimethylamino-2-Methylpentan-3-One, known in our internal documentation by its established chemical structure, represents a solution tuned to the demands of contemporary synthesis and applied chemistry. Those who have spent time in production know the headaches triggered by unpredictable intermediates or batches that vary from order to order. In a facility like ours, we lean into closed-loop controls and temperature staging, closely monitoring pressure profiles and solvent ratios so the output carries the fingerprint of robust process discipline. This isn’t just technical detail—lifelong chemists recognize the difference during routine analysis; peaks land where they should, purities trace their expected range, and storage remains manageable with typical demands for temperature and atmosphere.

    Built for Synthesis: Where Our Product Fits In

    The use of 1-Dimethylamino-2-Methylpentan-3-One carries wide appeal for those scaling up fine chemicals and moving through multi-step synthesis plans. In environments where process interruption can mean cascading losses—both in time and material—confidence starts at the molecular level. We cater to those who need more than stock catalogue options; feedback from labs and pilot plants shaped our specifications toward low residual water, clear GC traceability, and impurities that land below relevant thresholds with batch-to-batch predictability. These metrics rest on the backbone of decades-old SOPs that our staff refine and adapt as technologies shift and regulatory boundaries change.

    Practical teams have sent back stories describing how customary routes involving other N,N-dimethylaminoketones yielded process hiccups: separation challenges, unstable distillation fractions, or protracted drying steps. Our own adaptation to this knowledge brought us to invest in vacuum distillation hardware and in-line water scavenging, yielding a product free of lingering moisture and colored by transparency. This has translated into fewer post-processing steps in downstream lines, which helps lean teams maintain rapid throughput and high reliability on spec.

    Difference Rooted in Process—Not in Marketing

    In our corner of the industry, differences between products boil down not only to the chemical itself, but to its methodical preparation and consistent supply. Chemistry delivers its rewards only in the hands of those who marry solid process engineering with an eye for detail. We trace each bottle to a discrete production log, so chemists and operators track exactly what’s been delivered. Frequent users of 1-Dimethylamino-2-Methylpentan-3-One have learned that the point of differentiation comes with time: long-term customers know that one batch flows like the next, and revalidation cycles can slow down because the material character maintains its profile across fiscal quarters.

    Discussions with process managers consistently reach the issue of byproduct residues, particularly in the ever-challenging field of engaged synthesis. Working with this compound, we place effort into cleaning up extrusion points and implementing filtrations that pull metal residues and non-volatile organic traces well under limits. Unlike some alternative alkylaminoketones that can exhibit batch-to-batch volatility due to varied upstream sources, we anchor our raw materials to processes we’ve audited—and sometimes developed in collaboration with local feedstock partners. This isn’t a story of certifications or audits alone, but of real-world supply resilience when global trade lines become unpredictable.

    Specification: More Than a List—It’s an Operational Guarantee

    Most people looking for 1-Dimethylamino-2-Methylpentan-3-One will compare technical sheets, but in practice, data alone never tells the complete story. Every specification we outline stems from the actual plant floor analytics. Take water content as a case in point—our finished product typically reports below 0.1% moisture using Karl Fischer titration, a result that comes from low-pressure drying steps integrated after final distillation, rather than solely by chance or natural luck. The boiling point, often reported as 80-82°C under reduced pressure, remains tightly controlled, produced by monitoring pressure and fraction collection rather than trusting catalog values.

    Color, another sleeper metric for many, receives attention as well. We run UV traces and visual tests; our product presents as a clear, colorless liquid—one that holds its profile even after two months sealed with proper atmospheric controls. The amine value, determined by titration with standard acid, consistently aligns with the theoretical range, giving those in applied organic chemistry a comfortable window for further functionalization. More subtle indicators, such as low residual solvent content, not only satisfy tough downstream applications but effectively reduce off-target reactivity in more sensitive multistep syntheses.

    Real-World Usage: Feedback Grounded in Practice

    We listen closely to those putting our chemicals to work on actual shop floors. Whether it’s pharma scale-up labs, sophisticated research groups, or steady API manufacturers, the stories echo similar needs—reliable supply, unwavering purity, and support in unusual troubleshooting cases. One pilot customer built a process around 1-Dimethylamino-2-Methylpentan-3-One for an alkylation sequence, only to find a rival product led to inconsistent endpoint conversions. Our responses did not end with product substitution—we sent out in-process reference samples, supported by GC-MS overlays, so their analytical chemists could pin down minute differences and recalibrate confidently.

    We’ve observed the way knowledgeable researchers turn small yield inconsistencies into improvement opportunities. During a time of raw material tightness, some labs tested alternative providers and documented fatigue in saponification reactions arising from byproduct amides. Our own material, shipped with accompanying batch analytics, allowed their team to identify root causes fast—saving days spent on solvent exchanges or unplanned batch reworks. The mentions rarely make their way into glossy marketing files, but we take pride in running medium-scale tests in our own pilot reactors to validate real-world adaptability.

    Risk Management and Regulatory Considerations

    Stringent standards apply for 1-Dimethylamino-2-Methylpentan-3-One, both from regulatory bodies and practical safety sense. Decades of experience have cultivated a respect for the risks inherent in handling secondary and tertiary amines—flammability under certain vapor/air mixtures, reactivity with oxidizers, and the headache of low-level nitrogenous odorous byproducts if containment isn’t up to standard. Our facility runs regular process hazard reviews, ensuring that air handling, vapor recovery, and storage protocols match the hazard profiles described in our own training programs, rather than solely regulatory mandates.

    Customers—especially those in pharma and specialties—want clear answers about heavy metal levels, absence of specific organic contaminants, and traceability right back to the original feedstocks. In response, we don’t simply supply paper trails; our technical team supports on-site audits and shares access to analytical records. Inspection routines capture not only appearance and assay data, but unknown peaks on LC-MS—even when levels fall below accepted reporting thresholds. This focus translates into a smoother qualification process for those scaling to cGMP environments or other high-governance workflows.

    Supply Chain Resilience and Forward-Thinking Operations

    The last few years have tested every manufacturer’s grip on continuity. We have kept 1-Dimethylamino-2-Methylpentan-3-One accessible by running secondary supplier agreements for key precursors and recycling solvent streams wherever quality permits. Our mindset is simple—reduce exposure to logistic shutdowns and protect customers who need timed deliveries. Emergency runs out the door aren’t left to luck. Storage in controlled environments, process redundancy in distillation and purification lines, and staff cross-training mean orders keep flowing when market shocks ripple through global ports.

    The raw material market can send shockwaves through planning teams when feedstock prices or purity swings up or down. Our teams lock allocations by negotiating seasonally and occasionally support regional upstreams, even funding joint maintenance projects so that our own stocks aren’t tied to single pipelines. This is not about hedging for its own sake, but about keeping customers in the loop and inviting real conversations when price structures threaten stability. Our technical sales staff know that open communication makes for smoother project management and fewer unforeseen delays.

    Environmental Responsibility and Process Innovation

    Any facility with our longevity faces pressure to do more than recycle solvents or minimize off-gassing. We scrutinize waste streams routinely, running in-plant titrations and chromatography to catch minor impurities before they leave for waste treatment. In cases where process changes could reduce energy requirements—such as switching from classical distillation to thin-film evaporation—we prototype modifications and submit new batches to rigorous internal review. No production line changes unless we’re confident that quality, yield, and safety all trend positive.

    Markets paying attention to green chemistry have flagged amines, especially those built on petrochemical sources, as candidates for reformulation or route redesign. We maintain research ties with upstream biosynthesis groups and invest in lab-scale pilots for future feedstocks. The transition will take more than headlines, but in our house, every improvement—no matter how small—lands a little less waste and a little more resilience for everyone along the production chain.

    Supporting Customers, Enabling Scale-Up, and Earning Trust

    Relationships in chemical manufacturing develop across years: not every lot ships to a single end use and not every customer runs identical processes. Our technical team fields countless calls not just about ship dates, but about alternative purification ideas or route deviations based on changing science. The best part about working directly with users is watching as feedback cycles pull us into unexpected discoveries. Recent inquiries focused on scalability; the trick was addressing concerns tied to vapor management during scale-up, so we walked teams through empirical calculations, suggesting condensers and air flow tweaks suited to their rig—not just generic advice.

    Support here means more than a few reference papers; it carries into detailed impurity profiling and sharing the “cookbook” view of how our own operators train new staff to avoid routine pitfalls. This isn’t shared lightly—after the years invested in process tuning, every tip circling back improves not just yield, but long-term equipment cleanability and operational uptime. Customers uncover idiosyncrasies unique to their reactors or staffing schedules; we sometimes adapt shipping packs or suggest adjusted storage methods so their material arrives ready for seamless inclusion in their own workflow.

    Differences Matter: Insights from Our Own Shop Floor

    Competitors in this space may claim equivalence, but real-world production shows which product can be trusted through seasonal changes, staff rotations, and abrupt supply demands. Differences between suppliers lie in retention of consistency, openness to feedback, and transparency when things don’t run to plan. Over several decades, our best customers have grown alongside us. We sit through their audits, receive visits, and send our own technical leads out to see processes in action. Sometimes, it’s small improvements—a filtration tweak here, a better airlock process there—that adds up to a smoother campaign, a few percentage points in yield, or a batch run that doesn’t stall at 2 a.m. on a Friday.

    Despite sharing a common name, iterations of 1-Dimethylamino-2-Methylpentan-3-One vary globally in their practical outcomes. We choose not to depend on outside traders to verify compliance, but keep technical staff available for live troubleshooting. By keeping roots deep in both bench and plant chemistry, our results show up where it counts—in real assays, in happy plant operators reporting fewer alarms, and in the rare but vital moments when something unexpected turns up and a phone call brings practical solutions instead of a generic response.

    Conclusion: Chemistry Built on Accountability

    1-Dimethylamino-2-Methylpentan-3-One may look like just another chemical name to some, but for those who measure risk by the outcome of every production run, details matter. Our track record shows that investing in process discipline, open communication, and field-tested support pays off over every fiscal quarter and across product cycles. Every liter we produce carries not just technical compliance, but the legacy of experience, feedback, and continual process improvement earned from close-knit work with end users around the globe.