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1-Chloro-4H-Octafluorobutane

    • Product Name 1-Chloro-4H-Octafluorobutane
    • Alias FC-84
    • Einecs 206-982-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    957408

    Cas Number 375-12-4
    Molecular Formula C4ClF7
    Molar Mass 222.49 g/mol
    Iupac Name 1-chloro-1,1,2,2,3,3,4,4-octafluorobutane
    Appearance Colorless liquefied gas
    Boiling Point -4.5 °C
    Melting Point -105 °C
    Density 1.59 g/cm³ (at 20 °C)
    Solubility In Water Insoluble
    Vapor Pressure 2.2 atm (at 20 °C)

    As an accredited 1-Chloro-4H-Octafluorobutane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500g amber glass bottle with a secure cap, labeled "1-Chloro-4H-Octafluorobutane" and safety warnings in bold print.
    Shipping **Shipping Description for 1-Chloro-4H-Octafluorobutane:** Shipped as a compressed liquefied gas in approved high-pressure cylinders. Classified as a hazardous material (UN 2418). Store upright, away from heat, ignition sources, and incompatible substances. Ensure containers are properly labeled and secure during transit, complying with applicable DOT, IATA, and IMDG regulations for fluorinated halogenated hydrocarbons.
    Storage 1-Chloro-4H-octafluorobutane should be stored in a tightly sealed container away from incompatible substances such as strong oxidizers and bases. Keep it in a cool, dry, and well-ventilated area, away from direct sunlight and sources of ignition. Use appropriate chemical storage cabinets and maintain clear labeling. Personal protective equipment should be worn when handling the substance.
    Application of 1-Chloro-4H-Octafluorobutane

    Applications of 1-Chloro-4H-Octafluorobutane in Industrial Manufacturing

    1-Chloro-4H-Octafluorobutane serves as a specialty fluorinated intermediate and solvent across several advanced industrial fields requiring high chemical stability, selective reactivity, and low toxicity. As a direct manufacturer, we supply this material to established value chains within electronic, refrigeration, pharmaceutical, specialty polymer, and precision cleaning sectors, where rigorous processing and regulatory demands are standard.

    1. Electronics: Semiconductor Wet Etching and Cleaning

    Major logic and memory fabrication plants rely on perfluorinated solvents for advanced wafer etching, photoresist stripping, and equipment cleaning. The chemical’s high volatility and selectivity support residue-free processing at critical steps. Customers introduce our raw material at proprietary blend ratios, optimizing etch rates without corroding advanced lithography masks or patterning layers.

    Industry compliance standards

    • SEMI MS2 specification for solvent purity in semiconductor manufacturing
    • IEC 61340-5-1 standards for electrostatic discharge (ESD) controls in process environments
    • RoHS Directive (2011/65/EU) exemption compliance for persistent fluorinated process chemicals
    • ASTM D5127 for electronic grade water and solvent quality levels

    Typical usage ratio

    • 10%–35% by weight in custom aqueous or anhydrous etch blends, adjusted per wafer material chemistries and equipment design
    • 15%–30% in post-etch residue cleaning baths; end users adjust for the target removal profile

    Downstream process integration

    • Charged at the etch or clean module feed tank within front-end of line (FEOL) and back-end of line (BEOL) production
    • Used in recirculating cleaning/stripper baths in automated wet process tools

    Final product types

    • Advanced CMOS and DRAM chips
    • Display driver ICs
    • Compound semiconductor devices
    • 3D NAND and advanced logic circuits

    2. Refrigeration: Specialty Refrigerant Blending

    Manufacturers of low-temperature refrigeration equipment utilize 1-Chloro-4H-Octafluorobutane as a component in next-generation refrigerant blends. Its low GWP and strong chemical inertness help meet evolving international refrigerant protocols, balancing performance with regulatory phase-outs. Qualified formulators dose this additive for extended evaporator life and leak reduction, particularly in high-value cold chain and medical cooling assets.

    Industry compliance standards

    • ASHRAE Standard 34 and ISO 817 for refrigerant classification and safety groups
    • F-Gas Regulation (EU) No 517/2014 on controlling fluorinated greenhouse gases
    • UL 60335-2-40 compliance for safety in household and commercial refrigeration units
    • REACH registration status for fluorinated gaseous substances

    Typical usage ratio

    • 3%–15% by mass in blended HFC/HFO refrigerant mixtures; fine-tuned to system pressure and temperature envelope
    • Less than 10% for ultra-low temperature lab freezers to match viscosity and miscibility

    Downstream process integration

    • Charged during precision refrigerant filling on assembly line vacuum stations
    • Injected in field retrofits through service ports following compatibility validation

    Final product types

    • Industrial refrigeration and process chillers
    • Pharmaceutical cold storage systems
    • Precision laboratory freezers
    • Refrigerated transport containers

    3. Pharmaceutical Synthesis: Fluorinated Drug Intermediate

    API manufacturers integrate this fluorinated compound as a halogen source or intermediate scaffold during synthesis of high-value small molecule drugs. Its electron-rich structure enables regioselective modifications not possible with bulkier or less inert reagents, supporting the creation of improved bioavailable pharmaceutical actives. In GMP environments, operators strictly monitor quality and residual solvent content per drug master file requirements.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • USP–NF standards for residual solvent (Class 2) control
    • European Pharmacopoeia sections 2.4.24 (Volatile Impurities) and 5.2.8 (Elemental Impurities)
    • FDA 21 CFR Parts 210/211 for finished pharmaceutical production

    Typical usage ratio

    • 0.5–5 mol% as fluorination or chlorination reagent, depending on API synthetic route and substitution degree required
    • Occasionally up to 10% in intermediate steps where direct substitution efficiencies are low and complete removal is achievable post-reaction

    Downstream process integration

    • Added at charge preparation for stepwise synthesis in multi-reactor trains
    • Monitored for complete consumption and purged during downstream purification (distillation, chromatography)

    Final product types

    • Fluorinated anti-inflammatory agents
    • Oncology small molecule precursors
    • Respiratory and CNS active ingredients with improved metabolic profiles
    • Intermediate building blocks for further functionalization

    4. Specialty Polymers: Fluoropolymer Chain Modifier

    Producers of advanced engineering plastics and extrusion coatings utilize 1-Chloro-4H-Octafluorobutane as a chain transfer or end-capping agent to precisely tailor polymer architecture. Its unique halogen/fluorine balance enables incorporation at specific molecular termini, improving thermal stability, hydrophobicity, and surface inertness in applications where traditional modifiers lack stability or process compatibility.

    Industry compliance standards

    • ISO 9001-certified manufacturing/QC for batch traceability
    • ASTM D3307 for PTFE and related fluoropolymer specification
    • REACH Annex XVII for restricted substances in finished polymers
    • FDA 21 CFR 177.1550 for fluoropolymer food contact if applicable

    Typical usage ratio

    • 0.05%–1.0% by weight as a terminal group modifier
    • 0.2–0.8 mol% for highly branched or specialty end-functionalized fluoropolymers

    Downstream process integration

    • Dosed into polymerization reactors at the chain initiation or quenching stage
    • Monitored through in-process NMR and GC for conversion and integration rates

    Final product types

    • Fluoropolymer tubing and piping
    • High-performance cable insulation compounds
    • Extrusion coated films for corrosive environments
    • Ultra-thin hydrophobic membrane materials

    5. Precision Cleaning: High-Reliability Component Cleaning Fluids

    Top-tier aerospace and optics suppliers formulate precision cleaning agents including 1-Chloro-4H-Octafluorobutane for removal of particulates, organic residues, and ionic contaminants in oxygen- and moisture-sensitive assemblies. The combination of low surface tension and rapid evaporation supports non-contact drying of instrument and microelectromechanical parts without redeposition, minimizing costly rework and downtime in validated GMP and AS9100/ISO 13485 manufacturing spaces.

    Industry compliance standards

    • SAE AS9100 and ISO 13485 quality system requirements for aerospace and medical instrument cleaning
    • ANSI/AAMI ST108 guidance for automated cleaning solutions in device manufacturing
    • EPA TSCA compliance for perfluorinated environmental release controls
    • REACH SVHC reporting for PFAS content management

    Typical usage ratio

    • 20%–50% by weight in precision formulated cleaning blends
    • Component concentration determined by substrate material, contaminant profile, and automated system design

    Downstream process integration

    • Direct application in ultrasonic or vapor degreasing units
    • Integrated into closed-loop rinse and dry stations on cleanroom assembly lines

    Final product types

    • Aerospace gyroscope and navigation components
    • Precision medical instrument assemblies
    • High-purity optical sensors and laser optics
    • MEMS device subassemblies
    Free Quote

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    Certification & Compliance
    More Introduction

    1-Chloro-4H-Octafluorobutane: Practical Use and Distinct Advantages from the Manufacturer’s Bench

    Introducing a Reliable Fluorocarbon for Advanced Applications

    Our direct experience with 1-Chloro-4H-Octafluorobutane, commonly identified by its molecular structure C4ClF8, reaches back over a decade. Throughout the years, we have refined our process and deepened our understanding of where this specialty fluorinated solvent serves manufacturers best. The model we bring to the market meets high standards of purity, confirmed batch after batch with state-of-the-art gas chromatography and mass spectrometry. Different sectors—especially in electronics, specialty coatings, and refrigerants—seek this compound for the specific properties it brings to complicated processes.

    Understanding the Chemistry and Structure

    The unique arrangement of fluorine and chlorine atoms within 1-Chloro-4H-Octafluorobutane lends a particular set of physical and chemical characteristics. The presence of the chlorine atom shifts reactivity and volatility in ways that set it apart from its fully fluorinated cousins. As manufacturers, we have validated that introducing a chlorine atom within a perfluorinated backbone often tunes the boiling point and modifies solvent behavior. In reactor conditions, the compound maintains notable stability, standing up to many industrial stressors that would degrade lesser molecules.

    Application Experience: Where 1-Chloro-4H-Octafluorobutane Excels

    Electronics firms often prefer this molecule when handling sophisticated cleaning operations. Every lot leaving our facility has helped microelectronic plants remove trace contaminants from wafer surfaces or finished circuit boards. Organic residues, oils, and fine particulates lift away, which can help reduce defect rates during critical assembly. Results are consistent, because the physical properties remain reliable between batches.

    Some customers in precision optics depend on this molecule for effective rinsing without residue. Through ongoing dialogue with field engineers, we witnessed time and again how its low surface tension and efficient wetting foster complete coverage across intricate geometries. This makes it a strong option for manufacturers of lenses, fiber optic connectors, and laser assemblies.

    Where refrigerant blends demand enhanced safety—without sacrificing performance—1-Chloro-4H-Octafluorobutane occasionally serves as a key intermediate. Its boiling and condensation behavior fit certain engineering requirements, usually in advanced test scenarios, research, or proprietary blends.

    Handling and Practical Considerations

    We have stored and shipped metric tons of this compound, and have found it to be manageable under standard protocols for low molecular weight liquid fluorocarbons. While our R&D team evaluates stability under heat, ultraviolet exposure, and moisture, results repeatedly support robust performance. To guarantee end users receive unstressed product, we store and handle under dry, inert conditions, away from open flame or incompatible materials.

    Anecdotal field reports sometimes spark debate around compatibility. Direct consultations with customers guide safe adoption, especially when evaluating novel materials or when moving from legacy cleaning solvents. Our technical support crews respond to such feedback, running compatibility checks and providing real-world application insights rather than pure data-sheet theory.

    Strict quality controls, both on site and post-delivery, stand at the core of our operation. We often invite customers to review statistical quality control data. We also trace each drum or bulk container back to its production batch, providing transparency on specification adherence. This approach supports both environmental responsibility and material reliability.

    Distinction from Other Fluorocarbons

    Working hands-on with many fluorinated solvents over the years gives our team firsthand knowledge of how C4ClF8 differs from alternatives such as perfluorobutanes, perfluoropentanes, or perfluorohexanes. The most apparent distinction is the chlorine atom’s influence on thermophysical properties. In practice, this often translates to more adaptable boiling profiles and superior cleaning for a narrower band of soils and polymers. Manufacturers who once used fully fluorinated solvents are sometimes surprised by the performance edge in certain applications, especially where solubility and volatility make a difference.

    Comparing with widely used perfluorinated butanes, 1-Chloro-4H-Octafluorobutane often demonstrates enhanced solvent power against moderate-polarity contaminants and ionic residues. Perfluorocarbons lacking a halogen substituent sometimes miss that versatility in solvent behavior. Field feedback points not just to improved cleaning results, but also to greater reliability in downstream process stability, especially where rinse residues would otherwise compromise delicate assembly operations.

    From a regulatory compliance viewpoint, the incorporation of chlorine can make a clear difference in certain jurisdictions. Our technical compliance team remains abreast of ongoing environmental standards and restrictions, which sometimes affect allowable use cases. Owing to decades of accumulated data on reactivity, decomposition products, and documented exposure levels, we can confidently advise on responsible use within these evolving standards. This real-world environmental experience guides both plant-level recommendations and supply chain decisions.

    Insights from Continuous Production and Feedback

    Operating proprietary synthesis reactors gives us a unique window into the real-life challenges that commercial synthesis of C4ClF8 brings. Tightly managed reaction conditions and precise feedstock ratios ensure maximum yield and consistent characterization. Each product cycle produces data which, over the years, has helped us fine-tune both reaction kinetics and purification steps. We routinely share these improvements with loyal customers, helping them anticipate any subtle changes that may influence their own quality controls.

    Direct interaction with our worldwide customer base generates practical feedback about storage conditions, behavior in mixing tanks, and downstream recovery techniques. Some solvent systems behave predictably in a laboratory but fall short in an industrial setting. Because our staff lead training and host technical visits on-site, we receive not just outcomes but context—machine age, piping materials, and even regional humidity patterns all factor in to real-world application. This continual learning loop opens the door for process refinements both at our plant and on customer premises.

    From our vantage, resolving unforeseen process issues sometimes demands practical, on-the-floor problem solving over theory. A cleaning or rinsing line that clogs every 20 cycles, or a storage drum that emits more vapor than expected, leads to modifications in fill procedures, recommendations on venting, and tweaks to transport tank materials. Over the years, these incremental field-driven adjustments have built a reservoir of pragmatic knowledge—often more valuable than any datasheet or manual.

    Comparing Alternatives in Real Application Scenarios

    Many customers weigh 1-Chloro-4H-Octafluorobutane against the latest hydrofluoroolefins or newer proprietary solvent blends. Our experience working with blends and standalone products alike suggests that each fluorocarbon brings a blend of advantages and compromises. Some hydrofluoroolefins promise lower global warming potential, but they rarely match the combination of volatility, solvent power, and chemical inertness that C4ClF8 offers. The decision rarely turns on any single property: the right choice depends on equipment, required cleaning level, environmental priorities, and ROI.

    We regularly host joint trials: our R&D chemists and customer process engineers set up pilot lines for apples-to-apples comparison. More than once, our customers start with an alternate fluorinated solvent but circle back to C4ClF8 for its reliable operation and proven outcomes. Case studies including high-frequency electronics cleaning, optics manufacture, and even certain inertial sensor assembly lines keep confirming the predictable value of incorporating chlorinated fluorocarbons in specialized settings.

    Up-Close with Process Constraints

    Not all factories welcome solvent changes, so we invest time and care in helping process engineers pivot from legacy compounds to newer solutions. In our own facility, introducing any modified formulation means checking against system seals, metal compatibility, and vapor recovery. Workshops for plant operators and system maintenance teams reduce the learning curve and minimize plant disruption.

    Because heat, pressure fluctuation, and potentially static-prone environments all interact with halogenated fluorocarbons differently, we focus on direct dialogue with end users. For example, a solvent recommended for cold immersion cleaning in theory might show excessive evaporation loss at higher altitudes or in end-markets with drier climates. Our field representatives bring practical advice around local climate impacts on volatility and storage. A few simple adjustments—like enhanced vapor recovery or pressure-relief vessel upgrades—can stretch product longevity and uphold both safety and performance.

    Efficiency in Industrial Cleaning: A First-Hand Perspective

    In day-to-day operation, plant managers report smoother line flow when using C4ClF8-based cleaning protocols. Clean parts exit the rinse station without visible spotting or haze, which reduces failed QA checks. Over months and years, these details become the difference between steady output and batch-to-batch downtime.

    Surface cleaning benefits especially from the molecule’s combination of low viscosity and moderate boiling point. Operators note easy drainage from complex metal or plastic casings; less pooling means faster drying and reduced risk of chemical entrapment. This practical effect can become decisive in high-volume lines or when cleaning high-value, sensitive parts with tight tolerances.

    We kept notes over the years as automated optical inspection systems flagged fewer anomalies with C4ClF8-washed parts. Operators attribute this to the absence of fluorinated residues and the compound’s ability to lift mixed organic and inorganic particles. These hands-on wins translate into consistent product release and lower scrap rates, supporting both bottom lines and sustainability targets.

    Broader Environmental and Safety Insights

    Experience handling, transferring, and disposing of C4ClF8 has built a deep well of safety and environmental expertise in our workforce. We pursue best-practice containment to cut fugitive emissions; routine ambient air monitoring inside our facilities tracks real-world exposure. Any accidental releases are investigated and followed by procedural updates, which we openly share with industrial partners.

    Periodic engagement with regulators has taught us how the presence of both chlorine and multiple fluorines shapes the risk profile versus alternate solvent classes. While this class of compound does not fall under the strictest persistent organic pollutant listings, smart stewardship expects prudent handling, closed-system processing, and careful waste management. We partner with third-party recyclers to manage end-of-life material streams, aiming for resource recovery wherever possible.

    Health monitoring for operators directly working with the material forms part of our internal policy. By investing in personal exposure monitors and robust ventilation, we keep below established threshold limits in even the busiest handling environments. This real-world vigilance, more than any theoretical toxicology study, anchors our confidence in recommending large-scale industrial use.

    Continuous Improvement and Lessons Learned

    Rolling improvements have made our production line more energy efficient and boosted yields, a process steered by feedback from both our in-house chemists and our industrial customers. Systematic tracking of lot performance pinpoints issues before they ripple down to our clients. Once, an uptick in customer cleaning complaints prompted a deep dive into gas-phase impurities, leading to a fresh approach to nitrogen purging during bottling. These feedback loops matter more than any single laboratory result—they ground our process in lived reality rather than theoretical promise.

    Workshops with customer process engineers often spark ideas for process refinement. Cross-pollination of methods—like solvent recycling, tank purging, or even adjusted spray nozzle designs—generates downstream savings. Our plant holds periodic roundtables, inviting major customers to preview proposed process changes before rolling them out, aiming to keep everyone ahead of the technical curve.

    Looking to the Future: Confidence Built on Experience

    Having worked through both the growing pains and the triumphs of bringing 1-Chloro-4H-Octafluorobutane online, we have confidence in its role across a variety of manufacturing ecosystems. Investment in infrastructure, adherence to chemical stewardship principles, and a hands-on approach with end users have built a reliable base for both current and future applications.

    We will continue refining both process and product in response to field reports and emerging industrial needs. Ongoing dialogue with global partners and environmental agencies will keep us sharp, ready to adapt or pivot as new challenges or regulations come to light. Our years of direct production and on-site application support mean that both established customers and newcomers can count on a grounded, real-world perspective—rooted in production, proven in practice.