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1-Chloro-2-Ethylbenzene

    • Product Name 1-Chloro-2-Ethylbenzene
    • Alias 1-chloro-2-ethylbenzene
    • Einecs 202-634-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    586978

    Chemical Name 1-Chloro-2-ethylbenzene
    Cas Number 611-13-2
    Molecular Formula C8H9Cl
    Molecular Weight 140.61 g/mol
    Appearance Colorless liquid
    Boiling Point 195-197 °C
    Melting Point -39 °C
    Density 1.04 g/cm³
    Refractive Index 1.537
    Flash Point 78 °C
    Solubility In Water Insoluble
    Pubchem Cid 12110

    As an accredited 1-Chloro-2-Ethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 250 mL of 1-Chloro-2-Ethylbenzene, labeled with hazard warnings, chemical identification, and handling instructions.
    Shipping **Shipping Description for 1-Chloro-2-Ethylbenzene:** 1-Chloro-2-Ethylbenzene should be shipped in tightly sealed containers, protected from heat, sparks, and open flames. Transport must comply with local, national, and international regulations for flammable liquids. Properly label and package the chemical to prevent leaks and ensure safety during transit. Store upright in a well-ventilated area.
    Storage Store **1-Chloro-2-ethylbenzene** in a cool, dry, well-ventilated area away from sources of ignition, heat, and incompatible substances such as strong oxidizers. Keep the container tightly closed and properly labeled. Protect from direct sunlight and moisture. Use appropriate chemical-resistant containers. Ensure secondary containment to prevent leaks or spills and follow all relevant safety and regulatory guidelines for storage.
    Application of 1-Chloro-2-Ethylbenzene

    Applications of 1-Chloro-2-Ethylbenzene in Industrial Manufacturing

    As a specialist manufacturer, we supply 1-Chloro-2-Ethylbenzene for several core industrial sectors, each requiring specific purity, processing steps, and compliance protocols. Below are the four major downstream applications our clients use this raw material for. Each application scenario includes sector-specific compliance, recommended usage ratios, production integration details, and typical finished products from real-world downstream manufacturing routes.

    1. Intermediate for Agrochemical Synthesis

    In the agrochemical sector, 1-Chloro-2-Ethylbenzene serves as an essential intermediate for synthesizing certain herbicide and insecticide precursors. Downstream manufacturers rely on its high selectivity in alkylation and halogenation reactions, which form part of multi-step syntheses for active compounds. Accurate formulation during the early processing stage is essential for ensuring consistent conversion rates and product quality across large production batches.

    Industry compliance standards

    • ISO 9001:2015 for quality management in chemicals manufacturing.
    • REACH Registration (EU) concerning raw material traceability and handling.
    • US EPA regulations for pesticide intermediates (40 CFR 158.2000).
    • China GB 2763 for maximum residue levels in agrochemical products.

    Typical usage ratio

    • Dosage generally ranges from 0.8 to 1.2 molar equivalents in active ingredient precursor synthesis.
    • Ratio adjustment depends on side-chain length and required substitution degree of target molecules.

    Downstream process integration

    • Material enters the synthesis train following initial aromatic activation and functions as an electrophile in Friedel-Crafts reactions.
    • Often used in the first or second step of multi-stage agrochemical synthesis before further functionalization or ring-closing procedures.

    Final product types

    • Herbicide technical concentrates (e.g., substituted chlorobenzenes, phenoxy herbicides pre-cursors).
    • Insecticide intermediate compounds.
    • Plant growth regulator intermediates.
    • Bulk intermediates for downstream fine chemical formulation.

    2. Precursor for Pharmaceutical Intermediates

    Pharmaceutical companies source 1-Chloro-2-Ethylbenzene to manufacture specialty intermediates for API (Active Pharmaceutical Ingredient) synthesis, particularly for non-steroidal anti-inflammatory and anti-allergy drugs. Strict impurity control and lot-to-lot traceability are critical, as most processes involve subsequent nitration or amination steps where the ethyl and chloro substituents increase selectivity and reaction efficiency.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP) under ICH Q7A.
    • USP-NF and Ph. Eur. monographs for pharmaceutical-grade intermediates.
    • FDA 21 CFR Part 211 for process validation.
    • ICH Q3A-B for impurity control in APIs.

    Typical usage ratio

    • Used at 1.0 to 1.5 molar equivalents, adjusted for reaction yield and downstream coupling efficiency.
    • Exact amounts calibrated based on process scale (batch vs. continuous) and intermediate specification.

    Downstream process integration

    • Material is introduced during early-stage aromatic substitution, leading to directed ortho- or para-functionalization.
    • Frequently distilled before use to minimize residual impurities for sensitive pharmaceutical synthesis.

    Final product types

    • API intermediates for over-the-counter pain relievers.
    • Precursor compounds for antihistamine ingredients.
    • Building blocks for custom pharmaceutical synthesis (contract manufacturing).
    • Key intermediates for non-active ingredients (pharma excipients).

    3. Raw Material for Performance Polymer Production

    Producers of specialty polymers and engineering plastics incorporate 1-Chloro-2-Ethylbenzene into their process trains as a monomer modifier or as a precursor for functionalized comonomers. The compound enables targeted modification of polymer architecture, particularly in specialty resins where controlled halogenation improves fire retardancy, chemical resistance, and mechanical properties. Integration requires careful monitoring of addition rates and reaction conditions to ensure polymer chain uniformity and low residual monomer content.

    Industry compliance standards

    • ISO 14001:2015 for environmental management in plastics production.
    • UL 94 for flame retardancy of polymer products.
    • RoHS Directive (EU) on hazardous substances in electronic polymers.
    • ASTM D638 for tensile testing of plastics containing modified aromatic units.

    Typical usage ratio

    • Typical feed content ranges from 2% to 10% by weight in copolymerization; content adjusted according to fire retardant requirements and polymer type.
    • Lower ratios for bulk engineering plastics, higher for specialty high-performance resins.

    Downstream process integration

    • Material introduced during the reactive extrusion or pre-polymerization step.
    • Undergoes thermal or catalytic polymerization, joining with main monomers (e.g., styrenics, acrylates) to form modified copolymers.

    Final product types

    • High-performance engineering plastics with flame-retardant properties.
    • Copolymer resins for automotive and electrical housings.
    • Specialty packaging films with enhanced chemical resistance.
    • Composite resin systems for industrial tooling and electronics encapsulation.

    4. Component in Liquid Crystal Manufacturing

    Electronics and display device manufacturers use 1-Chloro-2-Ethylbenzene as a specialty intermediate in synthesizing specific liquid crystal (LC) monomers and mesogens, essential for advanced LCD screen production. Its unique halogenated aromatic structure facilitates the precise tuning of dielectric anisotropy and viscosity in final LC fluid. Process parameters such as reaction temperature, purification cycles, and solvent selection directly impact the purity and stability of the end product used in high-resolution panels.

    Industry compliance standards

    • IEC 61249 Part 2 for materials used in printed circuit boards and electrical insulation.
    • ISO 9001:2015 quality systems specific to electronics chemicals.
    • Cleanroom ISO Class 6 or better for LC and display production.
    • Japanese Industrial Standard JIS C 61225 for liquid crystal materials.

    Typical usage ratio

    • Content ranges from 1% to 5% by weight, depending on required LC phase behavior and end-product pixel tuning.
    • Adjusted for specific display technology (TV, mobile, medical devices).

    Downstream process integration

    • Enters the LC synthesis during precursor coupling or halogenation stage, ahead of purification and final blending.
    • Purity control essential prior to integration into LC mixtures for panel fabrication.

    Final product types

    • Twisted-nematic and IPS liquid crystal fluids.
    • High-contrast TFT-LCD screens.
    • Medical imaging panels.
    • High-stability LC blends for industrial sensor applications.
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    Certification & Compliance
    More Introduction

    Introducing 1-Chloro-2-Ethylbenzene: A Practical Perspective from the Manufacturer’s Workshop

    Direct Experience with 1-Chloro-2-Ethylbenzene in Modern Industry

    Experience shapes our approach to every product we make, and 1-Chloro-2-Ethylbenzene stands out as one of the most frequently requested intermediates for specialty organic synthesis. Over years of handling this compound, we have dealt with its quirks and strengths firsthand. As a manufacturer that oversees everything from reaction vessels to quality control, our focus remains squarely on maintaining consistent purity lot after lot. The distinct aroma from the production line unmistakably reminds us of its unique chemical backbone, pairing a chlorine atom with an ethyl chain on a benzene ring.

    At its core, 1-Chloro-2-Ethylbenzene is a staple for making complex chemicals that do more than sit on a shelf. Most of the time, our colleagues in the lab are preparing it for agrochemical or pharmaceutical use because its structure offers a reliable starting point. The meta relationship between the chlorine and ethyl groups introduces an edge for reactivity, making it a sought-after building block for several downstream specialties.

    Realities of Manufacturing and the Nuances in Production

    No batch of 1-Chloro-2-Ethylbenzene feels entirely routine. Manufacturing starts with the right grade of o-ethylbenzene, using chlorination processes that demand careful balancing of reaction temperature, feed rates, and agitation. Skipping small details here causes downstream headaches, whether through excess byproducts or reduced selectivity. Rigorous monitoring, using gas chromatography and mass spectrometry, keeps us ahead of impurities that typically lurk beneath the surface. Each run brings its set of adjustments, guided by routine titrations and calibration curves built from years of lab notes.

    Customers often ask why the material from a true source factory carries a different profile than a generic batch. To anyone who makes this compound for a living, the answer looks simple: process experience. Issues like trace polychlorination or ring chlorination byproducts get more manageable as techniques improve, so every kilo that leaves the plant meets the mark on specification sheets. Years of incremental tweaks set us apart from those simply repackaging bulk drums.

    Product Details and Specifications Tailored through Practical Knowledge

    People working with real substances know specifications matter more when they relate to application. The 1-Chloro-2-Ethylbenzene we ship out usually boasts purity higher than 99%, verified by repeated chromatographic checks. Remaining impurities largely consist of trace isomers or minimal monochlorinated aromatics — nothing slips through unless it meets our agreed shoulder peaks in analytical spectra. Visual inspection remains standard, with a colorless to pale yellow liquid in cleared glass bottles. Density, boiling range, and refractive index get checked against benchmarks established from archived production logs, not simply textbook values.

    Most customers choose drum or tank packaging, though specialized requests arise for lined steel containers when longer storage stability proves useful. Volatility and odor indicate safe handling, so proper labeling remains essential on every unit. Over decades, these hands have filled enough drums to know that batch-to-batch consistency makes all the difference in final product performance.

    Downstream Uses and Application Experience Shared

    From one production cycle to the next, we see 1-Chloro-2-Ethylbenzene heading mainly toward chemical synthesis — particularly for intermediates that build up bigger molecular frameworks. Research teams use it to prepare herbicide scaffolds and pre-cursors in pharmaceutical labs, relying on its consistent reactivity for clean transformations. Other clients demand this compound for specialty resins and modified polymers, taking advantage of its substitution pattern to tailor end-use properties.

    We’ve even partnered with research groups working on new specialty monomers, shipping out test batches for pilot-scale copolymerization. Its particular ring substitution provides points of attachment for further derivatization—an aspect often overlooked by distributors who focus purely on delivering a drum and moving on.

    Distinguishing 1-Chloro-2-Ethylbenzene from Other Aromatic Halides

    It’s common for buyers and researchers to ask how 1-Chloro-2-Ethylbenzene stacks up against other chlorinated benzenes. In our shop, we see its ortho-ethyl placement offering distinct reactivity differences compared with, say, para- or meta- isomers or even the more common monochlorotoluenes. The ethyl group directly adjacent to the chlorine shifts electron density, subtly affecting substitution rates and selectivity in electrophilic aromatic reactions.

    Beyond lab theory, real-life results support this distinction. Stepwise substitution, coupling, or oxidation reactions using 1-Chloro-2-Ethylbenzene exhibit improved yields with reduced side reactions, especially when compared with 1-chloro-4-ethylbenzene or simple chlorobenzene derivatives. This gives downstream chemists an edge — especially those developing proprietary molecules where minor yield improvements scale up to major cost savings over time.

    Another practical difference emerges during purification. Its boiling point and solubility profile, shaped by the ethyl group's sterics and electronics, aid in selective distillation and extractions. We’ve refined techniques for quick fractionation based on these parameters, minimizing the footprint of energy use and solvent waste. These are the things a manufacturer learns when handling thousands of liters, not reading a catalog.

    Quality Control: More than a Checklist

    Modern chemical manufacturing lives and dies by tight quality programs. The rough hands and attentive eyes on our production floor see more than numbers on a screen — they notice everything from slightly off odors to residue left by a hastily cleaned kettle. Every batch of 1-Chloro-2-Ethylbenzene runs through a series of validations, using reference standards traced back years. Our analysts have built a collection of spectral fingerprints unique to each product family, helping spot second-order impurities not always obvious by standard tests.

    We see requests from specialty customers for tailored impurity profiles. Custom synthesis houses or innovation labs often want less of certain isomeric byproducts, especially in pharmaceutical research. That means extra filtration steps or customized refining, blending mechanical work with sharp chemical insights collected on the job. As one of the few producers willing to modify SAP processes for select clients, we have learned that constant adjustment keeps us relevant, even as global standards move toward stricter thresholds year after year.

    Sustainability and Handling: Dilemmas and Solutions

    Handling chlorinated aromatics like 1-Chloro-2-Ethylbenzene brings real environmental responsibilities. The shift toward greener business means every flask and drum gets treated with care, from raw material sourcing all the way to waste management. Our plant tracks effluents down to parts per million, using closed-loop scrubbers designed after plenty of trial and error. Instead of letting minor leaks become routine, we built checklists that flag recurring faults before they threaten compliance.

    Recycling remains a constant goal. Any off-spec product gets rerouted through solvent recovery units or blended into fuel for in-house heat needs. We work with local authorities and environmental agencies to keep waste records transparent, offering full traceability whenever a customer requests backtracking on a shipment. Taking shortcuts on hazardous material control leads to regulatory trouble and headaches for end-users, so our policy stays clear: trace everything, treat waste as a resource not a nuisance, and inform downstream partners about sustainable practices.

    Continuous Process Improvement: Why We Innovate from the Shop Floor

    Innovation for us starts on the production line, not in marketing memos. Each inefficiency in making 1-Chloro-2-Ethylbenzene gets flagged by the team closest to the process. Sometimes a subtle switch in agitation speed, catalyst dosing, or washing temperatures unlocks more yield with less rework. Other times it’s about personnel training: experienced operators pass along tricks missed in formal documentation, honing the intuition for “what clean should look and smell like.”

    Catalyst life extension offers one recent success. By monitoring deactivation rates across multiple cycles, we devised a regeneration protocol using a proprietary wash sequence. This move alone pushed collective uptime up by nearly 7% over the last year at steady state. Others talked about going digital; our tech team built a custom dashboard showing real-time gas flow variability, catching anomalous spikes before batch quality drifted.

    These lessons go back into our supplier evaluations and R&D, shaping decisions about which grades of raw aromatics to source. When suppliers change a grade of ethylbenzene feedstock, we test before signing anything. Data from these runs becomes the baseline for each new shipment, helping us avoid downstream surprises for years to come.

    Traceability in Practice: Lessons from the Batch Log

    Track and trace work better with lived experience tied to each drum and batch sheet. Our team matches every unit of 1-Chloro-2-Ethylbenzene by production window, operator initials, and instrument log. Customers sometimes recall products when an issue pops up in a faraway lab. Pulling the right records in minutes — batch logs, GC plots, ambient storage conditions — gives both us and our clients peace of mind. This ready access to audit trails also speeds up compliance work.

    Not long ago, a partner flagged inconsistent reactivity from a lot received six months prior. Our review showed minor shifts in impurity fractionation, traced back to a temporary bump in reactor temperature when a sensor needed calibration. Fixing that oversight led to improved Poka-Yoke procedures for automated controls, strengthening every batch that followed. Not every failure story gets reported, but those who make chemicals for a living know that each solved issue leaves the process stronger for the future.

    Collaboration and Trust: Frontline Experience over Brochures

    Customers want more than a spec sheet. Chemists, procurement teams, and process engineers drop by to audit our facilities, observe a shift in real time, or ask if we have tried alternate syntheses. We believe transparency builds trust, so the shop floor stays open to partners who bring us practical problems in need of resolution. More than once, direct customer feedback prompted us to tweak drying schedules, tweak filling pressures, or revise test regimes to fit a downstream need.

    That hands-on interaction pays off. One instance saw a custom polymer developer needing tighter controls on sulfur content. Our team pulled unopened shipments, ran extra ICP-MS scans, and traced a supplier shift to a single week’s lot. Rather than lose a customer or send apologies, our technical liaison coordinated a solution — swapping out suspect feedstock and running extra pilot-scale tests until confidence returned to both sides.

    Scalability and Consistency: The Long View from Production

    Scalability means understanding how a process handles pressures from pilot drum to full-scale output. Manufacturing large lots of 1-Chloro-2-Ethylbenzene means pressure control, consistent reagent aging, and storage logistics all show new wrinkles at volume. Drum handling, in particular, becomes an art: temperature swings or careless stacking lead to leaks, discoloration, or problematic phase separation. Standard operating routines, handwritten logs, and unflinching operator training keep those issues rare, but only because years of vigilance shaped every protocol.

    Shipping quality at volume rewards meticulous record-keeping. Before each loading session, our warehouse crew double checks every closure and confirms dock temperature against seasonal fluctuation patterns tracked over decades. Investing in temperature-monitored storage for high-demand periods slashed the rejected batches during summer months to near zero. Long-term volume customers give candid feedback, helping us reinforce these habits and pursue yet more incremental improvements.

    Knowledge Transfer: Passing the Baton to the Next Generation

    As the faces change on the shop floor and in the control room, old hands pass along the lessons built batch by batch. No amount of written documentation replaces what comes from years spent blending, sampling, and correcting courses. Operators teach apprentices how a finished lot should look, pour, and smell — lessons learned only after handling thousands of drums. Training cycles reinforce this through hands-on rotation, where junior staff blend directly under supervision before signing off on any shipment.

    This tradition keeps our 1-Chloro-2-Ethylbenzene process robust, minimizing scrap, and supporting future innovation. Routine doesn’t mean complacency — every shipment is the result of thousands of small, careful habits. Apprenticeship and open problem-solving ensure the next generation can keep pace as customer requirements change and global standards rise.

    What Sets Manufacturer Quality Apart

    Firsthand manufacturing experience remains the difference between true chemical makers and generic product handlers. We face equipment failures, fluctuating raw stock, and trailing impurities each season. Instead of shipping catalog descriptions, we guarantee consistency batch after batch because the process was built, refined, and run by those who know it best. Each bottle and drum leaving our site reflects this commitment — shaped by real production insight, not marketing prose.

    Our journey with 1-Chloro-2-Ethylbenzene hasn’t been without challenges. Supply chain disruptions, regulatory tightening, and shifting end-use applications keep us adapting. Success rests not at the point of sale, but in the quiet, cumulative improvements strung across years of steady production and transparent partnerships. We trust chemistry — and those who make it — to deliver more than just a product number.