Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

1-Chloro-2,2-Dimethylpropane

    • Product Name 1-Chloro-2,2-Dimethylpropane
    • Alias Neopentyl chloride
    • Einecs 211-659-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    976403

    Iupac Name 1-Chloro-2,2-dimethylpropane
    Molecular Formula C5H11Cl
    Molar Mass 106.59 g/mol
    Cas Number 594-36-5
    Appearance Colorless liquid
    Boiling Point 85-87°C
    Melting Point -100°C
    Density 0.865 g/cm³
    Refractive Index 1.401
    Flash Point -1°C
    Solubility In Water Insoluble
    Vapor Pressure 128 mmHg (20°C)
    Smiles CC(C)(C)CCl

    As an accredited 1-Chloro-2,2-Dimethylpropane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1-Chloro-2,2-Dimethylpropane is supplied in a 250 mL amber glass bottle with a secure screw cap and hazard labeling.
    Shipping 1-Chloro-2,2-Dimethylpropane is shipped as a hazardous material. Ensure the container is tightly sealed, properly labeled, and protected from heat, sparks, and open flames. Transportation must comply with local, national, and international regulations, including proper documentation. Always use suitable secondary containment and chemical-resistant packaging to prevent leaks or spills during transit.
    Storage Store 1-Chloro-2,2-dimethylpropane in a cool, dry, and well-ventilated area away from heat sources, open flames, and direct sunlight. Keep the container tightly closed and properly labeled. Separate from oxidizing agents, acids, and bases. Use approved, chemical-resistant storage containers. Ensure spill containment is in place and follow all applicable safety regulations for flammable and volatile organic chemicals.
    Application of 1-Chloro-2,2-Dimethylpropane

    Applications of 1-Chloro-2,2-Dimethylpropane in Industrial Manufacturing

    As a dedicated manufacturer of 1-Chloro-2,2-Dimethylpropane, we are committed to supplying high-purity material that enables precise, compliant, and scalable production for industry leaders across core chemical sectors. Below, we detail the main industrial application scenarios where our experience in quality control and formulation support directly serves downstream innovators and large-scale processors.

    1. Bulk Pharmaceutical Intermediate Synthesis

    In pharmaceutical manufacturing, 1-Chloro-2,2-Dimethylpropane acts as an alkylating agent for the preparation of key intermediates, particularly in the synthesis of branched-chain compounds used in approved API pathways. Downstream plants integrate this raw material in a controlled environment to ensure traceability and batch consistency for high-value intermediates entering regulated drug supply chains. Our product maintains reactivity and minimal residuals, supporting compliance and yield in scale-up campaigns.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (EP) & United States Pharmacopeia (USP) monographs on intermediates
    • 21 CFR Part 210/211 (FDA cGMP)
    • REACH Annex XVII (Europe, hazardous substance restrictions)

    Typical usage ratio

    • 0.8%–3.5% w/w relative to main substrate, adjusted by desired substitution and impurity control; the precise loading depends on stoichiometric excess required to drive the reaction and downstream API impurity thresholds.

    Downstream process integration

    • Material charged directly to alkylation step reactors after solvent charging and temperature stabilization; monitored via in-process HPLC for completeness; followed by aqueous workup, phase separation, and purification.

    Final product types

    • API precursors for cardiovascular and CNS drugs
    • Branched-chain synthetic building blocks
    • Non-sterile pharmaceutical intermediates for further downstream transformations

    2. Agrochemical Fine Synthesis (Herbicide and Pesticide Intermediates)

    Agrichemical synthesis facilities utilize high-purity 1-Chloro-2,2-Dimethylpropane to introduce branched alkyl moieties into active molecules, improving biological activity and field performance in selected herbicide and insecticide active ingredients. We supply batch-certified raw materials that meet sector-specific residue and purity standards, supporting batch scale, cost-effective production in controlled reaction environments with predictable conversion and manageable byproduct profiles.

    Industry compliance standards

    • FAO/WHO Technical Specifications for Pesticides
    • ISO 9001:2015 Quality Management Systems in agrochemical production
    • Globally Harmonized System (GHS) for hazard classification
    • China’s GB2763 Maximum Residue Limits for Pesticides

    Typical usage ratio

    • 1.2%–4% w/w, set depending on target molecule structure, the efficiency of alkylation, and target purity requirements; excess commonly used to ensure complete conversion in batch reactions.

    Downstream process integration

    • Raw material is dosed to closed glass-lined reactors after charge of active core and solvent; addition managed via automated dosing systems; post-reaction, intermediate extracted, neutralized, and transferred for isolation.

    Final product types

    • Herbicide pre-cursor intermediates
    • Insecticide synthesis intermediates
    • Branched alkyl-substituted active ingredient bases

    3. Specialty Chemical Additive Manufacturing (Flame Retardants)

    Producers of specialty flame retardant additives incorporate this material as a key functional group donor in the synthesis of novel alkyl halo-derivatives that meet fire testing protocols for construction and automotive plastics. By providing consistent material properties and supporting documentation, we enable downstream manufacturers to align additive performance with evolving international flammability and migration standards, with process knowledge for blending and downstream resin adaptation.

    Industry compliance standards

    • UL 94 (Tests for Flammability of Plastic Materials)
    • REACH Regulation (EC) No 1907/2006 for chemical safety
    • RoHS Directive (2011/65/EU) on hazardous substances in electrical applications
    • ISO 178 (Determination of flexural properties of plastics)

    Typical usage ratio

    • 0.5%–2.1% w/w within additive synthesis batch, precisely dosed to achieve required halogen content and maintain compatibility in polyolefin blends; ratio tailored based on polymer substrate and desired flame retardancy class.

    Downstream process integration

    • Fed to synthesis reactors for precursor alkyl halide formation, then integrated in melt blending or compounding units; final additive dispersed in resin matrix prior to extrusion or molding.

    Final product types

    • Polyolefin-compatible flame retardant masterbatches
    • Chlorinated additive concentrates for cable sheathing
    • Modified flame retardant fillers for construction polymers

    4. Custom Alkyl Halide Building Block Production

    Fine chemical manufacturers use our material as a key building block for synthesizing branched-chain alkyl halides, which are then further functionalized for industrial lubricants, surfactant bases, or reactive intermediates in high-performance polymers. Raw material purity, low moisture, and consistent assay enable reliable scale-up and minimize downstream purification requirements, helping our customers meet advanced specifications for their specialty portfolios.

    Industry compliance standards

    • ISO 9001:2015 for process manufacturing QA
    • Responsible Care® Environmental Stewardship
    • UN GHS chemical labeling for workplace safety
    • EU CLP Regulation (EC) No 1272/2008 chemical classification

    Typical usage ratio

    • 1.5%–3.0% w/w per reaction batch, depending on targeted alkyl chain length and overall halogen incorporation; processed under inert atmosphere to prevent unwanted side reactions.

    Downstream process integration

    • Dosed as first or second reagent post-solvent charging, with real-time gravimetric or volumetric monitoring; follows with temperature-controlled nucleophilic substitution, workup, and column purification stages.

    Final product types

    • Intermediate branched alkyl halides for custom syntheses
    • Base stocks for specialty functionalized lubricants
    • Reactive monomers for advanced polymerization

    5. Organic Synthesis R&D and Scale-Up (Process Research)

    Process R&D institutions and contract manufacturers purchase our high-purity grades for optimizing new reaction routes, particularly for exploring unique steric profiles in alkylated products. The raw material’s defined impurity spectrum supports kinetic studies and pilot-scale campaigns, where research teams document reagent effect on reaction selectivity and scalability prior to phase transfer into commercial plants.

    Industry compliance standards

    • ISO/IEC 17025: General requirements for laboratory competence
    • OECD GLP Principles for non-clinical laboratory studies
    • REACH lab use exemption documentation
    • Company-specific SOP qualification records

    Typical usage ratio

    • 0.2%–2.0% w/w in small-scale batch, scale-up based on experimental objectives, with adjustment for substrate structure and targeted reaction pathway.

    Downstream process integration

    • Added under nitrogen or argon in jacketed glass reactors; employed in various alkylation, halogenation, or substitution protocols; analyzed by NMR, GC-MS for structure determination post-reaction.

    Final product types

    • Reference standards, analytics samples
    • Experimental intermediates for new molecule libraries
    • Pilot-scale demonstration batches for further scale-up
    Free Quote

    Competitive 1-Chloro-2,2-Dimethylpropane prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing 1-Chloro-2,2-Dimethylpropane: A Practical Approach from the Factory Floor

    What 1-Chloro-2,2-Dimethylpropane Represents in Everyday Chemical Manufacturing

    From a manufacturer's standpoint, 1-Chloro-2,2-Dimethylpropane has carved out a reliable spot in the landscape of alkyl chlorides. Every batch that leaves our reactors goes through a process shaped by hands-on experience with equipment, raw material fluctuations, and evolving expectations from customers in research and industry. The molecular structure, based on the isobutane skeleton with a chlorine atom branching off the main chain, brings a unique set of reactivity and handling factors. We often refer to it by its CAS number, 594-36-5, among operators in the plant—this shorthand saves time and draws a clear line between it and lookalike chemicals that can hardly substitute for one another in critical applications.

    Refining Consistency: Experience-Driven Production and Quality

    On our production line, everything starts with sourcing clean feedstock. Over the years, we have learned to watch for impurities in starting alcohols, which affect yield and purity further down the line. During chlorination, temperature and stir rates determine the extent of side products like polychlorinated derivatives. Tight control at this step means less work screening and purifying the final product. Experienced operators see subtle shifts in color or odor that instruments sometimes miss but have real effects on downstream performance.

    Quality control doesn’t stop at the analyzer. Just last quarter, a barrel flagged for off-odor was traced back to a cable insulation issue that introduced trace organics; addressing that issue strengthened our trust in every test result since. Standard specs for 1-Chloro-2,2-Dimethylpropane usually call for content above 99%. Water and acidity, although present in small amounts, get a hard look for anyone planning to use this compound in reactions sensitive to moisture or contaminants. Real-world practice means we focus just as much on how we fill, seal, and store—any slack here can cause quality slips that analytical results won’t catch until much later.

    Comparing 1-Chloro-2,2-Dimethylpropane to Other Alkyl Chlorides in the Lab and Plant

    For experienced users in chemical synthesis, differences among alkyl halides shape which product ends up on the bench or production line. Compared with 2-Chloropropane or n-Butyl chloride, 1-Chloro-2,2-Dimethylpropane brings extra bulk at the reactive center. This branching limits rearrangement reactions and influences physical behavior. The boiling point sits comfortably above lighter chlorides but steers clear of the fuss that comes with lengthy chains. Some customers come to us after struggling with inconsistent outcomes from secondary or primary chlorides, only to find that this compound’s structure builds more predictable results in certain alkylation or substitution reactions.

    Solubility can be a deciding factor too. 1-Chloro-2,2-Dimethylpropane dissolves well in common organic solvents but resists water, which means less scrambling to dry glassware or chase after dried solvents. In practice, this reduces downtime and improves yield consistency over multiple syntheses, especially on scale. Its stability against unintended dehydrohalogenation adds a layer of certainty. Those who tried gamma-irradiation or photolysis in their processes found fewer unwanted rearrangements compared to other isomeric forms.

    We see patterns in customer orders as well—electronic material manufacturers often reach for 1-Chloro-2,2-Dimethylpropane over less hindered options. For some, chlorine position in the molecule makes all the difference when building complex intermediates for agrochemicals or pharmaceuticals. This isn’t something that comes through just reading specs; it comes from feedback and troubleshooting across many seasons.

    End-Use Considerations: Practical Observations from Years in the Business

    In our own plant’s R&D work, 1-Chloro-2,2-Dimethylpropane serves well as an alkylating agent. Its mood in the flask—by which lab hands mean its reactivity profile under various conditions—favors certain nucleophiles without excessive byproduct formation. Classical methods like Williamson ether synthesis, or its application in Friedel-Crafts systems, benefit from the compound’s hindered nature. We’ve seen repeated success in producing highly branched ethers and esters that struggle for yield with slimmer alkyl chlorides.

    Colleagues in allied industries found that resin production, particularly for specialty adhesives and coatings, improved in batch reproducibility when switching to this compound. Its boiling range lets it evaporate at a predictable rate, which reduces inventory headaches and surprises in solvent balance after long transits. In our own storage, we’ve noted its resilience against slow hydrolysis, even when humidity sneaks up during rainy seasons—a practical advantage for anyone managing both bulk drums and small lots.

    Disposal and environmental handling also play a part in assessing its fit for purpose. 1-Chloro-2,2-Dimethylpropane breaks down gradually in natural systems, but its volatility demands prompt containment to avoid losses. Workers in blending and filling appreciate its faint aromatic character, which signals a leak well before concentrations rise toward regulatory thresholds.

    Material Handling and Worker Safety: Lessons Learned from Real Situations

    Anyone on a manufacturing floor knows safety means more than following a checklist. With 1-Chloro-2,2-Dimethylpropane, seal integrity counts—flanged gaskets or valve seats that tolerate this compound may suffer quicker than with straight-chain chlorides. We rotate stock based on FIFO principles and have replaced certain rubber seals more frequently since switching pumps that handled this product. Eye and skin protection goes without saying. A spill on the floor, left for long, tends to spread odor and causes slippery patches that regular degreasers struggle to clean without additional rinsing, so we swapped in a steam mop system that keeps floors safer.

    Bulk transfers call for grounded containers and real-time monitoring. One training session, a new operator overfilled a receiver; the resulting vapor cloud showed us that vigilance works best paired with practice and equipment upgrades. The compound’s moderate vapor pressure rules out open-air transfer, leading us to invest in closed-loop systems that both recover vapor and minimize occupational exposure. Workers quickly learned that odor is the first sign—far ahead of irritation—to pause and check valves or hoses. These small but vital details make a difference in a facility where similar-sounding compounds could lull even seasoned staff into complacency.

    Storage, Shelf Life, and Micro-Supply Adjustments

    As output scaled up, storage strategy evolved from basic drums to stainless or lined tanks. The storage life of 1-Chloro-2,2-Dimethylpropane depends on headspace atmosphere as well as ambient temperature. Our records show fewer complaints and rejected lots after we started purging tanks with nitrogen before sealing. Smaller users sometimes run into crystallization or layer separation if storage rooms run too cold, so telling customers the experience we gained about ambient control saved them from disruption. It seems basic, but verifying tight drum closures and checking desiccant packs prevents more product loss than recalibrating an analyzer ever did.

    On the micro-supply front, repeat requests from labs—both internal and external—for small-scale, high-purity lots led us to set up a dedicated line for bottling under inert gas. Cross-contamination with other alkyl halides cropped up once when staff reused cleaned but untested filling nozzles. Now, we swab and check before every small batch—this accounted for a measurable drop in out-of-spec returns.

    Transportation matters too. We saw less deterioration in product quality during long hauls after switching logistics partners who use isothermal trucks, especially in summer. Rapid turnovers, plus rotation based on production date rather than order size, keep all shipments fresher for users and minimize headaches.

    Applications from Factory-Based Observations

    Chemists in specialty synthesis call on 1-Chloro-2,2-Dimethylpropane where a branched C5 skeleton isn’t just decorative—it’s required for target molecule geometry. Some lubricants, surfactants, and plasticizers turn out with improved flow properties because this backbone disrupts crystallinity. Customer feedback guided us in fine-tuning process conditions when they struggled to overcome side reactions with linear analogues.

    Our process engineers have noticed that reaction setups using this compound often run cleaner, with less need for post-synthesis washes, due to the reduced byproduct profile compared to less sterically hindered chlorides. This, in turn, saves water and lowers effluent volumes—factoring into both cost and compliance for customers aiming for greener processes.

    Manufacturers of intermediates and functionalized molecules depend on predictable chain branching. Selectivity in alkylation reactions changes just enough with this specific isomer to tip process economics in favor of using our product—something pure data tables don’t always show. Synthetic novelties in crop science have emerged, and some new surfactant families started as pilot trials on just a kilo of our 1-Chloro-2,2-Dimethylpropane.

    We saw steady demand for purification, even among regular users. Some firms ran side-by-side syntheses and documented lower overall waste and solvent use with our batches versus cheaper, generic lots sourced abroad. Their feedback led us to focus on minimizing residual color bodies and trace oxygenates in each run, rather than just hitting headline purity numbers.

    Improvements Rooted in User Experience

    Adjustments on the factory floor often come from conversations with return customers. One customer building medical-grade polymers reported variable yields until we tightened impurity specifications based on shared results. Another noted that drum materials impacted product shelf life, prompting us to offer lined steel containers as an added option for long-term storage. Micro samplers installed in our shipping lab enabled faster order turnaround for research users and allowed them to test small batches before committing to full lots.

    By engaging directly with technical staff—rather than relying just on sales orders—we confirmed that solvent compatibility in their applications benefited from our efforts to push down trace polar impurities. A few custom blends of anti-static preservatives or lubricating additives emerged after we modified our cleaning regimen for filling lines. These tweaks often look minor from the outside but mean smoother runs and fewer production breakdowns for end users.

    In our ongoing efforts, plant managers mapped out places where old equipment introduced shed particles or trace metals. Upgrading specific reactor linings and tweaking filtration protocols helped reduce batch rejection rates and raised baseline purity, a change customers picked up on quickly. Working in partnership, not at arm’s length, delivers solutions that data sheets rarely anticipate.

    Regulatory and Environmental Outcomes: Straight Talk from Years of Compliance

    Compliance for any chlorinated hydrocarbon starts with record keeping and routine audits. In our own operations, we regularly update internal guidelines based on local and national regulations. Auditors care about not just paperwork, but whether operators know what’s in the lines and how to respond on the spot. Every batch receives detailed logging, and routine spot-checks test both product and containment systems for leaks and proper labeling. This practice grew out of one incident years ago where a mislabeled valve led to a misdirected transfer—an error caught quickly because our systems flagged inconsistencies.

    On the environmental front, our in-house air filtration and scrubbing setup cut vented emissions by over 80% compared to earlier methods. Not all regional facilities can claim the same, but we noticed across-the-board reductions in odor complaints and air monitoring results. Waste treatment partners handle spent solutions under strict agreements, and plant tours for environmental inspectors reinforce transparency at each processing stage. Feedback from nearby communities spurred us to publish routine environmental impact summaries—a move that, in retrospect, helped build better local relationships.

    Training new hires balances procedural teaching with scenario walk-throughs: what to do if a drum leaks, or a sample shows odd hues. Refresher sessions focus not only on theory, but on actual case studies from our plant history—the mistakes, their fixes, and how lessons learned change real practice on the next shift. These hard-earned insights shape a culture that values vigilance and builds trust both inside the fence and out in the marketplace.

    Future Directions: Learned Adaptability in Chemical Process Industries

    Markets for 1-Chloro-2,2-Dimethylpropane ebb and flow with trends in specialty chemicals, but core requirements remain steady: high purity, consistent outcome, thoughtful communication. Plant automation brought efficiency, but human operators still catch early signs of process shifts before machines flag them. In the last few years, requests for audit trails and traceability have increased, echoing food and pharma sector trends. We adjusted batch tracking so users can trace each batch back through every step, every test, and, when required, every staff hand who signed off on a checkpoint.

    Expanded collaboration with academic partners gives us better insight into how new generations of chemical engineers and synthetic chemists encounter the product. User workshops revealed demand for not only standard lots, but pre-packed samples under inert conditions or tailored impurity profiles. We built extra flexibility into scheduling for quick pivots to meet these changing expectations, which improved relationships and often sparked new application ideas that traditional feedback forms miss.

    On the global trade side, we’ve seen recent disruptions prompt customers to look locally for supply assurance. Our local presence, supported by a reliable upstream supply of raw materials, means less risk of shipment delays and more room to troubleshoot in real time. It’s also driven us to rethink logistics, storage, and contingency plans so both large customers and small labs have uninterrupted access.

    Continuous Product and Process Evolution

    The narrative surrounding 1-Chloro-2,2-Dimethylpropane is more than its place in catalogs or technical bulletins. Years refining our own process—from early steps of detection and control to nuanced changes in drum-filling and documentation—show that substance properties and reliability come from learning on the ground. We continue to invest in plant upgrades, spur staff training with real-world scenarios, and invite in constructive criticism from those who use the product every week.

    Knowledge accumulates batch by batch, problem by problem, shipment by shipment. The most useful advancement rarely lands from theory alone—it grows from how our staff, and our customers, actually work with the compound. This hands-on experience underpins each new improvement. Our approach lies not in rote checklists or abstract assurances, but in applied understanding, sustained by direct feedback and lived practice.

    Reliable results, delivery punctuality, and responsive adaptation aren’t marketing claims for us—they’re habits, developed through decades of chemical manufacturing for companies who know the difference between reading a spec sheet and running a process. 1-Chloro-2,2-Dimethylpropane, shaped by our combined expertise, becomes more than a name—it’s a well-earned outcome shared by everyone involved, from first shift to last mile.