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1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane

    • Product Name 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane
    • Alias Halon 1211
    • Einecs 221-229-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    692567

    Cas Number 2837-92-3
    Molecular Formula C2ClBr2F3
    Molecular Weight 297.28 g/mol
    Iupac Name 1-chloro-1,1-dibromo-2,2,2-trifluoroethane
    Appearance Colorless liquid
    Boiling Point 65-67 °C
    Density 2.165 g/cm3 (at 25 °C)
    Melting Point -35 °C (approximate)
    Refractive Index 1.426 (at 20 °C)
    Vapor Pressure 210 mmHg (at 20 °C)
    Solubility In Water Insoluble
    Smiles C(C(F)(F)F)(Cl)(Br)Br

    As an accredited 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 250 mL, with a red hazard label displaying chemical name, CAS number, safety pictograms, and secure screw cap.
    Shipping 1-Chloro-1,1-dibromo-2,2,2-trifluoroethane should be shipped in tightly sealed, corrosion-resistant containers under cool, dry conditions. It is classified as a hazardous material and must be transported according to relevant regulations, including labeling as a toxic and environmentally hazardous substance. Avoid exposure to heat, open flames, or direct sunlight during shipping.
    Storage 1-Chloro-1,1-dibromo-2,2,2-trifluoroethane should be stored in tightly closed containers in a cool, dry, and well-ventilated area away from heat sources, sparks, and open flames. Keep it away from incompatible materials such as strong oxidizers and alkali metals. Protect from moisture. Properly label containers and ensure appropriate spill containment measures are in place. Use only with adequate ventilation.
    Application of 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane

    Applications of 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane in Industrial Manufacturing

    As a specialized manufacturer of 1-Chloro-1,1-Dibromo-2,2,2-trifluoroethane, we supply this compound to a range of regulated sectors requiring selective halogenated intermediates. The following application scenarios detail its usage, compliance aspects, processing stages, and end products for each real-world industrial field.

    1. Pharmaceutical Intermediate for API Synthesis

    Major pharmaceutical manufacturers rely on 1-Chloro-1,1-Dibromo-2,2,2-trifluoroethane as a building block during multi-step synthesis of select active pharmaceutical ingredients (APIs), especially those requiring controlled fluorination and stepwise halogen exchange. During the key intermediate coupling process, process chemists introduce the material for halogenation reactions under strictly controlled batch protocols. Precursor management requires monitoring to meet residual solvent and impurity thresholds, with subsequent purification steps tuned to maintain target yields. The integration involves exact metering and continuous analytical support to ensure process reproducibility and regulatory acceptance of the resulting APIs.

    Industry compliance standards

    • Good Manufacturing Practice (GMP, ICH Q7)
    • Active Substance Master File (ASMF) guidelines (EMA/CHMP/QWP/558185/2010 Rev 3)
    • 21 CFR Part 211 (FDA)
    • Relevant country-specific pharmacopoeias (USP, EP, JP) for API precursors

    Typical usage ratio

    • Applied in a 0.1 to 0.5 molar equivalent relative to the starting substrate, adjusted according to reaction route and batch scale; excess can be minimized based on the degree of halogenation required

    Downstream process integration

    • Charged directly into synthesis reactors during intermediate halogenation step; addition timing and sequence critical to achieve target substitution;
    • Spent chemical managed by solvent extraction or distillation after reaction completion
    • Final isolation by preparative purification or crystallization prior to subsequent synthesis steps

    Final product types

    • Fluorinated and halogenated pharmaceutical intermediates
    • APIs for anti-infective and respiratory agents
    • Niche oncology drug precursors

    2. Agrochemical Synthesis for Selective Herbicides

    Industrial agrochemical plants apply 1-Chloro-1,1-Dibromo-2,2,2-trifluoroethane as a halogen donor in multi-stage herbicide active synthesis where precise fluorination and stepwise debromination are required for active molecule construction. Process engineers oversee reaction kinetics tightly, introducing the material by controlled dropwise addition to maintain selectivity and minimize unwanted side-reactions. The finished product purity is governed by stringent QC protocols and downstream removal of reaction by-products aligned with local and international agrichems compliance.

    Industry compliance standards

    • ISO 9001:2015 for quality assurance
    • Active Substance Registration under EU Regulation (EC) No 1107/2009
    • US EPA Pesticide Registration (40 CFR Parts 150–189)
    • Globally Harmonized System (GHS) for labeling and SDS requirements

    Typical usage ratio

    • 0.05 to 0.2 weight fraction in synthesis, tuned by required halogen substitution level and crop protection molecule design

    Downstream process integration

    • Introduced as a reagent for halogen exchange in reactor vessels during core molecule assembly
    • Used during batch or semi-batch operations depending on the complexity of the agrochemical pathway
    • Residuals neutralized in the work-up step before the isolation of actives

    Final product types

    • Selective fluorinated herbicides
    • Pre-emergent weed control actives
    • Halogenated pesticide intermediates

    3. Specialty Polymer Modification in Fluorinated Elastomers

    Manufacturers in the fluoropolymer industry utilize 1-Chloro-1,1-Dibromo-2,2,2-trifluoroethane in specialized polymer chain extension and end-group functionalization. Its halogen content allows precise tailoring of chain terminations, introducing unique chemical resistance or modifying solubility profiles within finished elastomeric materials. The chemical is introduced at controlled temperature and pressure within pre-polymer formulation, monitored under real-time spectroscopic control. This ensures accurate incorporation without undesired cross-linking, optimizing downstream fabrication for demanding sealing and lining applications.

    Industry compliance standards

    • ISO 9001:2015 for general manufacturing
    • ASTM D1418 for elastomer classification
    • UL 94 for polymer flammability
    • FDA 21 CFR 177.2600 for indirect food contact (where required)

    Typical usage ratio

    • Used at 0.5–2.0 phr (parts per hundred rubber) depending on required functional end-group concentration

    Downstream process integration

    • Charged during late-stage or post-polymerization modification steps
    • In-line blending with pre-polymers or direct addition to polymer matrix
    • Strict control of residence time and reaction temperature during chain termination

    Final product types

    • Fluoroelastomer O-rings
    • Chemical resistant gaskets
    • Specialty industrial seals

    4. Electronic Grade Cleaning Agent Formulation

    Leading electronics and semiconductor manufacturers adopt this raw material in blends for high-purity circuit board and microelectronic cleaning fluids. Its balanced halogen structure provides efficient solvency for organic residues while controlling volatility, reducing the risk of static buildup and contamination. Blending requires closed-system formulation to prevent atmospheric loss and to comply with occupational health and environmental management. The resulting cleaning solutions undergo low-residue evaporation and require strict moisture and ionic trace control to meet submicron device production standards.

    Industry compliance standards

    • IPC-5704 Cleanliness of Unpopulated PWBs
    • IEC 61340-5-1 for electrostatic discharge (ESD) protection
    • RoHS Directive 2011/65/EU and amendments
    • OEM-specific semiconductor cleanliness specifications

    Typical usage ratio

    • Introduced as 5–20% by volume in proprietary solvent blends, adjusted based on cleaning efficacy, substrate compatibility, and regulatory constraints

    Downstream process integration

    • Formulated into electronic cleaning baths or vapor-phase systems
    • Used for immersion or spray application stages of PCB manufacturing
    • Closed-loop recovery and filtration for waste minimization

    Final product types

    • Microelectronic and semiconductor cleaning fluids
    • Post-etch circuit board rinses
    • Printed circuit board cleaner concentrates

    5. Fluorinated Solvent Carrier for Analytical Reagents

    Producers of specialty analytical reagents select this compound as a high-performance carrier solvent for sensitive fluorine-based reagents. Its chemical inertness and halogen balance minimize interference with detection processes, while providing sufficient volatility for complete removal after method application. The dosing process demands precision to maintain analyte stability, with solvent blending and bottling conducted under inert atmosphere to ensure analytical grade purity throughout the supply chain.

    Industry compliance standards

    • ISO 17025:2017 laboratory management for traceability
    • REACH Regulation (EC) 1907/2006 for safe solvent supply
    • GLP (Good Laboratory Practice)
    • Specialty test kit and analytical reagent standards per ASTM E685/E1026

    Typical usage ratio

    • Used as the primary solvent or as 15–50% carrier phase in specialty reagent blends, tailored by analyte solubility and method sensitivity

    Downstream process integration

    • Employed during formulation/blending in cleanroom-controlled tank systems
    • Injected into individual vials prior to analytical test kit assembly
    • Bottled under nitrogen to prevent water uptake and reactivity

    Final product types

    • Analytical calibration standards
    • High-purity laboratory solvents
    • Certified reference materials for environmental and pharmaceutical testing
    Free Quote

    Competitive 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane: Crafting Quality at the Source

    At our facility, each batch of 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane takes shape not just through a formula, but through years of tangible production and scrutiny. This isn’t leverage, distribution, or speculation; this is actual chemical manufacturing. Handling 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane means more than reading its weight or purity—our staff interacts with the substance at every junction, testing, observing, and recording how every tweak in conditions during synthesis changes its profile.

    Specifications Built from Hands-On Experience

    The molecule itself, frequently called HCFC-1233Db or by its CAS number, stands apart for its pattern of halogenation—chlorine, bromine, and trifluoromethyl groups fixed on an ethane backbone. We observe both its physical clarity and its chemical stability batch by batch. Manufacturing this product requires strict attention to reacting gases and maintaining moisture thresholds, since stray water can degrade the yield and introduce problematic by-products. While routine specifications matter—such as precise molecular weight, measured boiling point, and purity level—these are not numbers plucked from an abstract. Our chemists run comparative purity checks using gas chromatography, and trace halide content isn’t a footnote. Overlooking these elements introduces variables that downstream users feel quickly, especially in applications where trace impurities cause side reactions, discoloration, or equipment fouling.

    We manufacture to serve producers of advanced polymers and specialty refrigerants. The product’s clean profile gives it a role where substitution with commercially similar, but less rigorously produced, materials often means lower yields or more complex waste disposal.

    Manufacturing Considerations You Won’t See from a Middleman

    Our team manages the real variables difficult to capture on a spreadsheet: precise pressure, feedstock timing, solvent grade, even the quality of the cooling water in jacketed reactors. If these drift, so does the end product. Each of these components, while trivial to someone focused on negotiation rather than process, means direct cost, risk, and stability to us. The challenges of handling the intermediates—the strong halogen gases, reactive intermediates, and corrosive by-products—are not theoretical; each step exposes our technicians to safety protocols and hard-won lessons from near-misses and unexpected maintenance issues. The stress on production equipment by halogenated compounds often doubles the typical maintenance cycle; we only learned which gasket compositions survive after years of trial, error, and field replacement.

    1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane leaves our tanks with an actual certificate tracing its journey, not just a reprinted supplier document. We maintain records tied to specific vessel entries, vacuum times, and reaction temperatures, reviewed and signed by the operators who ran the process.

    Real-World Product Performance

    In fluorinated chemistry, molecular differences determine everything from boiling point to market acceptance. A single halogen placement distinguishes legitimate solutions from non-performers in advanced manufacturing. Industrial users approach us seeking a product that performs reliably in specific syntheses—reactivity, solubility, and a margin of safety under thermal or catalytic stress that lower-grade substitutes rarely meet. The consistent feedback we hear after a first trial speaks to the difference between mass-sourced material and batches tracked and verified at every stage. Purity isn’t an arbitrary standard; it’s the line between a successful run and a hazardous shutdown.

    In our plant, impurities are not invisible, and variability is not inevitable. Operators run live spot checks as drums and intermediate tanks fill, pulling samples for thermal stability tests and measuring halide residues. If a tank’s temperature profile does not match the upper control chart boundary, production halts. Our scale-up and quality control mean far more than meeting a generic requirement.

    Uses Driven by Process Demands, Not Brochures

    We see the chemicals we make taken into solvent engineering, refrigerant blending, and polymer modification—all built on the molecule’s high density, halide reactivity, and fluorinated chain length. The market’s appetite for ever-lower emissions and stricter stewardship standards favors molecules with high chemical stability but short atmospheric lifetime. With those priorities, performance and compliance cut down to the composition of the actual molecules present in every delivery.

    1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane lands in environmental testing laboratories, research into refrigerant blends with lower ozone depletion potential, and polymer synthesis that leverages its unique pattern of halogenation to produce stable, high-performance materials. Our clients don’t buy this compound just for a name or a generic datasheet profile—they require a profile that maintains clarity, resists decomposition, and avoids leaving corrosive contaminants in expensive production hardware.

    Distinctions from Similar Halogenated Compounds

    Many halogenated ethanes share chemical logic: one or more carbons ringed by a mix of chlorine, fluorine, and bromine. The exact pattern—where each atom sits—makes a dramatic difference to both chemical behavior and industrial safety. In the case of 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane, the asymmetric distribution produces a boiling point and chemical reactivity distinct from the more commonplace difluorinated or monobrominated species. Those technical nuances aren’t trivia; they determine compatibility with catalysts and downstream reagents. If a client accepts a substitute—whether 1,1,2-tribromo-1,2,2-trifluoroethane or a simple trichlorofluoroethane—the reaction profile and phase handling diverge in practice.

    In the field, cost pressures sometimes push less scrupulous actors to rebottle or relabel close analogues. We address those risks directly by controlling our reactors’ charge materials at every stage and running IR and NMR confirmation on outgoing batches. A few dozen parts per million of an unwanted isomer is enough to foul downstream processes. Only manufacturers—including our own site—see those analytical traces at every lot level.

    Challenges Unique to Actual Production

    Maintaining quality for this compound involves issues that suppliers and brokers rarely discuss: coproduced halogenated by-products, polymer decomposition at high temperature, or off-spec reaction due to ambient humidity. On the manufacturing floor, the margin for error narrows each year as customers ask for higher purity, lower moisture, and reduced corrosive residue. Meeting these challenges requires ongoing investment in vessel linings, raw material specification, and environmental controls. Every maintenance cycle adds to our team’s hands-on knowledge. Polymer-lined gaskets, for instance, that look interchangeable on paper can mean unplanned shutdowns if a minor trace leaching occurs from a poorly chosen substitute. We learned these lessons under pressing timelines, not by reading a circular or market brochure.

    One of our recent continuous improvement runs drove us to revisit the condensation train after data showed a measurable increase in halide vapor escape during summer months. Instrument readings and equipment service records told the story—a slightly higher ambient humidity led to changes in product capture rates and demanded recalibrated drying periods. That level of detail emerges from real-world operations, not theoretical optimization.

    Supporting Facts from the Production Line

    Data collection remains a core aspect of everything we do—with product releases depending on real-time measurements, not retrospective guesswork. Automated logging tracks pressure, feed rate, distillation profile, and critical endpoint temperatures. Each batch receives a unique identifier handwritten at the site, correlating to the raw material lot and reactor vessel number.

    The learning curve on synthesizing 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane brings lessons that translate directly into reliability for the user. Our R&D team tracks not only end product but waste flows, reaction off-gases, and even micro-contamination risks in cooling media. These findings feed directly into adjustments that keep us aligned with both regulatory and industry best practices. Years of direct production translate into decisions that favor robust yields, overt waste capture, and minimized risk—from the dynamic seals on pumps to the continuous pH monitoring in waste neutralization tanks.

    Solutions and Continuous Improvement

    We do not wait for market feedback to address issues. Much of our process improvement comes from weekly review meetings, where production and technical staff compare batch data and field application notes. On one occasion, small but consistent color drift identified during downstream polymerization led back to a specific lot of solvent used during our own halide distillation. Replacing a single supplier and doubling vacuum hold duration restored clarity to the end product—an improvement that persisted across several months and translated into fewer downstream complaints.

    Waste management and environmental protection have always required direct involvement; no protocol stays on the shelf. Vented halogen gases are scrubbed and neutralized, with capture rates audited for continuous reduction in fugitive releases. Disposal contracts tie back to our regimen of in-house waste separation to eliminate accidental contamination of outgoing nonhazardous waste. Each improvement builds on actual experience—not theoretical possibilities that may never materialize in a sales-driven pipeline.

    Importance of Controlled Production at the Source

    Without direct accountability for every step of the process, subtle shifts quickly balloon into problematic batches. Third parties lose sight of these links since they encounter product in bulk, not as a process evolving minute by minute on a chemical line. We see the momentary cloudiness in a sight glass, the unexpected sound of a cavitating pump, the telltale electrical draw on a heat exchanger. Our staff reacts to these events, taking action grounded in the kind of knowledge that comes only from repeated experience under pressure.

    The current landscape, where regulatory requirements tie directly to traceability and environmental impact, does not reward shortcuts. We hold ourselves to standards that anticipate regulatory shifts—logging, retention, and transparency that hold up under review. Partnerships built with users of our 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane reflect this mindset, because when something goes wrong it’s our production that gets scrutinized—not the paperwork of an intermediary.

    Listening to Industry and Responding with Real Solutions

    We keep in regular contact with industrial clients to gather application data, not just to tick boxes on annual reviews. The insights that matter come from open exchanges: last year a processing partner reported sporadic fouling in heat exchangers due to unanticipated polymer build-up. We checked the batch data, identified a trace-bromide variance, and adjusted both our reaction endpoint and solids filtration depth. Successful chemical commerce, from our perspective, comes from solving these issues at the source. Our guarantee stems from the fact we can stand behind each drum with process details and technical staff ready to answer for each parameter.

    It’s easy to treat 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane as an interchangeable commodity. Yet at our site each incremental improvement arises from hands-on vigilance. The smallest insight—from the calibration curves logged via our chromatography runs, to the recalibration of a reflux condenser after an unusual seasonal spike in water temperature—plays a part in material that arrives at your plant ready for immediate use.

    Meeting Today’s Demands—Tomorrow’s Challenges

    We manufacture more than a chemical; we deliver a consistent, trusted input for advanced industry. Handling complex molecular profiles, highly halogenated feeds, and stringent customer demands takes more than written instructions. Over years, our approach has evolved—refining reaction monitoring protocols, automating transfer steps, and building operator expertise through repetition and post-run debriefs. This process transforms theoretical procedures into practiced skill; each operator draws on their own catalogue of experience, improving outcomes batch by batch.

    Increasing interest in sustainable chemistry and low-emission alternatives puts pressure on every part of our process. Whether for new refrigerant research, greener polymer blends, or experimental solvent systems, users of 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane demand not only product, but proof—auditable confidence born of real manufacturing. We are not insulated from the fresh challenges imposed by regulation or customer innovation. Instead, we measure our success in reduced waste, higher purity, and a declining error rate that comes only from persistent attention at every step.

    Differentiation Based on Experience, Not Just Molecular Structure

    What sets our 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane apart is the documentary evidence backstopping every batch—the familiarity that comes from production line setbacks, troubleshooting, and breakthrough. The industry is crowded with suppliers who measure their value in inventory and quick quotations. Our contribution is practical reliability anchored in direct technical skill under pressure.

    Every tank, every drum reflects the knowledge of operators who see actual conditions: the look of a proper distillation head cut, the sound of a vacuum reaching full draw, the tactile sense of well-lubricated seals during a routine swap. These details vanish from the conversation when material arrives from a broker or off a repack line. We believe those signatures—recorded, reviewed, and continuously improved—create a product you can trust for demanding applications.

    Commitment from Our Production Floor to Your Application

    Nothing about 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane stays abstract from our vantage point. From lining up raw material trains before dawn, to recording the uptick in solution clarity after swapping a batch filter mid-production, our process remains rooted in informed practice. The world now asks for more than basic compliance: our clients, their customers, and the regulators expect a story behind every product—one grounded in facts, traceability, and hard-won results.

    We move chemicals because we shape, monitor, and safeguard every step. Each lot of 1-Chloro-1,1-Dibromo-2,2,2-Trifluoroethane we produce represents that commitment. Our shop floor sees real value in process control, environmental care, and a problem-solving mindset that treats every challenge as an opportunity for technical advance. This is what differentiates products built on experience from commodities circulated in markets.

    The compound leaves our gates not just as a molecule, but as the product of a tightly managed, transparently recorded, and thoroughly understood process—ready to meet your most demanding application and carry the full weight of everything we have learned along the way.