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1-Bromopyrene

    • Product Name 1-Bromopyrene
    • Alias 1-Bromopyren
    • Einecs 207-622-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    242696

    Cas Number 519-59-5
    Iupac Name 1-Bromopyrene
    Molecular Formula C16H9Br
    Molecular Weight 297.15 g/mol
    Appearance Yellow crystalline powder
    Melting Point 114-116 °C
    Boiling Point 428.2 °C at 760 mmHg
    Density 1.607 g/cm³
    Solubility In Water Insoluble
    Purity ≥98%
    Smiles C1=CC2=C3C(=CC=C2)C=CC4=CC=CC=C14Br
    Flash Point 217 °C
    Storage Conditions Store at room temperature, keep container tightly closed

    As an accredited 1-Bromopyrene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1-Bromopyrene is supplied in a 25-gram amber glass bottle, tightly sealed, with hazard labeling and chemical identification details printed.
    Shipping 1-Bromopyrene is classified as a hazardous material and must be shipped according to strict regulatory guidelines. It should be packaged in tightly sealed, chemically resistant containers and clearly labeled. Shipping must comply with international and local protocols (e.g., DOT, IATA), typically requiring transport via ground or air as a regulated substance.
    Storage Store 1-Bromopyrene in a cool, dry, well-ventilated area, away from direct sunlight and sources of ignition. Keep in tightly closed, clearly labeled containers made of compatible materials. Avoid exposure to oxidizing agents and strong acids. Use secondary containment to prevent spills. Ensure storage location is equipped with appropriate safety equipment, such as spill kits and eyewash stations.
    Application of 1-Bromopyrene

    Applications of 1-Bromopyrene in Industrial Manufacturing

    As a direct manufacturer specializing in polycyclic aromatic hydrocarbons, we supply 1-Bromopyrene as a high-purity intermediate to support advanced downstream production. The following application scenarios detail how our product integrates into established industrial processes, focusing on real market demand and regulatory standards.

    1. Advanced Organic Semiconductor Material Synthesis

    1-Bromopyrene serves as a functional intermediate in the production of high-performance organic semiconductors. Process engineers introduce this material primarily during Suzuki or Stille cross-coupling reactions to construct complex aromatic frameworks. Its use enables the targeted production of specialized pyrene derivatives for use in high-mobility thin-film transistors and organic light-emitting diodes (OLEDs). This application requires careful control of reaction conditions and strict purity management, in line with global electronics quality protocols.

    Industry compliance standards

    • RoHS Directive (EU 2011/65/EU)
    • REACH Regulation (EC 1907/2006)
    • IEC 61249-2-21 Halogen-free requirements
    • ISO 9001 Quality Management Systems

    Typical usage ratio

    • Mol fraction: 1-1.5 eq relative to aryl boronic acid, adjusted by final polymer chain length requirements
    • Batch scale: 3-15% by weight, depending on device architecture

    Downstream process integration

    • Added at the coupling step after monomer preparation
    • Purified by chromatographic or recrystallization techniques
    • Transferred to polymerization or device fabrication units
    • Monitored by HPLC and GC-MS for trace halogen content

    Final product types

    • Organic field-effect transistors (OFETs)
    • OLED display backplanes
    • Photodetector active layers
    • Electroluminescent coatings

    2. Fluorescent Probe and Dye Manufacturing

    Manufacturers use 1-Bromopyrene as a building block for synthesizing fluorescent dyes employed in biochemical research and analytical chemistry. The compound's extended conjugated structure, when modified through further functionalization, delivers high quantum yield and specificity in fluorescence labeling applications. Tight control of synthetic routes and batch consistency ensures compliance with laboratory reagent standards and enables downstream conjugation to biomolecules.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals
    • ISO/IEC 17025 Laboratory Accreditation
    • IUPAC Nomenclature Conventions
    • ISO 19001 Reagent Quality Standards

    Typical usage ratio

    • 10-25% molar ratio as core scaffold for pyrene fluorescent dyes
    • Concentration tuned by emission wavelength and solubility profile

    Downstream process integration

    • Introduced in the halogenation or coupling stage of dye synthesis
    • Reacted with amino or carboxyl-functional reagents for derivative formation
    • Subjected to chromatographic purification and crystallization
    • QC by fluorescence spectrophotometry and mass spectrometry

    Final product types

    • Pyrene-based fluorescent labels
    • DNA/RNA staining dyes
    • Immunofluorescence probes
    • Quantitative analysis kits

    3. Synthesis of Polycyclic Pharmaceutical Intermediates

    Chemical process operators employ 1-Bromopyrene as a selective halogenated aromatic precursor in the preparation of advanced pharmaceutical intermediates. Its brominated position allows for regioselective metal-catalyzed coupling, enabling access to functionalized polycyclic scaffolds used in drug discovery pipelines. Material traceability, impurity profiles, and process validation are core requirements throughout synthesis to comply with pharmaceutical standards.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP <823> for Synthesis of Radiopharmaceuticals
    • Ph. Eur. Monographs for Intermediates
    • ISO 22716 for Good Manufacturing Practices

    Typical usage ratio

    • Stoichiometric ratio: 1:1 with organometallic catalysts or ligands
    • Percentage integrated based on target intermediate’s synthetic route (commonly 8-20%)

    Downstream process integration

    • Charged into catalyst-assisted coupling reactors following solvent adjustment
    • Undergoes continuous extraction and phase separation
    • Intermediate transferred to final API synthesis or advanced transformation steps
    • Controlled documentation for batch traceability and impurity monitoring

    Final product types

    • Polycyclic APIs and research intermediates
    • Analytical reference substances
    • Candidate molecules in oncology and CNS drug classes
    • Custom synthesis building blocks

    4. Environmental Analytical Reference Standard Production

    Producers of environmental standards and analytical calibration materials utilize 1-Bromopyrene as a precise reference compound for polycyclic aromatic hydrocarbon (PAH) quantitation in environmental monitoring. Scientists require accurately characterized and certified materials to ensure regulatory compliance in air, water, and soil PAH testing. Every batch must meet strict metrological traceability, accompanied by comprehensive certificates of analysis.

    Industry compliance standards

    • ISO 17034 for Reference Material Producers
    • USEPA Method 610 and Method 8270D
    • EN 16687 Indoor Air Quality Assessment Standards
    • OECD GLP Regulations

    Typical usage ratio

    • Standard solutions: 10-1000 μg/mL, depending on instrument calibration requirements
    • Solid-state reference standards as 0.1-5% blends with inert carrier matrices

    Downstream process integration

    • Dissolved in high-purity solvents for gravimetric standard preparation
    • QC by GC-MS or HPLC against certified reference spectra
    • Packaged under anhydrous, light-protected conditions to prevent degradation
    • Shipping compliance with hazardous material transport protocols

    Final product types

    • Certified PAH reference solutions
    • Matrix-matched calibration kits
    • Analytical proficiency testing samples
    • Environmental laboratory control standards

    5. Specialty Polymer and Copolymer Chain Modification

    Polymer manufacturers introduce 1-Bromopyrene at specific steps in the synthesis of specialty copolymers to impart advanced optical and electrical properties. Through controlled polymerization methods such as atom transfer radical polymerization (ATRP) or step-growth mechanisms, bromopyrene units incorporate into the main chain or as pendant groups. This material enables fine-tuning of polymer photoactivity, enhancing application in niche optical fibers and advanced composite materials.

    Industry compliance standards

    • ISO 9001 for Quality Management in Polymers
    • ASTM E2877 for Polymer Structure Analysis
    • REACH (EC 1907/2006) for Registration and Safety
    • RoHS (EU Directive 2011/65/EU) for Electronic Materials

    Typical usage ratio

    • Loading: 0.25–5% by weight, tailored to target polymer property profile
    • Adjustment based on degree of polymerization and reactivity ratio

    Downstream process integration

    • Blended into monomer feedstock before initiation of polymerization
    • Monitored via NMR and GPC for precise chain integration
    • Polymers isolated by precipitation and re-extraction procedures
    • Tested for photophysical and electrical characteristics

    Final product types

    • Fluorescent high-performance polymers
    • Conductive composites for electronics
    • Optical fiber core and cladding materials
    • Photoresponsive coatings and adhesives
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    Competitive 1-Bromopyrene prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    1-Bromopyrene: A Perspective from the Manufacturer

    Unveiling Our Experience with 1-Bromopyrene

    In our manufacturing plant, 1-Bromopyrene occupies a unique place on both our production floor and our innovation agenda. Years of hands-on work with aromatic chemicals have made it clear—certain compounds continue to drive research and application progress in ways that often go underappreciated outside the lab. 1-Bromopyrene (C16H9Br, CAS 1714-29-0) is one of these molecules. Our teams produce this chemical with the purity and consistency that precise applications demand, keeping in mind the practical needs of researchers and technical users who rely on our output for results that matter.

    Understanding the Properties That Matter in Practice

    From the vantage point of our own reactors and purification equipment, 1-Bromopyrene expresses itself as a pale crystalline solid, with a high degree of photostability and a melting point that allows straightforward handling and shipping, even under challenging conditions. Our QC team measures purity by HPLC, ensuring final batches above 98% unless special grades are requested. We’ve found that moisture control during handling and packing makes a real difference, minimizing the chance of trace hydrolysis or bromine release, which can otherwise complicate downstream applications.

    Every specification we offer for 1-Bromopyrene—particle size for crystalline grade, residual solvents, bromine content—is built from repeated feedback loops with our long-term customers, particularly in advanced material synthesis. Not every lab or commercial user requires ultra-high purity, but consistency in melting point, appearance, and spectroscopic fingerprint saves time and reduces surprises in scale-up or pilot production. Actual end users tell us that having a reliable, single-source manufacturer for this compound produces more tangible value than incremental improvements in technical data sheets.

    Where 1-Bromopyrene Finds Its Relevance

    We first began synthesizing this compound to serve university researchers focusing on organic semiconductors. Since then, its application range has only widened. 1-Bromopyrene stands out in the creation of polycyclic aromatic hydrocarbon (PAH) derivatives, especially when selectivity matters. Scientists use it as a precursor for functionalized pyrene systems—derivatives that will carry new side chains, linkers, or electron-withdrawing groups. Our product serves as the brominated building block in Suzuki and Stille coupling reactions, which remain foundational in the synthesis of novel organic materials.

    Whether the work is aimed at OLED research, organic field-effect transistors, or sensing devices, 1-Bromopyrene consistently appears as a go-to intermediate. Our customer interactions often reveal subtle differences in solvent choices, reaction times, and catalyst loads, but one constant is the need for predictable reactivity at the 1-position—the very reason we monitor regioisomeric purity so closely in our batches. In every kilogram, we work to minimize other positional isomers, because even a few percent contamination introduces significant variability into downstream reactions.

    Beyond Electronics: Expanding Applications in Life Science and Analysis

    It’s not only materials scientists who knock on our door. Over the past decade, biochemists and environmental chemists have used 1-Bromopyrene and its derivatives to trace metabolic pathways, probe environmental contamination, and serve as model pollutants. 1-Bromopyrene allows for the introduction of radioisotopic or fluorescent tags, making it invaluable in mechanistic studies. In this context, we keep our analytical reporting robust, so that even trace contaminants—whether from starting materials or process aids—remain transparent to researchers conducting high-stakes experiments.

    We also supply batches where ultra-low levels of metals and halides matter, especially for analytical laboratories benchmarking trace detection equipment. Here, our manufacturing discipline—meticulous distillation, shielding from air and light during final steps, and careful packaging in amber glass—translates directly into the confidence our customers can place in their reference materials.

    Distinguishing 1-Bromopyrene from Similar Compounds

    Someone new to advanced aromatics might ask, why not just use unsubstituted pyrene, or pick a different halogenated derivative? Our experience shows that the positional selectivity of the bromine atom in 1-Bromopyrene matters above all. The reactivity of the 1-position enables specific transformations in cross-coupling chemistry. Chlorinated or fluorinated analogs react differently—slower, less predictably, or with different product distributions. Iodinated pyrenes can provide heightened reactivity but often introduce more cost and preparation complexity, both in our factory and in customer labs.

    The physical properties also vary across the pyrene series. 1-Bromopyrene offers just the right balance of melting point, crystallinity, and solubility for routine purification, handling, and storage. Our customers working in large-scale reactions frequently emphasize that stability and minimized volatility make this compound easier to store and ship than its lighter halogenated cousins. Each batch is packed with this feedback in mind, using moisture and light barriers to maintain its analytical and practical value.

    Why the Manufacturing Source Makes a Difference

    Some buyers source chemicals from relatively anonymous supply chains, where the only information provided is a specification and a promise of availability. That’s rarely enough for sophisticated research and manufacturing programs. Because we control the entire synthesis and purification process, we can account for batch-to-batch variations, identify and eliminate sources of extraneous halides or aromatic byproducts, and tweak our upstream steps in response to market and regulatory changes.

    We’ve witnessed situations where customers encountered unexpected results due to low-grade or improperly stored material from unvetted sources. Impurities below the reporting radar show up as background noise in high-sensitivity analysis, or, worse, lead to side reactions in a multi-step synthesis. By sourcing directly from us, end users cut down this risk considerably—and get a real person to discuss their process or troubleshoot together if questions arise.

    Quality Assurance Rooted in Direct Production

    Producing 1-Bromopyrene at commercial scale brings unique challenges. Pyrene’s batch-to-batch source variability, sensitivity in the bromination step, and the need for rapid purification all keep our technical staff vigilant. To keep up with demand, we have invested in closed reaction systems with both temperature and pressure control. Regular spent catalyst analysis, continuous monitoring of hydrogen bromide evolution, and fine-tuning of distillation steps allow us to achieve consistent yields and purity with each run.

    Several standards underpin our approach to quality, but perhaps the most important is the judgment exercised by seasoned chemists on our team. Analytical tools—GC, HPLC, NMR—are central, but hands and eyes play a role too. Crystal color, particle flow, and the readiness of final product to dissolve without residue set the tone for how we evaluate actual batches prior to shipment.

    Meeting the Needs of an Evolving Market

    Over time, requests for custom purification, special packaging, or tailored documentation have grown. Some research groups ask for certified absence of polycyclic contaminants due to analytical interference concerns. Others require large drum quantities where anti-static measures and moisture control become critical. We’ve developed protocols to fill these requests without delaying lead times, recognizing that modern R&D often runs on just-in-time delivery schedules.

    Several production partners running pilot plants in the advanced material or dye sector have particularly challenging requirements—batch traceability from raw material to final lot; detailed COAs; or direct consultation with our technical managers about downstream suitability. This two-way conversation keeps us aware of shifting regulatory expectations (including REACH, TSCA, and other compliant pathways), as well as technical bottlenecks in application fields such as smart textiles or nanocarbon fabrication.

    Adapting to Sustainability and Environmental Concerns

    Pyrene derivatives like 1-Bromopyrene often draw scrutiny for environmental persistence and toxicity. While not all research can switch to more benign alternatives, our facility addresses these issues head on—by strict effluent management, closed-loop solvent systems, and energy recovery from waste heat. Over the past three years, we’ve upgraded our containment and recovery systems to minimize environmental footprint, not simply out of compliance but because waste reduction translates directly into less risk and lower cost.

    We also support green chemistry initiatives among our clients through honest dialogue about potential alternatives, safer disposal, and improved recycling options for packaging and unused product. In-house, physicochemical data collected over years of operation inform our hazard communication and training programs for every employee who handles or ships 1-Bromopyrene. We see it as a point of pride to make these real-world lessons available to customers navigating ever-changing environmental and safety regulations.

    Building Knowledge Networks—Not Just Selling a Molecule

    Our future outlook for 1-Bromopyrene aligns with our continued presence in high-value, technically demanding markets. To support deeper knowledge sharing, we keep lines of communication open with project teams, R&D consortia, and regulatory experts. A recurring theme among our customer base is the need for clarity—clear information on potential use cases, process pitfalls, and even historical performance in established synthesis routes.

    If a batch reveals an unanticipated analytical impurity or an inconsistency in reactivity, we don’t see it as “good enough” until the root cause is found and communicated. That often means running additional validation, sharing spectra, or convening call-in sessions with lead chemists on both sides. The benefit for both ends is a more robust foundation for current and future applications, eliminating painful repetition of avoidable problems and allowing our clients to push innovation forward.

    The Future of 1-Bromopyrene in Science and Manufacturing

    From our manufacturing floor to analytical labs, 1-Bromopyrene continues to demonstrate its utility as more than a chemical intermediate. Many of today’s challenges in functional materials, analytical science, and even environmental research require building blocks with both predictable and tunable qualities. We observe that the line between academic research and commercial product development keeps blurring, with teams from both sectors reaching out with requests for application-specific improvements—ranging from enhanced purity grades to customized documentation supporting grant applications or IP filings.

    Our internal process has shifted accordingly, with shorter feedback loops, faster iterations on purification protocols, and commitment to keeping our analytical tools at the leading edge. The demand for 1-Bromopyrene in electronic device prototyping, for instance, shows no signs of slowing. Yet we see equally strong, if quieter, growth in environmental tracing, forensic analysis, and bioimaging fields.

    Final Thoughts from the Factory Floor

    Day after day, our manufacturing teams turn raw pyrene into a brominated product whose value reaches well beyond its chemical formula. Years in the field continually reinforce this lesson: reliability in chemicals like 1-Bromopyrene supports reliability all along the innovation chain. Through careful attention to process control, open communication with technical users, and a willingness to adapt as science moves forward, we stay committed to putting the best materials into researchers’ and manufacturers’ hands—helping our clients bring their own breakthroughs to life.