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HS Code |
898527 |
| Productname | 1-Bromodocosane |
| Casnumber | 661-19-8 |
| Molecularformula | C22H45Br |
| Molecularweight | 389.50 g/mol |
| Appearance | White solid |
| Meltingpoint | 58-62 °C |
| Boilingpoint | 410.2 °C at 760 mmHg |
| Density | 0.858 g/cm³ |
| Solubility | Insoluble in water |
| Smiles | BrCCCCCCCCCCCCCCCCCCCCCC |
As an accredited 1-Bromodocosane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 1-Bromodocosane is packaged in a 25-gram amber glass bottle with a secure screw cap and proper hazard labeling. |
| Shipping | 1-Bromodocosane is shipped in sealed, labeled containers compliant with chemical safety regulations. The packaging ensures protection from moisture and physical damage during transit. The substance is handled with care according to safety guidelines, and shipping documents include hazard classifications and handling instructions. Expedite shipping may be available upon request. |
| Storage | 1-Bromodocosane should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizing agents. Protect from moisture and direct sunlight. Ensure that the storage area is equipped to handle chemical spills and is clearly labeled to avoid accidental misuse or contamination. |
Applications of 1-Bromodocosane in Industrial Manufacturing1-Bromodocosane serves as a specialty intermediate in select chemical manufacturing sectors, supporting complex downstream synthesis and as a specialty additive in high-value industrial applications. We manufacture this chemical to meet strict purity and lot consistency, based on direct feedback from leading downstream producers. Below we detail real application segments with precise technical roles, regulatory context, integration points, and final product types. 1. Pharmaceutical Intermediate SynthesisIn pharmaceutical manufacturing, 1-Bromodocosane acts as a long-chain alkyl bromide intermediate for the synthesis of active pharmaceutical ingredients (APIs), such as lipophilic prodrugs or alkylated surfactant agents used in oral and topical formulations. Production lines incorporate the material during late-stage functional group modification of precursor molecules, specifically through nucleophilic substitution and alkylation processes. Formulators adjust input based on targeted chain length and substitution pattern, crucial for final API bioavailability and consistent batch reproducibility. All stages of raw material management, reaction monitoring, and impurity profiling follow current cGMP practices, with traceability from batch to shipment. Frequent end use cases involve the production of specialty APIs that require enhanced hydrophobicity or membrane permeability, often targeting oncology or neurology drugs where controlled solubility is pivotal. Industry compliance standards
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2. Cosmetic and Personal Care Additive SynthesisManufacturers in personal care and cosmetic sectors utilize 1-Bromodocosane to build specialty wax esters, long-chain alkylquaternary ammonium compounds, and silicone-compatible hydrophobes. The raw material enters the synthetic workflow where extended carbon chain structures impart unique tactile, emollient, or film-forming properties. Final cosmetic esters support high stability in emulsions and improve water resistance in decorative products. The additive aligns with ISO-compliant ingredient audits and downstream traceability protocols, suited for skin care and hair conditioning systems wherein strict impurity and residual solvent controls are set by EU and US regulation. QC labs confirm residue profiles through GC-MS to comply with IFRA safety recommendations when ingredients reach the skin contact or rinse-off product lines. Industry compliance standards
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3. High-Performance Lubricant Additive FormulationIn industrial lubrication, 1-Bromodocosane functions as a controlled-release alkyl donor and friction modifier precursor for formulating high-performance greases and specialty synthetic oils. Leading additive formulators blend it post-refining, targeting the creation of esters and customized surfactants with extended chain stability for automotive, aerospace, and precision machinery applications. Downstream blending follows ISO-certified batch documentation and temperature-controlled staging. Inspection focuses on the prevention of brominated byproduct carryover into the base oil, demanding precise dosing and validated chain termination reactions. This integration ensures compliance with OEM lubrication system standards in high-stress operational settings. Industry compliance standards
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4. Surfactant Manufacture for Industrial Cleaning1-Bromodocosane supports the targeted synthesis of specialty surfactants, including long-chain alkyl sulfates and quaternary ammonium compounds, required for producing industrial-strength cleaning formulations. Downstream chemical manufacturers incorporate the raw material during the alkylation or sulfation stages, capitalizing on the extended carbon chain to impart low-foam, high oil-solubilizing capacity in formulated detergents designed for manufacturing, transportation, and energy sector cleaning. Raw material management and process QA follow local and international chemical control standards, with full MSDS traceability and monitoring for residual bromide content. All resulting surfactants undergo value-added blending for applications that demand controlled volatility and chemical compatibility with metal, plastic, and composite surfaces. Industry compliance standards
Typical usage ratio
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Manufacturing 1-Bromodocosane each day brings years of practical insight to the table. On the production line, every batch teaches something new about this specialty brominated compound, and there’s a real satisfaction seeing how reliable processing methods result in a consistently high-quality product. The full chemical name, 1-bromodocosane, tells the story: a 22-carbon long-chain alkyl bromide, C22H45Br, with the bromine atom fixed on the very first carbon. This linear structure makes it a useful intermediate for a range of industries, especially where specialty surfactants or alkylating agents need predictable reactivity and a robust hydrocarbon backbone.
Producing 1-Bromodocosane starts with strict handling of raw docosane. Only material with well-controlled purity lands in the reactors, reducing unnecessary byproduct formation and headaches downstream. The bromination step needs careful temperature management—not just for safety, but to keep the bromine addition strictly at the alpha position, ensuring that every molecule carries its halogen on the end of the chain. Years of tweaking these parameters paid off in terms of yield and stability. The resulting product runs as a white, wax-like solid at room temperature, with a melting point reflecting the long alkyl tail: around 45–48°C, much higher than lighter brominated paraffins due to the extended chain and crystal packing.
Clients in specialty chemical and surfactant industries often ask for clear and consistent melting data. Out of the reactor, in-house purification tackles remaining unreacted hydrocarbons to push purity above 98%. Only hands-on knowledge of vacuum distillation and repeated crystallization rounds separate out colored byproducts. It’s easy to underestimate how much in-process human judgment goes into producing a reliable kilo or drum.
Plenty of our customers have experience with shorter-chain brominated n-alkanes—like 1-bromododecane or 1-bromooctadecane—and initially expect similar behavior from 1-Bromodocosane. In practice, that’s rarely the case. The increased chain length delivers fresh properties: higher melting and boiling points, reduced volatility, and a much more pronounced waxy feel. This means safer transportation and less material loss to evaporation—but it also requires a heated drum to pour or pump the product, especially in cooler climates or unheated storage.
Years spent troubleshooting customer processes taught us that using a long-chain bromide like 1-Bromodocosane can solve problems that shorter chains never address. For example, customers aiming for specialty cationic surfactant manufacture sometimes find that short-chain alkyl bromides react too aggressively, forming unwanted byproducts or tearing apart sensitive functional groups. The docosane backbone occupies more molecular space, moving reactivity to the right pace for controlled, step-wise synthesis. It creates a soft, surface-active end product with tailored solubility in oils and waxes—a property critical for modern emulsion and lubrication chemistry.
Large-scale bromination creates potentially reactive byproducts—dibromoalkanes, overoxidized fragments—that sap both efficiency and product shelf life. Practical experience drove us to install strict batch monitoring, using both classic distillation techniques and modern GC-MS for trace impurity profiling. Spotting parts-per-million chlorinated or iodinated contaminants gets easier with years of hands-on sampling. This isn’t just a box-ticking exercise; downstream customers see benefits in reproducible performance, fewer processing anomalies, and steady long-term product behavior. As regulations change, there’s no substitute for a documented, traceable production history.
Customers in the fragrance, fine chemical, and advanced lubricant market sectors rely on this consistency. One off-spec batch might not damage a blending line, but it risks downstream quality and regulatory headaches that can ripple for months. The focus always lands on performing the job right, every single time, not just because the specs demand it, but because it avoids trouble—both for our plant and for anyone formulating with our product.
In many labs, 1-Bromodocosane gets picked as a key building block for synthesizing quaternary ammonium compounds, tailored surfactant chains, or lubricant additives with high thermal stability. The standard grade fits most specialty requirements, but for projects facing higher regulatory scrutiny—pharma intermediates, personal care, or food-adjacent uses—the process shifts to even tighter purification steps. This covers in-process checks on residual solvents as well as careful documentation of possible heavy metal or halide ion traces.
Getting it right goes well beyond the original order. We invested in robust technical support because customers often face unexpected challenges when scaling from beaker to bulk. For example, the physical properties of 1-Bromodocosane make it ideal for slow-diffusing, tightly packed surfactant monolayers, but the same stickiness complicates blending with lighter oils. Upstream, the bromine atom brings reliable reactivity for alkylation or substitution, whether in making potential drug delivery agents or next-generation anti-static coatings. Knowing this, the technical team regularly runs bench-scale simulations of anticipated customer reactions. These tests highlight potential bottlenecks customers might hit and help smooth their transitions to production scale.
The heart of any specialty chemical is reliable sourcing and dependable chemistry. At plant scale, this demands dedicated equipment not just for bromination but for full decontamination cycles, minimizing risk of cross-contamination. Strong separation of process lines for 1-Bromodocosane and shorter-chain homologs means no co-mingling with C18 or lower alkyl bromides, preserving product identity. On site, careful bulk packaging, inert atmosphere sealing, and temperature-stabilized storage tanks keep the material dry and oxidation-free.
For industrial-grade material, performance hinges on more than lab data—it’s about real-world handling and reliability. Even the best analytical certificate won’t replace firsthand troubleshooting of caking along tank bottoms or figuring out how to reduce color drift during high-temperature transfers. Years of observations taught that even subtle tweaks in solvent ratios during recrystallization can yield a product that remains free-flowing and bright for months. These small wins matter and build lasting customer trust.
Manufacturing brominated compounds requires diligence and respect for safety. The bromination process operates at elevated temperatures, producing significant fumarate fumes if not tightly contained. Early in our process history, a learning curve around ventilation, scrubber selection, and personal protection drove plant redesign. Installing state-of-the-art halogen scavengers and upgrading containment now means that every batch leaves the facility with emission levels well below local and international thresholds. Operators benefit from intensive annual training, not just in compliance but in the real “why” behind procedures, reducing accidents and minimizing waste. As a consequence, neighboring communities see cleaner air and less risk of accidental exposures.
Typical downstream uses of 1-Bromodocosane often avoid hazardous environments. Still, we view rigorous documentation as essential in every drum shipped. Traceable records not only simplify customer audits—they encourage ongoing improvement in our own practices. In an age where environmental criteria guide buying decisions more and more, controlling both process safety and waste management always earns long-term business.
The specialty chemical market faces continual regulatory tightening—across brominated intermediates, new substance notification, and green chemistry goals. A decade ago, only large multinational customers checked for exact impurity breakdowns or carbon chain distributions. Now, even niche buyers expect batch-level certificates that include advanced chromatograms and mass spectrometry overlays. The process adapted over the years to prioritize documentation, but most improvements came from real, ground-level engagement with lab and plant teams.
For pharmaceutical and cosmetic inquiries, the highest level of transparency and testing support comes into play. Achieving this consistency at bulk scale calls for a mix of process rigor and cultural buy-in throughout the company. Regular third-party audits keep us alert to improvements—both in workflows and raw material sourcing. Over time, the push for data-rich, searchable documentation led our plant to adopt digital tracking across every stage of synthesis, purification, and packaging. This investment pays off: no more “lost” test records, better customer responsiveness, and smoother regulatory clearance.
The path from concept to finished 1-Bromodocosane isn’t always smooth or predictable. Long-chain alkyl bromides like this one behave differently from their mid-length cousins both during manufacture and final use. Understanding these subtleties only comes from years spent solving unexpected production challenges. The difference between a good product and a great one often rests in knowing how a batch will perform once it leaves the plant. Will it stir into a blend without clumping? Does it remain free from discoloration in heated transfers? The answers come from a mix of real-world results and a willingness to hear back from every customer, especially when the stakes run high.
Good communication with formulation chemists and plant operators at client sites has proven invaluable. Quick troubleshooting of transport, blending, or performance issues leads to long-term partnerships. Not every process scale-up goes as planned, and sometimes real adjustments are needed midstream. As a manufacturer, taking responsibility for each drum shipped builds trust and pushes us to continually improve. Direct feedback often highlights possibilities for product or process tweaks no lab trial would predict, allowing adaptation almost in real time.
The landscape surrounding specialty brominated intermediates continues to shift. Sustainability pressures keep increasing, and end users expect both performance and ethical stewardship. From day one, we focused on minimizing energy use, improving recovery and recycling of bromine, and switching to greener solvents where possible. The cost and complexity of these upgrades pays off over time—not only in market credibility, but in lower emissions, reduced waste, and fewer headaches with local regulations.
Long-chain alkyl bromides like 1-Bromodocosane will remain essential for next-generation surfactants, advanced lubricants, and critical pharmaceutical intermediates. Production methods must keep pace with both scientific and social expectations. For every ton produced, we weigh in on product lifecycle—where waste ends up, how to recover side streams, and how to certify a supply chain free from unethical practices. Our firm belief: the best way to maintain leadership is showing this level of ownership, not just for today’s orders, but for the future of industrial chemistry as a whole.
Manufacturing success doesn’t exist in a vacuum. It relies on an ongoing exchange of ideas with customers, regulators, and peers across the specialty chemical world. For 1-Bromodocosane, the technology behind modern production sits on decades of incremental improvements—each driven by real customer need. Whether adapting for cleaner processes, chasing higher purity for new regulatory regimes, or troubleshooting supply chain snags during global disruptions, this feedback loop drives us to keep improving our methods.
Ultimately, 1-Bromodocosane represents both a technical achievement and a commitment to responsible supply. Those who use the material for specialized synthesis—be it pharmaceuticals, surfactants, or advanced lubricants—demand more than a “by-the-numbers” chemical. They rely on steady quality, delivery you can plan around, and a partner willing to stand behind every drum. These aren’t abstract promises. They’re values rooted in years behind the controls, responding at midnight to the unexpected, and working collaboratively to shape the next generation of chemical possibility. That’s how lasting value is built—one batch, one customer interaction, and one trusted relationship at a time.