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1-Bromoanthraquinone

    • Product Name 1-Bromoanthraquinone
    • Einecs 202-083-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
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    Specifications

    HS Code

    969164

    Chemical Name 1-Bromoanthraquinone
    Molecular Formula C14H7BrO2
    Molecular Weight 287.11 g/mol
    Cas Number 82-86-0
    Appearance Yellow to orange crystalline powder
    Melting Point 195-198 °C
    Solubility In Water Insoluble
    Density 1.74 g/cm³
    Purity Typically ≥98%
    Smiles Brc1cccc2c1C(=O)c1ccccc1C2=O
    Inchi InChI=1S/C14H7BrO2/c15-9-6-2-4-8-12(9)14(17)11-7-3-1-5-10(11)13(8)16/h1-7H
    Synonyms 1-Bromo-9,10-anthraquinone
    Storage Conditions Store at room temperature in a tightly closed container
    Usage Intermediate for dyes, pigments, and pharmaceuticals

    As an accredited 1-Bromoanthraquinone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    Application of 1-Bromoanthraquinone

    Applications of 1-Bromoanthraquinone in Industrial Manufacturing

    With a controlled halogenation process, 1-Bromoanthraquinone provides a consistent and reliable raw material foundation for various high-value industrial sectors. Manufactured at commercial scale with traceable quality management, this compound enters downstream formulations where process-specific performance, regulatory conformance, and predictable reactivity are critical. The following sectors represent established, high-volume use cases verified by longstanding market demand and stringent industry oversight.

    1. Dye Intermediates for Anthraquinone-Based Synthetic Colorants

    As a core halogenated precursor, 1-Bromoanthraquinone serves the dye industry by introducing bromine functionality into the anthraquinone skeleton, enabling further substitution to create a range of anthraquinone dyes, such as disperse and vat colorants used for synthetic fibers and textiles. The compound is charged during the key intermediate stage, where accurate mole ratios and controlled thermal conditions assure color consistency, brightness, and fastness to light and washing. This application underpins high-speed continuous dye manufacturing lines supplying the textile finishing sector.

    Industry compliance standards

    • ZDHC Manufacturing Restricted Substances List (MRSL)
    • REACH Annex XVII and SVHC (Europe)
    • OEKO-TEX® Standard 100 (relevant for pigment residues in dyed fabrics)
    • ISO 9001:2015 certified dye production systems

    Typical usage ratio

    • 30–50 mol% relative to anthraquinone core, adjusted for target color and substituent patterns; process optimization considers yield and downstream coupling efficiency

    Downstream process integration

    • Charged as a primary halogen source in nucleophilic substitution, bromination, or condensation units; involved in continuous or batch reactor stages for synthesizing colorant intermediates

    Final product types

    • Disperse dyes for polyester and acetate fibers
    • Vat dyes used in cotton and cellulose printing
    • Sulfonated anthraquinone dyes for polyamide and blended fabrics
    • Pigment dispersions serving textile and plastics coloration

    2. Synthesis of Pharmaceutical Building Blocks

    Pharmaceutical intermediate manufacturers use 1-Bromoanthraquinone as a rigid aromatic building block to introduce specific functional groups into advanced intermediates, particularly in the production of antineoplastic agents and compounds requiring anthraquinone scaffolds. The material enters controlled organic synthesis lines, where strict trace analysis and containment govern its handling and processing. Downstream transformation—such as Suzuki coupling or nucleophilic aromatic substitution—tailors the molecule to meet the requirements for API (Active Pharmaceutical Ingredient) synthesis.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP–NF (United States Pharmacopeia–National Formulary) specifications for intermediates
    • EU EudraLex GMP Vol 4 Part II
    • FDA 21 CFR Part 210/211: Process controls for chemical synthesis

    Typical usage ratio

    • Determined by synthetic route; usually 1.0–1.3 molar equivalents per reaction batch, modulated for coupling efficacy and minimizing by-product formation

    Downstream process integration

    • Introduced during early or mid-stage build-up of the anthraquinone moiety; participates in stepwise functionalization or transition-metal-catalyzed coupling routes in multipurpose CGMP reaction suites

    Final product types

    • Precursors for anthracycline anticancer agents (e.g., doxorubicin derivatives, mitoxantrone intermediates)
    • Intermediates for anti-infective drug scaffolds
    • Molecules used in the synthesis of diagnostic probes containing anthraquinone cores
    • Fine chemical platforms for targeted drug discovery libraries

    3. High-Performance Organic Photovoltaic Materials

    Producers of organic electronic and photovoltaic materials utilize 1-Bromoanthraquinone as a functionalized building block to engineer polymer backbones and small-molecule acceptors for organic solar cells and photodetectors. The compound’s bromine atom facilitates post-polymerization modification and tailor-made energy gap tuning. Processing involves high-purity environments, and quality validation employs spectroscopic and chromatographic characterization before materials pass to device assembly or further functionalization.

    Industry compliance standards

    • RoHS Directive 2011/65/EU (for hazardous substance restrictions)
    • ISO 14001 Environmental Management System (relevant for electronic material plants)
    • Quality Management in R&D: ISO 9001:2015
    • IEC 61215 for photovoltaic module safety and durability (indirect impact on raw material selection)

    Typical usage ratio

    • 0.2–0.5 molar equivalents per polymer repeat unit, or up to 10 wt% in copolymer blend formulations based on device architecture requirements

    Downstream process integration

    • Charged into polymerization kettles or solution-phase organic synthesis lines for the preparation of functionalized donor-acceptor conjugated polymers or as a post-polymer modification feedstock

    Final product types

    • Organic thin-film solar cells (bulk heterojunction OPV modules)
    • Photodetector substrates for flexible electronics
    • Small-molecule semiconductors for sensor applications
    • Conductive organic coatings for electronic and display devices

    4. Advanced Paper Pulp Bleaching Catalysts

    In the pulp and paper industry, 1-Bromoanthraquinone functions as an efficient redox catalyst in alkaline pulping processes, specifically in the kraft pulping and peroxide bleaching stages. Its molecular structure enhances delignification kinetics, reducing kappa number while minimizing cellulose degradation. Large-scale operations dose the material directly into liquor streams or bleaching towers, ensuring process economics and product brightness prescribed by finished paper grades.

    Industry compliance standards

    • US EPA Cluster Rule for Pulp and Paper Manufacturing—Chemical Additive Regulations
    • ISO 12625 (Pulp, paper, and board testing requirements)
    • EN 647:2012 (Chemical resistance of pulps and papers—effects on finished goods)
    • Quality control per TAPPI T401 and T236 (Kappa number and chemical additives)

    Typical usage ratio

    • 1–10 ppm relative to dry pulp weight; dosage adjusted to wood species, pulp yield, and target brightness criteria

    Downstream process integration

    • Pumped into cooking or peroxide bleaching stages as a process catalyst; metered via chemical dosing systems interoperable with pulping continuous digester control software

    Final product types

    • High-brightness printing and writing paper
    • Bleached kraft pulp for hygiene paper production
    • Specialty grades for technical and laboratory papers
    • Premium packaging board

    5. Synthesis of Functionalized Agrochemical Intermediates

    Agrochemical manufacturers introduce 1-Bromoanthraquinone during custom synthesis of pest control agents and herbicides where an anthraquinone base structure forms the core of bioactive molecules. Its site-selective bromination enables late-stage diversification via substitution, offering tailored activity spectrum and improved field persistence. Plants administer rigorous process monitoring with in-process HPLC to track conversion efficiency and minimize unreacted halide residues in final downstream goods.

    Industry compliance standards

    • OECD Principles of Good Laboratory Practice (GLP) for test substances
    • FAO/WHO specifications for agrochemical raw materials
    • ISO 9001:2015 for chemical synthesis quality management
    • Regulatory listing in accordance with regional pesticide authority (EPA, ECHA, PMRA, ICAMA)

    Typical usage ratio

    • 0.5–2.5 molar equivalents depending on molecular substitution scheme; batch parameters set per target product’s regulatory MRL guidelines

    Downstream process integration

    • Fed into nucleophilic substitution or coupling reaction steps, enabling the formation of active ingredient cores within closed reactor networks designed for agrochemical intermediate production

    Final product types

    • Custom intermediates for selective herbicides
    • Miticide and fungicide active compound precursors
    • Plant growth regulator candidates with anthraquinone-based structures
    • Seed treatment formulation intermediates
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    Certification & Compliance
    More Introduction

    1-Bromoanthraquinone: A Modern Boost to Industrial Chemistry

    Setting the Stage for Innovation

    Every so often, something small changes the landscape for a lot of people behind the scenes. 1-Bromoanthraquinone makes an entrance in the world of specialty chemicals, and though it doesn’t get discussed over morning coffee, it matters to the industries that rely on smart chemistry. The anthraquinone scaffold has powered a lot of chemical progress across the years, anchoring dye production, intermediates for pharmaceuticals, and a host of other stories inside industrial labs. Now, adding a bromine atom at the right spot—a molecular tweak some see as routine—opens up opportunities that haven’t always been possible with other anthraquinone derivatives.

    What Sets 1-Bromoanthraquinone Apart?

    Plenty of compounds come and go, but not many keep surfacing as reliable building blocks in both classic and emerging technologies. A quick glance at 1-Bromoanthraquinone’s structure shows bromination at the 1-position, which might sound trivial but turns out to be a major differentiator from alternatives like 2-bromoanthraquinone or unmodified anthraquinone. In the hands of a chemist, location can equal opportunity. That bromine in the 1-position enables direct substitution reactions and cross-coupling in a way other anthraquinones can’t quite match. That means new routes to more complex molecules, dyes, pigments, and pharmaceuticals.

    Technical specs help, but from working with these molecules, consistency in purity tells the real story. Buyers often find 1-Bromoanthraquinone offered at purities exceeding 98%, with a melting point that settles around 183–185°C. Granular form or fine powder show up most, both easy enough to work with using standard lab techniques. Each producer may have small tweaks to their synthesis, but the heart of the compound remains constant: a reliable stepping-stone for advanced organic synthesis.

    More Than Just a Dye Intermediate

    Long journeys in industrial chemistry start with simple ideas. Anthraquinone dyes brought color where there was none, and the industry built a foundation with a handful of well-understood chemicals. 1-Bromoanthraquinone’s main draw still circles the dye and pigment market, where it acts as a core intermediate. By using the brominated version, color chemists can selectively create specific shades and tones, pushing the possibilities for printers, textile mills, and coatings that need lasting vibrancy. Yet, dye chemistry stopped being the only story years ago.

    In pharmaceutical synthesis, brominated anthraquinones open pathways for medicines that need anthraquinone’s backbone, but with delicate substitutions for activity or solubility. The pharmaceutical world rarely runs with unmodified templates; instead, each new therapy wants some customization. Medicinal chemists will recognize how useful a position-selective bromine substituent proves for further transformations—Suzuki couplings, for instance, rely on that feature to join larger, more complex fragments with high precision.

    Moving beyond what’s expected in the dye and pharmaceutical sectors, 1-Bromoanthraquinone finds its way into research projects aiming at organic electronics. Researchers working on functionalized molecules for photovoltaic materials and semiconductors look for building blocks exactly like this one, ready to undergo detail-oriented chemical reactions and form the centerpiece of bigger, more complicated devices.

    Everyday Experience with Specialty Chemicals

    Most people never see a drum of 1-Bromoanthraquinone. In my years writing and talking to folks in the chemical supply chain, the thread that runs through the best producers is a focus on the actual use. Even if 99% of the world doesn’t care, the handful who do genuinely depend on access to high-purity batches and predictable deliveries—there’s nothing worse than being halfway through a production campaign just to learn the latest lot contains a percent or two of unexpected byproducts. That attention to quality isn’t just for lab convenience; it saves companies the headache of troubleshooting batches and reworking processes.

    I’ve heard from dye chemists that batch-to-batch consistency isn’t about perfection, but about trust. If you’ve ever had to recalibrate a process due to a slightly impure intermediate, you’ll know what I mean. Errors at the level of a substituent on an anthraquinone don’t sound dramatic, but they add up to color shifts, batch failures, paperwork, and lost time. Working with reputable suppliers, the end-user can plan their process with fewer surprises, which is a rare luxury in industrial work.

    Comparing to Other Options: A Closer Look

    A lot of progress in organic synthesis depends on creative adaptation. Anthraquinones pop up in dozens of roles—redox catalysts, pharmaceutical scaffolds, coloring agents. Yet placing the bromine at the 1-position does more than adjust its reactivity; it delivers options. Other halogenated anthraquinones, like the 2-bromo or chloro derivatives, exist too, but each shows its quirks. Some react less smoothly, others cost more, or introduce difficulties in purification.

    Online forums and peer-reviewed studies keep surfacing evidence that 1-Bromoanthraquinone strikes a cost-versus-versatility balance that alternative intermediates miss. Sourcing 2-bromoanthraquinone can prove more expensive and sometimes more hazardous, while simple anthraquinone often lacks the reactivity needed for the fast-moving reactions today’s process chemists need. In practice, 1-Bromoanthraquinone manages to avoid the drawbacks seen with other brominated or alkylated derivatives: fewer purification headaches, lower byproduct formation, and high yields in the key coupling reactions that matter for scale-up.

    Anyone who’s spent time in industrial synthesis knows the sad story of route modification: swapping out an intermediate can trigger a domino effect, changing solvents, temperatures, and safety procedures throughout a plant. With 1-Bromoanthraquinone, the ability to use off-the-shelf procedures gives process chemists breathing room when deadlines approach and budgets feel tight. It’s a relief to be able to refer to established literature and trusted reaction pathways instead of flying blind.

    Sustainability and Safety in Modern Practice

    Working with brominated aromatics always means keeping an extra eye on operations. Safety matters; waste management matters. Having spent time in plants where managing halogenated waste is routine, there’s no pretending that these compounds are “green.” Still, the story changes compared to multi-halogenated alternatives or more toxic halogen donors. Where the process can run with minimal waste, and where the bromine remains tightly bound until needed, risks stay manageable.

    A trend is building for more sustainable sourcing and lower-impact byproducts, and 1-Bromoanthraquinone sits in a sweet spot between performance and practicality. Producers with experience deliver reliable supply without the surprises that come from buying inconsistent material from unknown sources. Quality controls, traceable lots, and better safety documentation all bring peace of mind, especially in sectors facing regulatory scrutiny.

    The Real Impact on Production and Research

    Modern research groups and process engineers rarely want just a single solution; they keep eyes out for flexible options that translate well from gram to kilogram scales. Over the last few years, I’ve watched a gradual but steady increase in interest from research teams diving into advanced organic materials—optoelectronics, sensor molecules, specialty ligands. They look for reliability above all else. 1-Bromoanthraquinone, with its well-understood reactivity and documented uses in the major chemical literature, supports the sort of modular chemistry strategies that make career-defining discoveries possible.

    Every time a new specialty dye or high-performance pigment is launched, someone behind the scenes has wrestled with intermediates like 1-Bromoanthraquinone. The molecule may look unassuming but ends up part of innovations that drive industries forward. Countless process patents use it as a named intermediate; it’s a familiar face for those in the know.

    In my own talks with chemists focused on new materials, the common thread is how much time robust intermediates save in troubleshooting and optimization. When your focus is launching something new, the last thing you want to handle is inconsistent starting points.

    Supply Chain Realities and Market Trends

    Markets go through boom-and-bust cycles. Over the years, anthraquinone-based intermediates saw dramatic shifts in pricing and regulatory attention. In my experience, suppliers committed to transparency and regular testing always win out, especially as environmental rules tighten and end-users demand more complete documentation.

    Recent global events put stress on supply chains, spotlighting the need for strong relationships with suppliers who know both the molecule and the market. 1-Bromoanthraquinone doesn’t just travel from plant to lab; it carries expectations—purity, batch size, safety profile, delivery timeline. The most reliable sources either manufacture locally or guarantee chain-of-custody, so buyers know what they’re getting and how it’s been handled. That’s not marketing talk—that’s stress saved during audits and regulatory checks.

    With the world’s appetite for synthetic dyes and active pharmaceutical ingredients still growing, established intermediates like this one become a foundation for flexibility. Research teams and production planners can pivot faster when they start from dependable building blocks. I’ve seen organizations falter on projects because some detail in the supply chain didn’t hold up; the right intermediate, in the right place, acts as an insurance policy.

    Future Directions and Challenges

    Innovation in chemistry doesn’t slow down, so neither do the intermediates. Researchers continue to push for faster syntheses, cleaner routes, and safer production. 1-Bromoanthraquinone will only keep its edge if the community behind it invests in better processing, greener byproducts, and more transparent reporting. Some labs already explore milder bromination methods or adopt alternative solvents to minimize waste, and these efforts deserve wider recognition and support.

    The biggest hurdle for newcomers isn’t usually the chemistry—it’s the standards. Whether it’s the latest pigment or pharma project, regulations shape the playing field. Batch records, certifications, residue testing, and export documentation all matter. Experienced suppliers know this terrain and have adapted their pipelines to clear the hurdles.

    For early-stage startups or academic teams, engaging suppliers willing to communicate openly and explain their controls saves time and effort. Working with compounds like 1-Bromoanthraquinone becomes less of a gamble and more of a collaboration.

    Practical Solutions for Everyday Users

    The future for specialty chemicals rests on adaptation. There’s a strong need for more routine testing for impurities—not just the headline figure, but trace metal analysis and identification of possible side-products. Industry groups can step in to develop standardized protocols for these checks, making the market safer and reducing the risk of failed batches.

    Scalability matters too. Most pilot processes start small, but moving to production scale reveals issues that were invisible before. Heat management, mixing speeds, and waste neutralization—tiny details that separate robust intermediates from theoretical curiosities. Training plant technicians and analysts to recognize and anticipate problems with brominated intermediates will keep quality high and minimize disruptions.

    Another solution sits in digitalization. Supply chain databases and batch tracking systems cut down on the legwork needed to ensure material quality. I’ve talked with engineers and scientists who have moved to cloud-based QC logs; they spend less time digging for paper records and more time improving their outputs. This approach also fits the growing calls for traceability and environmental reporting being requested by regulators and customers in Europe and North America.

    Wrapping Up the Practical Value

    On paper, 1-Bromoanthraquinone is a simple chemical tweak—a single bromine at a fixed location on an old anthraquinone backbone. That change, though, makes a real difference for industrial processes that live or die on reliability. From dyes to drugs and materials science to electronics, its role has grown, shaped not by marketing but by the trust and consistency earned through careful production and steady improvement.

    Looking forward, users at every scale—from bench chemists to plant operators—stand to benefit from suppliers who treat documentation, testing, and customer support as seriously as the chemistry itself. More transparency, stronger supply chains, and continued innovation will guarantee that 1-Bromoanthraquinone keeps its place at the center of essential discoveries and industrial milestones for years to come.