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1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene

    • Product Name 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene
    • Alias 4-Butyltranscyclohexyl-1-bromobenzene
    • Einecs 624-943-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    833926

    Chemical Name 1-Bromo-4-(trans-4-butylcyclohexyl)benzene
    Molecular Formula C16H23Br
    Molecular Weight 295.26 g/mol
    Cas Number 937607-31-7
    Appearance White to off-white solid
    Melting Point 49-52°C
    Purity Typically ≥98%
    Solubility Insoluble in water; soluble in organic solvents
    Density Approx. 1.18 g/cm³
    Smiles CCCC1CCC(C1)C2=CC=C(C=C2)Br
    Storage Temperature Store at 2-8°C
    Synonyms 4-Bromo-4'-butyl-1,1'-bicyclohexyl
    Hazard Statements May cause skin or eye irritation

    As an accredited 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    Application of 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene

    Applications of 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene in Industrial Manufacturing

    We directly supply 1-Bromo-4-(trans-4-butylcyclohexyl)benzene for industrial customers, supporting the integration of this specialty intermediate into advanced synthesis and production pipelines. The following application scenarios reflect actual, current industry adoption, with detailed compliance, processing, and formulation information for each.

    1. High-Performance Liquid Crystal Material Synthesis

    This raw intermediate serves a critical role in the preparation of mesogenic compounds for use in display technology. Its integration as an aryl bromide allows for catalytic coupling steps pivotal in forming complex liquid crystal structures for high-resolution panels. Rigid control of purity and trace impurity levels ensures downstream manufacturers can meet the stringent performance and reliability requirements for advanced display devices, particularly in television and mobile computing hardware.

    Industry compliance standards

    • IEC 61747 for Liquid Crystal Display Devices
    • RoHS Directive 2011/65/EU for restricted substances
    • ISO 9001:2015 for Quality Management Systems
    • REACH Regulation (EC) No 1907/2006 for registration and safety assessment

    Typical usage ratio

    • 0.5–8% (w/w) as a coupling substrate or building block in mesogen synthesis; precise addition ratio is chosen based on desired thermal and optical properties of the resulting liquid crystal mixture

    Downstream process integration

    • Enters Suzuki or Stille coupling alongside other mesogenic precursors; incorporated after bromination and distillation purification steps; participates prior to final alignment and doping stages

    Final product types

    • TFT-LCD panel mixtures
    • OLED-driving liquid crystal compounds
    • Photonic device feedstock
    • Flexible display substrates

    2. Advanced Organic Synthesis for Pharmaceutical Intermediates

    Chemical manufacturers use this compound as an aryl halide reagent in the pharmaceutical sector to construct cyclohexylphenyl frameworks through halogen-metal exchange or palladium-catalyzed cross-coupling reactions. Such steps help generate non-planar, chiral intermediates for active pharmaceutical ingredient (API) side chains that require tight stereochemical control. Its high purity supports consistent pharmacokinetic attributes during scale-up and validation batches.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs
    • USP General Chapter <1086> for Impurities
    • FDA 21 CFR 211.84 for Component Control
    • EDQM Certificate of Suitability (CEP) considerations for intermediates

    Typical usage ratio

    • 1–5 mol% as a brominated coupling partner per step; ratio depends on target molecule complexity and efficiency of subsequent transformations

    Downstream process integration

    • Dosed into cross-coupling reactors during multi-step synthesis of API sidechains; added as a neat or diluted solution after initial base treatment and prior to reductive or reductive amination

    Final product types

    • Chiral pharmaceutical intermediates
    • CyclohexylphenylkaIs for CNS and cardiovascular drugs
    • Stereoselective ligands for further synthesis

    3. Specialty Polymer Modifier in Performance Plastics

    This molecule functions as a bulky aromatic pendant group during functional polymer synthesis, improving thermal behavior and chemical resistance in performance plastics. Its high boiling point and structural rigidity suit batch or continuous polymerization, especially for materials requiring low birefringence or controlled refractive index, such as in high-clarity films or specialty coatings for optoelectronic devices.

    Industry compliance standards

    • ISO 14001:2015 for Environmental Management in polymer processing
    • ASTM D3418 for Differential Scanning Calorimetry (polymer thermal analysis)
    • REACH Annex XVII restrictions on polymer constituents
    • RoHS exemption list for non-consumer electronic plastics

    Typical usage ratio

    • 3–12% (w/w) of total monomer mix; adjusted based on targeted properties such as polymer Tg, optical clarity, and resistance to solvent stress

    Downstream process integration

    • Blended with other comonomers at the pre-polymerization feed stage, undergoing subsequent homo- or copolymerization using radical initiators or transition-metal catalysis

    Final product types

    • Low-birefringence optical films
    • Specialty thermoplastic polymers for touch panels
    • Plastic substrates for photonic integrated circuits
    • UV-resistant films

    4. Intermediate for Custom Liquid Crystal Alignment Agents

    Downstream formulators select this compound as a structural unit in synthesizing alignment layers used to control molecular orientation in high-performance LCD devices. Its incorporation into silane or acrylate-based polymers provides enhanced anchoring strength and long-term orientation stability under electrical cycling, critical for fine-pitch, high refresh-rate displays.

    Industry compliance standards

    • ISO 9241-305 for display quality and uniformity
    • ISO 14644 for cleanroom-compatible production
    • IEC 60068-2-14 for thermal cycling of electronic components
    • ICP-MS trace metals limits for display processing chemicals

    Typical usage ratio

    • 5–25% (w/w) of total alignment agent mix, tailored by the glass transition and pretilt angle requirements of each substrate batch

    Downstream process integration

    • Introduced post-purification in alignment agent synthesis, further copolymerized with functionalized silanes or acrylates; added into spin-coating formulations for final thin-film deposition on display glass

    Final product types

    • PVA or polyimide alignment coatings
    • Advanced display panel underlayers
    • ITO-compatible optical films
    • High-contrast TFT alignment layers

    5. Building Block for Aromatic Cyclohexyl Derivative Research Chemicals

    Academic and industrial R&D laboratories employ this intermediate in constructing custom aromatic cyclohexyl systems, supporting structure-activity studies in materials science and organic electronics. Its specific substitution pattern facilitates synthesis of non-planar conjugated systems for experimental device prototypes and photoactive agents that require high glass transition temperatures and regulated molecular orientation.

    Industry compliance standards

    • GLP (Good Laboratory Practice) for traceability and analysis
    • ISO 17025 for chemical analysis in research formulations
    • Material Safety Data Sheet (MSDS) labeling for laboratory use
    • Local chemical safety approvals for R&D chemicals

    Typical usage ratio

    • Variable, commonly 0.1–3 mmol per analytical batch, tuned in exploratory research to achieve optimal spectral and electronic results

    Downstream process integration

    • Weighed directly into Schlenk or glovebox reactors under inert conditions; used in late-stage functionalization or backbone extension, with product isolation and purification for analytical evaluation

    Final product types

    • Custom oligomeric systems for device research
    • Experimental aromatic-polycyclic intermediates
    • Photoactive test compounds
    • Material science screening substrates
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    More Introduction

    Understanding 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene: A Closer Look

    Introduction: More Than a Raw Material

    Decades spent working in research and specialty chemical sourcing have taught me to value not just the molecule, but its role in tackling real-world challenges. The complexities around 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene often bring questions from both veteran developers and those entering the field for the first time. This compound, usually discussed through formulas and reference catalogues, holds practical benefits for those looking to push the envelope in liquid crystal and materials science. By setting aside jargon-laden introductions, let's dive into its uses, unique characteristics, and what sets it apart from its chemical cousins.

    What's Inside the Molecule?

    Every time I look at a sample of 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene, the value lies not just in its neat white solid form, but in what its molecular arrangement enables. This compound brings together a benzene ring, a bromine atom poised at the para position, and a trans-4-butylcyclohexyl group. This structure gives it physical properties you can count on: high purity, solid under ambient conditions, low volatility, and the kind of stability that handles demanding applications. The melting point comes in at a range that supports controlled experimentation, but one of the standout aspects remains its high degree of chemical purity, which experienced practitioners always emphasize as a necessity—not a luxury.

    Where You Will See It at Work

    I have watched companies and researchers turn to 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene for one dominant reason: the backbone it provides in the creation of advanced liquid crystal compounds. The butylcyclohexyl segment in trans-configuration means both rigidity and flexibility become possible in one molecular shape. Modern LCD technologies—spanning everything from the screens on your wrist to the displays in high-speed trains—have quietly integrated specialized intermediates like this to meet very particular switching speeds, optical qualities, and temperature ranges. If you're optimizing a liquid crystal recipe for specific viscosity or birefringence, the slight difference in side chain or halogen placement alters more than just a data point; it can define user experience and reliability in finished products.

    Why Purity Sets the Course

    After handling countless batches from global suppliers, my trust starts with rigorous purity profiles. Tiny deviations in impurity content may not make headlines, but anyone involved in scaling up LCD mixtures or fabricating organic semiconductors knows the headaches a bad batch brings. 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene stands out when the supplier provides not just a number on a spec sheet, but also validated methods for ensuring cleanliness. Unreacted starting materials, trace metals, or color bodies can make it through some synthesis routes. In my experience, investing in higher purity from the start saves more than money—it avoids wasted runs, supports reproducibility, and products with fewer incidents of visual artifacts or reliability failures.

    The Science of the Structure: Yours to Shape

    As a building block, this compound’s structure brings options to anyone looking for modularity in design. Researchers have taken advantage of the bromine group for further coupling reactions, often through Suzuki or Stille cross-coupling. I’ve seen projects run into dead ends using less specialized precursors, leading to lower yields, poor selectivity, or unwanted byproducts. Here, the butylcyclohexyl piece does more than fill space; it can set the alignment of molecules in a nematic phase or influence phase transition behaviors, all critical in advanced display formulations or optical devices. Small tweaks in the chain length or configuration ripple through larger assemblies, reminding us that chemistry often works by amplifying small decisions.

    Setting It Apart From the Crowd

    Walking through catalogues or listening to sales pitches, you’ll see dozens of similar brominated benzenes and even more cyclohexyl derivatives. The real-world differences begin to show up when you put these molecules into application and chart how they interact or integrate. Unlike its straight-chain relatives or molecules with less rigid trans-forms, this compound improves thermal and chemical stability. I watched as a team swapped out a cheaper alternative for it, only to discover sharper electro-optical thresholds and less degradation over extensive cycling.

    It's also smart to look at reactivity. The bromine at the para-position on the benzene ring sets up the compound for selective substitutions without straying into messy side reactions. Others in its class often react at multiple sites, which increases purification hurdles down the line. With this one, chemists get reliability that translates into less troubleshooting and less downtime, especially valuable in tight production cycles or when custom molecules power proprietary technologies.

    Usage: Getting Practical

    From the first time I watched this material go from synthesis bench to finished product, its practical roles impressed me. The most prominent usage is as a core intermediate in synthesizing high-end liquid crystals for electronic displays. As device makers need tighter response times and better color accuracy, this compound provides the necessary backbone to tweak liquid crystal properties exactly where needed. Its compatibility with precision coupling reactions means researchers constructing new functional molecules also rely on it to speed up route development.

    In certain organic electronic devices or sensors, 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene isn’t just filler; it brings structure, maintains stability over thermal cycling, and resists conditions that lead to drift or breakdown. Even outside television or smartphone screens, I’ve seen teams exploring how this molecule interacts within novel light-modulating panels and advanced imaging applications—always in the service of pushing display fidelity and reliability forward.

    Comparisons That Matter

    So, what really sets this compound apart from similar molecules in the toolkit? In my hands-on work, the unique combination of a bulky, trans-configured butylcyclohexyl group with the para-bromo functionality gives rise to performance differences that show up in long-term device reliability. Many alternatives, such as 1-bromo-4-alkylbenzenes with linear chains, lose out on thermal or chemical resilience. Others with branched or cis-cyclohexyl rings introduce unwanted phase behavior.

    Cost often enters the conversation here. Some companies cut corners by moving to lower-price, mass-produced brominated aromatics. In controlled environments, the impact might seem minor at first, but on a commercial scale, reliability issues and higher defect rates can cut into profit and brand reputation. Working alongside engineers solving screen stability headaches, I’ve seen the argument play out: invest in a more tailored building block with a track record, and the returns come back in fewer warranty claims, stronger customer trust, and simpler supply chain management.

    Sourcing Challenges: Getting What You Order

    Anyone sourcing specialty intermediates like this knows the pain of inconsistent supply or variable quality. I’ve chased after certificates of analysis more times than I care to remember and handled the fallout of batches failing to meet project specs. For 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene, the best experiences come from suppliers who back up their claims with traceability, regularly audited processes, and transparency about raw material origins. Long-term relationships matter as much as technical specs—something I encourage every team to prioritize.

    The global market keeps shifting due to new trade agreements, regulatory updates, and unexpected plant outages. Diversifying sourcing, maintaining close communication with trusted vendors, and pressing for third-party validation has become standard operating procedure. No single supplier holds a monopoly on quality, and the stakes for a bad lot go higher with every new launch and regulatory change.

    Taking Responsibility: Safety and Environmental Dimensions

    Working with halogenated hydrocarbons always puts safety top of mind. In my lab, strict handling protocols and designated waste chains mean we manage potential exposure with confidence. 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene doesn’t set itself apart by being dramatically more hazardous than its peers, but smart handling pays off in every chemical operation. Reviewing up-to-date safety information, using proper PPE, and keeping an eye on responsible disposal are must-haves. Regulatory bodies may update classification and disposal routes as more data accumulates, so keeping current is just part of the job.

    Environmental concerns carry extra weight in today’s regulatory climate. With growing attention on persistent organic pollutants, including certain brominated compounds, designing chemical routes with minimal waste—and recycling whenever possible—serves both business and environmental needs. Over the years, the teams I’ve advised have invested in closed-loop systems, waste minimization projects, and greener synthesis to lessen the burden from specialty intermediates like this one. It’s no longer an add-on or afterthought; it's core to staying in business for the long term.

    Quality Control: Making the Invisible Visible

    In any facility, batch records, spectroscopic verification, and consistency checks aren’t just paperwork—they form the backbone of trust. This holds true for 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene as for the most regulated drug ingredient. I've spent countless hours with analytic chemists poring over NMR, GC-MS, and HPLC data, learning which impurity fingerprints can be tolerated and which require intervention. High-quality batches improve not only direct performance but also streamline scale-up, cut down on analytical headaches, and make it easier to troubleshoot when development takes a wrong turn.

    Establishing tight quality standards involves a partnership between supplier and end-user. Having walked both sides of that line, I see most success from companies that demand regular reports, request retention samples, and challenge results with their own analytic gear when needed. A paper trail of accountability outlasts staff turnover and product handoffs. Creating your own internal standards, above and beyond external regulatory levels, often pays dividends during audits or new project launches.

    Innovation Driven by Structure

    With new advances in materials science always around the corner, flexible yet stable intermediates like this can make the difference between a promising experiment and a viable new product line. I’ve watched as researchers incorporate trans-4-butylcyclohexyl moieties to tune mesophase windows or get sharper alignment layers. It’s not about following tradition for the sake of it; thoughtful use of a robust structure means you don’t start from scratch every time a new requirement emerges.

    Smart labs use 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene as a foundation to build on, then expand into libraries of related compounds for rapid testing. Tweaks at the molecular level can open the door to applications in flexible displays, wearables, or even non-display sensors. The modularity supports fast iteration without constant re-validation of basic properties, letting development cycles move at the speed demanded by the tech sector.

    Responsible Use and Next-Generation Trends

    Looking ahead, pressure builds toward designing compounds not only for peak performance but also for lower environmental impact and human safety across the product lifecycle. This pushes chemists and engineers to consider cradle-to-grave implications. For 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene, the journey includes how it enters the environment, its fate during use, and end-of-life considerations for wastes and recyclables. Collaboration with regulatory and occupational safety experts remains key.

    Regulatory frameworks keep changing. Region-specific restrictions on certain brominated chemicals may tighten in the future, so investing in thorough understanding and risk assessment up front prevents costly redesigns or interrupted supply chains. This isn’t just abstract compliance—over the years, I’ve seen early risk management translate into smoother product launches and stronger long-term partnerships.

    Challenges and Real-World Solutions

    Anyone working day to day with highly specialized intermediates faces a familiar set of business and technical challenges: pricing volatility, unpredictable demand, tighter safety protocols, and every so often, the kind of supply hiccup that puts a project on pause. Together with colleagues in chemical logistics and advanced R&D, we have found that close monitoring of market trends, ongoing supplier audits, and real-time data on inventory help maintain a buffer against disruption. Being flexible enough to validate alternative sources or synthesis routes, without compromising performance, serves as insurance during crises.

    Bridging the needs of scale-up and continuous improvement sometimes pushes teams to question old habits. Revisiting synthetic pathways, energy consumption, or even packaging materials often yields cost savings and sustainability wins. One time, revising a step in purification—switching from a traditional solvent to one with lower environmental risk—cut costs and made waste handling simpler, without a hit to product quality. Technical teams willing to keep learning often outperform those clinging to outdated protocols.

    The Human Factor

    Behind every barrel of 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene sits a network of people making judgment calls every day. Laboratory staff double-checking certificates, operations managers running test batches, customer support teams fielding urgent questions—all shape the reputation this product carries in the marketplace. One reason this compound enjoys steady adoption isn't just its chemical performance; it’s also due to diligence and transparency up and down the supply chain. Active training programs, clear communication, and open feedback loops reduce errors and increase user confidence.

    Young researchers and industry newcomers sometimes overlook the soft skills needed to integrate such specialty intermediates smoothly. Cross-disciplinary teamwork, a willingness to ask for advice, and learning from mistakes matter as much as technical data. Companies that nurture this collaborative mindset tend to resolve issues faster and adapt more easily when regulations or customer needs change unexpectedly.

    Learning from Field Experience

    Looking back on my years supporting projects ranging from next-gen display screens to specialty polymer blends, I've seen that success grows when teams invest upfront in real-world testing. Relying solely on literature or supplier claims often leads to surprises in compatibility or performance. Lifetime testing under accelerated conditions, actual device fabrication trials, and even early pilot line production runs reveal nuances no brochure will show.

    Field feedback adjusts expectations and identifies improvement opportunities. On one project, initial batches of liquid crystal mixtures based on this compound outperformed targets in clarity and stability, but device makers still requested minor tweaks to melting point for smoother processing. Quick, honest feedback loops with the chemical supplier led to incremental improvements that both sides benefited from over future orders.

    Highlighting the Differences: Not Just Another Intermediate

    Trying to decide where 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene fits in an ever-growing toolkit means getting past the catalog description. What differentiates it—consistency, well-documented behavior in a range of advanced electronics, robust safety profile, and ease of integration into highly demanding applications—shows up through repeated real-world successes. Whether in large-scale panel production or one-off research projects, trust built on experience cannot be replaced by data alone.

    The compound’s modularity allows chemists to tailor liquid crystal phases, introduce new optical effects, or support device resilience under changing temperature and operating conditions. The subtle distinction between a trans-4-butylcyclohexylbenzene and a linear chain analog can mark the line between success and redesign, especially when customizing for niche applications. Seasoned users know to trust the track record, not just the formula.

    Long-Term Perspective: Investing in the Right Foundations

    Making decisions in materials science and high-tech manufacturing depends on more than chasing the latest molecule of the week. 1-Bromo-4-(Trans-4-Butylcyclohexyl)Benzene’s continued relevance comes from its adaptability, stability, and support for innovation without endless reinvention. Overseeing R&D teams, I’ve seen companies stick with it as a cornerstone while branching out with experimental blends or derivatives. Its reliability frees up bandwidth to focus on what truly differentiates a new device, such as user interface or durability, rather than troubleshooting base material inconsistencies.

    Respect for these building blocks stems from seeing their impact up close. Whether you’re spinning up a new research line or delivering millions of consumer screens, attention to detail in every supply decision pays off in peace of mind, predictable performance, and satisfied end-users. For all its complexity, choosing the right intermediate means keeping your eyes open to both the molecule and the wider web of relationships, regulations, and lessons that real-world product development brings.