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1-Bromo-2-Iodotetrafluoroethane

    • Product Name 1-Bromo-2-Iodotetrafluoroethane
    • Alias Halon 2402
    • Einecs 700-896-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    550157

    Chemicalname 1-Bromo-2-Iodotetrafluoroethane
    Molecularformula C2BrF4I
    Molarmass 355.825 g/mol
    Casnumber 354-06-5
    Appearance Colorless liquid
    Boilingpoint 72°C
    Density 2.58 g/cm³
    Solubilityinwater Insoluble
    Refractiveindex 1.425
    Smiles C(C(F)(F)I)(F)(F)Br
    Meltingpoint -9°C

    As an accredited 1-Bromo-2-Iodotetrafluoroethane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g amber glass bottle with tamper-evident cap; features clear labeling detailing chemical name, hazard symbols, and handling precautions.
    Shipping 1-Bromo-2-Iodotetrafluoroethane is shipped as a hazardous chemical under appropriate regulations. It must be packaged in tightly sealed, compatible containers, labeled according to international transport standards (such as UN codes), and kept away from sources of heat and ignition. Specialized documentation and handling by trained personnel are strictly required during shipping.
    Storage 1-Bromo-2-iodotetrafluoroethane should be stored in a tightly sealed container under cool, dry, and well-ventilated conditions. Keep it away from sources of ignition, direct sunlight, and incompatible substances such as strong bases and oxidizers. Store in a designated chemical storage area with proper labeling, and ensure secondary containment to prevent leaks or spills. Handle with appropriate personal protective equipment.
    Application of 1-Bromo-2-Iodotetrafluoroethane

    Applications of 1-Bromo-2-Iodotetrafluoroethane in Industrial Manufacturing

    As a direct manufacturer, we support multiple specialized industrial sectors with 1-Bromo-2-Iodotetrafluoroethane, addressing unique chemical requirements for synthesis, material performance, and regulatory compliance. Below, we detail several critical use cases in real downstream applications.

    1. Pharmaceutical Intermediate Synthesis

    Pharmaceutical companies utilize this material during halogen exchange and molecular modification steps to introduce select fluorinated and halogenated motifs into complex molecules. Its specific reactivity profile allows for controlled single-step or sequential modifications in the synthesis of APIs that require fluorinated building blocks, often under strictly validated process conditions in accordance with regulatory filings.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia 11th Edition (EP 11.0) reference monographs
    • US FDA 21 CFR Part 211 for finished pharmaceuticals
    • REACH Regulation (EC) No 1907/2006 compliance for chemical substances

    Typical usage ratio

    • Applied at 0.5–2.0 molar equivalents relative to active intermediate. Ratio depends on target fluorination level; process development sets exact dosing based on conversion efficiency and impurity control.

    Downstream process integration

    • Enters the synthesis route at the halogenation or perfluoroalkylation step following base molecule preparation. Reaction monitored for halogen incorporation and excess quenching before purification.

    Final product types

    • Fluorinated active pharmaceutical ingredients (APIs)
    • Bioactive pharmaceutical intermediates for oncology, neurology, and anti-infective drugs
    • Advanced intermediate libraries for medicinal chemistry screening

    2. Specialty Agrochemical Manufacturing

    Producers of crop protection agents leverage the unique halofluorocarbon structure for constructing herbicide and fungicide molecules with robust environmental persistence and specific biological activity. The compound provides a stable precursor component within multi-stage syntheses, particularly for next-generation fluorinated agroactives focused on improved plant selectivity and metabolic resistance.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals, Section 1 (Physico-chemical properties and transformations)
    • FAO/WHO JMPR recommendations for residue analysis
    • ISO 17025:2017 for quality control in analytical laboratories
    • National agrochemical registration requirements in major markets (EPA, EFSA)

    Typical usage ratio

    • Typically 1.0–5.0% by mass in intermediate reaction step. Actual percentage determined through trial synthesis considering byproduct formation and active loading in final product.

    Downstream process integration

    • Introduced during the molecular scaffold elaboration phase, often after aromatic substitution. Post-reaction, purification isolates target fluorinated precursors, feeding directly into coupling or formulation stages.

    Final product types

    • Fluorinated herbicide compounds engineered for key row crops
    • Fungicide active substances with enhanced stability
    • Intermediates for synthesis of environmental degradation-resistant pesticides

    3. Electronic Chemicals for Semiconductor Processing

    Advanced semiconductor fabrication facilities require ultra-high-purity halofluorocarbons for plasma etching and vapor phase deposition steps. This material functions as a precision etchant in integrated circuit (IC) manufacturing, permitting fine control over silicon substrate surface modulation and oxide layer definition. Its well-defined vaporization characteristics and consistent chemical fingerprint meet microelectronics-grade purity needs.

    Industry compliance standards

    • SEMI C3-0320 (Specifications for Gases Used in Photovoltaic, IC, and MEMS processes)
    • QS-9000 / IATF 16949 for supply chain quality management in electronics manufacturing
    • RoHS Directive 2011/65/EU for hazardous substances restrictions
    • F-Gas Regulation (EU) 517/2014 for fluorinated greenhouse gas handling

    Typical usage ratio

    • Injected at 0.2–0.8% of total plasma gas mixture; process engineers adjust concentration based on target etch rate, desired selectivity, and wafer batch scale.

    Downstream process integration

    • Directly fed into vacuum plasma reactors during anisotropic silicon etching and oxide patterning. Monitored closely for exhaust byproduct control and chamber conditioning intervals.

    Final product types

    • Etched silicon wafers for logic and memory ICs
    • Microelectromechanical systems (MEMS) substrate components
    • Photovoltaic cell elements requiring fine feature etching

    4. Refrigerant and Heat Transfer Media Synthesis

    Chemical companies engaged in specialty refrigerant and high-performance heat transfer fluid production use this compound as a precursor for formulating new-generation HFCs and HFOs. Its molecular architecture allows for subsequent hydrofluorination or halogen exchange steps, yielding final molecules with designed thermal properties and low global warming potential, in line with tightening climate regulations across key industrial regions.

    Industry compliance standards

    • ASHRAE Standard 34 for refrigerant safety classification
    • ISO 817:2014 Refrigerants — Designation and Safety Classification
    • UL 60335-2-40 for electrical heat pump and air-conditioning equipment
    • Kigali Amendment protocols to the Montreal Protocol (phase-down of HFCs)

    Typical usage ratio

    • Used at 3–10 mol% of initial reaction mixture in fluorination stages. Actual ratio set by targeted thermodynamic properties and molecular chain length of output product.

    Downstream process integration

    • Feeds into dehalogenation or chain extension reactors for generation of custom refrigerant blends. Intermediate composition checked by GC-MS before downstream distillation and purification.

    Final product types

    • Hydrofluorocarbon (HFC) refrigerants with application in industrial chillers and climate control
    • Hydrofluoroolefin (HFO) low-GWP refrigerants for next-generation thermal systems
    • Blended heat transfer fluids for electronics thermal management and process cooling

    5. Advanced Materials and Polymer Modification

    Manufacturers of specialty polymers and engineered materials rely on the unique halogen and fluorine content of this compound for molecular-level modifications, imparting hydrophobic, chemical-resistant, or dielectric properties. The material serves in copolymerization and reactive extrusion, particularly where tailored surface energy or response to electromagnetic fields is critical, such as in wire insulation, aerospace composites, and protective coatings.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for advanced material processing
    • UL 94 (Flammability of Plastic Materials for Parts in Devices and Appliances)
    • ASTM D543 (Resistance of Plastics to Chemical Reagents)
    • REACH/TSCA record-keeping for polymer additives and monomer substances

    Typical usage ratio

    • Blended at 1–7 weight % in specialty polymer feedstock or reactive extrusion systems. Adjusted according to required functional group incorporation and property targets in end-use application.

    Downstream process integration

    • Fed into mixer or extruder prior to final polymerization or crosslinking. Monitored through FTIR and chromatography for successful incorporation and residual unreacted species removal.

    Final product types

    • Fluorinated wire and cable insulation
    • Chemical-resistant coatings for industrial equipment
    • Composite laminates for aerospace and automotive applications
    • Smart sensor encapsulation and insulation materials
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    Certification & Compliance
    More Introduction

    1-Bromo-2-Iodotetrafluoroethane: Chemistry in Action

    Our View from the Factory Floor

    Every specialty chemical brings a personality to the table, and 1-Bromo-2-Iodotetrafluoroethane stands out with its unique chemical backbone. Our crew in the plant works with this compound on a regular basis, watching its fine behavior during synthesis, its interaction with other reactants, and, finally, its application in industry. This isn’t a commodity gas or a generic fluorocarbon; it’s a material born for researchers who know what precision really means.

    What Sets Our Product Apart

    When you handle 1-Bromo-2-Iodotetrafluoroethane, you realize its performance stems from the careful selection of starting materials and attention to detail throughout the process. The substance offers a well-defined tetrafluoroethane core, but with bromine and iodine bringing specialized reactivity. This changes the game for labs and technologists pursuing organofluorine experimentation or crafting advanced building blocks in pharma, agro, and electronics.

    Unlike a straight-chain fluorocarbon, the bromine and iodine handle a wider range of reactivity under practical working conditions. We have learned that the presence of both halogens produces a stable yet highly versatile compound. As a group, we have observed our customers driving syntheses that traditional fluorocarbons or mono-halogenated compounds can't achieve. By controlling every step from halogen exchange to purification, we've driven impurity levels to a minimum, providing consistency batch after batch.

    Specifications That Matter to Chemists

    Purity isn’t simply a number on a sheet; it’s how you avoid wasted time and uncertain outcomes at the lab bench. Tried and tested protocols support this product’s purity profile, and we keep contaminants—especially related dihalides, water, and acid residues—away from the final bottles. We don’t just test these parameters during quality control; we design the entire process from the first feedstock to respect the sensitivity of halogenated organics.

    Physical qualities deserve real-world attention too. Our refrigeration controls prevent decomposition, and dedicated glassware preserves color and avoids catalytic contamination. Each batch is labeled for transparency. Over years, we’ve trained our production staff to recognize even small deviations in appearance or odor—even before analytical reports confirm the result.

    Handling and Storage—From Our Experience

    Anyone who works with highly halogenated organics knows they call for respect, not just a line in the safety manual. Our team values hands-on protocols like double-checking seals and keeping inert gas flowing during transfer. We build our plant procedures on decades of feedback—stories from technicians who remember a leaky valve, or a bottle left just a little too warm.

    A tightly sealed amber glass or fluoropolymer container prevents light and air from creeping in. Staff maintain cold chain integrity during packing, and distributors appreciate that we avoid plastic tubing, which can cause slow but real loss through permeation or catalytic degradation. Over the years, fewer handling incidents and consistent product shelf life have repaid this careful work.

    Applications Driven by Real Outcomes

    Our direct conversations with synthetic chemists inform us that 1-Bromo-2-Iodotetrafluoroethane has earned a niche, especially where a high-energy leaving group or site-selective fluorination unlocks new molecular frameworks. University researchers report successes attaching this moiety to aromatic or unsaturated compounds, where neither non-halogenated tetrafluoroethane nor single-halogen variants would react or control side products.

    Other test labs appreciate its function as a starting material for more complex fluorinated and halogenated compounds. In pharma development, our material enables late-stage functionalization—chemists know the risks of switching to a less selective or dirtier halide source. Over the years, we’ve heard good reports about improved reliability in coupling reactions, where minimal impurity load from our product boosts yield consistency.

    In electronics manufacturing, especially for specialty etchants or intermediates in advanced materials, reliability counts for more than just price per gram. Our material shows stable volatility and avoids contamination that could disrupt sensitive deposition or doping steps. Every year, feedback from customers shapes our improvements in handling, bottling, and technical support.

    Why We Focus on Ingredient Sourcing and Production Control

    Our process starts with high-quality, traceable raw materials. What goes in at the start determines what comes out at the finish. Using cheap halogen sources creates more than just yield losses—it means inconsistent purity and unpredictable side reactions, which nobody needs in even a modest research project.

    We make sure to source each reagent from trusted suppliers. Staff confirm documentation before every receipt, and samples get tested before loading. Each run gets a unique lot number, letting us track every batch through to the finished product, so if any client ever has a question, we can pinpoint every production and test variable that went into that drum or bottle.

    Differences from Industry-Standard Halocarbons

    Comparing 1-Bromo-2-Iodotetrafluoroethane to other similar molecules is straightforward only on paper. In the plant, it’s a different animal. The combined presence of bromine and iodine shifts boiling points, refractive indices, and even the vapor pressure in ways that single-halogen or lighter analogs can’t match. Our team spends time tuning distillation columns, watching for telltale inflections in boiling behavior or solubility.

    Our trials with other halocarbons, like chloro- or bromo-tetrafluoroethanes, reveal less selectivity in downstream derivatization. Chemists often struggle with single-halogen materials, running into unexpected side reactions or an inability to introduce multiple new functional groups at controlled sites. The heavier iodine atom in our compound gives the right combination of reactivity and stability that projects demand in medicinal chemistry and advanced materials.

    We don’t treat all halogenated gases or liquids as interchangeable. When making halogenated arenes or perfluorinated sidechains, predictability comes only from using the right starting material. Customer feedback often tells us that switching to our dual-halogen version knocks down development costs and slashes wasted time hunting down causes of yield loss or contamination.

    On Purity, Testing, and Transparency

    Lab results and certificates only go as far as the care that goes into the process. Every bottle carries more than a label; it carries hundreds of hours of oversight from synthesis through to final inspection. We routinely use high-field NMR, gas chromatography, and trace halogen analysis for each produced lot. By engaging third-party labs for parallel confirmation, we strengthen both our confidence and that of our customers relying on precise chemical behavior in demanding syntheses.

    If a hiccup occurs and some anomaly crops up in quality testing, we pull the entire lot, dig into root causes, and never release questionable material. By refusing to relax standards during times of tight supply or labor shortages, we have earned the trust of clients doing high-stakes work. We openly publish variance reports and compile annual technical performance digests for our users.

    Feedback Drives Continual Improvement

    Chemists reach out to us when something doesn't meet expectation, or when a batch delivers higher than average results. We don’t see these calls as complaints but as guidance. We return every communication with technical explanations, not platitudes or dodges. Real people on our team answer tough questions about trace metals, halide migration, or unusual odor profiles, and we integrate those insights into process improvements month after month.

    For instance, a few years ago repeated feedback on microcontaminant build-up, seen during advanced coupling reactions, had us overhaul filtration stages and shift to a cleaner, more inert process setup. Results came quickly—eye-opening reductions in unexpected by-products, with measurable increases in reaction yield for multiple customer applications.

    Technical Support from Direct Experience

    Our chemists and plant engineers serve as technical contacts because they’ve been on the line, not because they’ve memorized a list of FAQs. When a scientist calls with a challenge—say, a stubborn reaction stalling despite pure conditions—we walk through variables, troubleshooting from firsthand experience with the same compound. Sometimes it’s a temperature tweak, sometimes a different solvent pairing, or a new addition sequence.

    Users appreciate a supplier who doesn’t just quote literature values. Instead, our people swap experimental details, discuss impurity traces, or even help set up trial runs in remote collaboration. We know the difference a few parts per million of impurity can make in a sensitive synthesis, and we don’t dismiss subtle anomalies as lab artifacts. This genuine, back-and-forth support culture has blocked countless failed experiments and prevented weeks of wasted R&D effort.

    Sustainability and Responsible Manufacturing

    Handling halogenated organics and fluorochemicals brings a heavy responsibility. Our plant implements strict containment and fume handling systems, eliminating uncontrolled emissions and recycling as much process stream as feasible. Our crew participates actively in safety audits and community outreach, acknowledging that specialty chemical production can draw concern from neighbors and regulators.

    Where the chemistry allows, we retrofit equipment for lower energy use and have adopted safer alternatives for legacy reagents. Even when industry standards don’t require a specific containment or monitoring protocol, we institute controls that reflect the real risks of halogen volatilization or corrosive by-product formation. We track and report emissions to local authorities, accepting external audits and publicizing results.

    Disposal routines follow best-in-class directions. We neutralize waste on site, never sending untreated halogenated residues into municipal waste channels, and provide customers with honest, actionable guidance on minimizing their own downstream impact. This commitment matters to our staff, who live in the same communities as the factories.

    Industry Trends and Market Perspective

    The growing complexity of pharmaceutical and materials research drives a hunger for reliable, specialized reagents. Every year, we see more requests from groups looking to functionalize novel scaffolds, seeking halogenated fluorocarbons with greater control over reaction kinetics. While simple halocarbons once ruled, dual-halogen and hybrid structures like 1-Bromo-2-Iodotetrafluoroethane now dominate the high-value margin where repeatability trumps cost-per-unit.

    We track changes in demand, watching for shifts in synthesis strategies—like the migration away from environmentally risky solvents, or the move to lower-pressure systems. Our technical team keeps close contact with clients in cutting-edge universities and startups, learning which features they find most valuable and which pain points keep cropping up across the sector.

    Raw material accessibility also changes, and we adjust supply plans based on fluctuations in global bromine and iodine markets, hedging procurement to stave off cost shocks for our customers. This strategic view lets us guarantee long-term supply, minimizing disruptions that can cripple time-sensitive projects in demanding areas like drug development or electronics prototyping.

    Connections to Research and Commercial Practice

    The true measure of success doesn’t lie in a purity certificate or a full warehouse; it comes from seeing a customer break through roadblocks using your material. We cherish each story where a new compound, pathway, or device draws life from a batch manufactured on our line. University and corporate partners have taken our product well beyond standard applications into ambitious programs—developing therapies, protective coatings, or semiconductor prototypes—and continue to teach us what matters most.

    After years listening to client breakthroughs and frustrations, we understand that speed, transparency, and reliability set resilient partnerships. The difference between a smooth scale-up and a failed grant can be a single shipment, or a fast answer to a late-night email. By closing the distance between production and end use, we have seen greater loyalty, honest feedback, and technical progress stand tall in a market thick with intermediaries and rebranders.

    Openness and Learning in Specialty Chemical Production

    Technology moves faster than standards, and yesterday’s exotic intermediate is today’s workhorse. By fostering real conversations between plant staff, bench chemists, and product developers, we improve not just a molecule, but the whole value chain serving research and industry. We do not treat clients simply as end points for a product; we treat them as scientific partners whose insight sharpens our process and whose discoveries push us to upgrade standards and adapt to unforeseen needs.

    By maintaining an open channel from shop floor to laboratory, emerging trends and process improvements get shared quickly. Successful collaborations raise the bar for everyone using 1-Bromo-2-Iodotetrafluoroethane: setting expectations higher for purity, traceability, technical backup, and safe, sustainable sourcing. In all these areas, day-to-day know-how from actual production experience counts for more than rote documentation, and our culture reflects that truth.