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1-Benzyl-2-Methyl-1H-Imidazole

    • Product Name 1-Benzyl-2-Methyl-1H-Imidazole
    • Alias 1-Benzyl-2-methylimidazole
    • Einecs 694-980-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    558082

    Chemical Name 1-Benzyl-2-Methyl-1H-Imidazole
    Molecular Formula C11H12N2
    Molecular Weight 172.23 g/mol
    Cas Number 22945-12-8
    Appearance White to off-white solid
    Melting Point 53-56°C
    Boiling Point 314°C at 760 mmHg
    Density 1.09 g/cm3
    Solubility In Water Slightly soluble
    Flash Point 143°C
    Purity Typically >98%
    Smiles Cc1nccn1Cc2ccccc2

    As an accredited 1-Benzyl-2-Methyl-1H-Imidazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 grams of 1-Benzyl-2-Methyl-1H-Imidazole; labeled with hazard warnings and chemical identification.
    Shipping 1-Benzyl-2-Methyl-1H-Imidazole is shipped in tightly sealed containers, compliant with chemical transport regulations. It should be protected from moisture, heat, and direct sunlight. The package is clearly labeled with hazard information and handled by authorized personnel. Shipping documentation includes safety data sheets and emergency procedures, ensuring secure and regulated delivery.
    Storage Store **1-Benzyl-2-methyl-1H-imidazole** in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers and acids. Protect from moisture and direct sunlight. Ensure proper labeling, and keep away from food and drink. Use personal protective equipment when handling to avoid skin and eye contact.
    Application of 1-Benzyl-2-Methyl-1H-Imidazole

    Applications of 1-Benzyl-2-Methyl-1H-Imidazole in Industrial Manufacturing

    As a direct manufacturer, we supply 1-Benzyl-2-Methyl-1H-Imidazole for critical roles in targeted chemical value chains. Below, we detail its downstream applications, compliance benchmarks, working ratios, and process integration points for real industrial customers.

    1. Pharmaceutical Intermediate for Antifungal Active Ingredients

    Pharmaceutical producers utilize this compound as a building block in the synthesis of selective antifungal actives, especially triazole derivatives. It takes part in nucleophilic substitution and cyclization steps to impart the desired imidazole functionality critical for bioactivity. Its molecular profile allows for precise control of reactivity and finished product purity during the API synthesis stage.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP, ICH Q7)
    • United States Pharmacopeia (USP) API intermediate guidelines
    • European Pharmacopoeia (Ph. Eur.) quality standards
    • REACH Regulation (EC) No 1907/2006 for registration and handling

    Typical usage ratio

    • Batch-to-batch, 1.2 to 1.8 molar equivalents to substrate depending on synthetic route and target yield of API

    Downstream process integration

    • Charged in first-stage condensation or ring closure during intermediate manufacturing
    • Reacted with various halogenated or acylated intermediates
    • Incorporated in multi-step synthesis after in-process QC for purity and identity
    • Subjected to final purification, followed by downstream granulation or crystallization before API isolation

    Final product types

    • Econazole nitrate (antifungal API)
    • Miconazole and related triazole class APIs
    • Pharmaceutical intermediates for custom synthesis projects
    • Research-grade imidazole antifungal standards

    2. Curing Accelerator for Epoxy Resin Systems

    Epoxy system manufacturers and composite formulators employ this imidazole derivative as a reactive curing accelerator. Its electronic properties accelerate epoxy ring-opening and promote advanced crosslink density, especially in high-performance coatings, adhesives, and electrical potting compounds. Process engineers value its low volatility and compatibility in solventless formulations.

    Industry compliance standards

    • ISO 9001:2015 certified quality management
    • Restriction of Hazardous Substances (RoHS) compliance for electronics
    • UL 94 flame retardancy (where electrical insulation is required)
    • REACH registered for industrial polymer processing

    Typical usage ratio

    • 0.2% to 1.5% by weight based on total epoxy resin mass—selection depends on hardener type, gel time targets, and final mechanical requirements

    Downstream process integration

    • Introduced into resin mix after base and modifier blending
    • Dispersed under high shear before addition of hardeners or additives
    • Utilized in factory-scale blending vessels, monitored via gel time and DSC analysis
    • Mixed immediately before casting, winding, or coating operations

    Final product types

    • High voltage electrical encapsulants
    • Structural adhesives for composites
    • Industrial floor coatings
    • Fiber-reinforced laminates

    3. Ligand Precursor in Homogeneous Catalyst Manufacture

    Catalyst producers apply this compound as a ligand precursor to synthesize N-heterocyclic carbene (NHC) complexes, which serve as highly selective homogeneous catalysts in fine chemical and pharmaceutical manufacturing. The imidazole scaffold enables formation of metal-organic architectures with customized activity and solubility profiles, facilitating reactions such as cross-coupling and hydrogenation.

    Industry compliance standards

    • ISO 9001:2015 quality systems for catalyst production
    • REACH compliance for all catalyst intermediates
    • SHEQ (Safety, Health, Environment, Quality) procedures for handling nitrogen heterocycles
    • Documentation traceability per ICH Q11 guidelines for pharmaceutical catalysts

    Typical usage ratio

    • Stoichiometric or sub-stoichiometric (0.8–1.1 molar equivalents) versus metal precursor, adjustable relative to ligand exchange efficiency

    Downstream process integration

    • Reacted with metal chlorides or salts in inert atmosphere reactors
    • Deprotonation and complexation steps controlled at low temperatures for selectivity
    • Purified by crystallization or chromatography prior to catalyst formulation
    • Final catalyst standardized for assay and solubility prior to shipment

    Final product types

    • Organometallic catalysts for pharmaceutical synthesis
    • Palladium or ruthenium NHC complexes for cross-coupling
    • Olefin metathesis catalysts
    • Chiral ligands for enantioselective synthesis

    4. Additive for Corrosion-Inhibiting Coatings

    Industrial coating manufacturers integrate this imidazole as a specialty additive for waterborne and solvent-based anticorrosion systems. It acts via film-forming and coordination mechanisms with metal surfaces, improving resistance properties on ferrous substrates. The compound demonstrates thermal and chemical stability, making it suitable for long-life protection in challenging environments.

    Industry compliance standards

    • ISO 12944:2018 (Corrosion protection by protective paint systems)
    • ASTM D7091 for dry film thickness
    • REACH Annex XVII for safe additive usage
    • Local environmental VOC directives for paint manufacturing

    Typical usage ratio

    • 0.5%–2.5% by weight in dry film; dosage adjusted based on coating type and targeted salt spray test hours

    Downstream process integration

    • Added during pre-mix phase alongside dispersing agents
    • Dissolved into base binder system with other performance additives
    • Shear-mixed to ensure homogeneity
    • Evaluated in accelerated corrosion test panels before scale-up

    Final product types

    • Industrial maintenance primers and topcoats
    • Pipeline and tank lining systems
    • Automotive underbody coatings
    • Marine protective paints

    5. Chemical Intermediate for Specialty Agrochemical Synthesis

    Producers of active ingredients for crop protection employ this molecule as a core intermediate in synthesizing selective fungicides and seed treatment chemicals. It supports structural modification of imidazole rings and incorporation into bioactive heterocycles, providing effective molecular scaffolds for new agro formulations.

    Industry compliance standards

    • FAO/WHO Joint Meeting on Pesticide Specifications (JMPS)
    • EU Regulation (EC) 1107/2009 on plant protection products
    • OECD guidelines for chemical testing (metabolite evaluation)
    • ISO 17025:2017 laboratory QC methods

    Typical usage ratio

    • 1.0 to 1.5 molar equivalents relative to halogenated or acylated intermediates; reactivity optimized for maximum conversion rate

    Downstream process integration

    • Employed in controlled batch reactions during active ingredient synthesis steps
    • Subject to chromatographic or distillative purification
    • QC-checked for residual imidazole and related impurities
    • Transferred to formulation for blending into solid or liquid dispersions

    Final product types

    • Seed treatment fungicides based on imidazole chemistry
    • Agrochemical technical grade intermediates
    • Chemical building blocks for new generation pesticides
    • Synthons for research agrochemical candidates

    6. Research Reagent in Advanced Materials Synthesis

    R&D centers and advanced materials labs apply this imidazole derivative as a synthesis reagent and template for constructing novel metal-organic frameworks (MOFs), supramolecular assemblies, and conducting polymers. Its chemical structure enables selective interaction with transition metals, influencing pore size, conductivity, or optical behavior in new materials.

    Industry compliance standards

    • ISO 17034:2016 for certified reference material production where applicable
    • Standard materials safety and handling under ISO 45001:2018
    • GHS (Globally Harmonized System) classification for MSDS provision
    • REACH registration for laboratory supply chain

    Typical usage ratio

    • Varies by target structure: 0.5–2.0 molar equivalents per metal atom in MOF synthesis; tailored via experimental design

    Downstream process integration

    • Used in precursor solution during hydrothermal or solvothermal synthesis
    • Combined with metal salts and other linkers in autoclave or reactor vessels
    • Controlled heating and pH adjustment for material crystallization
    • Downstream activation, drying, or functionalization for target properties

    Final product types

    • Gas storage or separation MOFs
    • Electrochemical sensor materials
    • Advanced battery electrode substances
    • Prototype functional polymers for electronics or photonics
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    Certification & Compliance
    More Introduction

    1-Benzyl-2-Methyl-1H-Imidazole: A Closer Look from a Manufacturer's Perspective

    Real Results in Imidazole Chemistry

    Clients in the pharmaceutical, agrochemical, and specialty chemical segments look for consistent quality and reliable performance from 1-Benzyl-2-Methyl-1H-Imidazole. Direct experience in scaling production and supporting new applications has taught us this molecule can open the door to applications requiring both selectivity and manageable reactivity. In advanced synthesis and as an intermediate, the structure of 1-Benzyl-2-Methyl-1H-Imidazole provides both rigidity and modification options. True value in this field comes from rigorous attention to batch integrity and real-world feedback from partners who develop new routes and final products based on reliable building blocks.

    Specifications and Usability Shape Outcomes

    The technical team ensures product meets high purity standards with well-controlled impurity profiles. Years of investment and development let us confidently supply 1-Benzyl-2-Methyl-1H-Imidazole in white to pale yellow crystalline form, commonly at 99% minimum purity. Water content and trace contaminants get monitored batch-by-batch to support customers calibrating analytical methods or upscaling production. Supply chain is more than moving drums; we guarantee tight specification, repeatable physical properties, and responsive technical support from start to finish.

    Clients with pilot or commercial manufacturing needs trust us to maintain analytical transparency, covering melting point, infrared spectrum, and assay details. Our teams actively refine isolation steps to reduce solvent residues, and finished product is tested for shelf stability under typical storage conditions. Direct batch feedback confirms both laboratory and plant-scale chemistries react predictably, even at higher concentrations or with more demanding reaction partners. Those developing next-generation treatments or catalysts often rely on the consistency of our specification controls.

    Differentiators in a Dynamic Market

    Many products in the imidazole category look similar on paper, and a surprising number arrive in the same forms globally. The distinction with genuine manufacturer supply comes down to process know-how and technical backstopping behind every lot. Investing in reactor control systems and real-time analytics keeps specifications tight and results reproducible at any scale, not just for small samples. From raw materials to final packaging, every step reflects a control philosophy based on minimizing cross-element contamination and maximizing traceability. Direct manufacturing oversight means our product profile grows with client needs, not market guesswork.

    Compared to 1-methyl or unsubstituted imidazoles, the benzyl and methyl substitutions each materially influence both electronic properties and downstream chemistry. 1-Benzyl-2-Methyl-1H-Imidazole resists side reactions under certain basic or oxidizing conditions where simpler imidazoles falter. For example, in heterocyclization sequences, the added bulk of the benzyl group supports regioselective formation of target compounds with reduced by-product risk. Medicinal chemists seeking specificity in functionalization also note improved yields from the methyl substitution at the two-position. Performance data gathered at scale supports the selection of this analog over similar compounds where product flexibility and handling safety rank as project priorities.

    Real-World Uses Define Product Value

    Most 1-Benzyl-2-Methyl-1H-Imidazole flows into intermediates for active pharmaceutical ingredients and high-value agrochemicals. Based on hands-on technical exchange, researchers and scale-up managers reach for this compound because it builds advanced heterocycles with fewer purification burdens than some alternative scaffolds. Projects involving antifungal, antiviral, or CNS candidate molecules benefit from more predictable routes that avoid unnecessary downstream complications. Synthesis teams work more efficiently with a product that maintains integrity even after weeks in storage or repeated temperature cycles during transport.

    Research teams pointed out secondary uses in ligand design for transition metal catalysis and for synthesis of specialty resins where the imidazole ring influences curing kinetics or charge mobility. Formulators engaged in niche electronic applications have adopted the product based on its balance of solubility and chemical stability. Industry moves fast, and manufacturers who understand both the old and new applications make the difference when clients have scale-up questions or an unexpected challenge. This experience lets us suggest alternate purification or isolation methods if a customer requires material for applications outside traditional pharma or ag.

    Supply-Chain Assurance Stems from Direct Process Control

    Supplying a specialty heterocycle like 1-Benzyl-2-Methyl-1H-Imidazole involves disciplined sourcing of starting materials and fine-tuned isolation protocols. Regular maintenance and process review drive both yield and batch-to-batch stability. Decision to standardize on glass-lined vessel interiors traced back to reducing trace metal contamination, which affects not only spectroscopic clarity but also end-user reaction reliability. Strict procedural compliance, not just for regulatory comfort but for downstream partner trust, remains at the heart of the manufacturing operation. These process and quality refinements show themselves in real-world end-use case studies, from improved catalyst lifetimes to better biological screening results in R&D pipelines.

    With every order, our technical and logistics teams monitor transit conditions, investigate client feedback, and adjust in-process documentation according to both new and legacy customer needs. Feedback loops extend beyond basic Certificates of Analysis: real suppliers respond to concerns on process throughput, recovery rates, or unexpected color changes spotted in trial batches. Incremental improvements in filtration, drying, and packing minimize process dust and maximize usable yield for the next stage of use. Supply teams bring feedback back into production strategy, directly closing the loop between factory and research bench.

    Knowledge and Consistency Overcome Commodity Pitfalls

    At the practical level, the distinction between a consistent production facility and the open market grows sharper each year. Sourcing 1-Benzyl-2-Methyl-1H-Imidazole from unverified brokers exposes projects to risk—ranging from inconsistent impurity levels to batch delays and cost surprises. We have seen the after-effects of material supplied from fragmented routes: off-color product, unexplained coordination interference in catalytic cycles, and sometimes stalled development timelines due to impurity headaches. Direct manufacturer supply, anchored by decades of process expertise and technical repeatability, offers more than documentable traceability—it means new product requests and special grade runs get real technical attention with the actual process decision-makers.

    Analytical support extends to new impurity standards or repackaging studies when clients raise bespoke needs. Our investment in additional analytical methods, like high-sensitivity LC-MS for trace-level detection or DSC scans for polymorph orientation, means informed advice on real-life technical problems. Questions that crop up during regulatory filing or method validation do not linger—our staff can access detailed batch histories, raw data sets, and process development notes without external delays.

    Supporting Advanced Chemistry, Not Just Moving Barrels

    Shifting from research scale to pilot, then to full production creates fresh challenges every step. Our long-term view focuses on supporting these transitions with actionable guidance, whether on solvent compatibility, in-process modifications, or scaled-up workup recommendations. Attention to data—on everything from trace by-products to real-world dissolutions—saves time and prevents costly surprises in late-stage development. Close proximity between plant teams and technical liaison staff lets us troubleshoot issues in real time, skipping days of back-and-forth loop with distant broker networks.

    Long-standing relationships with repeat customers shape our priorities year after year. Feedback from medicinal chemists pushed us to refine washing steps and implement enhanced spectroscopic screening for residual aromatics; electronics formulators influenced decisions on physical handling and shipment controls. This collaborative approach means a new project gets real-world advice and support, not a generic product reference. Clients take on challenging new syntheses with greater confidence when their raw material offers both purity and responsive technical backing.

    No Substitute for Primary Expertise

    Manufacturers work with more than order numbers—we manage challenges, solve probems, and learn from process upsets just as end users do. 1-Benzyl-2-Methyl-1H-Imidazole presents technical challenges in scale-up, particularly in solvent selection and thermal management. Our process engineers mapped out thermal profiles to minimize side products and invested in energy-efficient cooling systems to keep stepwise exotherms under control. Earlier experience detecting packaging incompatibilities led us to refine the anti-static lining on drums. A supplier without manufacturing roots misses these insights; batch consistency and recoverable yield depend on learning from near-misses and actual production noise every week.

    Continued investment in process development has allowed us to expand capacity and finesse purification steps without amplifying cost. We keep meticulous logs of both process variables and in-process analytics. This practice allowed us to scale up quickly for special orders while supporting legacy clients with the same high standards applied to first batches out of the plant. The team engages directly in industry best practice forums and knowledge exchanges, further refining product and process through both formal and informal data sharing.

    Traceable Quality, Responsive Improvement

    Focusing on product stewardship, we maintain clear chain-of-custody on all batches, validated by third-party audits as well as ongoing in-house checks. Every input and every step are recorded and reviewable. Rapid-response technical support is available for post-delivery application questions, with detailed impurity profiles and secondary reference standards available for high-sensitivity research efforts. Over the years, requests for custom particle sizes or even customized stabilization agents led to documented production changes, always validated first in the plant before rolling out to customers.

    Peer review, regular audit, and collaborative trouble-shooting routines allow us to learn and improve—no theoretical workflow, but grounded in daily plant life. Miniaturized analytical screens speed up batch release and align with evolving regulatory expectations. Technical and QA teams meet after every batch run to talk through deviations and flag opportunities that would escape notice in paper-only, broker-led models. These focused, constant improvements mean customers receive reliable raw material that directly reduces risk in their most critical projects.

    Market Feedback Drives Innovation

    Developers working on new pharmaceuticals need not only product reliability, but clarity about process robustness and possible future specification tightening. We incorporate this market insight into every run, tracking potential process bottlenecks and experimenting with advanced solvents or greener conditions where possible. Ongoing dialogue helps us adapt to new regulatory expectations, whether related to environmental sustainability, waste minimization, or trace impurity management. Our recent efforts to shrink solvent use in downstream workups and invest in closed-loop cleaning systems show a direct response to both feedback and evolving market standards.

    We listen and adapt. Clients asked for new container sizes and eco-friendly shipment, so we expanded returnable container options and continue to explore biobased packaging where possible. Real-world product use and feedback have contributed directly to these advances. Operating as a true manufacturer, not a broker or paper trader, gives us the flexibility to respond quickly and the responsibility to own every outcome.

    Conclusion: Building on Real-World Experience

    Years of manufacturing 1-Benzyl-2-Methyl-1H-Imidazole have shown that expertise, not just documentation, separates quality chemical suppliers from the rest. Controlling both process and product, we can stand behind every shipment and every lot with both process data and technical experience. From early development to commercial launch, consistent supply and technical partnership drive better outcomes for chemists, scale-up managers, and QA teams in the industries we supply. Continued focus on traceability, responsiveness, and practical improvement means our 1-Benzyl-2-Methyl-1H-Imidazole matches the demands of today’s most innovative projects.