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1-Benzoyl-3-Phenyl-2-Thiourea

    • Product Name 1-Benzoyl-3-Phenyl-2-Thiourea
    • Alias 1-Benzoyl-3-phenyl-2-thiourea
    • Einecs 229-387-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    560222

    Chemical Name 1-Benzoyl-3-Phenyl-2-Thiourea
    Molecular Formula C14H12N2OS
    Molecular Weight 256.33 g/mol
    Cas Number 5326-28-1
    Appearance White to off-white crystalline powder
    Melting Point 168-172°C
    Solubility Slightly soluble in water; soluble in ethanol, acetone, chloroform
    Boiling Point Decomposes before boiling
    Density 1.295 g/cm³ (estimated)
    Storage Temperature Store at room temperature, dry conditions
    Purity Typically ≥98%
    Iupac Name 1-benzoyl-3-phenylthiourea

    As an accredited 1-Benzoyl-3-Phenyl-2-Thiourea factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, tightly-sealed amber glass bottle containing 100g of 1-Benzoyl-3-Phenyl-2-Thiourea, labeled with hazard, chemical, and manufacturer details.
    Shipping 1-Benzoyl-3-Phenyl-2-Thiourea should be shipped in a tightly sealed container, away from light, moisture, and incompatible substances. It must be handled according to relevant chemical shipping regulations, labeled appropriately, and transported at ambient temperature. Ensure safe packaging to prevent leaks or breakage during transit, complying with all applicable safety guidelines.
    Storage **1-Benzoyl-3-Phenyl-2-Thiourea** should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from moisture, heat, and incompatible materials such as strong oxidizing agents. Protect it from light and direct sunlight. Label the container clearly, and keep it away from food and drink to prevent accidental ingestion or contamination.
    Application of 1-Benzoyl-3-Phenyl-2-Thiourea

    Applications of 1-Benzoyl-3-Phenyl-2-Thiourea in Industrial Manufacturing

    We supply high-purity 1-Benzoyl-3-Phenyl-2-Thiourea directly to global industrial clients for use in specialized downstream segments. Its application depends on precise compliance with industry-specific quality standards, and our technical support team provides guidance from raw material selection to formulation and production integration in diverse sectors.

    1. Ore Flotation Reagent for Non-Ferrous Metal Mining

    Mining operations deploy this thiourea derivative as a selective collector in flotation circuits for ore beneficiation, especially in the recovery of precious and base metals such as copper, gold, silver, and complex sulfide ores. The compound’s high selectivity and surface interaction properties enable targeting specific minerals under controlled pH and reagent conditions, enhancing concentrate yield and purity while meeting process safety and regulatory requirements. Customers adjust dosing based on ore composition and operational targets to remain within permitted environmental discharge limits.

    Industry compliance standards

    • ISO 12743 (Sampling of copper, lead, zinc and nickel concentrates)
    • Hazardous Substances regulations (REACH Regulation (EC) No 1907/2006-Europe)
    • Environmental Protection Standards for Mining (US EPA - Effluent Guidelines for Ore Mining and Dressing - 40 CFR Part 440)
    • Occupational exposure and handling under OSHA 29 CFR 1910

    Typical usage ratio

    • 0.02–0.10 kg per metric ton of ore, adjusted based on ore sulfide content, gangue mineralogy, and water chemistry

    Downstream process integration

    • Direct addition to flotation cell slurry after initial grinding and conditioning step
    • Precise metering through reagent dosing pumps incorporated in automated control loops

    Final product types

    • Flotation copper concentrate
    • Gold and silver concentrate
    • Lead-zinc bulk concentrates

    2. Intermediate for Pharmaceutical Synthesis

    Pharmaceutical manufacturers incorporate this specialty thiourea derivative at key stages of API synthesis, especially in the preparation of thiosemicarbazone-based drugs and selective kinase inhibitors. The compound supports regioselective transformations and heterocycle formation under cGMP-controlled environments. Its high assay and controlled impurity levels make it suitable for regulated markets, with strict batch traceability and documentation for regulatory review.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients
    • 21 CFR Part 210/211 (US FDA cGMP requirements)
    • EU GMP Directive 2003/94/EC
    • Relevant local pharmacopeias (USP, EP, JP as applicable in end markets)

    Typical usage ratio

    • 0.5–5 mol% relative to substrate in key synthetic steps, dictated by reaction specificity and required product purity

    Downstream process integration

    • Charged as starting reagent or intermediate in closed reactor systems at heterocycle condensation and cyclization stages
    • All steps under validated process protocols with in-process analytical QC (HPLC, GC-MS)

    Final product types

    • Thiosemicarbazone APIs
    • Specialty oncology kinase inhibitors
    • Research-grade heterocyclic drug intermediates

    3. Vulcanization Accelerator for Rubber Processing

    Rubber processors select this aromatic thiourea class agent as a non-nitrosamine vulcanization accelerator in the production of technical, automotive, and industrial rubber goods. It supports rapid crosslinking with sulfur at precise activation temperatures, improving mechanical strength and aging resistance in tires, belts, and conveyor products. Its selection often aims to lower total secondary amine generation and facilitate compliance with consumer product safety directives.

    Industry compliance standards

    • ISO 9001 Quality Management Systems during compounding and production
    • REACH Registration and SVHC disclosure (EC/1907/2006)
    • Automotive OEM material specifications (ISO/TS 16949 for automotive supply)
    • RoHS Directive (2015/863/EU) for use in electrical/electronic rubber parts

    Typical usage ratio

    • 0.3–1.2 phr (parts per hundred rubber) as co-accelerator, tuned according to crosslink density and final product performance benchmarks

    Downstream process integration

    • Dry blending into masterbatch during initial mixing on Banbury or open mill
    • Thorough dispersion before final calendering, extrusion, or molding under controlled temperature

    Final product types

    • Automotive tires
    • Industrial conveyor belts
    • Technical molded rubber components

    4. Crystal Growth Modifier for Specialty Pigments

    Pigment manufacturers employ this thiourea reagent as a crystal growth habit modifier during the aqueous precipitation of high-performance pigments, such as diketopyrrolopyrrole (DPP) and certain phthalocyanine classes. Its presence assists in refining particle morphology, hue purity, and dispersion, reducing downstream milling loss and ensuring compliance with color strength tolerances required for high-end coatings and plastics applications.

    Industry compliance standards

    • EN 71-3 European Toy Safety Standard for pigment materials (for end use in toys/coatings)
    • ISO 787/26 (General methods of test for pigments and extenders - Determination of pH value of aqueous suspension)
    • REACH compliance for pigment components
    • BfR Recommendation IX (Colorants for Plastics - German Federal Institute for Risk Assessment)

    Typical usage ratio

    • 0.02–0.08% by weight of pigment batch, optimized for particle size, chroma, and filterability by batch colorimetric analysis

    Downstream process integration

    • Meticulously added as an aqueous solution at nucleation or crystal growth stage during pigment precipitation
    • Subsequent washing and drying of modified pigment particles; performance QC follows DIN ISO standards

    Final product types

    • High-performance DPP pigments
    • Phthalocyanine green/blue pigments
    • Color masterbatches for engineering resins

    5. Corrosion Inhibitor in Steel Pickling and Acid Cleaning

    Integrated steel and metal finishing plants add this compound as an acid pickling corrosion inhibitor to protect ferrous substrates from excessive metal loss and hydrogen embrittlement during hydrochloric or sulfuric acid cleaning. Its surface-active properties adsorb onto steel, reducing dissolution rates and extending bath life. Dosage optimization must address steel alloy, bath acid strength, and temperature to maintain consistent performance within regulated discharge limits.

    Industry compliance standards

    • ISO 8044:2020 (Corrosion of metals and alloys - Basic terms and definitions)
    • REACH (EC 1907/2006) for chemical substances in metal surface treatment
    • ASTM A380/A380M (Cleaning, descaling, and passivation of stainless steel parts)
    • Relevant local wastewater and environmental discharge regulations (e.g., US EPA NPDES)

    Typical usage ratio

    • 0.01–0.08% by volume of pickling acid solution, adjusted in line with steel type, scale thickness, and bath turnover rate

    Downstream process integration

    • Continuous dosing through acid recirculation line upstream of pickling tanks
    • Performance monitoring via corrosion coupon analysis and solution titration

    Final product types

    • Pickled steel coils and sheets
    • Bright steel wire
    • Precision acid-cleaned steel pipes
    Free Quote

    Competitive 1-Benzoyl-3-Phenyl-2-Thiourea prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Tel: +8615371019725

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    Certification & Compliance
    More Introduction

    Introducing 1-Benzoyl-3-Phenyl-2-Thiourea: Purpose-Built Performance from Our Production Line

    Turning Raw Materials Into Reliable Solutions

    We’ve guided 1-Benzoyl-3-phenyl-2-thiourea through every stage of its existence, from sourcing the first kilo of raw material to quality checks on the finished batch. Every synthesis run in our facilities showcases the real value behind direct manufacturing: unprecedented control, traceability, and the knowledge that every lot reflects what our chemists have learned over years of hands-on production. Whenever a new order is prepared, our team reviews current conditions—moisture, temperature, even the purity of the starting benzanilide. Production means owning the responsibility for consistency, so our staff run HPLC and melting point checks on each lot, documenting trends and improvements over time, not just shipping numbers off a spec sheet. Every slab, every crystal that leaves our site carries the story of these decisions.

    We’ve maintained the same fundamental synthetic pathway for this compound since first introducing it to our product line. We source benzanilide and phenylisothiocyanate from partners we vet personally, relying on high-yield reactions that limit unwanted byproducts. Our technical staff have studied the kinetics and thermodynamics of this route in depth to minimize side reactions, using batch and semi-batch reactors depending on order size. Acetonitrile sometimes provides better selectivity at scale than ethanol under certain temperatures, so our shift supervisor keeps detailed records on solvent choice, stirring speed, and cooling profiles. As procedures shift slightly for each run, records pile up in well-worn logbooks, helping younger chemists build on successes and learn from rare setbacks. Manufacturing 1-benzoyl-3-phenyl-2-thiourea isn’t about batch numbers; it’s about improvement and reliability, not just running the next vessel.

    Specifications Shaped by Day-to-Day Production

    Real-world manufacturing specs don’t come from a catalog—they develop after years on the floor, routine analysis, and back-and-forth with clients. Most of our product leaves the plant as a white to light tan crystalline powder, but color can shift slightly with upstream solvent differences or batch cooling rates. Our specification puts purity above 99 percent by HPLC, but we know trace impurities and residual solvents matter for downstream applications, so we regularly report on even faint signals in our spectra. Moisture control starts in the drying phase; every drum is vacuum-dried and nitrogen-flushed before sealing.

    Granule size influences solubility in customer processes, so we offer regular product after sieving through 100-mesh, but several key clients require a specific fraction for optimal stir-in performance, and our team grinds and sieves to order. Bulk density, flow characteristics, and compaction are measured per shipment with each run logged to catch deviations early—and if a trend arises, process engineers review their protocols instead of brushing it off as a shipping problem. All these details reflect our hands-on approach; specifications change only after we’ve verified that production shifts actually give our clients better control.

    Applications From Hands-On Experience, Not Just Hearsay

    We’ve spent years building relationships with clients in the pharmaceutical, agrochemical, and specialty intermediates sectors. Early on, we sold only a small quantity each month, mainly for R&D teams exploring new synthetic routes. As demand built from formulation groups and custom synthesis houses, our own process feedback improved. R&D chemists regularly test new derivatives in our pilot lab and share results that inform our own customers about what works—not from marketing, but from the actual boots-on-the-ground results.

    Pharmaceutical companies rely on the stability and reactivity of 1-benzoyl-3-phenyl-2-thiourea for building blocks in heterocyclic chemistry, especially where rigid scaffold structures or sulfur incorporation matter. Our product runs through several solid-phase synthetic processes for library construction. Our technical team regularly discusses solubility and crystallization properties with formulators who use it as a reagent in the preparation of certain nitrogens and as an acylation partner. We often provide samples matched by specific lot number for trial batches, allowing clients to test changes without risking production failures down the line.

    Some crop science customers select 1-benzoyl-3-phenyl-2-thiourea not for biological activity itself, but for its function as a synthetic handle—offering a tunable combination of donor and acceptor sites that supports more complex ligand frameworks. Several production runs have been tailored to provide very low metal ion content, after researchers at an academic group published improved yields with these grades. Our ability to shift process controls to match research needs helps drive scale-up projects, saving customers steps in downstream purification because of up-front process discipline.

    Clients active in the dye and pigment sector report that the structural features of the molecule promote strong chromophore coupling and compatibility with sulfidic or carbonyl-rich intermediates. A color-formulation specialist once requested tighter sulfur content specifications for a new azo dye, and our lab team responded with batch-by-batch sulfur analysis to deliver what off-the-shelf intermediates could not. Long-term, these experiences shape how we monitor our own product and adapt both our documentation and our analytical approach.

    What Makes Our Product Different: Lessons Learned, Results Delivered

    True difference comes from knowing every step between raw inputs and customer hands. Our material is not repackaged or relabeled at any stage—every container, drum, and sample comes straight from our line with a batch number that ties back to a full production record. We don’t depend on external QA or merchant stock; our in-house analytical lab runs FTIR, NMR, and purity cross-checks every week. Any deviation, whether a melting point anomaly or solubility complaint, brings the production team together to dig for answers before the next order.

    Compared to third-party, multi-vendor sources, our consistency shows up in fewer batch-to-batch surprises and fewer calls about insoluble residues. We hold all product for a full seven days of stability testing under varying moisture and temperature before release—even rush orders don’t skip this phase. Shipment lots come with both certificate of analysis and detailed processing notes by default; customers often notice that our COAs reflect the scale and date of actual production, not just a standard compound entry.

    While traders and resellers may focus on the lowest price or fastest turnaround, end users in pharma, agro, and materials research tell us that downtime from variable quality costs more than any savings on paper. Clients regularly cross-check our shipment results over months or even years and often send back positive feedback highlighting not just the product—1-benzoyl-3-phenyl-2-thiourea itself—but the process transparency that comes from dealing direct with a manufacturer who stands behind every batch.

    Challenges We Face and How We Respond

    Bleeding-edge science keeps moving. Customer demands rarely match each other or stay fixed for long. Several years ago, new European chemical safety regulations changed the acceptability threshold for one minor residual, requiring our team to redesign a post-reaction workup and add an extra evaporation step. This spurred a round of investment in drying and vent recapture equipment, not only meeting compliance but further reducing odor and dust in our shipping area. We invite audit teams from customer and regulatory groups to tour our line, verify lot segregation, and trace finished goods to source. Engineers spend late nights when new impurity signals turn up, and operators have the standing instruction to halt any shipment until they confirm root cause and corrective action.

    A pressing issue surfaced when a major customer started noting minor variance in melting point. Our technical team traced the source to a minor change in the supply chain of acetonitrile, which altered the solvent evaporation rate and, in turn, the crystal habit of the final compound. We responded not by hiding or ignoring the reports, but by engaging customers with direct updates, adjusting solvent suppliers, then running side-by-side crystallizations for comparison. After three cycles, melting point drift returned to historic norms, and our most technical clients applauded the transparency and follow-through. Experiences like this only reinforce our view that manufacturing means showing your work, not just quoting targets.

    Not all challenges stem from within the plant. Unexpected shifts in global logistics, from shipping delays to new packaging standards, impact every order. During a recent supply crunch for packaging materials, our logistics staff reached out directly to core customers, explaining new drum suppliers, updated lot seals, and shipping times face-to-face rather than hiding behind email updates. This kind of directness, learned through years in the industry, supports the trust that keeps long-term customers returning for our product.

    Meanwhile, sustainability expectations keep climbing. Downstream firms want traceable, low-waste sources. As a manufacturer, we review solvent recycling metrics and byproduct minimization annually, updating our mechanical and chemical process steps to cut waste at the source. Waste solvent capture from each run now supplies our in-house cleaning operations, and filter waste heads to specialized processors. Environmental monitoring plays as much a part in our daily routines as production metrics—the two walk hand-in-hand in the modern factory.

    Supporting Customer Success Through Dialogue and Adaptation

    We see each inquiry about our product as a two-way conversation, not a one-time handoff. New applications, analysis requests, and technical queries arrive weekly, sometimes offbeat and sometimes illuminating. Our customer support staff work directly with production chemists and analysts, relaying sample requests, reporting on batch characteristics, or sharing feedback about how small tweaks in our process make a difference in the field.

    Some clients have begun pushing the limits of impurity control, asking for tighter sulfur or nitrogen analysis. Others have flagged issues with trace metals for their chromatographic or synthetic routes. In response, our team rolled out routine ICP-MS and Karl Fischer titrations, sharing results openly and integrating these findings into our release workflow—not as an occasional favor, but as the new baseline. Every time a new question arises, it prompts process review. For us, real improvement comes not from generic specs, but from being open to scrutiny, quick to respond, and willing to tweak processes to fit live feedback.

    Nobody in the plant is just “compliance staff” or a faceless QA tech. Our team takes pride in knowing how customer methods interact with our process choices, whether it’s pre-drying glassware, adjusting addition rates, or reviewing solvent lots yet again. Every new question about downstream use becomes part of our feedback chain, shaping the next production run and sometimes even changing the way we document intermediate steps. The rhythm in the production hall reflects this mindset: improvement driven both by science and by the real-world needs of every chemist or engineer relying on our material.

    Trust Built on Real-World Experience

    Our history manufacturing 1-benzoyl-3-phenyl-2-thiourea means we own not just the product, but its evolution. As knowledge has deepened, so has our capability to provide something distinct: not just material, but ongoing support, adaptations, and transparency. The relationships we’ve built with formulators and process chemists shape our daily choices, from tightening specs to accommodating a novel application in a late-stage R&D project. Feedback cycles that started a decade ago still echo through our plant floor, ensuring technical concerns never get smoothed over in the name of expedience.

    Whenever a new use is uncovered or a process changes on the customer side, our staff want to know how it impacts their work. If a specialty chemicals group calls for a novel filtration profile, we don’t just adjust, we test and report, keeping an open line back to the field. In this way, every new requirement or concern becomes both a challenge and an opportunity for improvement—a philosophy born not from the sales desk but from the shop floor, analytical lab, and years spent refining every batch.

    Manufacturing direct means taking ownership through every pound produced, every certificate documented, and every customer question answered with data and experience. The upshot: the reliability of 1-benzoyl-3-phenyl-2-thiourea isn’t an accident of circumstance or luck in raw material sourcing. It’s the direct result of a team committed to learning, acting, and adapting for the benefit of those who depend on their product. Our journey continues as new challenges arise and customers look for solutions we haven’t imagined yet—each batch reminding us that trust and traceability grow with every good decision made.