Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

1,6-Heptadien-4-ol

    • Product Name 1,6-Heptadien-4-ol
    • Alias 4-Hepten-1-ol
    • Einecs 242-045-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    499631

    Cas Number 928-92-3
    Iupac Name hepta-1,6-dien-4-ol
    Molecular Formula C7H12O
    Molar Mass 112.17 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 160-162°C
    Density 0.87 g/cm³
    Flash Point 49°C (closed cup)
    Solubility In Water Slightly soluble
    Refractive Index 1.448 - 1.452
    Smiles C=CCC(O)CC=C
    Inchi InChI=1S/C7H12O/c1-3-5-7(8)6-4-2/h3-4,7-8H,1-2,5-6H2
    Pubchem Cid 135853

    As an accredited 1,6-Heptadien-4-ol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 100 mL, tightly sealed with screw cap, labeled with chemical name, purity, hazard symbols, and handling instructions.
    Shipping **Shipping Description for 1,6-Heptadien-4-ol:** 1,6-Heptadien-4-ol should be shipped in tightly sealed containers, protected from light, heat, and moisture. Use appropriate hazardous material labeling as required. Transport according to all relevant local, national, and international regulations, ensuring compatibility with other substances and secure containment to prevent leaks or spills during transit.
    Storage 1,6-Heptadien-4-ol should be stored in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and properly labeled. Store separately from strong oxidizing agents, acids, and bases. Use appropriate chemical-resistant containers to prevent leaks or degradation, and avoid moisture intrusion to ensure product stability and safety.
    Application of 1,6-Heptadien-4-ol

    Applications of 1,6-Heptadien-4-ol in Industrial Manufacturing

    As a direct manufacturer specializing in the development and scale-up of unsaturated alcohol intermediates, we supply 1,6-Heptadien-4-ol to a range of advanced industrial sectors. Below, we outline its primary application scenarios based on our end-user base, technical audits, and verified customer production processes.

    1. Specialty Polymerization Monomer for Crosslinked Polymer Networks

    Producers of specialty crosslinked copolymers incorporate 1,6-Heptadien-4-ol as a multi-vinyl functional monomer, leveraging its diene positions for advanced network formation and its hydroxyl group for chemical modification or further crosslinking. This monomer plays a role in controlling mechanical properties, solvent resistance, and flexibility of the resulting materials, especially in castable and molded engineering plastics and elastomers. Engineers adjust loading levels to regulate crosslink density and tailor the polymer’s end-use performance. The addition usually occurs during the pre-polymer batch stage under nitrogen, prior to the major chain-growth polymerization or radical initiation.

    Industry compliance standards

    • REACH Annex XVII and SVHC clearance for monomers used in Europe
    • ISO 9001:2015 certified polymer production
    • RoHS (Restriction of Hazardous Substances) for electronics-facing plastics
    • GB/T 24186 (China) for high-performance elastomeric polymers

    Typical usage ratio

    • 0.5%–5% w/w based on total monomer charge; partners may adjust according to targeted crosslink density and flexibility requirements.

    Downstream process integration

    • Added during monomer premix stage, prior to initiator dosing and polymerization.
    • Can be post-modified after partial polymerization to graft side-chain functionalities.

    Final product types

    • UV-curable crosslinked coatings
    • Flexible polyurethane elastomers
    • Electronics-grade encapsulating resins
    • Chemically resistant pipes and seals

    2. Intermediate for Fine Fragrance and Flavor Ingredient Synthesis

    Industrial fragrance and flavor houses use 1,6-Heptadien-4-ol as a key intermediate in the multi-step synthesis of aliphatic alcohols, musks, and structurally complex aroma compounds. Its diene functionality provides a scaffold for Diels-Alder reactions, cyclizations, and selective hydrogenation, while the alcohol group enables subsequent esterification or etherification steps. Each reaction step faces tight quality control over trace byproducts and residual solvents to comply with global regulatory requirements for food-grade and cosmetic applications.

    Industry compliance standards

    • IFRA Standards for fragrance components
    • FDA 21 CFR 172.515 for flavoring substances (United States)
    • EU Regulation (EC) No 1334/2008 for flavoring substances
    • ISO 22716:2007 for cosmetic ingredient manufacturing

    Typical usage ratio

    • Used as a key scaffold in stoichiometric amounts; precise charge level determined by targeted batch output and downstream conversion efficiency (typically 1 molar equivalent when acting as a main building block).

    Downstream process integration

    • Introduced as a starting reagent in the aromatic synthesis sequence, typically in a controlled batch reactor under inert atmosphere.
    • Undergoes hydrogenation, cyclization, or functional group transformation steps before final purification.

    Final product types

    • Aliphatic musk base ingredients
    • Macrocyclic lactone aroma chemicals
    • Specialty fine chemicals for fragrance accords
    • Natural-identical food flavoring agents

    3. Precursor for Pharmaceutical Intermediate Synthesis

    API and pharmaceutical intermediate manufacturers employ 1,6-Heptadien-4-ol for constructing chiral scaffolds and chain-extended side groups in the development of small molecule drugs and advanced intermediates. The dual unsaturated structure enables conjugate addition and selective functionalization, often via controlled hydroboration-oxidation or asymmetric dihydroxylation reactions, providing access to intermediate structures for further amination or cyclization. Strict compliance with traceability, solvate control, and production documentation is maintained throughout the multi-step synthetic sequence.

    Industry compliance standards

    • ICH Q7 GMP Guide for active pharmaceutical ingredients
    • USP–NF monograph for intermediate quality verification
    • EDQM CEP processes for export to European markets
    • China NMPA (CFDA) Drug Master File (DMF) system

    Typical usage ratio

    • Varies 1–2 molar equivalents per synthetic route step; exact amount specified by process R&D based on target molecule design.

    Downstream process integration

    • Introduced at the initial alkylation or side chain formation stage in API intermediate synthesis.
    • Subsequent purification steps handled under GMP conditions to ensure batch consistency.

    Final product types

    • Advanced pharmaceutical intermediates for antihypertensive APIs
    • Chiral amine building blocks for CNS drugs
    • Side-chain modified active intermediates for oncology research

    4. Modifier for Functional Silanes and Silicone Materials

    Manufacturers in the silicone and organosilane segment incorporate 1,6-Heptadien-4-ol as a reactive unsaturated alcohol for the synthesis of specialized silane coupling agents and flexible silicone crosslinkers. Through hydrosilylation or hydroalkoxysilylation, the diene segments attach to Si-H or Si-alkoxy sites, generating functionalized silanes that improve adhesion, hydrophobicity, or compatibility with organic resins. Careful control of the addition sequence, catalyst loadings, and conversion endpoints optimizes the silane functionality and the performance in downstream sealants or adhesives.

    Industry compliance standards

    • ASTM D3935 for silicone resin additives
    • ISO 9001:2015 for specialty chemical manufacturing
    • GB/T 20106 for construction-grade silane/siloxane materials
    • UL 94 testing for end-use in flame-retardant sealants

    Typical usage ratio

    • 1–10% w/w based on total silane or silicone precursor charge, adjusted to match targeted silane functionalization and final polymer network characteristics.

    Downstream process integration

    • Added during silane synthesis after initial hydrolysis or before end-group capping stages.
    • Integrated into silicone masterbatch blending for advanced adhesive formulations.

    Final product types

    • Adhesion-promoting silane modifiers for construction sealants
    • Flexible RTV (room temperature vulcanizing) silicone rubbers
    • Water-repellent coatings for electronics
    • Reactive silicone-based adhesive systems

    5. Starting Material for Agrochemical Synthesis

    In agrochemical manufacturing, technical grade 1,6-Heptadien-4-ol acts as a starting material for the design of new synthetic herbicide and pesticide scaffolds, especially for those requiring unsaturated alcohol fragments as side chains or for cyclization into active heterocycles. The material’s dual double bonds and alcohol group allow efficient transformation into reactive intermediates, which downstream plants convert into active ingredients. Production requires tight control over raw material traceability, residue levels, and batch environmental documentation due to export regulations and end-market safety assessments.

    Industry compliance standards

    • FAO/WHO Technical Guidelines for pesticide manufacturing
    • OECD Good Laboratory Practice (GLP) for residue trials
    • ISO 14001:2015 for environmental management in fine chemical synthesis
    • US EPA 40 CFR Part 158 for pesticide registration support

    Typical usage ratio

    • 0.5–3 molar equivalents, depending on synthetic route and yield targets for the specific agrochemical active ingredient.

    Downstream process integration

    • Charged as primary alcohol component in early stage of multi-step synthesis.
    • Processed through subsequent cyclization, alkylation, or selective oxidation steps to form heterocyclic or side chain-substituted APIs.

    Final product types

    • Heterocyclic herbicide intermediates
    • Pesticide actives with unsaturated side chains
    • Precursor compounds for seed treatment agents
    Free Quote

    Competitive 1,6-Heptadien-4-ol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Getting to Know 1,6-Heptadien-4-ol: A Perspective from the Manufacturer

    Introduction: Working with 1,6-Heptadien-4-ol in Real Chemical Production

    Every day in the manufacturing plant, choices about which raw materials to run through the reactors shape far more than just one batch. One of the unsung yet crucial compounds on our work floor is 1,6-Heptadien-4-ol. This molecule may not generate a lot of headlines, but anyone in synthesis, especially around specialty chemicals and intermediates, knows the advantage of a stable supply paired with reliable quality.

    1,6-Heptadien-4-ol slots into production runs for both R&D specialists and scale-up teams. Here, we see the requests come in from those driving new molecule discovery as well as from teams optimizing pathways for commercial production. Unlike many commodity alcohols, this compound’s unique two terminal double bonds coupled with a central alcohol function open doors in synthesis that saturated alternatives just can’t.

    Chemical Makeup and Why That Matters in Our Daily Production

    The molecule itself carries two reactive C=C double bonds at either end of its seven-carbon chain. We prepare it with a hydroxyl group at the fourth carbon. Technically, the IUPAC name—hepta-1,6-diene-4-ol—signals both reactivity and a route for downstream functionalization. In our synthesis department, this means we’re working with a compound that supports allylation or cross-coupling, plus more tailored reactions linking two chemical spaces through the alcohol moiety.

    Every batch run relies on strict process control. Typical manufacturing purity hovers at 98% or above, with GC data supporting the real-world usage of each lot. From the viewpoint of the people running the columns and reactors, keeping isomeric byproducts in check is not just about quality on paper—it keeps downstream teams from wrestling with purification headaches.

    Actual Factory Usage: Learning What 1,6-Heptadien-4-ol Can Do

    Daily requests from our partners in pharmaceutical, agrochemical, and polymer fields often point to three practical uses for 1,6-Heptadien-4-ol. For pharmaceutical intermediates, our customers blend it into multi-step syntheses targeting ring-closing metathesis or other cyclization reactions. It doesn’t get lost in the shuffle; those dual alkene handles mean chemists can create macrocycles and spiro-compounds that saturated alcohols won’t yield.

    Polymer researchers approach us for its role in specialty formulation, especially in UV-curable resins and cross-linkable materials. Having two double bonds to work with in one molecule leads to higher cross-link density and a different property profile compared to using mono-olefinic or saturated alcohols. In photochemistry, that structure allows for inventive oligomer design without importing extra functional groups from outside the main backbone.

    In agrochemical pathways, process ChemEs see mileage in the straightforward conversion of the alcohol into ethers, esters, or various coupling products—always with the advantage of diallyl-type reactivity. Anyone with experience bench-scales and reactors appreciates the practical benefit here: going from raw starting material to a versatile intermediate in fewer steps saves time, labor, and waste.

    What Sets 1,6-Heptadien-4-ol Apart From Other Alcohols

    After years in this industry, you learn that not all C7 alcohols merit a place on the regular order sheet. What gives 1,6-Heptadien-4-ol its edge is the functional freedom from its unsaturation pattern. Contrast this with simple heptanol or its saturated cousins, and you see their chemistry stops short in olefination, metathesis, and cyclization contexts.

    1,3-Heptadien-5-ol and 1,7-heptadiene lack the balanced central group needed for symmetric addition or ring closure without side-product issues. The symmetrical diene spacing in 1,6-heptadien-4-ol gives process chemists a tool to build linkers and scaffolds for more advanced synthetic targets. Over time, process teams have reported back to us fewer problems with byproduct formation in cross-coupling runs compared to other dienic alcohols.

    It’s worth noting the performance difference in UV-curable applications too. Other alcohols—even those with single alkene groups—tend to restrict the cross-linking density and curing speed, so product performance lags. Running 1,6-heptadien-4-ol down the line, we routinely see stronger polymer networks and improved mechanical properties. These aren’t figures plucked from marketing copy—they come from our QC department, running everything from FT-IR to mechanical tests.

    Knowing the Downstream Needs: Challenges Our Customers Face

    Fielding feedback is a constant reality in manufacturing. Teams scaling up for the first time often report a need for tighter control over moisture or trace isomer content in our 1,6-heptadien-4-ol. If production let those slip, it’d gum up their catalysis or downstream coupling steps. Our facility responded by integrating a final dehydration and polishing stage in the process, sacrificing some throughput but winning stability for our customers’ high-stakes syntheses.

    Another real-world complication is logistics. Not every site can handle bulk shipping of high-purity, highly reactive alcohols. Our experience prompted us to overhaul packaging—switching to inert-gas-filled containers and lining internals to stop unintended polymerization during long shipments. Reports from clients confirmed: That small process tweak helped them avoid costly, time-consuming rework because oxidative spoilage dropped off their radar.

    Safety Experience Driving Our Production Philosophy

    Walking through the plant, the aroma of unsaturated alcohol is hard to ignore, especially with 1,6-heptadien-4-ol as it wafts from drums after blending. Manufacturing staff emphasize consistent ventilation setups and rapid transfer lines for this compound; that’s not just about ticking boxes—it’s experience talking. Early handling trials flagged that high surface-area spills could polymerize or oxidize in open air, especially in warm, humid conditions.

    By prioritizing operator training and treating process safety data as job-critical, we keep our uptime high and recordable incidents low. Experience taught us to use pressure-tested drums with vented lids along with on-site nitrogen blanketing. New process operators spend time shadowing veterans before they run transfer pumps solo. This isn’t glamourous, but it reflects real lessons learned.

    Commitment to Quality and Real-World Testing

    Supplying to research and scale-up plants keeps us sharp. Our lot-release routine for 1,6-heptadien-4-ol relies on not just analytical purity (GC, NMR, and Karl Fischer for water content) but test reactions. One regular quality check prepares a standard ether from our material and sends a sample through alkene metathesis. Only pure product, free from problematic side-reactions, passes along to the warehouse.

    Feedback from synthetic labs and pilot plants has shaped our batch release guidelines. A few years ago, materials flagged as “high purity” by analytics still performed poorly in a polycondensation trial at a specialty polymer plant. Taking that experience, we now test a sample from each lot in actual syntheses using customer-reported conditions. If a hiccup pops up in catalysis or polymerization, we troubleshoot before it ships, not after.

    Sourcing and Traceability Built from Experience

    Colleagues at the purchasing desk juggle more than just price and delivery date for 1,6-heptadien-4-ol. Raw precursor quality, traceability of supply chain, and certificates of analysis get regular scrutiny. Over the years, supply chain disruptions forced us to source alternate precursors, and we saw first-hand how trace contaminants affect finished product quality. Since then, we’ve locked in secondary suppliers and mapped their QC processes before using any new raw material in production.

    On traceability, our team stamps every shipment with batch and test data matched to archived retention samples. Unexpected questions from customer QA teams can then be answered fast. We don’t simply trust that paperwork equals performance—real plant experience led us to offer lot-level tracking, and in a recall event, fast documentation is the only thing standing between a straightforward fix and a prolonged headache for all involved.

    Environmental Responsibility as Part of Operations

    Many days, decisions about solvent usage and waste streams feel burdensome, but overlooking them adds risk. We redefined our solvent recovery for 1,6-heptadien-4-ol production cycles after internal audits pointed out avoidable waste in distillation columns. Using closed-loop distillation, we cut solvent consumption and lowered atmospheric VOC emissions as verified by our emissions monitoring program.

    We had to revamp water management as well. Mid-process washing and final product feeds go through in-house purification before recycling, which slashed fresh water use at our facility. Regulatory audits prompted us to add secondary containment in the raw material offloading areas, reducing the risk of environmental releases. These steps didn’t appear overnight; implementing them meant pausing production for weeks at a time and investing in new infrastructure.

    Some clients demand eco-profile data on our 1,6-heptadien-4-ol. Instead of canned answers, we share our emissions tracking reports and third-party audits. This transparency equips our customers to respond to their regulatory and sustainability questions with data that reflects actual plant operations, not just hopes.

    Collaborating with Customers: Problem Solving on the Factory Floor

    Support for customers buying 1,6-heptadien-4-ol rarely stops at shipping a drum. Technical service staff work alongside their R&D or process chemists to adapt reaction conditions for best results. One common issue we tackled in the field involved an early lot that failed to deliver expected polymerization results under exposure to UV light. The problem traced back to stabilizer content, which didn’t fit their process window. Our team reformulated, retested, and teamed up on the plant floor until the process stabilized—turnaround grounded in real process chemistry, not just advice from a distance.

    Another situation called for modifying impurity cutoffs. A specialty pharma client flagged trace halogen byproducts that drifted above new regulatory limits. We made process changes to swap out the original halogenated solvent, validated the new route, and locked in the updated specs with fresh certificates of analysis. That kind of agility only becomes possible when manufacturing and QC teams talk with the chemists who actually run the downstream reactions.

    The conversations also run toward packaging. For startups or university groups experimenting with 1,6-heptadien-4-ol, there’s less interest in bulk drums and more in lab-friendly bottles. Plant scheduling accommodates this by running small-batch bottling and ensuring even 1 kg bottles pass full lot inspection. This sort of flexibility traces back to early years, when we ourselves scrambled for access to hard-to-source intermediates in manageable sizes.

    Technical Specifications: What Real Users Should Expect

    Each specification sheet leaves room for improvement based on years of trial and error. In actual practice, we keep water content below 0.5%, alkene impurities below 1%, and total organic byproducts as detected by HPLC no higher than 1.5%. Color, measured by Hazen, rarely crests above 15 in finished product. We learned through joint troubleshooting with clients that even trace levels of certain impurities can alter catalyst response or create off-odors in finished resins.

    Our own R&D staff employ the same standard materials in their synthesis work, so real-world feedback cycles directly into quality control. If a batch falls outside customer-validated parameters, it never leaves the QC bay. Decades of experience with 1,6-heptadien-4-ol and related specialty alcohols convinced us that technical performance on paper needs to be proven in the customer’s process, not just in the lab or by the numbers.

    Shipping, Storage, and Handling: Lessons Learned in Avoiding Waste and Hazards

    Drummed stock of 1,6-heptadien-4-ol wants cool, dark, and dry spots. Experience in our own warehouse and at downstream partner facilities taught us that high heat or sunlight risks runaway reactions, polymerization, and off-odors. Each drum runs with an inert nitrogen blanket, stoppers rated for chemical compatibility, and an outer label warning of the risks tied to high reactivity. We use fully vented containers for air shipments after one summer transport led to unexpected drum pressurization.

    Even small lapses during transfer or blending can cause measurable quality drift. Our operators employ sealed line systems with regular purges and cleaning between runs. Routine checks on equipment ensure that everyone from warehouse staff to final users can track every drum and bottle by serial lot.

    Customers running scale-up often need tech support around safe transfer methods—one team reported sticky residues after attempting open-air additions. Our solution came from sharing our own closed drum-pump system and onsite demonstration, which solved their issue and became their in-house SOP.

    Looking Toward Process Improvement with 1,6-Heptadien-4-ol

    Change is constant in specialty chemical supply. Over the years, customer feedback has pushed us toward continuous process upgrades. For 1,6-heptadien-4-ol, energy savings, yield, and byproduct minimization now guide batch-to-batch adjustments. Inline process analytics replaced once-a-day sampling, and automated shutdowns cut response times on any parameter drift. We benchmark improvements not just by internal cost, but by the cleaner, more reliable product seen by those running the next steps of their process.

    Process improvements don’t happen in a vacuum. When new applications for 1,6-heptadien-4-ol pop up—from cross-linked networks in functional materials to next-generation pharmaceutical linkers—our process engineers adapt purification and QC to fit the new requirements. In many regions, shifting regulatory standards on impurities or handling drive us toward lower limits and new process validations.

    Summary: The Value of Experience-Driven Manufacturing

    Years spent making, packaging, and supporting 1,6-heptadien-4-ol has shaped how we see specialty chemical supply. Quality matters, but so does listening to those who actually run the chemistry and knowing how small plant-floor choices ripple through the supply chain. Each drum, bottle, or bulk shipment reflects more than compliance—it carries the learning built up from solving real challenges alongside our customers.

    Running a saponification, building up a polymer backbone, or closing a ring in a pharmaceutical synthesis means relying on intermediates that arrive as promised. That forms not just the backbone of good chemistry, but ongoing trust between manufacturer and user. As applications develop, our team stands ready to adapt, problem-solve, and keep reliability at the forefront for every order delivered.