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1,6-Dibromoperfluorohexane

    • Product Name 1,6-Dibromoperfluorohexane
    • Alias Perfluorohexane dibromide
    • Einecs 221-273-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    705733

    Product Name 1,6-Dibromoperfluorohexane
    Chemical Formula C6Br2F10
    Cas Number 355-46-4
    Appearance Colorless liquid
    Boiling Point 155-157 °C
    Melting Point -33 °C
    Density 2.234 g/cm3
    Refractive Index 1.355
    Flash Point Non-flammable
    Solubility In Water Insoluble

    As an accredited 1,6-Dibromoperfluorohexane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,6-Dibromoperfluorohexane is packaged in a 100-gram amber glass bottle with a secure screw cap, labeled for chemical safety.
    Shipping 1,6-Dibromoperfluorohexane is typically shipped in sealed, chemical-resistant containers to prevent leaks and contamination. It should be handled as a hazardous material, following regulations for transport of organic bromides. Proper labeling and documentation are required, and the shipment must be protected from heat, physical damage, and incompatible substances during transit.
    Storage 1,6-Dibromoperfluorohexane should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong bases and oxidizing agents. Keep it away from sources of ignition and protect from moisture. Store at room temperature and avoid exposure to direct sunlight. Use secondary containment to prevent leaks or spills, following all applicable safety regulations.
    Application of 1,6-Dibromoperfluorohexane

    Applications of 1,6-Dibromoperfluorohexane in Industrial Manufacturing

    1,6-Dibromoperfluorohexane plays a key role in highly controlled chemical syntheses and advanced polymer manufacturing. Its unique molecular structure and reactivity underpin several critical processes in the fine chemicals and specialty materials industries. Below are main downstream application fields, with precise production standards, integration data, and finished product details as practiced by industry factories.

    1. Fluorinated Surfactant Synthesis for Firefighting Foams

    Our material serves as a major intermediate for building C6-based fluorosurfactants, replacing legacy C8/PFOA routes in firefighting foam formulations. It introduces both perfluoroalkyl and brominated functionalities, supporting the synthesis of modern AFFF agents with improved environmental profiles. Industrial formulators exploit its reactivity for chain extension and introduce functional groups, optimizing surface tension reduction while maintaining compliance with the latest regulatory guidance on PFAS emissions.

    Industry compliance standards

    • OECD PFAS Guideline (PFAS Analytical Standardization, 2019)
    • US EPA 40 CFR Part 721 (Significant New Use Rules – PFAS compounds)
    • EN 1568-3 European Fire Protection Standard (Foam Concentrates Performance)
    • ISO 9001:2015 (Quality Systems for production traceability and process control)

    Typical usage ratio

    • As a building block: 10-45% of total reactor charge, adjusted for C6 or C4 co-monomer content
    • Ratio optimization follows terminal group preference and target HLB value

    Downstream process integration

    • Introduced during the telomerization or alkylation step as a semi-bulk reagent
    • Acts as a chain transfer agent in the fluoroalkyl synthesis module
    • Subjected to bromine exchange or nucleophilic substitution under mild base conditions

    Final product types

    • C6-based AFFF firefighting foam concentrates
    • Fluorinated surfactant intermediates for industrial and aviation foam
    • PFAS-free wetting agents (under REACH-compliant limits)

    2. Monomer Precursor in Fluoropolymer Manufacturing

    As a key intermediate in the production of specialty fluoropolymers, 1,6-dibromoperfluorohexane enables the synthesis of high-molecular-weight resins. Manufacturers use it for functionalizing copolymers with precise chain length and crosslinking density. This monomer enters direct copolymerization or substitution, imparting high chemical resistance and controlled flexibility—a requirement for wire & cable jacketing, specialty gaskets, and fuel-resistant elastomers.

    Industry compliance standards

    • ASTM D2116 (Standard Specification for FEP—Fluorinated Ethylene Propylene Resin)
    • ISO 14001 (Process Environmental Management controlled for fluoropolymer plants)
    • EN 60332-1-2 (Halogen-free polymer fire resistance for cable applications)

    Typical usage ratio

    • 1-7% by weight of monomer feedstock during block or random copolymerization
    • Adjusted according to required polymer chain flexibility and final application area

    Downstream process integration

    • Fed during pre-polymerization or crosslinking stage in continuous or batch reactors
    • Participates in fluoroalkylation, followed by in situ dehalogenation or functional terminal group attachment
    • Enables formation of telechelic polymers via stepwise synthesis

    Final product types

    • High-performance fluoropolymer resins for extrusion
    • Heat-shrinkable tubing for aerospace and electronics
    • Chemical-resistant wire insulation materials
    • Fuel system sealing rings and PTFE-modified elastomers

    3. Specialty Chemical Intermediate for Pharmaceutical Fluorination

    Pharmaceutical CDMOs and API manufacturers use this compound as a controlled fluorinated segment source for assembling complex molecules. 1,6-Dibromoperfluorohexane provides selectivity in nucleophilic substitution and aromatic alkylation, introducing perfluoroalkyl chains into pharmaceutical building blocks where metabolic stability and hydrophobicity are essential. All process steps must comply with international pharmacopeia monographs and traceability requirements.

    Industry compliance standards

    • ICH Q7 and ICH Q11 (Good Manufacturing Practice for APIs and intermediates)
    • USP/NF Compendial standards for fluorinated building blocks
    • European Pharmacopoeia 10.0 (Synthesis and impurity control)

    Typical usage ratio

    • 0.1-2.5 molar equivalents in alkylation or fluorination reactions, typically as a limiting reagent
    • Adjusted to step selectivity and minimization of halogenated by-products

    Downstream process integration

    • Added during the late-stage functionalization of API intermediates
    • Used in batch reactors with full GMP documentation and impurity tracking
    • Involved in etherification or aryl substitution steps for fluorocarbon chain placement

    Final product types

    • Perfluoroalkylated pharmaceutical intermediates and active ingredients
    • Drug candidates requiring improved metabolic and chemical resistance
    • Complex small molecules for oncology and metabolic disease pipelines

    4. Precursor for Fluorinated Performance Coatings

    Coating formulators deploy 1,6-dibromoperfluorohexane in the synthesis of advanced surface protection systems, particularly for electronics and optics. Its reactivity enables end-capping or grafting of perfluoroalkyl groups onto siloxanes, acrylics, or other resin systems. This approach yields coatings with extreme water and oil repellency, serving sectors that demand minimal surface energy and reliable anti-fouling properties.

    Industry compliance standards

    • RoHS Directive 2011/65/EU (Restrictions of certain hazardous substances in electronics)
    • ISO 4618 (Paints and varnishes—Terms and definitions, for process and QC references)
    • REACH Annex XVII (PFAS and halogenated substance registration and tracking)

    Typical usage ratio

    • 3-15% by weight in the resin blend, based on surface energy optimization and durability requirements
    • Adjusted by target hydrophobicity and specific resin compatibility

    Downstream process integration

    • Incorporated at pre-polymer blend stage or during post-reaction graft modification
    • Participates in thermal or UV-induced curing processes to anchor fluorinated segments
    • Monitored for residual bromine to meet finished goods purity targets

    Final product types

    • Anti-stain electronics coatings for smartphones, tablets, and display panels
    • Hydrophobic and oleophobic barrier layers for optical lenses
    • Advanced architectural surface protectors for glass and metal facades
    Free Quote

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    Certification & Compliance
    More Introduction

    1,6-Dibromoperfluorohexane: A Closer Look from a Manufacturer’s Bench

    Understanding the Substance: What Sets 1,6-Dibromoperfluorohexane Apart

    Every batch of 1,6-Dibromoperfluorohexane rolling out of our plant carries with it a quiet legacy of precision and attention to detail. Over decades working with perfluorinated intermediates, we’ve learned a lot about why this specific molecule turns heads among chemists and engineers. With a formula of C6Br2F12, this perfluoroalkyl bromide stands out for its unique combination of chemical stability, reactivity at the terminal bromine atoms, and a robust backbone resistant to harsh reaction conditions. Unlike shorter-chained analogues, such as 1,4-Dibromoperfluorobutane, the six-carbon chain imparts a perfect balance between flexibility and reactivity, creating wider windows for planning syntheses and scaling up reactions.

    Over the years, the consistency of our production—measured not simply in purity but in lot-to-lot reproducibility—has proven vital to industrial customers. Achieving this requires rigorous attention on the shop floor. Automated distillation columns, real-time NMR checks, and an insistence on freshly handled feedstock have been our standard. This isn’t just about numbers on a specification sheet; in fluorine chemistry, minute impurities can unravel an entire downstream process. With 1,6-Dibromoperfluorohexane, every kilo represents years of ironing out bottlenecks at the interface where organic synthesis meets scale-up equipment and environmental stewardship.

    Production Nuances: Why It Matters How 1,6-Dibromoperfluorohexane Is Made

    Producing perfluorinated dibromides is a tricky business. Early on, raw materials taught us respect for high-boiling fluorocarbons, as even trace metallic contamination or substandard bromine led to side-products that gummed up both purification columns and end-use performance. We learned to keep all contact surfaces free of reactive residues and to dedicate glass-lined reactors just to this class of chemicals. Even a small drift in bromination reaction temperature shifted product profiles. We keep a detailed eye on process control: the exotherm spike midway through bromination, the subtle change in column pressure during vacuum distillation, and the tight time window before over-bromination starts creating by-products.

    Cross-contamination remains a real concern. We taught ourselves hard lessons during years we tried toggling synthesis between different perfluoroalkyl chains in the same system. Today, complete shutdown and high-temperature cleaning precede any switch to another product. Here, experience trumps any written protocol. On a practical level, these habits add up: our 1,6-Dibromoperfluorohexane emerges clear, with no trace color, and passes the most stringent GC-MS checklists—something most customers only appreciate after they struggle with residues on their own end or discover volatility shifts in products coming from less meticulous plants.

    Product Characteristics: More Than Just Purity

    On the page, 1,6-Dibromoperfluorohexane seems another in a long line of perfluorinated chemicals. In real-world use, differences become clear fast. The bromine atoms at both ends bring a unique reactivity, launching this molecule into applications that pure perfluoroalkanes cannot touch. The six-carbon perfluoro backbone imparts not just resistance to acids, bases, and oxidizers, but also an unreactive core that allows selective chemistry at the terminal positions. Think about building up a specialty monomer or surfactant: reactions can be tuned to swap out the bromines for different functional groups, opening doors to advanced applications.

    We’ve watched our material succeed where others stall, such as when customers need long-term thermal stability in harsh process environments. The robust C6F12 core resists both high temperatures and ultraviolet light, reducing by-product formation and making cleanup easier at the pilot scale. Some halogenated analogues fall short during halide exchange steps or produce too much colored tarring in side reactions, driving up costs through repeated purification. Careful control of starting material and real-time reaction monitoring gives our product a reliability that excites veteran synthesis chemists.

    End Uses: Where the Chemistry Makes a Difference

    1,6-Dibromoperfluorohexane doesn’t end up in consumer products, but the specialty fields that seek it out care deeply about every attribute. Its use traces to fine-tuned fluorinated surfactants, oil- and water-repellent coatings, and as a controlled starting material for syntheses of even more complex molecules. Advanced electronics manufacturing rides on the back of such perfluorinated intermediates—the reliability of etch-resistant, low-dielectric coatings and certain cable jacketing comes back to the starting purity and handling of every kilogram shipped.

    We’ve fielded requests from polymer chemists fine-tuning specialty elastomers or creating graft copolymers where chain-end modification with bromine is a critical element. Biotech teams exploring high-value-labeled probes count on our attention to residual metals and volatility. Environmental research groups looking for standards to assess persistence also demand product consistency, allowing them to compare apples with apples across batches and research labs. Sometimes our customers’ applications surprise us; a recent collaboration involved a pharmaceutical intermediate that pushed the limits of halogen exchange chemistry, only enabled by the high selectivity from clean, well-made starting material.

    Performance Under Pressure: Scaling Up Without Compromise

    Manufacturers understand that things which work in a flask may fail on the ton scale. Our team has run full-scale fluorination and bromination lines for years, with a rhythm guided by chemistry but tuned through pragmatism: line fouling, batch-to-batch heat transfer, and keeping a lid on fugitive emissions. Repeated experiments at kilo scale have taught us where fouling or degradation creeps in and how trace contaminants tip over into costly downtime. Our operators know from experience how 1,6-Dibromoperfluorohexane vaporizes, what hints at premature decomposition, and where venting systems need reinforcement to keep scrubbers clean.

    Past attempts to take shortcuts often delivered hard lessons. Running the reaction a little too hot, or letting a condenser run dry, resulted not only in lost product but also in headaches for downstream users who needed every kilogram to perform as promised. We evolved an internal rhythm: planning maintenance based on subtle changes tracked by sensors, and logging every pressure bump and temperature swing for later review. Customers shop for this molecule not out of habit, but through word of mouth: one failed batch elsewhere becomes a multi-thousand-dollar setback. Those who have switched suppliers mid-run due to inconsistency often return after a round of requalification headaches.

    Differences from Related Products: Why Chain Length and Purity Count

    Fluorine chemistry doesn’t always follow the rules taught in the textbooks. With perfluorinated alkyl dibromides, chain length changes more than just boiling point or solubility. 1,6-Dibromoperfluorohexane sits in a unique window between the more volatile tetrafluoro variants (such as 1,4-dibromoperfluorobutane) and bulkier longer-chained analogues (like 1,8-dibromoperfluorooctane). Too short, and volatility creates storage and handling headaches; too long, and solubility and processability drop off. The six-carbon version balances these extremes, giving manageable viscosity, sufficient reactivity, and better process yields for mid-chain polymer modification.

    Chain purity matters more than non-practitioners think. A stray odd-carbon impurity results not just in regulatory paperwork but also in unpredicted performance failures. The learning curve here is steep—fluctuating chain purity slips through only to appear weeks later as variability in a batch of specialty monomers. We’ve spent years refining feedstock sources, developing batch traceability, and testing finished goods at every stage to stamp out these headaches at origin.

    Usage Insights: Real-World Chemistry in Action

    On paper, 1,6-Dibromoperfluorohexane looks a simple molecule: two bromines, six carbons, all carbons fluorinated. In the lab and plant, usage isn’t just a matter of mixing and waiting. Chemists tap its strong terminal bromine leaving groups for nucleophilic substitution or metal-mediated coupling. The fluorocarbon backbone resists unwanted hydrogen abstraction, letting reactions run cleaner and longer. This means sharper endpoints, higher isolated yields, and less time spent purifying. Polymer modifications are particularly robust, since the product doesn’t introduce color bodies or side-chain segments that later spoil transparency or flexibility.

    In the field, we’ve seen project teams develop fluorinated blocking agents tolerant of extreme chemical stress. Their application in microelectronics highlights the expectation that every supplied batch delivers the same reaction profile—variation leads to delays measured in millions of dollars. In surface science R&D, a single odd impurity or incomplete terminal functionality shows up as blotches and streaks on test surfaces. As a manufacturer, we’ve witnessed these realities firsthand and responded by dialing in both analytical support and hands-on technical guidance.

    Meeting Today’s Challenges: Environment and Safety

    Handling perfluorinated compounds calls for thorough attention, not just in health and safety compliance but also in reducing environmental impact. Years ago, our plant transitioned from open, benzene-based reactions to closed-loop systems that trap and recycle process solvents. We monitor every solvent drum and distillation run, because even minor leaks add up over time. Our waste streams run through advanced scrubbers and have regular third-party audits. Our people live near our plants, so doing things right isn’t just about regulatory boxes; it’s about earning and keeping trust every day.

    Brominated intermediates draw scrutiny from researchers and agencies tracking PFAS risks. Our commitment is to minimize release in air and water, capture every offcut, and track materials from feedstock to barrel. The chemistry here gets complicated, fast—many regulatory schemes lag behind the realities of industrial-scale synthesis. We work with all our downstream partners to document uses, conduct degradation studies, and support end-of-life management wherever possible. Guidance for safe handling gets shared promptly, not hidden in footnotes. We adapt as standards evolve, tweaking process steps to incorporate safer catalysts or alternative solvents as science advances.

    Why We Keep Listening: Lessons from the Floor and the Field

    Manufacturing 1,6-Dibromoperfluorohexane taught us not to take anything for granted. In the early years, an unnoticed valve leak or a slow shift in supplier quality caused headaches—not always right away, but revealed in the next batch, or in a call from a frustrated R&D chemist trying to puzzle out poor conversion rates. Now, we sit down with product users, walk through their process flows, and help them troubleshoot as chemistry partners, not just suppliers. If someone’s extraction breaks down or their columns get fouled, we can map it back through our own data, and work side-by-side to spot the root cause. This collaboration means continuous improvement, and we see it reflected in repeat orders, fewer complaints, and stronger technical partnerships.

    Staying connected to the science community means we notice when new applications emerge—whether a university research group demonstrates a novel functionalized coating, or an established electronics supplier transitions to new manufacturing schemes. Drawing from decades of hands-on plant operation lets us anticipate customer needs. If a certain impurity profile requires a change in drying protocols, or a new end-use raises a question about peroxide sensitivity, we’re equipped to offer concrete guidance, rooted in practical experience rather than theory.

    Looking Ahead: Real-World Growth and Responsibility

    In the world of specialty fluorinated products, the only constant is change. Performance specs get tougher. Regulatory requirements shift. Chemistry evolves as new use cases pop up across industries. We keep investing in equipment, people, and training to ensure that every shipment of 1,6-Dibromoperfluorohexane lives up to both today’s expectations and tomorrow’s possibilities. From the plant manager’s desk to the loading bay, a sense of responsibility runs through it all; this manifests in tighter material tracking, more rigorous documentation, and open channels with scientists and procurement teams using our product in their most demanding projects.

    To us, every container reflects years of dedication—a product of many sleepless nights troubleshooting sticky batch reactors, upgrading air handling, and debating the best feedstock suppliers late into the evening. Success isn’t just about reaching technical spec, but about standing behind every gram shipped, ready to talk chemistry, troubleshoot, and keep the pipeline running for those who expect the best when genuine 1,6-Dibromoperfluorohexane is called for.