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HS Code |
109365 |
| Chemical Name | 1,5-Dimethylpyrazole |
| Molecular Formula | C5H8N2 |
| Molecular Weight | 96.13 g/mol |
| Cas Number | 67-51-6 |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 180-182 °C |
| Melting Point | 14-17 °C |
| Density | 0.96 g/cm3 (at 20 °C) |
| Solubility In Water | Slightly soluble |
| Refractive Index | 1.491 |
| Pka | 13.4 (for conjugate acid) |
| Flash Point | 76 °C (closed cup) |
| Smiles | CC1=CN(N=CC1)C |
| Pubchem Cid | 11618 |
| Ec Number | 200-654-8 |
As an accredited 1,5-Dimethylpyrazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1,5-Dimethylpyrazole, 100g, is packaged in a sealed amber glass bottle with a chemical-resistant screw cap and hazard labeling. |
| Shipping | **Shipping Description for 1,5-Dimethylpyrazole:** 1,5-Dimethylpyrazole is shipped in tightly sealed containers, protected from moisture and ignition sources. Store in a cool, well-ventilated area. Ensure compliance with local and international regulations. Handle with appropriate personal protective equipment (PPE). Label packaging with chemical identity, hazard symbols, and emergency contact information during transport. |
| Storage | 1,5-Dimethylpyrazole should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from sources of ignition, heat, and incompatible substances such as oxidizing agents. Protect from moisture and direct sunlight. Clearly label the storage area and restrict access to authorized personnel. Always follow local regulations and the manufacturer's safety data sheet (SDS) recommendations. |
Applications of 1,5-Dimethylpyrazole in Industrial ManufacturingAs a direct manufacturer of 1,5-Dimethylpyrazole, we support leading industrial partners in leveraging this specialized building block across high-value downstream sectors. Our production adheres to stringent quality controls designed for demanding technical specifications, ensuring reliability and traceability for each industry’s unique requirements. 1. Polyurethane Systems: Isocyanate Reaction InhibitionLarge-scale producers in the polyurethane foam and elastomer sector depend on 1,5-Dimethylpyrazole as a selective blocking agent for isocyanates. By integrating this material at the prepolymer stage, manufacturers control isocyanate activity, ensuring extended shelf-life for isocyanate-terminated resins and consistency in curing profiles for flexible, semi-rigid, and rigid systems. The compound’s blocking and deblocking temperature characteristics play a key role in customizing reactivity for automotive, construction, and appliance applications, supporting advanced formulations that demand precise kinetics and thermal stability. Industry compliance standards
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2. Agrochemical Synthesis: Active Ingredient IntermediateProducers in the crop protection industry use 1,5-Dimethylpyrazole as a core intermediate and blocking agent in the synthesis of active ingredients, most notably in nitrification inhibitor classes. This compound’s controlled release properties and electron-donating character offer superior design freedom in manufacturing modern agricultural formulation types, especially where precise isomer purity and stability are mandatory throughout multi-step production involving condensation, cyclization, or oxidation reactions. Industry compliance standards
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3. Pharmaceutical Intermediate ManufacturingIn the pharmaceutical chemicals sector, 1,5-Dimethylpyrazole functions as a key intermediate in the custom synthesis of heterocyclic drug candidates and APIs. Its unique substitution pattern provides selectivity and stability in building high-purity heteroaromatic backbones essential for anti-inflammatory, CNS-active, or metabolic disorder therapy classes. Our process enables high batch-to-batch consistency, benefitting stringent pharmaceutical GMP and regulatory documentation for audit trails and export approval. Industry compliance standards
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4. Specialty Coatings: Heat-Activated Crosslinkers1,5-Dimethylpyrazole supports specialty coating manufacturers as a blocking component in single-pack, heat-curing crosslinker systems based on polyurethane or epoxy chemistry. By modulating latency through selective deblocking, it allows extended pot-life and controlled network formation during the stoving or baking of industrial finishes on metal, composites, and plastics. Its reactivity profile enables robust storage stability at ambient temperature and sharp performance tuning for low-VOC and rapid-cure coatings under automotive and general industrial specifications. Industry compliance standards
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5. Electronics Encapsulation: Curing Agent for MicroelectronicsAdvanced electronics and microelectronics manufacturers employ 1,5-Dimethylpyrazole as a blocking agent in the formulation of polyurethane or epoxy encapsulation systems. Its controlled reactivity during thermal curing confers precision in pot-life extension and minimizes premature reaction during semiconductor device packaging or assembly operations. High electrical insulation requirements and strict trace impurity regulations in this sector make process consistency and traceability vital aspects of raw material supply. Industry compliance standards
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Competitive 1,5-Dimethylpyrazole prices that fit your budget—flexible terms and customized quotes for every order.
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Working in chemical manufacturing, we've spent years refining the synthesis of specialty heterocyclic compounds like 1,5-Dimethylpyrazole. This compound attracts attention in agricultural chemistry, advanced materials research, and practical industrial settings. Every batch from our reactors reflects tight process control and a focus on reproducibility. Our teams monitor every stage—right from raw material checks through to the finished product—because both purity and absence of residual contaminants make all the difference downstream.
A strong record for dependable deliveries backs our name. Customers rely on us because we have the infrastructure, the skilled staff, and decades of production know-how. Over the years, requests for tailored particle sizes or specific moisture profiles gave us insights that only hands-on manufacturers can provide. Small variations on paper multiply into big differences in the field. When the crop protection sector scaled up the use of functionalized pyrazoles, the rush for cleaner, more predictable intermediates got real. Labs wanted solid results on every trial run and product developers needed uniform performance, not just theoretical purity. That’s where practical experience at scale sets us apart from resellers.
Our regular specification for 1,5-Dimethylpyrazole comes as a white to slightly off-white crystalline solid. Typical purity exceeds 99% by gas chromatography, confirmed across multiple lots. Moisture content remains controlled below 0.2% at dispatch—vital for users in sensitive syntheses. Deliveries come in glass or high-integrity plastic containers, sealed against environmental ingress, because this substance is slightly hygroscopic. Physical consistency is checked batch by batch. Particle sizes generally stay well below 500 microns unless a customer requests otherwise. Over time, this granular attention prevents sticking, clumping, or slow dissolution in manufacturing feeds.
No process ever goes perfectly without good documentation. Alongside our shipments, we provide every batch certificate with precise analytical data—total impurities, water content, GC spectra. Repeat customers know that if a concern pops up in the lab, we answer fast with analytical support based on our in-house data. Years of experience tells us this builds trust where generic offerings fall short.
Much of the demand for 1,5-Dimethylpyrazole comes from the crop enhancement sector. It plays a starring role as a nitrification inhibitor, often combined with ammonium-based fertilizers. The functional mechanism concerns blocking soil bacteria from converting ammonium into nitrate, which helps slow unwanted nitrogen loss by leaching or denitrification. Plants benefit when nitrogen stays available longer in the root zone. Farmers see this in higher yields and reduced input costs, while runoff of nitrates is curbed for better environmental outcomes.
We have worked with innovative fertilizer formulators building new granules, slow-release systems, and liquid injectables. Some lines need quick dispensing with robust physical stability. Others demand suspension in aqueous systems with minimal foaming. Over time, our teams noticed that technical variations—even slight changes in residual catalysts or trace solvents—make a difference for final product stability. Experience guiding customers during upscaling helps preempt those pains, saving months of rework.
Beyond fertilizers, 1,5-Dimethylpyrazole also finds limited but promising use as a building block in pharmaceutical, agrochemical, and fine chemical syntheses. Its symmetrical dimethylation enables controlled substitution and tuning of physical properties in downstream chemistry. Chemists in research settings rely on our detailed specifications to prevent side reactions, especially where catalytic cycles or polymerization steps are sensitive to off-spec raw materials.
In the polymer industry, specialty resin formulators increasingly explore heterocyclic scaffolds like 1,5-Dimethylpyrazole to modify hard/soft segment balances, UV resistance, and color stability. Reliable, reagent-grade material is essential here. Transparency over trace metals, color bodies, and batch-to-batch lot variance helps keep lab data consistent and scale-up less risky.
Some customers approach us with broader requests for pyrazole derivatives. The methyl arrangement on 1 and 5 positions of the ring gives 1,5-Dimethylpyrazole distinct physical and chemical properties not found in other family members. For instance, compared to 3-methylpyrazole or 4-methylpyrazole, this compound melts at a higher temperature and dissolves more slowly in polar solvents. Its symmetrical structure affects how enzymes and reactive intermediates interact with the molecule, which flows into all sorts of practical outcomes. In fertilizer mixes, its stability allows blends that survive wider pH and temperature swings. In organic synthesis, this positioning helps limit unwanted isomerization that can complicate purification runs in the final steps.
We’ve fielded questions about interchangeability—why not swap in a cheaper or more common pyrazole? The truth lies in how unique substitution affects both biological and physical results. Some molecules break down quickly or interact with other actives, risking regulatory or safety issues. We’ve run side-by-side studies with partners testing dinitrogen emissions, ammonia volatilization, and crop uptake. The data tell a clear story: for lasting nitrification control, you want this ring system, not a near match.
This product appeals to users who want absolute clarity on purity, contaminant control, and suitability for application-critical settings. Agrochemical buyers return because they’ve seen what happens when off-the-shelf reagent quality drops into a large batch—unexpected caking, loss of flow, or unexplainable changes in inhibitory action. Pharmaceutical chemists have flagged batch-to-batch “drift” from unpredictable suppliers, which introduces delays during regulatory filings.
We manufacture every lot under closely monitored protocols. Every reactor load undergoes fractionation and solvent removal under reduced pressure, which allows for an isolated end product without residuals left to chance. Over the years, we refined our distillation steps and worked out bottleneck points prone to product darkening or decomposition. That practical legacy translates into real support for end-users looking to avoid production downtime or troubleshooting expensive processes. Our customer service team, working closely with the plant lab, picks up on runs that fall even slightly out of spec—so nothing comes off the line unless it passes scrutiny.
Even looking at packaging and shipment, there’s experience behind those decisions. Losses from moisture pick-up or container breakage haunt newcomers who underestimate just how sensitive 1,5-Dimethylpyrazole can be to improper storage. We get plenty of follow-up calls from buyers elsewhere who ran into trouble after using what looked like a deal on paper, only to discover yellowing or partial hydrolysis mid-way through their season. Our process gives solid shelf stability on warehouse floors and consistent dosing throughout the application window.
We see ourselves less as passive suppliers and more as partners—because we use many of our intermediates ourselves. Whenever a problem occurs in real-world application, odds are we’ve seen it in our own operations. For example, a few years ago, one specialty customer reported unexpected odor formation in a liquid nitrogen stabilizer containing 1,5-Dimethylpyrazole. After investigating at both ends, we traced it to subtle equipment fouling at their blending plant, which amplified trace decomposition. By sharing analytical tips and cleaning protocols borrowed from our facility, we helped them solve a recurring issue nobody had anticipated in small batches.
Process scale-up brings challenges. Early on in our own history, yield losses and variable purity stemmed from reactor temperature gradients that couldn’t be spotted using bench-scale thermocouples. Course corrections around jacketed reactor design and inline monitoring turned that around, which now gives us the productivity and consistency to compete worldwide. That kind of lesson only comes from direct experience—something a third-party trader never faces—so we know where the stumbling blocks lurk.
We’ve been active in regulatory dialogue, both supporting data collection for environmental risk assessment and sharing best practices with industry groups. Tracking trace residuals, packaging integrity, and shelf-stability tests pays off not only for compliance but for ongoing customer confidence.
Most new applications for 1,5-Dimethylpyrazole stem from creative work in the lab, where research chemists push for greener, more effective processes. We respond with transparency—sharing as much of our analytical work and previous experience as proprietary regulations allow. Startups seeking to design next-gen controlled-release fertilizers consult with us upfront, so their pilot trials use consistent material, not a moving target. We also offer technical advice on blending, handling, and safe storage for larger bulk conversions.
Advanced users in resin development and polymer modification benefit from our willingness to conduct off-line compatibility testing. We welcome small-scale sample requests, because real-world testing in the customer’s line almost always uncovers nuances you can’t see on the specification sheet. Decades of interaction with research teams taught us where questions—like reactivity under heat or color change on extended exposure—tend to arise. That kind of feedback loop between lab and plant speeds up development for both sides.
Manufacturing any reactive intermediate brings environmental and safety responsibilities. 1,5-Dimethylpyrazole, although relatively low hazard, requires responsible handling and waste management. Over years of operation, we’ve prioritized closed-loop solvent recovery, exhaust capture technology, and comprehensive monitoring on our production lines. This adds time and cost to each batch, but we’ve found it pays off in consistent product quality and community trust. Repeat audits by both internal and external reviewers reinforce our focus on compliance and sustainability.
Many customers ask us about compliance documentation for their own regulatory filings. Our team prepares full environmental and safety dossiers, including detailed breakdowns on byproducts, VOC potential, and best storage practices. Agrochemical producers working at global scale appreciate the head start this gives them in environmental risk review. Because we refine and test every aspect of the production ourselves, no downstream user is left guessing what went into the drum they receive.
Our support extends after the sale. We field queries about safe disposal, accidental spills, or off-spec batches—even years after delivery. Local policymakers and trade associations consult our experts for input on evolving restrictions and sustainability targets. This collaborative approach reduces risk of compliance headaches and drives smarter use in the supply chain.
As demand for more precise, environmentally friendly chemical additives expands, the pressure to innovate reliable, greener synthesis routes grows as well. Research in catalyst recycling and solventless production continues, even though the scale-up pathway to industrial yields remains a challenge for all manufacturers in this field. We share updates with our customers—including setbacks and incremental advances—because the industry as a whole benefits from open communication.
Automation and improved in-line monitoring already reduced the scope of human error and batch-to-batch variability in our own facility. Still, tight global supply chains present risks in sourcing high-purity starting materials. In the past, supply disruptions forced ad hoc adjustments and troubleshooting at short notice—something we manage now by stocking extra, qualifying secondary sources, and keeping strategic reserves of key reagents.
One ongoing concern comes with the rise in purity expectations in pharmaceutical and electronic chemical markets. Trace-level contaminant control now calls for advanced separation and detection technology, which drives up operational costs and demands new analytical skills. Training our technical teams and investing in the latest GC-MS equipment serves both safety and business needs, because modern chemistry users will not compromise on quality for critical applications.
Users rely on consistency, but innovation pushes boundaries. Some customers test alternative uses for 1,5-Dimethylpyrazole in specialty catalysts, corrosion inhibitors, and advanced polymer blends. These applications share a demand for low-residual, low-odor, and thermally stable material. We invest in small-batch pilot runs and reserve production slots for experimental partners, because progress in chemistry depends on agility and willingness to adapt established methods.
Manufacturers differ from brokers in more than just scale. Through long-term supply contracts, custom packaging options, and ongoing technical support, we create true partnerships with our clients. This pays dividends at times of market tightness, regulatory change, or shifts in application requirements. Customers who started with a few kilos for formulation trials stay for multi-tonne agreements, because the same care and responsiveness exist at both ends of the scale.
Our focus on transparency and support builds trust. From initial project consultation through post-delivery troubleshooting, we provide clear points of contact, access to lab data, and practical advice. We invest in continuing education for our staff and our customers—helping with everything from transitioning to more sustainable formulations to managing the documentation for new regulatory frameworks.
Every technical success we record in the field reflects cumulative expertise gained by direct, hands-on manufacturing. Rather than just selling a chemical, we share in the risks, adapt to shifting challenges, and remain committed for the long run. That’s how we see the role of a manufacturer—and why experienced customers see the real value behind every bottle, drum, or custom lot of 1,5-Dimethylpyrazole we produce.