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1,4-Pentadien-3-Ol

    • Product Name 1,4-Pentadien-3-Ol
    • Alias 3-Hydroxy-1,4-pentadiene
    • Einecs 210-769-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    491563

    Iupac Name penta-1,4-dien-3-ol
    Molecular Formula C5H8O
    Molar Mass 84.12 g/mol
    Appearance colorless liquid
    Boiling Point 111-113 °C
    Density 0.859 g/cm3
    Solubility In Water miscible
    Melting Point -90 °C (approximate)
    Cas Number 766-13-6
    Refractive Index 1.441
    Flash Point 23 °C
    Structural Formula CH2=CH-CH(OH)-CH=CH2

    As an accredited 1,4-Pentadien-3-Ol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 mL of 1,4-Pentadien-3-ol; tightly sealed, labeled with hazard warnings and handling instructions.
    Shipping 1,4-Pentadien-3-ol should be shipped in tightly sealed containers, clearly labeled, and protected from heat, moisture, and incompatible materials. Use appropriate cushioning and secondary containment to prevent leaks. Transport should comply with local and international regulations for hazardous chemicals, including documentation and emergency response information as required for safe handling.
    Storage **1,4-Pentadien-3-ol** should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and direct sunlight. Keep the container tightly closed and away from incompatible materials such as strong oxidizers. Store in a chemical-resistant container and clearly label it. Follow all safety guidelines and local regulations for flammable liquids and hazardous chemicals.
    Application of 1,4-Pentadien-3-Ol

    Applications of 1,4-Pentadien-3-Ol in Industrial Manufacturing

    As a direct manufacturer of high-purity 1,4-Pentadien-3-Ol, we support a select set of specialized downstream industries where this unique intermediate serves as a critical building block for advanced organic synthesis. Our customers leverage the distinctive dual terminal diene and primary alcohol functionalities for precision-controlled processes in the fine chemical, agrochemical, pharmaceutical, and polymer additive fields. The following sections detail practical, real-world applications, including compliance guidelines, recommended formulation levels, process points of incorporation, and representative end products.

    1. Synthesis of Pharmaceutical Intermediates

    API contract manufacturers incorporate 1,4-Pentadien-3-Ol as a C5 precursor in the construction of complex chiral intermediates, especially in macrolide, steroid, and specialty antiviral active pharmaceutical ingredient (API) routes. Its reactivity supports precision enantioselective functionalization while maintaining structural integrity throughout multistep synthesis chains.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • EU GMP Part II for starting materials in API production
    • USP-NF monographs for related pharmaceutical intermediates
    • FDA 21 CFR Part 211 (Finished Pharmaceuticals) – pertinent when used in regulated end products

    Typical usage ratio

    • 5–25 mol% of the core substrate step (dosage set by synthetic route optimization, target yield, and impurity profile constraints)

    Downstream process integration

    • Introduced during Grignard or Wittig-type C–C coupling reactions
    • Reacted in controlled alkylation or oxidation steps as a chain extender or terminal functional group source
    • Integrated into flow chemistry modules for continuous processing of high-potency intermediates

    Final product types

    • Specialty API intermediates for macrolide antibiotics
    • Steroidal intermediate scaffolds
    • C5-functionalized antivirals (e.g., nucleoside analogues)
    • Peptide macrocycle building blocks

    2. Agrochemical Synthesis: Pheromone and Biopesticide Precursors

    Crop protection manufacturers utilize 1,4-Pentadien-3-Ol in the production of advanced pheromonal lures and biopesticide actives. Its structure enables selective diene alcohol functionalization for producing long-chain pheromone mimics and insect growth regulators, supporting sustainable agriculture with low environmental residue.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • OECD Guidelines on Pesticide Formulation Registration
    • ISO 9001: Quality Assurance in fine agrochemical production
    • REACH (EU) Annex IV & V for low-toxicity biopesticide substances

    Typical usage ratio

    • 2–20 wt% of target pheromone or biopesticide batch (proportion defined by isomer target and overall reaction pathway control)

    Downstream process integration

    • Inserted as diene alcohol in cross-metathesis to generate conjugated systems
    • Chain-extended by hydroformylation or tandem isomerization to deliver the desired active compound
    • Processed in batch reactors equipped for odor-critical and low-impurity production runs

    Final product types

    • Moth (Lepidoptera) pheromone analogues for mating disruption traps
    • Long-chain fatty alcohols used in integrated pest management
    • Precursor molecules for juvenile hormone analog biopesticides
    • Insect attractant microcapsules

    3. Specialty Polymer and Resin Modification

    Producers of specialty polymers and performance resins value 1,4-Pentadien-3-Ol for its ability to introduce dual unsaturation and alcohol groups into prepolymer chains, resulting in custom cross-linking and enhanced flexibility. Its incorporation supports the formulation of elastomers, UV-curable coatings, and functional copolymers with improved impact or weather resistance.

    Industry compliance standards

    • ISO 14001: Environmental Management in resin manufacturing
    • RoHS Directive (EU) for electronics-compatible coatings
    • ASTM D256 (Impact Resistance) and D412 (Tensile Properties) for elastomeric products
    • GMP for indirect food contact plastics (as per FDA 21 CFR 177.2600)

    Typical usage ratio

    • 0.5–5 phr (parts per hundred resin) with adjustment based on desired cross-link density and mechanical property profile

    Downstream process integration

    • Added during prepolymer formation in the reactor before cross-linker introduction
    • Reacted under UV or peroxide initiation in oligomeric resin blends
    • Utilized in copolymerization alongside other functional monomers for tailored property modification

    Final product types

    • UV-curable coatings for electronics and automotive plastics
    • Impact-modified polyurethanes and elastomer blends
    • Flexible adhesive backings for specialty tapes
    • Weather-resistant copolymer films

    4. Fragrance and Flavor Synthesis

    Producers in the fragrance and food additive sectors utilize 1,4-Pentadien-3-Ol as a critical intermediate during the formation of complex aroma chemicals and natural-like flavor molecules. Its unique C5 unsaturated backbone supports the biosynthetic mimicry and functionalization needed for high-intensity, thermally-stable flavor ingredients and long-lasting fragrance bases.

    Industry compliance standards

    • IFRA Code of Practice for fragrance ingredient safety assessment
    • FEMA GRAS (Flavor and Extract Manufacturers Association – Generally Recognized as Safe) status for direct flavor use
    • ISO 9001 for quality assurance in food and cosmetic ingredient manufacturing
    • EU Regulation (EC) No 1334/2008 on flavorings and certain food ingredients

    Typical usage ratio

    • 0.1–1.5% (w/w) in synthetic aroma compound production (final dosage refined by organoleptic panel and volatilization behavior)

    Downstream process integration

    • Introduced in esterification or cyclization reactions to generate macrocyclic musks
    • Utilized during controlled hydrogenation or oxidation to yield specific aldehydes and lactones
    • Blended in pilot fragrance manufacturing units for formulation standardization and batch traceability

    Final product types

    • Macrocyclic musk aroma chemicals
    • Green, herbal, and fruity flavor compounds (e.g., C5-alcohol notes)
    • Fine fragrance bases for personal care and detergents
    • Food flavoring blends for beverages, confectionery, and bakery applications
    Free Quote

    Competitive 1,4-Pentadien-3-Ol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

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    Certification & Compliance
    More Introduction

    Introducing 1,4-Pentadien-3-Ol: A Manufacturer’s Perspective

    Molecular Precision, Practical Needs: Crafting 1,4-Pentadien-3-Ol

    Every day on our production lines, we see the value and versatility of 1,4-Pentadien-3-Ol. This compound, which we synthesize in our reactors using tightly controlled processes, fulfills a quiet but important role across chemical synthesis, research, and commercial production. Its structure—a five-carbon chain with two conjugated double bonds and a single hydroxyl group at the midpoint—gives it an edge in reactivity that isn’t found in most common alcohols or simple dienes.

    Our model of 1,4-Pentadien-3-Ol focuses on purity and stability. Through distillation and purification, we deliver a colorless to slightly amber liquid, free from residual reactants and by-products. Many buyers in recent years have moved away from off-spec materials that introduce unwanted impurities, so we keep our process tuned for a purity often exceeding 98%. This purity supports smooth progress in downstream reactions, especially where sensitive catalysts or high-performance products are involved.

    Where Practicality Meets Application: Usage Realities

    Researchers and industrial chemists come to us for 1,4-Pentadien-3-Ol for a handful of good reasons. The compound acts as a valuable intermediate in organic synthesis. Its diene moiety supports cycloaddition chemistry, such as Diels-Alder reactions. The primary alcohol group at the third carbon offers a handle for selective functionalization or polymerization. Over the past decade, we’ve seen it incorporated into syntheses of fragrance ingredients, specialty monomers, and both pharmaceutical and agrochemical intermediates.

    In our experience, the market for conjugated dienols is driven by two classes of application: those seeking reactive building blocks with dual functionality, and those needing materials that can undergo controlled polymerization. Styrene and butadiene dominate the large-scale synthetic rubber sector, but for specialty elastomers or research polymers, 1,4-Pentadien-3-Ol offers an alternative starting material. Its hydroxyl group enables further linking or crosslinking, while its unsaturation delivers chemical flexibility.

    Because the chemistry is nuanced, we maintain a team focused on technical support and troubleshooting for customers exploring novel uses. It’s not unusual to receive requests from downstream R&D units, seeking insight into purification protocols, storage considerations, or reactivity patterns. We share practical guidance based on our own operational experience—ranging from reaction conditions to safety handling. Over the years, we learned that even a trace of peroxide in storage can spoil an entire batch, so we advise customers on inert gas purging and optimal container selection.

    Key Specifications and the Realities of Quality Control

    While some producers treat specifications as a document for filing, we treat them as a set of commitments. The most critical specs for 1,4-Pentadien-3-Ol always revolve around purity, moisture content, color index, and residual solvents. GC analysis forms the backbone of our lot-release process; we invest heavily in chromatographic calibration to catch anomalies early.

    For customers using 1,4-Pentadien-3-Ol as a precursor in sensitive syntheses, a few tenths of a percent of water or unknown by-products can spell disaster. Over the past five years, we responded to changing customer needs by adding online real-time moisture monitors, as well as additional fractionating columns aimed at stripping volatile impurities. Our in-house QA chemists pull random samples on every shift, reinforcing strong internal accountability. More than once, this has avoided downstream headaches for our largest buyers.

    Product stability in storage remains a constant concern. Oxygen and light both threaten deterioration, especially for materials with unsaturation like this one. Based on our long production and storage trials, we advise all partners to store the alcohol under dry nitrogen, in amber glass or stainless steel, away from heat and direct sunlight. We’ve tracked product characteristics for months at a time, confirming that proper storage preserves both reactivity and clarity. These measures aren’t just about safety—they directly translate into fewer failed reactions and more reliable outcomes for our customers.

    What Sets 1,4-Pentadien-3-Ol Apart?

    Chemists and purchasing specialists often ask why they’d select this compound over more common or less expensive alternatives. The unique combination of a conjugated diene and a central alcohol cannot be easily replicated with mixtures: it delivers site-specific reactivity that enables one-pot syntheses, cross-coupling, or even sequence-controlled co-polymerization.

    From a synthetic perspective, neither simple allyl alcohol nor polyenes without functional groups can deliver the performance needed for specialty product development. For example, allyl alcohol lacks the diene system, limiting its utility in cycloaddition chemistry. Conversely, 1,3-butadiene or 1,5-hexadiene don’t have the hydroxyl handle at C-3, restricting their adaptability in functional materials. We work with labs developing novel coatings, plasticizers, and even electronic intermediates; many report that attempted substitutions usually fail to yield the same selectivity and yield as 1,4-Pentadien-3-Ol.

    This molecule fits a niche, especially in advanced research or commercial settings where unique intermediate skeletons add value. The push toward greener processes has also amplified interest, since a multifunctional reagent often reduces the number of synthetic steps, cutting solvents and minimizing waste. We have documented cases from pharmaceutical partners who switched to 1,4-Pentadien-3-Ol during route optimization—reporting improved atom economy and lower overall process mass intensity compared to multi-step workarounds.

    Practical Challenges We Face During Production

    Manufacturing 1,4-Pentadien-3-Ol at scale presents distinct challenges. The synthesis route most frequently used involves controlled partial reduction and purification sequences. Batch-to-batch consistency requires rigorous monitoring; trace by-products, originating from over- or under-reduction, accumulate quickly if parameters drift even slightly.

    As a direct producer, we grapple with raw material variability and the ongoing cost and complexity of analytical confirmation. Feedstock pricing swings in the petrochemical sector ripple straight through production costs. Workforce training also matters: handling volatile dienes takes skill, and we invest in regular upskilling to prevent incidents and assure high yields. By maintaining a vertically integrated setup, we maintain alignment between raw material input and final product requirements, avoiding reliance on unpredictable intermediaries.

    Regulatory scrutiny around specialty chemicals invites transparency and documentation. We keep detailed process logs and maintain open channels with inspectors. Regular equipment upgrades—like anti-static measures on transfer lines—limit risk, while improving recovery rates. These investments aren’t just compliance-driven. Over time, stronger quality and safety protocols have helped reduce rework and improve shipment punctuality, building a reputation for reliability among our long-term partners.

    Environmental and Safety Awareness on the Ground

    On the factory floor, sustainability is more than a talking point. Waste minimization matters. Our process design aims to maximize conversion efficiency and reuse unreacted starting materials whenever feasible. In past years, we revamped our solvent recovery systems. Rather than sending solvent-rich waste away, we cycle it through tertiary purification, cutting solvent consumption by over a third.

    Worker safety runs parallel to process sustainability. Open handling of unsaturated, flammable organics brings risks. We installed continuous vapor monitoring, automated shutoff valves, and strictly adhere to closed transfer systems. Many on our floor have handled 1,4-Pentadien-3-Ol daily for over a decade, so practical knowledge of its hazards informs both protocol and emergency planning. In our experience, clear communication and on-site training prevent nearly all incidents—people respect what they understand.

    Packaging represents another arena where practicality and safety intersect. We use corrosion-resistant containers, fitted with tamper-evident seals. Incoming drums get batch-tracked from the fill line to the loading dock. Before shipment, we run a battery of checks, looking for any sign of contamination or seal compromise. Over time, this upfront rigor translates into fewer claims, smoother logistics, and greater buyer confidence.

    Supporting End-Users: Knowledge in Action

    We learned long ago that our job does not end at the loading dock. Questions from formulators, contract manufacturers, and R&D groups arrive regularly: optimal stoichiometry, reactivity under varying conditions, compatibility with other reagents. Our technical service staff draws from real-world experience and hands-on bench work, not just manuals. Advice on inert atmosphere methods, temperature profiles, or even by-product management draws directly on decades of operation.

    End-users often experiment at small scale before scaling up. We advise running pilot reactions under strict exclusion of air and moisture; our own trials confirm that even small contaminants can derail delicate syntheses. If a customer faces unexpected reactivity, process technicians offer alternatives or suggest pre-purification steps. Our willingness to share workflow improvements helps customers avoid expensive failures. Over the years, partnerships forged on expertise—not just product sales—have opened doors to joint development and innovation.

    Market Adaptation and Future Directions

    As research priorities shift toward renewable pathways and circular chemistry, specialty intermediates like 1,4-Pentadien-3-Ol play a growing role. Today’s buyers value traceability, performance, and supply assurance. By maintaining direct manufacturing and full transparency over our process, we answer these needs without outsourcing key steps or quality controls.

    We keep a close eye on regulatory developments. Environmental, health, and safety expectations rise steadily, so process modifications are ongoing. We invest in greener reductants, capture and abatement technologies, and electronic recordkeeping. Our compliance team has grown in parallel with QC. Changes in international shipping or customs requirements? We handle these with preparation, documentation, and dialogue.

    Feedback from academic and industrial researchers points toward new usage horizons for 1,4-Pentadien-3-Ol. Custom resins, specialty composites, and chiral intermediate development all show growing promise. Our production flexibility lets us support gram-scale analytical needs as well as multi-ton batches for plant-scale production. That flexibility comes from deep experience with the molecule, its handling, and its quirks.

    No Substitute for Experience: Partnering for Success

    Looking back, our experience with 1,4-Pentadien-3-Ol underscores a lesson we see across specialty manufacturing: skillful synthesis, rigorous quality control, and transparent support define a successful supplier. The compound offers paths forward for innovators in fine chemicals, materials science, and applied research. By staying close to production, invested in practical solutions, and tuned to industry trends, we help unlock these opportunities for everyone who counts on us for their critical building blocks.

    Our journey with this molecule continues. Demand grows, chemistries evolve, and safety, quality, and sustainability march forward. Every drum that leaves our site reflects not just raw output but years of continuous learning and adaptation. That commitment remains our promise to every partner who relies on us for the distinctive advantages of 1,4-Pentadien-3-Ol.