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1,4-Dibromopentane

    • Product Name 1,4-Dibromopentane
    • Alias Pentamethylene dibromide
    • Einecs 211-221-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    399120

    Name 1,4-Dibromopentane
    Molecularformula C5H10Br2
    Molarmass 229.94 g/mol
    Casnumber 110-52-1
    Appearance Colorless to pale yellow liquid
    Density 1.637 g/cm3 (at 20°C)
    Boilingpoint 218–220 °C
    Meltingpoint -19 °C
    Refractiveindex 1.494
    Flashpoint 110 °C
    Solubilityinwater Insoluble
    Odor Characteristic
    Vaporpressure 0.3 mmHg (at 25°C)

    As an accredited 1,4-Dibromopentane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,4-Dibromopentane is supplied in a 500 mL amber glass bottle with a secure screw cap, labeled with hazard warnings.
    Shipping 1,4-Dibromopentane is typically shipped in tightly sealed containers made of compatible materials, such as glass or HDPE, to prevent leaks. It should be kept away from heat, open flames, and oxidizers. During transport, compliance with local, national, and international regulations for hazardous chemicals is required. Handle with appropriate safety measures.
    Storage **1,4-Dibromopentane** should be stored in a tightly sealed container, away from heat, sparks, and open flames. Keep it in a cool, dry, well-ventilated area, and protect it from light and moisture. Store separately from strong oxidizers, bases, and other incompatible substances. Use secondary containment to prevent spills, and label the storage area clearly with appropriate hazard warnings.
    Application of 1,4-Dibromopentane

    Applications of 1,4-Dibromopentane in Industrial Manufacturing

    As the original manufacturer, we provide 1,4-dibromopentane for technically demanding sectors where its specific molecular structure directly impacts downstream performance and synthesis yields. Below we outline key industrial pathways where our material underpins efficient, compliant, and economically valuable production.

    1. Pharmaceutical Intermediate Synthesis

    Downstream pharmaceutical manufacturers use this specialty halide for constructing nitrogen-containing heterocycles and piperidine derivatives, essential in several APIs and auxiliary intermediates. In these processes, batch consistency and impurity control determine compliance and market access, as target molecules frequently enter regulated global medicine supply chains.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • USP and EP monographs for selected intermediates (as relevant to downstream products)
    • EU REACH (1907/2006) registration where applicable
    • FDA 21 CFR part 211 requirements (for final products in the US market)

    Typical usage ratio

    • Added at 0.8 to 1.4 molar equivalents against amine nucleophiles, determined by the selected reaction pathway and target API or intermediate scale

    Downstream process integration

    • Reacted in alkylation stages for ring closure or chain extension, typically in solvent or biphasic systems under inert atmosphere following charge-in of base and nucleophile

    Final product types

    • Piperidine derivatives for CNS APIs
    • Pharmaceutical-grade heterocycles used in anti-infective and cardiovascular drugs
    • Protected intermediates introduced into small-molecule synthesis routes

    2. Agrochemical Intermediate Manufacturing

    Producers of crop protection products and seed treatment chemicals employ this material as a bromoalkylating agent to build specialized building blocks for advanced herbicides and fungicides, where purity and consistent halogen content improve downstream yields and product efficacy.

    Industry compliance standards

    • FAO/WHO specifications for active ingredients (as per downstream product)
    • ISO 9001:2015 quality management
    • EU Regulation (EC) No 1107/2009 on plant protection products
    • Local environmental discharge limits for brominated process streams

    Typical usage ratio

    • Used at 1.0 to 1.3 molar equivalents in nucleophilic substitution or Grignard coupling, aligned with stoichiometric process planning for specific active ingredient scaffolds

    Downstream process integration

    • Introduced during step-growth stages of synthetic organic pathways, following catalyst addition and pH adjustment, with subsequent phase separation and target extraction

    Final product types

    • Precursor intermediates for systemic herbicides
    • Haloalkyl building blocks for new-generation biocidal additives
    • Active moieties in fungicidal seed coatings

    3. Polymer Crosslinking and Chain Extension

    Polymer compounders utilize the unique brominated structure for controlled crosslinking and as a chain extender in synthesizing specialty polyamides and engineering thermoplastics where thermal stability and defined mechanical properties are critical for finished goods serving electronics and automotive markets.

    Industry compliance standards

    • RoHS Directive (2011/65/EU) for electronic components
    • UL 94 safety standard for flammability of plastic materials
    • ISO 9001:2015 for process and QC traceability
    • REACH SVHC monitoring for brominated organic compounds

    Typical usage ratio

    • Incorporated at 1–5% by weight, adjusted according to desired cross-link density, mechanical targets, and melt processing windows

    Downstream process integration

    • Added to mixing and extrusion stages as a chain branching agent prior to addition of catalysts or further monomer feeds; closely monitored to avoid over-crosslinking or gel formation

    Final product types

    • Flame-retardant polyamide blends
    • High-strength thermoplastic housings for consumer electronics
    • Heat-resistant components in automotive electrical systems

    4. Organic Synthesis for Fine Chemical Building Blocks

    Chemical manufacturers use this halogenated pentane to introduce bifunctionality in ligand synthesis, dye intermediates, and specialty surfactant molecules by leveraging its dual-bromo structure for selective anchoring of target functional groups, impacting downstream throughput and value generation.

    Industry compliance standards

    • ISO 14001:2015 for environmental management in fine chemicals
    • Custom specification sheets under NDA for CMO/CDMO projects
    • Compliance with national hazardous waste management and transport codes (e.g., US DOT 49 CFR, ADR in Europe)
    • Registration and notification under REACH for intermediate-only use

    Typical usage ratio

    • Charged at 0.5–1.5 molar equivalents, titrated per design of linker or multi-step construction route; excess may be used to drive complete conversion in some specialty cases

    Downstream process integration

    • Employed in stepwise coupling or alkylation reactions, often in sequential or modular synthesis platforms, with tight reaction parameter control for high-purity isolation

    Final product types

    • Custom chelating ligands for metal complex catalysts
    • Chromophore intermediates for organic pigments or dyestuffs
    • Tailored surfactant precursors for fine chemical and cosmetics formulators
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    Competitive 1,4-Dibromopentane prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    1,4-Dibromopentane: An Inside Look from the Manufacturer’s Perspective

    Introducing 1,4-Dibromopentane: Consistency Rooted in Experience

    Every batch of 1,4-dibromopentane rolling out of our production line carries the imprint of years spent refining both process and product. This compound, with its distinctive five-carbon backbone, dressed up with a bromine atom on each end, doesn’t just pass through our reactors—its production presents challenges that push us to hone our craft. 1,4-dibromopentane offers a level of reactivity in organic synthesis that comes from the confidence of purity. We don’t chase after bells and whistles with this chemical; we focus on practical, reliable performance for chemists who require a straightforward dibromoalkane that doesn’t surprise them with contamination or unwanted side products.

    The standard model we deliver has a molecular formula of C5H10Br2, with a molecular weight tipping the scale at about 243 grams per mole. Each drum, bottle, or bulk tote houses a clear, colorless to pale yellow liquid, typically carrying less than 0.5% impurities, confirmed by rigorous gas chromatography checks on-site. Boiling near 212°C means the material stays well-behaved through standard storage and handling procedures. The density averages 1.52 g/cm³ at ambient temperatures. Packing and transport involve a tight seal and appropriate halogen-resistant lining, and once it lands on a laboratory shelf, customers receive the outcome of our steady improvements in purification.

    Production: Experience Shapes Reliable Chemistry

    Manufacturing 1,4-dibromopentane in-house gives insight beyond what a storefront brochure shows. Sourcing pure pentane feedstock or carefully cracked pentene lets us drive the dibromination reaction under conditions that avoid over-bromination or unwanted rearrangement. Years spent observing how temperature, pressure, and stirring rate affect yield have led us to operate reactors at parameters that keep the product within a tight specification window. The temptation always exists—run reactions longer or hotter to chase conversion rates—but that route only complicates downstream separation.

    What comes out at the end of the process isn’t always perfect. Regular upgrades to our distillation train allow us to squeeze out lighter or heavier haloalkanes, leaving only the targeted 1,4-dibromopentane present in final collection tanks. This facility doesn’t simply bottle the reaction mixture; we take responsibility for trapping and destroying any hazardous vapors and re-using bromine wherever possible. For the rare off-spec batch, rejection happens before anything leaves the compound’s line. Over the years, handling in-house quality rechecks, not just at line-out but again at point of shipment, taught us where problems hide—a big reason our outgoing certificates of analysis aren’t copy-pasted but tied to the actual vessel shipped.

    Applications: Built on Intermediates, Fueled by Utility

    1,4-Dibromopentane’s strongest suit lies in its function as a versatile alkylating agent. In our experience, pharmaceutical chemists use it to construct cyclic compounds, where the pentane chain bridges ring systems without awkward geometry or steric clashes. Polymer manufacturers use the two reactive bromo groups as anchors for growing chains, inserting new functionality at both ends. Research labs exploring new materials keep asking for it, saying that direct dibromoalkanes give them the predictability to tune molecular architecture, especially in the hands of those needing precisely spaced linkers for custom surfactants or ligands.

    Every kilo passing through these doors might end up in a very different downstream product. We’ve seen it head into organic syntheses that build everything from odorants to specialty resins. Some years, the demand tilts toward biochemistry, where the C5-dibromide acts as a scaffold for alkylating amino acids or nucleotides. In recent projects, customers experimented with it to lock organic compounds into targeted conformations or function as a leaving group for more complex substitution reactions. Whenever someone asks why not use a shorter or longer chain, our feedback always returns to the unique chain length of 1,4-dibromopentane—it fits in places butanediol or hexanediol analogues don’t.

    The diversity of uses doesn’t lead us to lose focus on what counts: batch-to-batch uniformity, no unwelcome contamination, and detailed documentation on every shipment. We have learned over decades that it only takes a few ppm of an off-chain impurity to ruin a sequence or introduce regulatory headaches. So for partners counting on stringent quality—be they academic labs or industrial manufacturers—the inside view is one of deliberate, vigilant scrutiny, not just of end-point testing but upstream management of raw materials and processing protocols.

    Comparison: 1,4-Dibromopentane Versus Related Dibromides and Halides

    In specialty chemicals, the devil hides in chain length and substitution pattern. Producers sometimes wonder why customers stick with 1,4-dibromopentane over compounds like 1,2-dibromoethane, 1,3-dibromopropane, or longer-chain analogues. Context matters: 1,2-dibromoethane’s short chain brings added volatility and greater reactivity but threatens side reactions and presents safety liabilities. Switching to hexane or higher homologues adds conformational freedom and makes purification trickier—it takes more effort to keep it within purity standards, given the presence of isomeric side products or byproduct trihalides.

    In practice, feedback from our evaluator labs points out that 1,4-dibromopentane sits in a sweet spot for spaced functionalization without excessive flexibility. The five-carbon backbone gives enough reach for macrocyclization, bipodal ligands, or custom surfactants, without the tangle of branching that longer chains bring. Unlike monochlorinated or mixed-halide intermediates, the dibromo structure grants equal reactivity at both ends, streamlining stepwise synthesis. Our technical team spends time clarifying these distinctions in product calls—most synthetic routes can’t just swap in a structurally similar dihalide without risking yield drops or downstream purity issues.

    Production also differs in non-obvious ways. Handling and disposing of waste from the production of shorter dibromoalkanes often comes with different legal requirements—1,2-dibromoethane, for example, brings up tighter regulatory scrutiny due to its toxicological profile and higher volatility. Our waste management team developed systems over the years to recover and neutralize byproducts while keeping emissions low. These experience-backed changes trickle into how we see cost management—not just for ourselves but, in the end, for our customers needing to prove responsible sourcing.

    Handling Quality at Scale: From Reactor to Final Packing

    Scaling up dibromopentane production introduces challenges that don’t always show up in a lab notebook. Every step—from feeding reactant, controlling bromine flow, to distillation and handling—tests whether a process built for two liters still delivers at two thousand. In dry runs, we paid attention to how slight heat gradients or short-cuts in quenching procedures led to lower-yielding side products. Earlier, we learned the hard way by seeing product discoloration or persistent low-level contamination, then invested in in-line monitoring to catch problems before they show up at the tanker or drum.

    Maintaining this focus took years. We pushed suppliers for raw materials checks, installed feedback control on reaction temperature and agitation, and set up dedicated lines for dibromoalkane runs to prevent cross-contamination from previous productions. Each improvement came after real-world troubleshooting, not textbook theory. The spent bromine or side products aren't a waste stream to ignore; each is accounted for, with bromine capture systems keeping emissions within strict limits, protecting our team and neighboring community.

    It’s easy to promise tight specifications on paper. The reality is, batches can drift if not watched. We’ve seen how minor operational downtime or cleaning lapses elsewhere in the plant seep into product lines—a lesson that brought about more closed-system transfers and regular equipment validation. In practice, quality never comes from inspection alone but from keeping lines running smooth and catching deviation before drums are labeled. The team here spends more time training and retraining than any production manager wants to admit, because a moment’s inattention can have a product fail every customer’s incoming inspection.

    Safety: Risks Don't Hide on the Shop Floor

    Direct experience handling 1,4-dibromopentane—and its close chemical cousins—has shaped our safety practices. Like any reactive brominated hydrocarbon, skin or eye contact can cause severe irritation, so everyone handling the compound gets regular training and must wear personal protective equipment. Vapor management starts before opening a drum. We drill every operator on spill containment and response, and distribution follows the same safety discipline as the original production. Bromine itself, volatile and corrosive, prompted us to invest heavily in fume extraction and air monitoring far above anything minimum rules suggest.

    From years watching how small leaks or spills can create longer-term headaches on both shop floor and in storage, we sidestep risks with secondary containment on tanks, and pressure-relief procedures. Temperature control holds importance both during storage and shipping; dibromopentane doesn’t degrade quickly at room temperature, but prolonged heating or sunlight exposure can yellow the liquid or trigger slow decomposition, adding unwanted byproducts and erosion of purity.

    Shipping logistics matter. We partner only with hazmat-certified carriers, double-check drum and tote labeling, and keep full safety data always on hand. Careful review of transport routes and buffer storage arrangements helps avoid unintended exposure, and regulatory documentation meets destination with actual tested product, not generic compositions. End users placing orders can trace each batch back through our records—not just to start date but to the specific lot of bromine and pentane that began the synthesis.

    Environmental Performance: Making Brominated Chemistry Sustainable

    Reality on the ground means dealing with what bromine-based chemistry leaves behind. We don’t pretend that production is waste-free, but continuous improvements across the plant have slashed emissions and chemical loss, both to air and water. Closed-loop bromine handling systems recapture halogen vapor, sending it back for reuse. Water effluent monitors keep every ppm recorded and reported, with multi-stage scrubbers paired to each vent and every process drain checked and logged.

    The move toward greener chemistry pressures all parts of the industry, not just retail-facing giants. For 1,4-dibromopentane, the pursuit of lower-waste, higher-yield synthesis methods drove us to reevaluate everything from reagents to reactor solvents. Catalytic systems, wherever possible, now earn the space previously filled by stoichiometric approaches. New process pilots replacing older halogenation techniques gave good returns on both safety and efficiency: less energy input, reduced byproduct load, and streamlined purification. The benefit lands not only with us, but with customers who face audit requirements and must provide certificates proving ethical chemical stewardship up their own supply chain.

    Our team works with customers focused on product life cycle and regulatory compliance. We provide data and real documentation for every batch shipped. This transparency has opened doors to cooperatives and multinational end users, since our compliance track record survives inspection, whether on environmental, health, or product documentation. Whether the material ends up in advanced polymers or niche intermediates, oversight never loosens. Every audit brings back information, feeding continuous improvement that starts in the plant and traces straight through to the final packed drum.

    Solutions to Challenges: Building Trust in Reliable Bromine Chemistry

    The challenge in today’s chemical industry isn’t just turning out material that meets numeric specs; it’s building trust that every batch will handle, react, and perform the same way, every time. Our experience manufacturing 1,4-dibromopentane taught us that solutions always need both a technical and a people-focused side.

    Minimizing impurities relies on honest reporting and batch records. Each vessel is inspected ahead of loading, and in-process samples hit our in-house QA lab at every major stage. This routine brings down the chance of contamination from side chain dihalides—a known headache. Our people raise the alarm if anything seems off, no matter who’s watching the clock. Doing right by the customer means never hiding small problems or missing documentation. The pay-off: long-term clients who come back because past deliveries never left them troubleshooting spectroscopy anomalies at midnight on a deadline.

    On the technical front, feedback loops from buyers show where we must invest—new chromatography protocols, periodic cross-validation, and keeping up with tightening regulations from national and overseas agencies. Digital traceability tied to each drum means if anything’s amiss, both we and our customers have an immediate answer, closing gaps without delay. Training runs year-round for our own teams; every operator, manager, and logistics coordinator is up to date, not just on what’s in the manual but on plant-specific best practices passed down from veteran chemists.

    Looking at broader industry concerns—whether about product stewardship, safety, or shifting supply—no simple fixes exist. Reliable dibrominated intermediates stem from real-world diligence in site management, not just lab-bench optimization. We remain open to sharing what works (and what needed retooling) in our operation, so users trust that what ships meets not only specs on paper but the demands of their own unique project. Over the years, this mindset has made us a preferred partner for clients building long-cycle syntheses or products bound by tight consistency or regulatory demands.

    Final Thoughts: What Sets Manufacturer Experience Apart

    Digging into 1,4-dibromopentane as a manufacturer, the lessons aren’t about surface features or competitive sales slogans. They’re about watching the same reaction run over hundreds of times and knowing exactly where problems show up. They’re about listening to chemists whose work depends on single-digit ppm levels—and being ready to back up every COA with data going back to source. They’re about every operator and technician understanding the routes this chemical travels and should never travel. Even minor discrepancies turn into major issues down the road, whether in the hands of advanced materials labs or multinational production lines.

    Producing 1,4-dibromopentane at scale means tackling all those real-world questions head-on—purity, consistency, documentation, stewardship, reactivity, and safe handling—without glossing over what takes work to get right. Our track record comes from experience, continuous process upgrades, and unwavering transparency. The result isn’t just any dibromoalkane, but one with a track record forged from both chemistry and care, ready for the demanding needs posed by today’s research and industrial sectors.