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1,4-Diacetylbenzene

    • Product Name 1,4-Diacetylbenzene
    • Alias para-Diacetylbenzene
    • Einecs 204-528-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    723770

    Name 1,4-Diacetylbenzene
    Cas Number 613-86-5
    Molecular Formula C10H10O2
    Molecular Weight 162.19 g/mol
    Appearance White to pale yellow crystalline solid
    Melting Point 126-128 °C
    Boiling Point 326 °C
    Density 1.14 g/cm3
    Solubility In Water Insoluble
    Chemical Structure C6H4(COCH3)2

    As an accredited 1,4-Diacetylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,4-Diacetylbenzene, 100g: Supplied in a sealed amber glass bottle with secure screw cap, labeled with chemical details and hazard symbols.
    Shipping 1,4-Diacetylbenzene should be shipped in tightly sealed containers, protected from physical damage and moisture. Transport according to local, national, and international regulations for chemicals. Label appropriately, and include relevant safety data. Avoid contact with strong oxidizers and store in a cool, dry, well-ventilated area during transit to ensure safety.
    Storage 1,4-Diacetylbenzene should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible substances such as strong oxidizers. Protect from moisture and direct sunlight. Properly label the container, and keep it away from food and drink. Use secondary containment to prevent spillage or contamination.
    Application of 1,4-Diacetylbenzene

    Applications of 1,4-Diacetylbenzene in Industrial Manufacturing

    As a specialized manufacturer of 1,4-Diacetylbenzene, we supply this aromatic diketone to leading industrial domains that demand high-purity intermediates for advanced chemical synthesis. Below, we outline key downstream applications based on validated industry usage, highlighting regulatory frameworks, recommended formulation ranges, integration steps within production, and main commercial end products.

    1. High-Performance Polymer Synthesis (Aromatic Polyimides and Polyesters)

    Leading polyimide and high-temperature polyester manufacturers select our material as a critical aromatic diacetyl building block for enhancing polymer backbone rigidity and thermal performance. Due to precise reactivity and defined acetyl placement, this compound enables tailored polymer property control in melt polymerization and solution polycondensation processes for advanced engineering plastics.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management in Polymer Manufacturing)
    • ISO 14001:2015 (Environmental Management for Chemical Processing)
    • RoHS Directive (Restriction of Hazardous Substances for Electronics Polymers)
    • REACH Registration (EU Regulation for Polymer Raw Materials)

    Typical usage ratio

    • 5–25 mol% of total aromatic diacyl components, adjusted based on target glass transition temperature and mechanical specifications

    Downstream process integration

    • Introduced during the acylation (or condensation) stage, after the selection of diamine or diol co-monomer, under controlled temperatures typically between 150–250°C for direct melt-phase or solution polymerization routes

    Final product types

    • Flexible printed circuit substrates
    • High-temperature insulation films
    • Advanced automotive and aerospace structural plastics
    • Precision optics-grade polymer films

    2. Liquid Crystal Material Intermediates

    Manufacturers of advanced liquid crystalline materials incorporate this diketone as a key aromatic core for tuning mesogenic unit structures, impacting phase transition behavior, alignment, and thermal stability in high-end display and electro-optical applications.

    Industry compliance standards

    • IEC 61249-2-7 (Base Materials for Liquid Crystal Polymer Films)
    • JEITA ET-7304 (Japan Electronics and Information Technology Industries Association Standard)
    • OEKO-TEX® Standard 100 (For consumer interface layer safety where applicable)
    • REACH Annex XIV (Regulation of Use in EU Market)

    Typical usage ratio

    • 2–10 mol% of total structural mesogen content, tailored based on desired birefringence and clearing point

    Downstream process integration

    • Added in the condensation assembly of aromatic monomers to form the rigid core structure before side chain introduction and final esterification or etherification steps

    Final product types

    • TFT and OLED liquid crystal display (LCD) materials
    • Optical compensation films
    • High-order parameter display alignment layers

    3. Pharmaceutical Intermediate for Benzene-Derived Active Compounds

    Several pharmaceutical synthesis chains use this aromatic diacetyl raw material as a controlled intermediate to construct specific benzene-based molecular scaffolds where precise substitution enhances bioactivity, facilitating further customization by downstream API manufacturers.

    Industry compliance standards

    • ICH Q7 (GMP for Active Pharmaceutical Ingredients)
    • 21 CFR Part 211 (FDA cGMP for Finished Pharmaceuticals)
    • EP, USP, JP Pharmacopoeia Monographs (Where applicable to subsequent APIs)
    • Good Laboratory Practice (GLP) for process validation

    Typical usage ratio

    • Often utilized in a stoichiometric one-to-one ratio with the nucleophile or amine reactant depending on the final drug molecule, strictly controlled by route-specific process chemistry protocol

    Downstream process integration

    • Undergoes Friedel-Crafts acylation, aldol condensation, or further functional group modification typically in the initial intermediate synthesis or late-stage derivatization depending on target API route

    Final product types

    • Specialty benzene-ring pharmaceuticals
    • Custom API intermediates for oncology and anti-inflammatory drugs
    • Regulated intermediates for advanced synthetic building blocks

    4. Organic Pigments and Dyes Manufacturing

    Colorant producers rely on our product as a diketone precursor for the synthesis of high-purity, high-performance diketopyrrolopyrrole (DPP) pigments and related aromatic dyes, conferring enhanced lightfastness and chroma stability for demanding ink and plastic coloration systems.

    Industry compliance standards

    • EN 71-3 (Migration of Elements for Consumer Pigments)
    • ISO 9001 (Quality Management in Pigment Manufacturing)
    • ASTM D5630 (Loss on Ignition for Organic Colorants)
    • DIN 55943 (Pigments for Plastics)

    Typical usage ratio

    • 1.1–1.5 molar equivalents per pigment-forming amine for diketone coupling reactions, depending on the desired pigment crystal modification and target color index

    Downstream process integration

    • Reacted via condensation with primary aromatic amines in the primary pigment synthesis stage, with post-reaction milling and purification for dispersible colorant grade

    Final product types

    • DPP-based pigments for plastics, automotive, and high-grade printing inks
    • High-stability organic dyes for industrial coatings
    • Masterbatches for fiber and polymer coloration

    5. Specialty Crosslinking Agent in Coating Resins

    Industrial coatings formulators use this compound as a specialty aromatic crosslinker within high-durability resins, enhancing chemical resistance and mechanical integrity in powder coatings and solvent-borne protective finishes for metal substrates.

    Industry compliance standards

    • ISO 12944 (Corrosion Protection of Steel Structures by Protective Paint Systems)
    • ASTM D3359 (Adhesion by Tape Test for Industrial Coatings)
    • REACH Regulation (EU compliance for aromatic constituents)
    • VOC Directive 2004/42/EC (Volatile Organic Compounds for Coatings)

    Typical usage ratio

    • 1–8 wt% in crosslinker component, adjusted based on target film hardness and flexibility standards required by end application (e.g., industrial coatings, automotive powder coatings)

    Downstream process integration

    • Blended into the resin prepolymer mix at the oligomer or pre-cure modification step, then processed through curing ovens at up to 200°C to initiate final network formation

    Final product types

    • Heavy-duty powder coatings for architectural and industrial steel
    • Protective resin-based coatings for automotive underbody parts
    • Chemically resistant tank and machinery surface finishes
    Free Quote

    Competitive 1,4-Diacetylbenzene prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 1,4-Diacetylbenzene: Advancing Material Solutions with Reliability and Performance

    A Manufacturer’s Perspective on 1,4-Diacetylbenzene

    Chemical manufacturing has never been just about pumping out tonnage and shipping drums across continents. Every production run, every batch involves a careful chain of decisions, risk assessments, and quality controls. Over many years in aromatic chemistry, some compounds continue to earn their stripes season after season. 1,4-Diacetylbenzene is one such stalwart. In our facility, we dedicate significant resources to its reliable synthesis, built on methods we’ve refined through persistent experimentation and feedstock optimization.

    Model & Specifications: Direct Knowledge from the Plant Floor

    Our 1,4-Diacetylbenzene (also known as p-Diacetylbenzene) does not arrive as a mysterious chemical handed down by third parties. We produce it with a direct eye on purity and consistency, targeting a high assay with minimal impurities. Production follows systematic acetylation of benzene derivatives, and most of our output lands with an assay level upwards of 99%. Staff chemists monitor the crystallization parameters, keeping an eye on particle morphology and color—practical details that have direct bearing on downstream processing. The substance exhibits a pale crystalline solid appearance. Many customers find its melting point sits comfortably in the expected range, a necessary checkpoint for both organic synthesis and QC laboratories.

    Here, solvent residuals and byproduct content always receive particular scrutiny. The experience gained from batch after batch has shown that water content and colored impurity traces affect client formulations over time, so we habitually run extended drying cycles and employ multiple recrystallizations where warranted. In-house analytical equipment, from gas chromatography to HPLC, allows us to verify against target specifications before each lot leaves our control.

    Applications: Where Our Chemistry Meets Industry’s Demands

    We have watched 1,4-Diacetylbenzene pass through many hands—materials scientists, pharmaceutical chemists, polymer technicians—each with their own expectations and process quirks. In our experience, the robust value comes from its role as an intermediate, particularly in specialty polymers and high-performance resins. Some manufacturers rely on it for producing polyimides, which go into films and fibers for electronic insulation, flexible circuit boards, and advanced aerospace composites. Others have adapted it as a building block for engineered materials requiring durable, heat-resistant structures.

    The compound also finds use as a precursor in fine organic synthesis. Over years of direct feedback, process chemists tell us that the clean reactivity and straightforward methylene group accessibilities make it preferable for multi-step reactions. Well-defined melting profiles and solubility in common organic media eliminate variables when scaling up bench recipes to pilot or production scale. Repeatable behavior in cyclization and crosslinking reactions has also made it a preferred candidate in research programs aiming to modify existing aromatic frameworks.

    Behind the Scenes: What Sets Our 1,4-Diacetylbenzene Apart

    Every batch we prepare reflects hands-on learning. Issues like clumping and inconsistent crystal size, which many buyers face with generic or imported variants, rarely slip past our internal standards. Operators manage agitation and temperature gradients using real-time feedback, dialing in the cooling parameters to promote well-formed, easily handled crystalline lots. These finer touches often start as minor shop floor tweaks but become standard procedure through collective experience.

    Another difference often comes down to isolation and finishing. Many on the outside might underestimate how much effort goes into the final drying stage. Lessons picked up from customer line audits and post-shipment feedback have made us emphasize residual solvent control and batch traceability. This extra attention often prevents downstream bottlenecks, such as solution filtration issues or incompatibility with subsequent reagents.

    A few years back, one of our polymer clients encountered repeated gelation failures in their pilot extruder. Root-cause analysis tracked the fault to trace contamination from a third-party supplier’s product. We invited their team for a plant visit, showed every aspect of our in-line quality monitoring, and shipped fresh samples. Their process stabilized and waste rates dropped. This kind of practical problem-solving persists because of our hands-on exposure—not only to the synthetic chemistry but also to the immediate, daily realities of large-scale manufacturing and supply chain accountability.

    Why Users Demand Consistent 1,4-Diacetylbenzene — Lessons Learned on the Manufacturing Line

    A raw material like 1,4-Diacetylbenzene rarely dominates headlines. But anyone with day-to-day involvement in batch production knows that instability in such a component can derail months of planning. Many long-term customers have shared stories of project delays brought on by even minor variances in their intermediates. Whether a batch crystallizes differently or exhibits inconsistent color, such small deviations introduce inefficiencies batch after batch.

    From a producer’s perspective, controlling these details stems from a process mindset rooted in daily operational rigor. Our technicians not only follow documented instructions—we keep working notebooks on process adjustments, anomalous events, and corrective actions. Anomalous blue or yellow tints in product fractions, for instance, tip us off to upstream feed purity slips or lingering process residues. Because our production remains vertically integrated, we quickly introduce new purification steps if test results shift. There’s no need for rushed external troubleshooting or passing responsibility down the line.

    Comparing 1,4-Diacetylbenzene with Related Compounds in Practice

    Questions about differences between 1,4-Diacetylbenzene and its isomeric or homologous counterparts occur regularly. Some polymer engineers debate the merits of using this para-substituted acetylbenzene versus its meta- or ortho-analogs. Actual usage in the production plant shows that 1,4-Diacetylbenzene gives more predictable polymerization due to the symmetry it imparts, leading to cleaner reaction cascades and fewer unwanted side-products. When synthesizing certain polyarylenes or linear aromatic chains, this regularity substantially cuts down on purification costs and time.

    Similarly, single-acetyl derivatives such as acetophenone (with only one acetyl group) cannot offer the same functional density. Our clients in advanced plastics report achieving higher molecular weight backbones and better end-use properties with 1,4-Diacetylbenzene as the core, confirming bench-scale findings. We have seen simple substitutions result in unwelcome changes to glass transition temperatures and melt processability—not academic trivia, but concrete headaches for production teams tasked with meeting performance contracts.

    Comparisons also arise with diacetylbenzenes featuring acetyl groups in positions other than 1,4. Those alternatives often complicate downstream chemistry or introduce unwanted branching. Real-world testing shows increased batch waste and unhelpful viscosity shifts, with process engineers returning to our 1,4-Diacetylbenzene as a way to restore reliable plant metrics. The result is not only a matter of purity, but of backbone structure, as processing lines and product performance both benefit from this regularity.

    Manufacturing Challenges: What We’ve Learned and How We Adapt

    Manufacturing 1,4-Diacetylbenzene at scale is not a fire-and-forget operation. Occasionally, global shifts in benzene prices or supply chain events push us to rethink sourcing and stock levels. Direct experience handling xylene streams and managing catalyst procurement means our supply team works months ahead, often balancing forward contracts with just-in-time inventory for crucial reagents. During periods of increased demand, competing for premium-grade acetyl donors forces us to accelerate process optimization without sacrificing product integrity.

    Utility reliability plays a huge role in day-to-day output. Several years ago, voltage fluctuations during a scheduled maintenance upset the temperature control in our acetylation reactor, impacting the batch profile and requiring additional purification runs. Incidents like these pushed us toward investment in backup generator systems and remote monitoring. Each technology choice is guided by the real demands of chemical processing, not simply budget lines or off-the-shelf solutions.

    Staff training counts for just as much as equipment. We constantly hone our teams’ skills, pairing senior technicians with newer staff to pass down hard-won process wisdom—such as managing unusual foaming in mother liquor or coping with off-specification starting material. Routine team debriefs after each production cycle have proven themselves invaluable in catching irregularities before they become systemic risks. These are not “box-ticking” exercises for audits, but practical, results-driven steps that feed back into every subsequent run. The end goal is not only high-yield batches, but dependable product every time.

    Quality Assurance: Where Practice Outpaces Theory

    Chemical manufacturing breeds caution for good reason. Procedures in the quality department go well beyond minimum compliance. We’ve found daily reference standard checks, internal split-sample analyses between day and night shifts, and redundant cross-referencing of HPLC readings all translate to tighter control. Any blips trigger root-cause investigations rather than quick fixes. The result is a supply chain partner who believes in transparency and records data not just for audits, but for practical feedback and ongoing improvement.

    Clients routinely audit our processes, often sending their own analysts to shadow ours. These open-door practices encourage real conversation about challenges and mutual learning. Working on both sides of regulatory submissions has shown us that quality documentation should be living and responsive, not set in stone at one point in time. Labels might call for “Meets USP” or “Conforms to JIS,” but our routine and outlier data dive much deeper to shield customers from costly surprises and process hiccups.

    Reliability through Traceability: Building Trust Step by Step

    Supply reliability matters most when every other link in the value chain appears shaky. During major transport disruptions and volatile markets, the value of robust traceability systems cannot be overstated. Every drum, each batch can be traced back through multi-stage logs—starting reagent lots, operator notations, equipment runs, test checkpoints—right up to final goods issue. These systems are as critical for our own legal and compliance peace of mind as they are to customers operating under tight regulatory oversight.

    Several procurement managers have commended us on the clarity of our batch histories, particularly during strict customs inspections or sudden third-party audits. Years spent responding to data requests taught us that speed and documentation accuracy can turn potential shipment delays into straightforward resolutions. This means open, unembellished access to relevant documents, and not passing requests through distant sales offices or unrelated brokers.

    Customer Support: Continuous Improvement Drives Our Product Forward

    Real-world support does not end with a bill of lading or paper certificate. Process engineers often phone in with new performance questions, such as how our 1,4-Diacetylbenzene responds to different solvents or whether micronization impacts reactivity. Because our plant staff maintain records not only on what left the door but also on previously trialed production tweaks, we quickly dig into archived process details or run custom tests. This hands-on approach creates long-term supplier relationships and helps transfer production know-how from our facility to theirs.

    Collaborative troubleshooting lies at the core of our support ethos. Sometimes, a customer’s line stops because their previous supplier altered parameters without notice; sometimes their own scaling introduces unanticipated crystallization challenges. Either way, our plant and technical teams often travel out to customer sites, bringing product samples, analysis records, and—importantly—direct insight into how to modify processes for a stronger final result.

    Sustainability & Regulatory Footing: Practical Steps in an Evolving Sector

    Environmental stewardship becomes more real when it ties to actual production floors. Years of working with waste generation, emission controls, and resource optimization have shown that sustainability is not a buzzword but a process of continuous improvement. Here, waste minimization efforts include strict solvent recycling and energy recuperation from process heat. Regulatory compliance is ongoing, woven through daily operator checklists and periodic environmental audits. Where many see looming costs, experience shows early investment in robust safety and documentation practices repays itself many times over. We do not sit still when global or regional standards shift, and quickly integrate updated protocols into practical steps, not just paperwork exercises.

    Looking Forward: Continuous Evolution for Industry Needs

    The ever-shifting landscape of specialty chemicals and advanced materials manufacturing keeps challenging us to sharpen every aspect of our operations. Emerging trends in electronics, high-strength polymers, and sustainability shape the future demand for 1,4-Diacetylbenzene. We stay open to novel requests—whether they come as questions from independent labs or as scale-up support for global manufacturers. Our commitment runs deeper than filling orders; it is rooted in persistent learning and on-the-floor process control, matched by willingness to tackle new hurdles alongside our clients.

    Every kilogram of 1,4-Diacetylbenzene that leaves our production line carries with it the fingerprints of countless hours of adjustment, observation, and direct feedback—a product whose reliability and purity arise not from chance, but from disciplined, ongoing engagement with the many challenges of modern chemical manufacturing. Those seeking a dependable, high-performance intermediate need more than a label or a number; they demand a supplier with proven experience, resilient infrastructure, and a record of customer-focused improvement. For those in search of trustworthy 1,4-Diacetylbenzene, we remain ready to share both our product and our on-the-ground know-how, forged over years of chemical craftsmanship.