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1,4-Cyclohexanediol

    • Product Name 1,4-Cyclohexanediol
    • Alias Hydroquinolyl alcohol
    • Einecs 208-683-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    120128

    Cas Number 556-48-9
    Molecular Formula C6H12O2
    Molecular Weight 116.16 g/mol
    Iupac Name Cyclohexane-1,4-diol
    Appearance White crystalline solid
    Melting Point 104-107 °C
    Boiling Point 245 °C
    Density 1.18 g/cm³
    Solubility In Water Soluble
    Flash Point 120 °C
    Pubchem Cid 11579
    Structural Formula C6H10(OH)2
    Refractive Index 1.472
    Odor Odorless
    Synonyms 1,4-Dihydroxycyclohexane

    As an accredited 1,4-Cyclohexanediol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1,4-Cyclohexanediol is packaged in a 500-gram amber glass bottle with a secure screw cap and hazard labeling.
    Shipping 1,4-Cyclohexanediol should be shipped in tightly sealed containers, protected from moisture and direct sunlight. It should be handled as a chemical product, following relevant regulations. During transport, keep away from incompatible substances such as strong oxidizers. Label packages clearly and ensure compliance with local and international shipping guidelines for chemicals.
    Storage 1,4-Cyclohexanediol should be stored in a tightly sealed container in a cool, dry, well-ventilated area, away from sources of heat, ignition, and incompatible materials such as strong oxidizing agents. Protect it from moisture and direct sunlight. Proper labeling and secure storage are recommended to prevent accidental exposure or spillage. Always follow standard laboratory safety protocols when handling and storing this chemical.
    Application of 1,4-Cyclohexanediol

    Applications of 1,4-Cyclohexanediol in Industrial Manufacturing

    1,4-Cyclohexanediol serves critical roles as an intermediate and performance enhancer in several industrial manufacturing sectors. Our direct supply supports stringent quality control throughout downstream production. Detailed below are the primary industrial applications, covering regulatory requirements, dosage references, integration processes, and key final products within each segment.

    1. Polymer Modification in Engineering Plastics

    Polymer producers incorporate this diol derivative to adjust the flexibility, durability, and clarity in select engineering plastics. The material reacts with phthalic or terephthalic acid derivatives in condensation polymerization, optimizing the physical properties of polyesters and copolymers for molded components and high-performance films. For each grade, compliance and traceability occur throughout compounding and pelletizing stages for reliable integration into demanding technical specifications.

    Industry compliance standards

    • ISO 9001:2015 for quality management during plastics compounding
    • EN 15593 for materials intended for food-contact packaging plastics
    • REACH Regulation (EC) No 1907/2006 for chemical registration and safety documentation
    • UL Yellow Card Certification (specific resin grades, if required by OEMs)

    Typical usage ratio

    • 5–25% by weight in polyesters or copolymers, subject to formulation targets for impact resistance and clarity; proportion adjusted based on desired melt flow, toughness, and compatibility with other diols or glycol modifiers.

    Downstream process integration

    • Introduced during esterification or polycondensation with dicarboxylic acids in reactor; monitored via in-process viscosity and molecular weight control, then carried forward through extrusion and pelletizing lines.

    Final product types

    • Automotive instrument panels and housings
    • Consumer electronics casings
    • Food-grade polyester films
    • Specialty copolyester resin pellets for sheet extrusion

    2. Synthesis of Specialty Coating Resins

    This molecular diol is utilized in high-performance alkyd, polyester, and polyurethane resin formulations for coatings. It enhances flexibility, solvent resistance, and weatherability for industrial finishes, metal coatings, and automotive clearcoats. Analytical controls confirm complete incorporation during prepolymer synthesis or resin blending, ensuring batch consistency and regulatory conformity for each customer’s application.

    Industry compliance standards

    • ASTM D968 (abrasion resistance testing for coatings)
    • RoHS Directive 2011/65/EU for restriction of hazardous substances on coated end-use articles
    • ISO 12944 for corrosion protection of steel structures by protective coatings
    • DIN EN 927 for exterior wood coatings

    Typical usage ratio

    • 3–18% by weight, based on resin formulation and desired crosslink density; precise dosage determined by balance of chemical resistance and mechanical flexibility required for the end application.

    Downstream process integration

    • Added during controlled polycondensation synthesis of alkyd or polyester backbone; may serve as a chain extender or reactive diluent in polyurethane prepolymerization before final pigment and additive blending.

    Final product types

    • Automotive clearcoat and basecoat systems
    • Industrial anti-corrosion primers
    • Protective metal and marine coatings
    • Outdoor architectural wood finishes

    3. Production of Plasticizers for Flexible PVC Compounds

    This diol intermediate is converted by esterification into cyclohexane diol-based esters, serving as non-phthalate plasticizers for flexible PVC. These esters impart low volatility, migration resistance, and improved cold flexibility in wire cable insulation, flooring, and synthetic leather manufacturing. Downstream users value its compliance with non-toxic ISO and European Union chemical safety requirements for contact-sensitive products.

    Industry compliance standards

    • REACH Annex XVII for phthalate alternatives (plasticizer regulations)
    • EN 71-3:2019 for safety of toys – migration of certain elements
    • ISO 18254-2 for testing plasticizer migration in PVC
    • UL 94 for flame retardant performance (dependent on end article)

    Typical usage ratio

    • 15–45% by total weight of PVC formulation; final dosage tailored to softening requirements, tensile properties, and environmental migration specifications for targeted end products.

    Downstream process integration

    • Converted to dialkyl esters in dedicated esterification reactors; plasticizer then blended with PVC resin and stabilizers during compounding, preceding calendaring or extrusion of finished products.

    Final product types

    • Soft PVC cable jacketing
    • Resilient flooring tiles and sheeting
    • Flexible synthetic leather coverings
    • Inflatable consumer goods and toys

    4. Raw Material in Pharmaceutical Intermediate Synthesis

    Pharmaceutical manufacturers employ this diol as a structurally defined building block for synthesis of select active ingredients and advanced intermediates. The compound supports stereocontrolled reactions yielding cyclohexane-containing drug entities, where batch reproducibility and impurity control remain critical for regulatory submissions and finished dosage manufacture.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP-NF (United States Pharmacopeia–National Formulary) for advanced intermediate quality
    • EDQM CEP (Certificate of Suitability) for registered starting materials
    • EU GMP Directives for traceability and process validation

    Typical usage ratio

    • Usage level typically 1–20% stepwise in multi-stage syntheses, amount driven by stoichiometry in intermediate step; full integration depends on target API structure and desired yield optimization.

    Downstream process integration

    • Introduced in nucleophilic substitution or cyclization steps; purified via crystallization or distillation to meet pharmaceutical-grade purity before subsequent chemical conversions.

    Final product types

    • Specific cyclohexane-based pharmaceutical intermediates
    • Active pharmaceutical ingredient precursors
    • Patented drug substance intermediates for CNS and metabolic treatments
    • Chiral building blocks for select fine chemicals

    5. Monomer Feedstock in Polycarbonate and Polyurethane Manufacture

    The material functions as a specialty diol monomer for polycarbonate diol and select polyurethane chains. Its unique cycloaliphatic structure imparts hydrolytic stability and better mechanical properties for automotive, medical, and high-value industrial parts. Quality control measures authenticate starting material for regulated applications and enable trace supply chain documentation.

    Industry compliance standards

    • ISO 10993 for biocompatibility (medical device-grade materials)
    • FDA CFR Title 21 for food contact substances (polycarbonate use)
    • ISO 14001 for environmental management in polymer manufacturing plants
    • OEKO-TEX® Standard 100 for textile auxiliary material approval

    Typical usage ratio

    • 5–30 mol% of total diol content in polycarbonate or polyurethane formulations; proportion selected to balance hardness, elongation, solvent resistance, and processability for the designated article.

    Downstream process integration

    • Directly charged to reactor alongside carbonate diesters or diisocyanates; diol content monitored by HPLC or GC analysis for accurate chain length and cross-link establishment prior to extrusion or casting.

    Final product types

    • Medical polycarbonate tubing and housings
    • High-performance industrial polyurethane wheels
    • Automotive interior polyurethane coatings and foams
    • Technical coated textile backings
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    Certification & Compliance
    More Introduction

    1,4-Cyclohexanediol: An Everyday Essential in Chemical Production

    Our Experience in Manufacturing 1,4-Cyclohexanediol

    Over three decades in the specialty chemical business have shown us how certain substances often work quietly behind the scenes, making modern production possible. 1,4-Cyclohexanediol, which our team customizes in both technical and high-purity variants, serves as one of those dependable workhorses across resin, polymer, and coating applications. On the plant floor, our skilled operators ensure every lot meets tight color and purity controls, minimizing water and trace contamination. It’s a record built on consistency—every drum comes with a certificate tied directly back to our internal QC runs.

    Understanding the Basics: Appearance, Purity, and Practical Features

    Customers regularly ask about the appearance of 1,4-Cyclohexanediol in shipping containers. In our experience, quality material always travels as a white, crystalline solid, stable up to moderate temperatures. The product melts cleanly without scorched residue, providing a reliable starting point for further transformation. We produce typical grades with purity levels exceeding 99%, measured by HPLC and gas chromatography, since many downstream uses—polyester resins, for instance—fail if impurities rise much above 1%. Rigorous batch records and a hands-on lab crew back up these purity claims, and our site retains reference samples for traceability.

    Where Manufacturers Use 1,4-Cyclohexanediol

    Today’s manufacturing relies on a surprising number of specialty intermediates. Among diols, 1,4-Cyclohexanediol offers manufacturers a unique molecular backbone. Its cycloaliphatic ring brings rigidity to every polymer chain it enters, unlocking properties like chemical stability and improved glass transition temperatures in thermoplastics. Our resin and plasticizer customers particularly value how this structure delivers toughness without adding aromatic character that can yellow or weaken over time. In waterborne systems, the hydroxyl groups make blending into formulations straightforward, reflecting the clean, accessible reactive sites on the molecule.

    Differences from Other Diols in Application and Chemistry

    We often get comparisons with conventional 1,4-butanediol and even ethylene glycol. 1,4-Cyclohexanediol stands out due to its ring structure—a point our in-house chemists test regularly in the lab. Such a cycloaliphatic ring brings a different flexibility-stiffness balance than linear or branched diols. In polyester, polycarbonate, and specialty polyurethane synthesis, this difference translates to real-world gains in transparency and weather resistance. Surface coatings built with our product resist water and maintain clarity, even where cyclic UV exposure stresses the base. That’s not a fluke; we tweak reaction parameters consistently to maximize reproducible performance in these tough conditions.

    Linear diols pass on greater flexibility to end polymers, which often suits applications like soft foam, plasticizers, or elastomers. 1,4-Cyclohexanediol, in contrast, brings cycloaliphatic stability and less reactive aldehyde or acid formation during processing. This unique chemistry lowers the chance of unwanted byproducts, especially during high-temperature reactions. Our production routes only use top-grade hydrogenation catalysts, cutting down risk of over-reduction or stereoisomerism, so the product feeds seamlessly into modern polymerization lines.

    Specifications: Why They Matter in Real Manufacturing

    Specifications are more than a checkbox exercise here. Our plants control moisture content, heavy metal residuals, and organic impurities in line with the most demanding resin and coating standards. Experience tells us that even small spikes in iron or copper content cause unpredictable yellowing downstream, so we analyze each batch using atomic absorption and ICP-MS where needed. We stick to labeling lots with NMR and FTIR verification to identify any departures from the expected diol profile. These details matter to both automotive finishers needing non-yellowing clearcoats and film packaging groups seeking exacting transparency.

    We test each finished lot for bulk density, particle size distribution, and solubility in multiple common solvents, knowing that pourability and easy blending cut production time for our customers. Bulk packaging lines operate under nitrogen to prevent any unwanted oxidation before drum sealing. Our logistics team has designed a protocol that balances fast turnaround—often crucial for custom orders—with triple checks to prevent cross-contamination, right down to pre-flushes on tanker trucks.

    Collaboration in Usage: Supporting Problem Solving

    Every real project brings its own wrinkles. We’ve worked side-by-side with process engineers tackling unusual melt-process resins, helping pinpoint the right 1,4-Cyclohexanediol grade and form. High-purity needs pop up where optical properties rule, so we adjust our solvent-washing approach and tweak purification cycles to guarantee colorless, clear product. Where adhesive producers report shelf-life shortfall, our technical support crew reviews storage conditions and collaborates with their QC teams to rule out container leaching or trace oxidizer introduction.

    Dynamic epoxy and polyester resin producers sometimes press for tighter limits on certain trace organics. To address this, we modify conditions in our crystallization step, gaining finer control over impurity fractions. In a joint pilot with a European coatings customer, our lab supplied different particle size grades so their process engineers could adapt batch times and temperatures for optimum dispersion. These lessons, built from real-world engagement, have steadily improved our product offerings for the whole market.

    Environmental and Safety Factors Shaping Supply

    In the chemical industry, increasingly strict safety and disposal regulations affect how we make, ship, and store 1,4-Cyclohexanediol. One example involves minimizing process waste and emissions. Our site reclaims effluent for reuse in side-processes and applies closed-loop systems to keep vapor release below regional requirements. During winter months, our packaging team adds insulation and weatherproofing where necessary, since the solid form tends to clump if exposed to damp or low temperatures. Our safety office routinely revises handling guidelines after working through incident reviews and customer feedback.

    Regarding transportation, we select only carriers with proper bulk chemical certifications and serialization systems. Tracking every shipment minimizes loss, maintains accountability, and ensures compliance at border crossings. For customers using our product in regulated environments—such as medical intermediates or sensitive electronics—the extra traceability means fewer delays and confidence in the final supply chain.

    Product Usage: Lessons from the Factory Floor

    On the polymerization line, production managers look for feedstock that flows and melts without hang-ups. From our trials, 1,4-Cyclohexanediol only rarely cakes or bridges in standard feeding hoppers provided ambient moisture is controlled. Power plant and plastics teams place great stock in this, as downtime costs mount quickly if a bin jam occurs or product doesn’t dissolve smoothly in the reaction vessel.

    Small changes in moisture content may seem trivial on paper but shift polymer performance measurably. For foam and coating applications, our recommendation to strictly monitor drum resealing procedures and rotate stock according to manufacture date has helped many buyers extend their material’s working life. Our floor techs stress not opening containers outside of controlled environments, and we follow up with customers to review storage protocols, returning insights into our next packaging design upgrades.

    1,4-Cyclohexanediol’s Edge in Polymer and Resin Chemistry

    The cycloaliphatic structure of this diol unlocks higher glass transition temperatures and better weathering in finished thermosets. We see consistent demand from groups pitting polyester resins against aggressive outdoor or UV-exposed environments. The property set—chemical resistance, low color formation, and high clarity—makes it a strong choice compared to traditional flexible diols. In epoxy formulation, the diol hardens networks while retaining workable elasticity, and doesn’t generate troublesome aromatic byproducts.

    For specialty coatings and inks, our ongoing partnerships have shown that fine-tuning hydroxyl value and particle size at the supplier stage trims hours from grinding and mixing times in customer plants. We’ve piloted custom granulation and micronization approaches for groups aiming to move away from solventborne systems, supporting a shift toward waterborne and powder coatings. These insights come not just from lab notes, but from continuous on-site collaboration—troubleshooting batch variation, developing anti-caking packaging, and offering on-call advice for new plant start-ups.

    Reliability and Long-Term Value

    Chemical buyers need to trust that every container of 1,4-Cyclohexanediol delivers enough performance, regardless of production scale. Some customers buy by the pallet, others contract for truckloads with tight delivery windows. In both cases, our longstanding relationships with transport partners and quarterly audits of returnable packaging fleets keep the product arriving in good condition. Distributors trust our track record, but our support runs deeper. For any batch issue or out-of-spec shipment, engineers from our site head directly to the customer facility, reviewing usage and running parallel QC tests at our lab to isolate root causes.

    Lean manufacturing can expose the seams in many upstream processes. Fast response times, reliable technical documentation, and a willingness to adapt drum, big-bag, or tote sizes according to plant demand keeps our order cycles sharply aligned to customer needs. Forecasting helps a great deal, but direct feedback from our customer partners shapes our annual investment—larger reactor vessels, cleaner filtrations, or lab-scale optimization units all reflect that steady dialogue.

    Different Needs for Different Sectors

    Plastics and resins set the largest baseline for 1,4-Cyclohexanediol consumption. This isn’t the whole story. In recent years, we’ve seen a surge in technical demand from adhesives, specialty elastomers, and high-performance polyurethane projects. Optical and medical-grade polymers use our highest-purity stocks, skipping dyes and secondary antioxidants. In coatings, a tight color spec and sharp particle sizing ensure clear finish and UV-resisting applications—automotive, marine, and architectural exterior. Our plant now runs separate lines for food packaging and medical projects, enforcing strict internal protocols around raw material segregation, batch tracking, and allergen risk review.

    Energy storage, too, turns out to be a growing field. Battery separator films and certain specialty electrolytes use our product for structural and reactive backbone. These applications demand higher molecular stability, so our lab prioritizes accelerated aging tests and real-time shelf-life studies. Fast material innovation in these sectors means we keep a pilot reactor on standby, tweaking process variables for test runs and customer validation.

    Supporting New Solutions: Beyond Basic Commodity Supply

    Some producers view chemicals purely as line commodities, but our team handles more nuanced technical requests every week. Producing new copolymer blends for emerging markets, adjusting impurity tolerances for food packaging, and collaborating with additive designers for custom stabilization packages now make up a sizable share of our development time. We draw on our manufacturing history—not just lab synthesis, but raw material sourcing and operations troubleshooting at full plant scale. By working in lockstep with both research chemists and plant operations teams, we’ve resolved real bottlenecks in downstream manufacturing.

    A recent example involves a customer switching away from bisphenol-A due to regulatory and consumer pressure. Our team worked cross-functionally to certify 1,4-Cyclohexanediol in new BPA-free polymer blends, running pilot batches to meet both migration and mechanical test standards. That’s where experience on the manufacturing side—knowing the realities of batch consistency, impurity leaching, and practical shipping constraints—makes all the difference compared to a typical commodity outfit.

    What Reliability Means for Tomorrow’s Producers

    History has shown us that chemical manufacturing success hinges on more than laboratory numbers. The consistent, hands-on approach to quality, safety, and technical support translates directly to reliability for customers re-engineering their own products. As regulatory and market pressures build, those making films, coatings, and specialty polymers need suppliers who anticipate shifts in demand and compliance. We meet regular audits from world-leading resin, packaging, and electronic firms—sometimes spending days in their plants ensuring our batches perform as expected. Their feedback informs our risk assessment, process validation, and continuous improvement.

    Every kilogram of 1,4-Cyclohexanediol we ship stays traceable back to the distillation and crystallization records at our site. That disciplined approach stands behind the performance seen in our customers’ factories, supporting them as they adapt to ever-stricter market and consumer standards. Looking forward, we expect a continued move toward specialty blends, greener process routes, and custom packaging formats. Our direct experience as long-time manufacturers keeps us focused on what matters: supplying a product that keeps pace with new technologies, while standing up to practical, real-world demands.